primary closure

初级闭合
  • 文章类型: Case Reports
    我们报告了一例通过腹外缝合进行初次闭合修复的Morgagni疝。此外,我们回顾了腹腔镜修复的Morgagni疝病例,已知疝气缺损的大小,建立网格利用率的尺寸标准。一名87岁的妇女因右上腹部疼痛和呕吐来到我们医院。她没有腹部手术或外伤史。胸部X线摄影和计算机断层扫描(CT)显示Morgagni疝,胃和横结肠突出进入右胸腔。最初,由于她的年龄,对胃疝进行了内窥镜修复,这是成功的。然而,两天后她复发了,促使我们进行半紧急腹腔镜手术。腹腔镜检查显示有Morgagni缺陷,用网膜,横结肠,胃突出,胃因气腹而缩小。幸运的是,突出的器官可以很容易地重新定位到腹部,没有粘连。疝缺损测量为6x3厘米。我们用腹外缝合进行了初次闭合。未进行囊切除。手术持续98分钟。术后第1天开始口服,患者于术后第3天出院,无并发症。术后1个月胸部X线和CT扫描显示无复发,在9个月的随访检查中,患者仍无症状。根据我们的审查结果,原发性闭合是治疗小疝缺损的有效方法(经验法则:宽度,<4厘米;长度,<7厘米)。
    We report a case of a Morgagni hernia repaired by primary closure with an extra-abdominal suture. Moreover, we reviewed cases of laparoscopically repaired Morgagni hernia, in which the size of the hernia defect was known, to establish a size criterion for mesh utilization. An 87-year-old woman presented to our hospital with right upper abdominal pain and vomiting. She had no history of abdominal surgery or trauma. Chest radiography and computed tomography (CT) revealed a Morgagni hernia, with the stomach and transverse colon herniated into the right chest cavity. Initially, an endoscopic repair was performed for the herniated stomach due to her age, which was successful. However, she had a recurrence 2 days later, prompting us to perform a semi-emergent laparoscopic surgery. Laparoscopic examination revealed a Morgagni defect, with the omentum, transverse colon, and stomach herniated, with the stomach reduced by pneumoperitoneum. Fortunately, the herniated organs could be easily relocated into the abdomen with no adhesions. The hernia defect measured 6 x 3 cm. We performed primary closure with an extra-abdominal suture. No sac resection was performed. The operation lasted 98 min. Oral intake was initiated on postoperative day 1, and the patient was discharged on postoperative day 3 without complications. Chest radiography and CT scans at 1 month postoperatively showed no recurrence, and the patient remained asymptomatic at the 9-month follow-up examination. According to our review findings, primary closure is an efficient method for small hernia defects (rule of thumb: width, <4 cm; length, <7 cm).
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  • 文章类型: Journal Article
    背景:这项研究比较了患者报告的功能和美学结果,即对radial骨前臂游离皮瓣(RFFF)供体部位的分裂厚度皮肤移植(STSG)和斧头皮瓣闭合。
    方法:对RFFF(2015-2020)患者进行回顾性分析。那些愿意参加患者报告结果(PRO)的人填写了患者-观察者疤痕评估量表(POSAS)和密歇根手结果问卷(MHOQ)。
    结果:198例患者符合我们的纳入标准,81例患者参加了PRO。STSG与斧头瓣的肌腱暴露率较高(11vs.1,p=0.0019),但皮肤坏死率较低(5vs.16,p=0.0190)和表皮溶解(1vs.12,p=0.0028)。在POSAS的所有领域中,STSG的疤痕质量均优于斧头瓣。两组MHOQ评分相似,总分无统计学差异(p=0.2165)。
    结论:STSG在日常生活活动中似乎不太妥协,更好的满意度和改进的疤痕质量比斧头皮瓣,但肌腱暴露率较高。
    方法:3喉镜,2024.
    BACKGROUND: This study compares patient-reported functional and aesthetic outcomes of split-thickness skin graft (STSG) versus hatchet flap closure of radial forearm free flap (RFFF) donor site.
    METHODS: Patients with RFFF (2015-2020) were retrospectively identified. Those willing to participate in patient-reported outcomes (PRO) filled out Patient-Observer Scar Assessment Scale (POSAS) and Michigan Hand Outcome Questionnaire (MHOQ).
