Introduction Dermatophytosis is a common infection of the skin, hair, and nails caused by dermatophytes, a group of filamentous fungi capable of digesting and obtaining nutrients from keratin. Dermatophytes comprise three important genera: Epidermophyton, Microsporum,and Trichophyton. This study aimed to analyze the antifungal susceptibility patterns of Trichophyton mentagrophytes isolates using the epsilometer test (E-test) method. Material and methods This prospective observational study was conducted on clinically suspected cases of dermatophytosis. All samples, including skin scrapings, hair, and nails, were subjected to potassium hydroxide (KOH) examination followed by fungal culture. The Trichophyton mentagrophytes isolates were then subjected to antifungal susceptibility testing using the E-test method for the two most prescribed antifungals: itraconazole and fluconazole. Results In this study, one-third of the patients who tested positive for dermatophytosis belonged to the same family, with spouses being the most commonly affected. Tinea corporis was the most common clinical presentation, with Trichophyton mentagrophytes identified as the most common etiological agent. Itraconazole was more effective than fluconazole. Conclusion The current study demonstrated that antifungal susceptibility testing of dermatophytes using the E-test is easier and can be applied in routine laboratories as a screening method, serving as an alternative to broth microdilution.

暂无摘要。

UNASSIGNED: Risk factors for the persistence of superficial skin infestations are prevalent in humid tropical environments, which are favorable for breeding of the causative vector mite Sarcoptes scabiei (ectoparasite) and dermatophyte fungi.
UNASSIGNED: This study aimed at assessing the awareness and knowledge of childhood scabies and ringworm infestations among parents in Calabar, a highly humid rainforest tropical environment.
UNASSIGNED: Cross-sectional study design and systematic random sampling were used to recruit school-age children in selected primary schools in Calabar.
UNASSIGNED: Researcher-driven administration of a structured questionnaire was conducted to obtain quantitative data from parents of recruited children.
UNASSIGNED: : Chi-square was used to assess factors associated with ever hearing or seeing scabies and ringworm infestations. Statistical significance was set at P < 0.05.
UNASSIGNED: One hundred and eighty-two (56.7%) and 218 (67.9%) of the respondents had heard of or seen scabies and ringworm infestation. Among respondents that were aware of scabies, 53.3% knew of the cause, 50.5% were aware of the risk factors while 68.1% and 78.0% knew their treatment and prevention, respectively; 98.6%, 60.6%, 76.6%, and 80.7% of respondents knew the cause, risk factors, treatment, and prevention of ringworm infestation, respectively. Fathers with at least secondary school literacy level and sharing beds were significantly associated with awareness of scabies.
UNASSIGNED: There is a suboptimal level of awareness and knowledge of two of the most common superficial skin infestations among parents of primary school children in the study setting. There is a need to redouble our effort at sensitization of parents toward improved awareness of these common infestations.
Résumé Contexte: Les facteurs de risque de persistance des infestations cutanées superficielles sont prévalents dans les environnements tropicaux humides, favorables à la reproduction du vecteur responsable, la gale Sarcoptes scabiei (ectoparasite), et des champignons dermatophytes. Objectif : Cette étude visait à évaluer la sensibilisation et les connaissances des parents de Calabar, un environnement tropical de forêt équatoriale très humide, concernant la gale et les infestations à la teigne chez les enfants. Cadre et conception : Une étude transversale et un échantillonnage systématique ont été utilisés pour recruter des enfants d\'âge scolaire dans des écoles primaires sélectionnées à Calabar. Méthodes et matériel: Une administration dirigée par le chercheur d\'un questionnaire structuré a été réalisée pour obtenir des données quantitatives auprès des parents des enfants recrutés. Analyse statistique utilisée: Le test du chi carré a été utilisé pour évaluer les facteurs associés à la connaissance de la gale et des infestations à la teigne. La signification statistique a été fixée à P < 0,05. Résultats: Cent quatre-vingt-deux (56,7 %) et 218 (67,9 %) des répondants avaient entendu parler ou vu une infestation de gale et de teigne. Parmi les répondants qui étaient au courant de la gale, 53,3 % connaissaient la cause, 50,5 % étaient conscients des facteurs de risque, tandis que 68,1 % et 78,0 % connaissaient respectivement leur traitement et leur prévention. De même, 98,6 %, 60,6 %, 76,6 % et 80,7 % des répondants connaissaient respectivement la cause, les facteurs de risque, le traitement et la prévention de l\'infestation à la teigne. Les pères ayant au moins un niveau d\'alphabétisation au niveau secondaire et partageant des lits étaient significativement associés à la connaissance de la gale. Conclusion: Il existe un niveau sous-optimal de sensibilisation et de connaissance de deux des infestations cutanées superficielles les plus courantes parmi les parents d\'enfants d\'école primaire dans le cadre de l\'étude. Il est nécessaire de redoubler d\'efforts pour sensibiliser les parents afin d\'améliorer la connaissance de ces infestations courantes. Mots-clés: Infestations cutanées, gale, teigne, connaissance, parents, enfants d\'âge scolaire, Nigeria.

