关键词: defect reconstruction epiglottoplasty neopharynx primary closure total laryngectomy

来  源:   DOI:10.3389/fonc.2023.1284266   PDF(Pubmed)

Abstract:
UNASSIGNED: Several techniques have been employed for defect reconstruction after total laryngectomy, among others sliding epiglottoplasty. As there is a paucity of data on sliding epiglottoplasty after total laryngectomy, this study aimed to present this reconstruction technique in detail with the retrospective analysis of the patients.
UNASSIGNED: We retrospectively reviewed single-center medical records of patients who underwent pharyngeal reconstruction after total laryngectomy between 2007-2013, with a follow-up to 2020. The study included patients who had total laryngectomy performed followed by a primary closure or sliding epiglottoplasty. The patients were divided according to the pharyngeal reconstruction technique: sliding epiglottis (n = 38) and primary closure (n = 120).
UNASSIGNED: The baseline characteristics of patients, TNM stages, and previous treatment strategies did not differ significantly between the sliding epiglottis and primary closure group. The postoperative complication rates, including the pharyngocutaneous fistulae formation and strictures were comparable between the analyzed groups; however, a slightly higher incidence of pharyngocutaneus fistulae was noted within the patients after sliding epiglottoplasty. Overall 3-year survival of patients who underwent the epiglottoplasty and primary closure group were 73.7% vs. 57.5%, respectively.
UNASSIGNED: Sliding epiglottoplasty is considered a safe reconstruction technique. Although slightly better outcomes were noted within the epiglottoplasty group, it is still considered inferior to the primary closure. This technique ought to be considered in meticulously selected patients in whom primary closure is not feasible, epiglottis with nearby structures is spared from disease, and when the distal flaps are less appropriate or contraindicated.
摘要:
全喉切除术后的缺损重建已采用了几种技术,其中包括滑动会厌成形术。由于全喉切除术后滑动会厌成形术的数据很少,这项研究旨在通过对患者的回顾性分析来详细介绍这种重建技术。
我们回顾性回顾了2007-2013年间全喉切除术后咽部重建术患者的单中心医疗记录,随访至2020年。该研究包括进行全喉切除术,然后进行初次闭合或滑动会厌成形术的患者。根据咽部重建技术将患者分为:滑动性会厌炎(n=38)和初次闭合(n=120)。
患者的基线特征,TNM阶段,和以往的治疗策略在滑动式会厌和初次闭合组之间没有显著差异.术后并发症发生率,包括咽部瘘的形成和狭窄在分析组之间具有可比性;然而,在滑动会厌成形术后的患者中,咽部瘘的发生率略高。接受会厌成形术和初次闭合组的患者的3年总生存率为73.7%。57.5%,分别。
滑动会厌成形术被认为是一种安全的重建技术。尽管在会厌成形术组中观察到略好的结果,它仍然被认为不如初级闭合。这种技术应该在精心挑选的患者中考虑,在这些患者中,初次闭合是不可行的。带有附近结构的会厌免于疾病,当远端皮瓣不太合适或禁忌时。
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