    RESULTS: 198 patients met our inclusion criteria and 81 participated in PRO. There was a higher rate of tendon exposure in STSG versus hatchet flap (11 vs. 1, p = 0.0019), but a lower rate of skin necrosis (5 vs. 16, p = 0.0190) and epidermolysis (1 vs. 12, p = 0.0028). Scar quality in STSG was superior to hatchet flap in all domains of POSAS. MHOQ scores were similar between both groups with no statistical difference in overall scores (p = 0.2165).
    CONCLUSIONS: STSG appeared to have less compromise in activities of daily living, better satisfaction and improved scar quality than hatchet flap, but a higher rate of tendon exposure.
    METHODS: 3 Laryngoscope, 2024.
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  • 文章类型: Meta-Analysis
    本研究旨在探讨二级和一级闭合方法对下颌骨去除后面部伤口疼痛和肿胀程度的影响。出于本研究的目的,三个数据集,包括PubMed和Embase,被选中。对试验的选择进行了单独的统计分析,数据的收集和偏差的风险。用卡方方法分析了试验之间的差异,数据分析依赖于I2。进行了敏感性分析,并评估了可能的发表偏倚。最终,在根据资格和排除标准进行深入评估后,从1922年相关试验的原始池中选择了9项合格试验,以及后续筛查。结果表明,在一次或二次关闭治疗之间,手术后1天的术后疼痛程度没有统计学上的显着变化(MD,-0.46;95%CI,-0.93,0.01,p=0.06);结果表明,两组术后3天后伤口疼痛无统计学差异(MD,-0.15;95%CI,-0.68,0.37,p=0.56);结果表明,两组术后第7天对术后伤口疼痛无统计学差异(MD,-0.14;95%CI,-0.31,0.03,p=0.1)。结果显示,两组术后1天对创面疼痛无统计学差异(MD,-0.26;95%CI,-0.38,-0.13,p<0.0001);手术后第3天,与第一阶段封闭组相比,二次封闭组的面部肿胀明显较小(MD,-0.70;95%CI,-1.40,-0.00,p=0.05)。而对下颌骨手术患者术后伤口疼痛无明显影响,术后面部肿胀有显著性差异。研究结果不支持对这些方法中的任何一种的偏好。
    This research is intended to explore the influence of second and first degree closure methods on the degree of wound pain and swelling of the face following the removal of the mandible. For the purpose of this study, three data sets, including PubMed and Embase, were selected. A separate statistical analysis was conducted on the choice of the trial, the collection of data and the risk of bias. Differences between trials were analysed with a chi-square approach, with data analyses dependent on I2. A sensitivity analysis was conducted, and a possible publication bias was evaluated. Ultimately, nine qualifying trials were chosen out of an original pool of 1922 related trials following an in-depth evaluation under the eligibility and exclusion criteria, as well as a follow-up screening. The results indicated that there was no statistically significant change in the degree of post-operation pain after 1 day operation between one or secondary closures of treatment (MD, -0.46; 95% CI, -0.93, 0.01, p = 0.06); the results showed that there were no statistically significant differences in post-operation wound pain after 3 days in two group (MD, -0.15; 95% CI, -0.68, 0.37, p = 0.56); the results showed that there were no statistically different effects on the post-operation wound pain after the 7th day in two groups (MD, -0.14; 95% CI, -0.31, 0.03, p = 0.1). The results showed that there were no statistically different effects on the post-operation wound pain after the 1 day in two groups (MD, -0.26; 95% CI, -0.38, -0.13, p < 0.0001); on the 3rd day after surgery, the face was significantly smaller swelling in the secondary closure of closure compared with the first-stage closure group (MD, -0.70; 95% CI, -1.40, -0.00, p = 0.05). While there is no obvious effect on post-operation wound pain in patients with mandibular surgery, there is significant difference in post-operation face swelling. The findings do not support a preference for any of these methods.
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  • 文章类型: Randomized Controlled Trial
    <b>br>简介:</b>切口感染是开腹阑尾切除术后最常见的术后并发症。各种研究比较了伤口初次闭合(PC)和延迟初次闭合(DPC)中浅表手术部位感染(SSI)的风险。然而,关于伤口闭合的方法没有统一的共识。</br><b>br>目的:</b>本研究的目的是比较两种伤口闭合技术。</br><b><br>材料和方法:</b>这是一项前瞻性研究,纳入了50名接受开腹阑尾切除术的患者。病人的人口统计学,特点,并记录手术结果。包括年龄超过18岁并进行了右下腹切口阑尾切除术的患者。有任何合并症的患者,病态肥胖,或怀孕被排除在外。患者随机接受两种伤口闭合技术:PC和DPC。在1周和1个月的随访期间,SSI,术后疼痛,比较两组的LOS和LOS。临床评估包括疼痛的视觉模拟量表(1-10)。</br><b><br>结果:</b>在我们的研究中,DPC组的SSI发生率明显低于PC组(p=0.0002),而两组术后疼痛和LOS无显著差异.</br><b><br>结论:</b>我们得出的结论是DPC在降低浅表SSI发生率方面优于PC,但是关于术后疼痛和LOS,两种伤口闭合技术没有不同。</br>.