To limit the spread of bovine ringworm, control measures such as movement restrictions are highly recommended. In this context, calves at auction markets in Styria, Austria, displaying skin lesions characteristic for bovine ringworm, are excluded from the auctions. To investigate whether these clinical assessments correspond to laboratory diagnosis, a total of 166 samples taken from skin lesions assigned to the three clinical categories \'ringworm very likely (v), likely (l) or unlikely (u)\' were mycologically examined using microscopy, culture, and nested PCR followed by amplicon sequencing. Further, the relationships of isolated dermatophytes were determined through multi-locus sequence typing (MLST). Overall, a high agreement between clinical assessment and laboratory results were observed with microscopy and nested PCR, providing more consistent results and molecular detection possessing an analytical sensitivity superior to that of cultural isolation (culture 21.7% vs. nested PCR 48.2%). Phylogenetic analyses revealed that most of the isolated dermatophytes belong to a unique Trichophyton verrucosum MLST genotype. In conclusion, clinical assessments were largely confirmed through laboratory diagnosis with nested PCR and sequencing, providing rapid, sensitive, and species-specific detection of dermatophytes in calves at auction markets displaying skin lesions typical for ringworm; this seems to be predominantly caused by a single Trichophyton verrucosum strain.

Background and Objectives: Before the introduction of griseofluvin, the use of X-ray radiation was the treatment of choice for tinea capitis. More than half a century later various types of tumors have been found to be associated with childhood irradiation due to tinea capitis, most commonly cancers of the head and neck, as well as brain tumors. The often unusually aggressive and recurrent nature of these tumors necessitates the need for repeated surgeries, while the atrophic skin with an impaired vascular supply due to radiation often poses an additional challenge for defect reconstruction. We present our experience in the surgical treatment of such patients. Materials and Methods: This is a retrospective cohort study. In this study, 37 patients treated for acquired defects of the scalp with a history of irradiation therapy due to tinea capitis in childhood were included in this study, 24 male and 13 female patients. The mean age at the first appointment was 60.6 ± 7.8, with the youngest included patient being 46 and the oldest being 75 years old. Patients\' characteristics, surgical treatment, and complications were analyzed and a reconstructive algorithm was developed. Results: Local flaps were used for reconstruction in 34 patients, direct sutures were used in 10 patients and 20 patients received split-thickness skin grafts for coverage of both primary and secondary defects for reconstruction of flap donor sites. One regional flap and one dermal substitute covered by an autologous skin graft were also used for reconstruction. Complications occurred in 43.2% of patients and were significantly associated with the presence of comorbidities (p = 0.001), aseptic bone necrosis (p = 0.001), as well as skin atrophy in frontal, occipital, and parietal region (p = 0.001, p = 0.042 and p = 0.001, respectively). A significant correlation between major complications and moderate skin atrophy was found only in the parietal region (p = 0.026). Conclusions: Unfortunately, many protocols developed for scalp reconstruction are not applicable in the setting of severe or diffuse scalp skin atrophy associated with high tumor recurrence rate and radiation-induced vascular impairment, such as in tinea capitis patients in Serbia. An algorithm has been developed based on the authors\' experience in managing these patients.

BACKGROUND: Dermatophytosis (ringworm) caused by members of the Trichophyton mentagrophytes complex is rarely diagnosed in pigs but has been recognized as an increasingly common infection in humans. Further, resistance to antifungal drugs have been reported both in Asia and in Europe. This is the first scientific report of infection by the T. mentagrophytes complex in pigs in the Nordic countries.