    <b><br>Introduction:</b> Wound infection is the most common post-operative complication encountered after open appendectomy. Various studies have compared the risk of superficial surgical site infection (SSI) in primary closure (PC) and delayed primary closure (DPC) of wounds. However, there is no uniform consensus regarding the method of wound closure.</br> <b><br>Aim:</b> The aim of this study is to compare the two wound closure techniques.</br> <b><br>Material and methods:</b> This is a prospective study which enrolled 50 patients who underwent open appendectomy. The patients\' demographics, characteristics, and operative findings were recorded. Those who were older than 18 years and had an appendectomy with a right lower quadrant incision were included. Patients with any comorbidity, morbid obesity, or pregnancy were excluded. Patients were randomized to undergo two techniques of wound closure: PC and DPC. During follow- -up at 1 week and 1 month, SSI, post-op pain, and LOS were compared among the two groups. Clinical assessment included the Visual Analog Scale (1-10) for pain.</br> <b><br>Results:</b> In our study, the incidence of SSI in the DPC group was significantly lower than in the PC group (p = 0.0002), while post-op pain and LOS were not significantly different between the two groups.</br> <b><br>Conclusions:</b> We concluded that DPC was superior to PC in terms of reducing the incidence of superficial SSI, but with respect to post-op pain and LOS, the two techniques of wound closure were not different.</br>.
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  • 文章类型: Journal Article
    全喉切除术后的缺损重建已采用了几种技术,其中包括滑动会厌成形术。由于全喉切除术后滑动会厌成形术的数据很少,这项研究旨在通过对患者的回顾性分析来详细介绍这种重建技术。
    我们回顾性回顾了2007-2013年间全喉切除术后咽部重建术患者的单中心医疗记录,随访至2020年。该研究包括进行全喉切除术,然后进行初次闭合或滑动会厌成形术的患者。根据咽部重建技术将患者分为:滑动性会厌炎(n=38)和初次闭合(n=120)。
    患者的基线特征,TNM阶段,和以往的治疗策略在滑动式会厌和初次闭合组之间没有显著差异.术后并发症发生率,包括咽部瘘的形成和狭窄在分析组之间具有可比性;然而,在滑动会厌成形术后的患者中,咽部瘘的发生率略高。接受会厌成形术和初次闭合组的患者的3年总生存率为73.7%。57.5%,分别。
    滑动会厌成形术被认为是一种安全的重建技术。尽管在会厌成形术组中观察到略好的结果,它仍然被认为不如初级闭合。这种技术应该在精心挑选的患者中考虑,在这些患者中,初次闭合是不可行的。带有附近结构的会厌免于疾病,当远端皮瓣不太合适或禁忌时。
    UNASSIGNED: Several techniques have been employed for defect reconstruction after total laryngectomy, among others sliding epiglottoplasty. As there is a paucity of data on sliding epiglottoplasty after total laryngectomy, this study aimed to present this reconstruction technique in detail with the retrospective analysis of the patients.
    UNASSIGNED: We retrospectively reviewed single-center medical records of patients who underwent pharyngeal reconstruction after total laryngectomy between 2007-2013, with a follow-up to 2020. The study included patients who had total laryngectomy performed followed by a primary closure or sliding epiglottoplasty. The patients were divided according to the pharyngeal reconstruction technique: sliding epiglottis (n = 38) and primary closure (n = 120).
    UNASSIGNED: The baseline characteristics of patients, TNM stages, and previous treatment strategies did not differ significantly between the sliding epiglottis and primary closure group. The postoperative complication rates, including the pharyngocutaneous fistulae formation and strictures were comparable between the analyzed groups; however, a slightly higher incidence of pharyngocutaneus fistulae was noted within the patients after sliding epiglottoplasty. Overall 3-year survival of patients who underwent the epiglottoplasty and primary closure group were 73.7% vs. 57.5%, respectively.
    UNASSIGNED: Sliding epiglottoplasty is considered a safe reconstruction technique. Although slightly better outcomes were noted within the epiglottoplasty group, it is still considered inferior to the primary closure. This technique ought to be considered in meticulously selected patients in whom primary closure is not feasible, epiglottis with nearby structures is spared from disease, and when the distal flaps are less appropriate or contraindicated.