METHODS: Skin lesions developed in grower pigs in an organic fattening pig farm with outdoor production and following laboratory analyses, dermatophytosis caused by members of the T. mentagrophytes complex was diagnosed. Infection was linked to poor hygiene, high humidity, and moderate outdoor temperatures, in combination with high pig density. A farm worker developed a skin lesion after close contact with affected pigs, which highlighted the zoonotic potential of porcine dermatophytosis. The dermatophytes may have originated from the herd supplying the growers where similar lesions occurred in pigs. Further, pigs from another organic fattening herd that received growers from the same supplier herd also developed dermatophytosis. The lesions healed without treatment as the housing conditions were improved. Isolation of affected pigs prevented spread to other pigs CONCLUSION: Members of the T. mentagrophytes complex can cause ringworm in pigs. The fungi probably persist in the haircoat and may cause overt disease when environmental conditions promote growth of mycelia.

BACKGROUND: Mallory-Weiss syndrome (MWS), representing a linear mucosal laceration at the gastroesophageal junction, is a quite frequent cause of upper gastrointestinal bleeding, usually induced by habitual vomiting. The subsequent cardiac ulceration in this condition is likely due to the concomitance of increased intragastric pressure and inappropriate closure of the gastroesophageal sphincter, collectively inducing ischemic mucosal damage. Usually, MWS is associated with all vomiting conditions, but it has also been described as a complication of prolonged endoscopic procedures or ingested foreign bodies.
METHODS: We described herein a case of upper gastrointestinal bleeding in a 16-year-old girl with MWS and chronic psychiatric distress, the latter of which deteriorated following her parents\' divorce. The patient, who was residing on a small island during the coronavirus disease 2019 pandemic lockdown period, presented with a 2-mo history of habitual vomiting, hematemesis, and a slight depressive mood. Ultimately, a huge intragastric obstructive trichobezoar was detected and discovered to be due to a hidden habit of continuously eating her own hair; this habit had persisted for the past 5 years until a drastic reduction in food intake and corresponding weight loss occurred. The relative isolation in her living status without school attendance had worsened her compulsory habit. The hair agglomeration had reached such enormous dimensions and its firmness was so hard that its potential for endoscopic treatment was judged to be impossible. The patient underwent surgical intervention instead, which culminated in complete removal of the mass.
CONCLUSIONS: According to our knowledge, this is the first-ever described case of MWS due to an excessively large trichobezoar.

Panwad (Cassia tora L.), Sarshaf (Brassica nigra L.) and Kunjad (Sesamum indicum L.) have been used in the treatment of ringworm infection since ancient times and are documented in classical literature of Unani Medicine. These plant drugs give promising results when used topically in the form of paste (zimad). Hence, the development and evaluation of a cream containing extracts of Tukhm-e-Panwad (Cassia tora L.), Sarshaf (Brassica nigra L.), and Kunjad (Sesamum indicum L.) was carried out to get better efficacy of the drugs. A total of 16 batches (F1-F16) of cream were prepared by adding varying concentrations of hydro-alcoholic extract of the drugs (20%, 40% and 50%) in water removable bases, and three batches were selected as final batches (F4-20%, F6-40% and F16-50%). In vitro antidermatophytic activity was conducted to optimize MIC against dermatophytosis-causing fungi. Dermal irritation of the prepared cream was determined in New Zealand Albino Rabbits. In vivo testing of the different concentrations of the prepared cream (20%, 40%, and 50%) was also carried out using Wistar rats to assess the antidermatophytic activity. Final batches showed good results in all the tested parameters and significant in vitro and in vivo antifungal activity in a dose-dependent manner. No microbial growth was seen in the prepared formulation. The study revealed significant antidermatophytic activity of the prepared cream against dermatophytosis-causing fungi. Hence, it can be concluded that the prepared cream can be an alternative topical agent with safe and effective antifungal activity for treating dermatophytosis.

The classical dermatophytes diagnosis is based on mycological culture and microscopy observation both human and animal hair, skin, and nail samples. The aim of this work was to develop the new in-house real-time PCR with pan-dematophyte reaction for detection and identification of the main dermatophytes directly from hair samples, providing a simple and rapid diagnosis of dermatophytosis in dogs and cats. An in-house SYBR-Green real-time PCR was designed and used for detecting a DNA fragment encoding chitin synthase 1 (CHS1). A total of 287 samples were processed by culture, microscopic examination with KOH 10%, and real-time PCR (qPCR) analysis. Melting curve analysis of the CHS1 fragment revealed to be reproducible, showing a single distinct peak for each species of dermatophyte, namely Trichophyton mentagrophytes, T. verrucosum, Microsporum canis, and Nannizzia gypsea (formerly M. gypseum). Then, out of the 287 clinically suspected cases of dermatophytosis, 50% were positive for dermatophytes by qPCR, 44% by mycological culture, and 25% by microscopic examination. Microsporum canis was identified in 117 samples tested by culture and 134 samples tested by qPCR, followed by N. gypsea in 5 samples (either tested by culture or qPCR) and T. mentagrophytes detected in 4 and 5 samples when tested by culture or qPCR, respectively. Overall, qPCR allowed the diagnosis of dermatophytosis in clinical samples. The results suggest this newly proposed in-house real-time PCR assay can be used as alternative diagnosis and rapid identification of dermatophytes frequently associated to clinical hair samples of dogs and cats.