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  • 文章类型: Journal Article
    简介由于围手术期败血症的不利影响和患者术前优化的相对缺乏,急诊手术具有很高的并发症风险。尽管脓毒症的重症监护取得了进展,它的预防取决于各种患者和外科医生的因素。手术部位感染仍然是急诊腹部手术后发病率和死亡率的主要决定因素。尤其是受污染或肮脏的伤口。本研究旨在比较两种腹壁闭合技术,负压伤口治疗后,皮下抽吸引流和延迟初次闭合,在手术部位感染和发病率方面。材料和方法该研究是一项前瞻性比较研究,包括50例需要剖腹手术的急腹症患者。患者被随机分为两组,A组(n=25)进行了初次闭合,B组(n=25)接受延迟初次闭合。B组患者中,在皮肤闭合之前,在皮下空间中应用真空辅助闭合装置5天。结果比较了浅表和深部手术部位感染的发生率,它与糖尿病的关系,以及总住院时间。卡方检验和非配对t检验用于显著性检验。结果共50例患者,年龄相当,包括在研究中。与B组相比,A组患者手术部位感染的总发生率明显更高(p=0.0046)。两组糖尿病与伤口感染的发生呈正相关,比值比分别为2.67和2.38。与B组相比,A组浅表伤口感染的发生率明显更高(52%对24%;p=0.04)。A组患者的深部手术部位感染较高(20%对8%),但无统计学意义(p=0.22)。A组和B组出现并发症的患者平均住院时间分别为41.56±6.96和37.86±6.68天,而A组和B组的无并发症病例则低了近两倍半(分别为11.71±1.70天和16.58±1.06天)。单尾非配对t检验显示,有并发症和无并发症患者的住院时间差异显着(T:17.06,临界值:1.677)。结论延迟一期闭合是急诊剖腹手术后处理污染和脏污伤口的有效方法。负压伤口治疗是一种在这种情况下预防伤口床感染和加速伤口愈合的技术。通过在紧急手术中结合上述内容,手术部位感染的发生率和住院时间可显著减少。
    Introduction Emergency surgery has a high risk of complications due to the detrimental effect of perioperative sepsis and the relative lack of preoperative optimization of patients. Despite advances in critical care for the management of sepsis, its prevention is dependent on various patient and surgeon factors. Surgical site infection continues to be a major determinant of morbidity and mortality following emergency abdominal surgery, especially in contaminated or dirty wounds. This study aims to compare two techniques of abdominal wall closure, primary closure with subcutaneous suction drains and delayed primary closure following negative pressure wound therapy, in terms of incidence of surgical site infection and morbidity. Materials and methods The study was a prospective comparative study including 50 patients with an acute surgical abdomen requiring laparotomy. The patients were randomized into two groups, Group A (n=25) who underwent primary closure, and Group B (n=25) who underwent delayed primary closure. In Group B patients, a vacuum-assisted closure device was applied in the subcutaneous space for five days prior to the closure of the skin. Outcomes were compared in terms of the incidence of superficial and deep surgical site infection, its association with diabetes mellitus, and the total duration of hospital stay. A chi-square test and an unpaired t-test were used for the test of significance. Results A total of 50 patients, comparable in age, were included in the study. The overall incidence of surgical site infection was significantly higher in patients of Group A as compared to Group B (p=0.0046). There was a positive correlation between diabetes mellitus and the occurrence of wound infection in both groups with the odds ratio being 2.67 and 2.38 respectively. The incidence of superficial wound infection was significantly higher in Group A when compared to Group B (52% versus 24%; p=0.04). Deep surgical site infection was higher in patients of Group A (20% versus 8%) but was not statistically significant (p=0.22). The average duration of hospital stay was 41.56 ± 6.96 and 37.86 ± 6.68 days for patients who developed complications from Groups A and B respectively, while it was nearly two and a half times lower in uncomplicated cases of Groups A and B (11.71± 1.70 days and 16.58± 1.06 days respectively). The one-tailed unpaired t-test showed a significant difference in means of hospital stay between patients with and without complications (T: 17.06, critical value: 1.677). Conclusion Delayed primary closure is an effective method of managing contaminated and dirty wounds following emergency laparotomy. Negative pressure wound therapy is one technique for preventing wound bed infection and accelerating wound healing in such cases. By combining the above in emergency surgeries, the incidence of surgical site infection and duration of hospital stay can be significantly reduced.