The aim of this work was to develop a molecular detection strategy for dermatophytes by SYBR-Green real-time PCR of hair samples from animals. The melting curve analysis of the CHS1 fragment revealed to be reproducible, showing a single distinct peak for distinct dermatophyte species and allowed the diagnosis of dermatophytosis in dogs and cats caused mainly by Trichophyton mentagrophytes, Microsporum sp., and Nannizzia gypsea).

BACKGROUND: There are limited clinical studies evaluating the Trichophyton mentagrophytes complex, with most reports confined to small case studies. Additionally, the studies are dated and provide limited information on response to newer or currently available therapies.
OBJECTIVE: The aim of the study was to determine if there is a breed prevalence, lesion distribution and seasonality associated with the T. mentagrophytes complex for dogs evaluated in the central United States. An additional aim of the study was to evaluate response to therapies because there are minimal data available on clinical response with newer systemic antifungal drugs.
METHODS: A total of 64 canine medical records were evaluated that had a previous diagnosis of T. mentagrophytes complex infection.
METHODS: A retrospective study of medical records to evaluate signalment, time of onset of clinical signs, clinical presentation and therapeutic management.
RESULTS: A higher incidence of T. mentagrophytes complex infection was observed in the American Kennel Club (AKC) Sporting group (43%) and Terrier group (20%). A seasonal influence was noted, with the onset of clinical signs being highest in October. Lesions most often affected the muzzle (48%), followed by the head excluding the pinnae (21%). Ketoconazole, itraconazole and terbinafine appeared equivalent as systemic therapeutic options to treat T. mentagrophytes complex infections.
CONCLUSIONS: This study identified patterns in breeds, seasonality and lesion distribution for the T. mentagrophytes complex in dogs from the central United States. Additionally, the study found several reasonable and reliable treatment options for systemic therapy.
BACKGROUND: Il existe peu d\'études cliniques évaluant le complexe Trichophyton mentagrophytes. En effet, la plupart des rapports se limite à de petites études de cas. De plus, les études sont anciennes et fournissent des informations limitées sur la réponse aux thérapies plus récentes ou disponibles actuellement. HYPOTHÈSE/OBJECTIFS: Le but de l\'étude est de déterminer s\'il existe une prévalence raciale, une distribution des lésions et une saisonnalité associées au complexe T. mentagrophytes chez les chiens examinés dans le centre des États-Unis. Un objectif additionnel est d\'évaluer la réponse aux traitements, car peu de données sont disponibles sur la réponse clinique aux nouveaux antifongiques systémiques.
UNASSIGNED: Un total de 64 dossiers médicaux de chiens atteints antérieurement d\'une infection par le complexe T. mentagrophytes est étudié. MATÉRIELS ET MÉTHODES: Une étude rétrospective des dossiers médicaux est effectuée afin d’évaluer le signalement, le moment d\'apparition des signes cliniques, la présentation clinique et la prise en charge thérapeutique. RÉSULTATS: Une incidence plus élevée d\'infection par le complexe T. mentagrophytes est observée dans le groupe des chiens de sport de l’« American Kennel Club » (AKC ) (43 %) et le groupe Terrier (20 %). Une influence saisonnière a été notée, avec une apparition des signes cliniques plus élevée en octobre. Les lésions atteignent le plus souvent le museau (48 %), suivi de la tête (sauf pavillons) (21 %). Le kétoconazole, l\'itraconazole et la terbinafine semblent constituer des traitements systémiques équivalents pour le traitement des infections du complexe T. mentagrophytes.
UNASSIGNED: Cette étude identifie des tendances raciales, la saisonnalité et la distribution des lésions pour les infections canines associées au complexe T. mentagrophytes dans centre des États-Unis. De plus, l\'étude met en évidence plusieurs options thérapeutiques systémiques raisonnables et fiables.
INTRODUCCIÓN: existen pocos estudios clínicos que evalúan el complejo Trichophyton mentagrophytes, y la mayoría de las publicaciones se limitan a estudios de pocos casos. Además, los estudios son antiguos y proporcionan información limitada sobre la respuesta a las terapias más novedosas actualmente disponibles. HIPÓTESIS/OBJETIVOS: El objetivo del estudio fue determinar si existe una prevalencia de raza, distribución de lesiones y estacionalidad asociadas con el complejo T. mentagrophytes para perros evaluados en el centro de los Estados Unidos. Un objetivo adicional del estudio fue evaluar la respuesta a nuevas terapias porque hay datos mínimos sobre la respuesta clínica con antifúngicos sistémicos más recientes. ANIMALES: Se evaluaron un total de 64 historias clínicas de perros que tenían diagnóstico previo de infección con el complejo T. mentagrophytes. MATERIALES Y MÉTODOS: Estudio retrospectivo de historias clínicas para evaluar la reseña, tiempo de aparición de los signos clínicos, presentación clínica y manejo terapéutico. RESULTADOS: Se observó una mayor incidencia de infección por el complejo T. mentagrophytes en el grupo AKC Sporting (43%) y el grupo Terrier (20%). Se observó una influencia estacional, siendo más alta la aparición de los signos clínicos en octubre. Las lesiones afectaron con mayor frecuencia al hocico (48%), seguido de la cabeza excluyendo los pabellones auriculares (21%). El ketoconazol, el itraconazol y la terbinafina parecían similares como opciones terapéuticas sistémicas para tratar las infecciones complejas por T. mentagrophytes. CONCLUSIONES Y RELEVANCIA CLÍNICA: este estudio identificó parámetros de distribución en razas, estacionalidad y localización de lesiones para el complejo T. mentagrophytes en perros del centro de los Estados Unidos. Además, el estudio encontró varias opciones de tratamiento razonables y de confianza para la terapia sistémica.
UNASSIGNED: Es gibt nur wenige Studien, die den Trichophyton mentagrophytes Komplex evaluieren, wobei die meisten Berichte auf kleine Studien beschränkt sind. Außerdem sind diese Studien alt und liefern nur eine geringe Information über die Reaktion auf neuere oder zurzeit verfügbare Therapien.
UNASSIGNED: Das Ziel dieser Studie war es, eine Rassenprävalenz, ein Verteilungsmuster der Veränderungen und eine Saisonalität im Zusammenhang mit dem T. mentagrophytes Komplex bei Hunden, die in den zentralen Vereinigten Staaten evaluiert wurden, festzustellen. Ein zusätzliches Ziel dieser Studie war eine Evaluierung der Reaktion auf Therapien, da nur minimale Daten über die klinische Antwort bei neueren systemischen Antimykotika existieren.
UNASSIGNED: Insgesamt wurden 64 medizinische Krankenakten evaluiert, bei denen die vorhergehende Diagnose einer T. mentagrophytes Komplex Infektion bestand.
UNASSIGNED: Eine retrospektive Studie der medizinischen Karteien wurde durchgeführt, wobei das Signalement, die Zeit der ersten klinischen Anzeichen, die klinische Präsentation und das therapeutische Management betrachtet wurden.
UNASSIGNED: Es wurde eine höhere T. mentagrophytes Komplex Infektion in der AKC Sporthundegruppe (43%) und der Terriergruppe (20%) beobachtet. Es wurde ein saisonaler Einfluss festgestellt, wobei das Auftreten der klinischen Zeichen im Oktober am höchsten war. Die Hautveränderungen betrafen am häufigsten die Nase (48%), gefolgt von Kopf (21%), wobei die Ohren nicht betroffen waren. Ketokonazol, Itrakonazol und Terbinafin schienen gleichwertige systemische Optionen darzustellen, um T. mentagrophytes Komplex Infektionen zu behandeln.
UNASSIGNED: Diese Studie identifizierte Verteilungsmuster bei Rassen, eine Saisonalität und eine Verteilung der Veränderungen für den T. mentagrophytes Komplex bei Hunden in den zentralen Staaten der United States. Zusätzlich ergab die Studie mehrere vernünftige und verlässliche Behandlungsoptionen für eine systemische Therapie.