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  • 文章类型: Case Reports
    一般来说,如果唇癌缺损的大小超过下唇的30%,建议使用局部皮瓣或自由皮瓣。然而,在没有局部皮瓣或游离皮瓣的情况下,通过初次闭合已成功重建了下唇50%的缺损。在一个案例中,一名吸烟超过50年的80岁男性农民出现下唇鳞状细胞癌,并接受了大量切除和舌骨上颈部清扫术。缺损几乎占下唇的2/3,并通过V形切除的初次闭合修复。活检结果证实pT2N0cM0II期疾病,边缘清晰。在另一种情况下,一名68岁男性也出现了下唇鳞状细胞癌,并接受了肿块切除术。缺损约占下唇大小的一半,但通过V形切除的初次闭合修复。两名患者在进食或说话时没有出现不适,并且对美容和功能结果感到满意,没有复发的证据。因此,即使在下唇癌中也可以考虑直接闭合。
    Generally, if the size of a lip cancer defect exceeds 30% of the lower lip, a local flap or free flap is recommended. However, defects up to 50% of the lower lip in size have been reconstructed successfully by primary closure without a local flap or free flap. In one case, an 80-year-old male farmer who had smoked for more than 50 years presented with squamous cell carcinoma of the lower lip and underwent mass resection and supraomohyoid neck dissection. The defect accounted for almost 2/3 of the lower lip and was repaired by primary closure with V-shaped resection. Biopsy results confirmed pT2N0cM0 stage II disease with clear margins. In another case, a 68-year-old male also presented with squamous cell carcinoma of the lower lip and underwent mass resection. The defect accounted for about half the size of the lower lip but was repaired by primary closure with V-shaped resection. Both patients experienced no discomfort while eating or speaking and were satisfied with the cosmetic and functional outcomes with no evidence of recurrence. Thus, direct closure can be considered even in large lower lip cancers.
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  • 文章类型: Randomized Controlled Trial
    背景:回肠造口术后圆形皮肤伤口的周向表皮下伤口逼近(CSWA)被认为可降低手术部位感染率(SSI)。我们进行了这项随机试验,以比较原发性线性皮肤闭合(PC)和CSWA组患者的SSI率和其他短期结局。患者和方法:在研究期间接受回肠造口术逆转的所有患者被随机分配到PC或CSWA。主要结果是通过ASEPSIS评分系统评估的SSI发生率。次要结果包括愈合时间,术后住院时间,和患者对美容结果的满意度,期望,疼痛,愈合的时间,伤口护理,和五点李克特量表的活动。结果:31例患者(PC=15;CSWA=16)在研究期间接受了回肠造口术逆转。PC组没有SSI,而CSWA组有3名患者发生SSI,但结果无统计学意义(p=0.23)。愈合时间评分(p<0.001),伤口护理(p=0.007),与CSWA相比,PC的活性(p<0.001)明显更好,而美容结果的评分没有显着差异,期望,和痛苦。PC组愈合时间较短(6.7vs.34.2天;p<0.001),而术后住院时间相当(6.3vs.7天;p=0.27)。结论:虽然两组患者的SSI发生率无差异,PC组在平均愈合时间和伤口护理需求方面表现更好。
    Background: Circumferential subcuticular wound approximation (CSWA) of round shaped skin wounds after ileostomy take down is believed to lower the rates of surgical site infection (SSI). We performed this randomized trial to compare the rates of SSI and other short-term outcomes among primary linear skin closure (PC) and CSWA groups of patients. Patients and Methods: All patients undergoing ileostomy reversal during the study period were randomly assigned to either PC or CSWA. The primary outcome was the incidence of SSI as assessed by ASEPSIS scoring system. The secondary outcomes included healing time, length of post-operative hospital stay, and patients\' satisfaction regarding cosmetic outcome, expectations, pain, time of healing, wound care, and activity on a five-point Likert scale. Results: Thirty-one patients (PC = 15; CSWA = 16) underwent ileostomy reversal during the study period. There was no SSI in the PC group whereas three patients developed SSI in the CSWA group but the result was not statistically significant (p = 0.23). The scores for time of healing (p < 0.001), wound care (p = 0.007), and activity (p < 0.001) were significantly better for PC compared with CSWA whereas there was no significant difference in the scores for cosmetic outcome, expectations, and pain. Healing time was shorter in the PC group (6.7 vs. 34.2 days; p < 0.001) whereas the post-operative length of stay was comparable (6.3 vs. 7 days; p = 0.27). Conclusions: Although there was no difference in the incidence of SSI among the two groups, the PC group fared better in terms of mean time to healing and requirement of wound care.