要約 背景: Trichophyton mentagrophytes complexを評価する臨床研究は限られており、ほとんどの報告は小規模なケーススタディにとどまっている。また、これらの研究は古く、新しい治療法や現在利用可能な治療法に対する反応については限られた情報しか提供されていない。 仮説/目的: 本研究の目的は，米国中央部で評価された犬について、T. mentagrophytes complexに関連する犬種の有病率、病変の分布、季節性があるかどうかを調べることであった。また、新しい全身性抗真菌薬の臨床効果に関するデータが少ないため、治療に対する反応を評価することも研究の目的とした。 対象動物: T. mentagrophytes complex感染症の診断を受けたことのある犬64頭のカルテを評価した。 材料と方法: 診療録から、シグナル、臨床症状発現時期、臨床症状、治療管理についてレトロスペクティブに評価した。 結果: T. mentagrophytes complex感染の発症率は、アメリカンケネルクラブにおけるスポーティング・グループ(43%)およびテリア・グループ(20%)で高頻度に観察された。季節的な影響も認められ、臨床症状の発現は10月に最も高かった。病変はマズルが最も多く(48%)、次いで耳介を除く頭部(21%)であった。T. mentagrophytes complex感染に対する全身療法の反応は、ケトコナゾール、イトラコナゾール、テルビナフィンで同等であった。 結論と臨床的関連性: 本研究では、米国中央部の犬におけるT. mentagrophytes complexの品種、季節、病変の分布のパターンを明らかにした。さらに、本研究では、全身療法として合理的で信頼性の高い治療法をいくつか見出した。.
背景: 评价须毛癣菌复合种的临床研究有限，大多数报告仅限于小规模病例研究。此外，这些研究是过时的，而新的或目前可用疗法反应的新信息有限。 假设/目的: 这项研究的目的是评估确定美国中部须毛毛癣菌复合体的犬种流行率、病变分布和季节性。这项研究的另一个目的是评估治疗反应，因为关于新型全身性抗真菌药物的临床反应数据很少。 动物: 共评估了64份犬病历，这些病例之前曾被诊断为须毛癣菌复合种感染。 材料和方法: 对病历进行回顾性研究，以评估病征、临床症状发作时间、临床表现和治疗管理。 结果: AKC 运动犬组(43%)和㹴类组(20%)的须毛癣菌复合种感染发生率较高。存在季节性影响，临床症状在10月份发病率最高。病变最常发生在口鼻部(48%)，其次是头部，不包括耳廓(21%)。酮康唑、伊曲康唑和特比萘芬应该可以作为全身治疗须毛癣菌复合种感染的选择。 结论和临床相关性: 这项研究确定了美国中部须毛癣菌复合种的犬种、季节性和病变分布模式。此外，该研究还发现了几种合理可靠的全身性治疗方案。.
Resumo CONTEXTO: São limitados os estudos clínicos avaliando o complexo Trichophyton mentagrophytes, sendo a maioria deles estudos com poucos casos. Além disto, os estudos são antigos e fornecem informações limitadas sobre a resposta a tratamentos novos ou disponíveis atualmente. HIPÓTESE/OBJETIVOS: O objetivo deste estudo foi determinar se há predisposição racial, distribuição lesional e sazonalidade associadas ao complexo T. mentagrophytes em cães avaliados na região central dos Estados Unidos. O objetivo adicional deste estudo foi avaliar a resposta terapêutica, pois são poucos os estudos disponíveis sobre a resposta clínica a novos antifúngicos sistêmicos. ANIMAIS: Um total de 64 prontuários de cães diagnosticados com infecção por pelo complexo T. mentagrophytes foram avaliados. RESULTADOS: Observou-se uma maior incidência de infecção pelo complexo T. mentagrophytes no grupo de cães de esporte do AKC (43%) e no grupo Terrier (20%). Foi observada uma influência sazonal, com o início dos sinais clínicos principalmente em outubro. As lesões afetavam principalmente o focinho (48%), seguido pela cabeça excluindo as orelhas (21%). Cetoconazol, itraconazol e terbinafina foram aparentemente equivalentes como opções terapêuticas sistêmicas para tratar infecções pelo complexo T. mentagrophytes. CONCLUSÔES E RELEVÂNCIA CLÍNICA: Este estudo identificou padrões nas raças, sazonalidade e distribuição lesional para o complexo T. mentagrophytes em cães da região central dos Estados Unidos. Além disto, o estudo encontrou diversos tratamentos adequados e confiáveis para a terapia sistêmica.