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  • 文章类型: Journal Article
    背景:根据目前胆总管结石发病率上升的趋势,探讨腹腔镜胆总管切开取石术中胆总管的闭合方法具有重要意义。
    方法:选择回溯全层连续外翻缝线初次闭合胆总管缝线,对照组采用传统T管引流。倾向评分匹配(PSM)用于减少两组之间的基线差异。
    结果:术中失血,操作时间,术后恢复速度,术后出血,术后胰腺炎,胆管结石的复发率,初次封闭组的住院时间均少于T管引流组。
    结论:在一定条件下,与传统T管引流相比,回溯全厚度连续外翻缝合术可使胆总管结石患者受益.
    BACKGROUND: Based on the current trend of increasing incidence of choledocholithiasis, it is of great significance to explore the closure method of the common bile duct during laparoscopic choledocholithotomy.
    METHODS: Backtracking full-thickness continuous everting suture was selected for primary closure of the common bile duct suture, while traditional T-tube drainage was selected for the control group. Propensity score matching (PSM) was used to reduce baseline differences between the two groups.
    RESULTS: The intraoperative blood loss, operation time, postoperative recovery speed, postoperative bleeding, postoperative pancreatitis, recurrence rate of bile duct stones, and hospitalization time in the primary closure group were all less than those in the T-tube drainage group.
    CONCLUSIONS: Under certain conditions, backtracking full-thickness continuous everting suture could benefit patients with choledocholithiasis compared with traditional T-tube drainage.
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  • 文章类型: Journal Article
    目的:回顾不使用截骨或下肢/骨盆固定的经典膀胱外翻封闭的结果。
    方法:回顾了一个前瞻性维护的机构批准的外翻-外翻复杂数据库,该数据库包含1487例患者,这些患者在没有截骨或固定的情况下进行了闭合的CBE患者。所有患者均被转诊至作者机构,以便在以后的生活中进行重建或关闭失败。
    结果:在总共1016例CBE患者中,确定了56例闭合事件,共纳入47例独特患者。在1990年之前完成了38个关闭(67.9%)。45个闭合事件最终失败(45/56,80.4%)(表1)。13例闭合事件为二次闭合(13/56,23.2%)。一次闭合失败率为83.7%(36/43),二次闭合失败率为69.2%(9/13)。失败归因于一种或多种:开裂,膀胱脱垂,膀胱皮肤瘘(25/45,55.6%)(23/45,51.1%)(6/45,13.3%)。37例患者出现社交节制(37/47,78.7%),而只有8例患者出现自发性尿失禁(7/47,17.0%)(表2)。最常见的排尿方法是大陆的可导管通道(25/47,53.2%),其中全部是社会大陆。
    结论:这些结果说明了截骨和术后固定在原发性和继发性外翻闭合中的关键作用。虽然这是一个历史案例系列,作者认为,这些结果仍然与当代exstrophy外科医生相关。
    To review the outcomes of classic bladder exstrophy (CBE) closure without the use of osteotomy or lower extremity/pelvic immobilization.
    A prospectively maintained institutional approved exstrophy-epispadias complex database of 1487 patients was reviewed for patients with CBE who had undergone closure without osteotomy nor immobilization. All patients were referred to the authors\' institution for reconstruction later in life or for failed closure.
    Of a total of 1016 CBE patients, 56 closure events were identified that met inclusion with a total of 47 unique patients. Thirty-eight closures were completed prior to 1990 (67.9%). Forty-five closure events developed eventual failure (45/56, 80.4%) (Table 1). Thirteen closure events were secondary closures (13/56, 23.2%). The primary closure failure rate was 83.7% (36/43) while the secondary closure failure rate was 69.2% (9/13). Failures were attributed to one or more of dehiscence, bladder prolapse, and vesicocutaneous fistula (25/45, 55.6%) (23/45, 51.1%) (6/45, 13.3%), respectively. Thirty-seven patients developed social continence (37/47, 78.7%), while only 8 patients developed spontaneous voided continence (7/47,17.0%) (Table 2). The most common methods of voiding were continent catheterizable channels (25/47, 53.2%) of which all were socially continent.
    These results illustrate the critical role osteotomy and postoperative immobilization can play in both primary and secondary exstrophy closure. While this is a historical case series, the authors believe that these results remain relevant to contemporary exstrophy surgeons.
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