PDF(Pubmed)
Abstract：
This research is intended to explore the influence of second and first degree closure methods on the degree of wound pain and swelling of the face following the removal of the mandible. For the purpose of this study, three data sets, including PubMed and Embase, were selected. A separate statistical analysis was conducted on the choice of the trial, the collection of data and the risk of bias. Differences between trials were analysed with a chi-square approach, with data analyses dependent on I2. A sensitivity analysis was conducted, and a possible publication bias was evaluated. Ultimately, nine qualifying trials were chosen out of an original pool of 1922 related trials following an in-depth evaluation under the eligibility and exclusion criteria, as well as a follow-up screening. The results indicated that there was no statistically significant change in the degree of post-operation pain after 1 day operation between one or secondary closures of treatment (MD, -0.46; 95% CI, -0.93, 0.01, p = 0.06); the results showed that there were no statistically significant differences in post-operation wound pain after 3 days in two group (MD, -0.15; 95% CI, -0.68, 0.37, p = 0.56); the results showed that there were no statistically different effects on the post-operation wound pain after the 7th day in two groups (MD, -0.14; 95% CI, -0.31, 0.03, p = 0.1). The results showed that there were no statistically different effects on the post-operation wound pain after the 1 day in two groups (MD, -0.26; 95% CI, -0.38, -0.13, p < 0.0001); on the 3rd day after surgery, the face was significantly smaller swelling in the secondary closure of closure compared with the first-stage closure group (MD, -0.70; 95% CI, -1.40, -0.00, p = 0.05). While there is no obvious effect on post-operation wound pain in patients with mandibular surgery, there is significant difference in post-operation face swelling. The findings do not support a preference for any of these methods.
摘要：
本研究旨在探讨二级和一级闭合方法对下颌骨去除后面部伤口疼痛和肿胀程度的影响。出于本研究的目的，三个数据集，包括PubMed和Embase,被选中。对试验的选择进行了单独的统计分析,数据的收集和偏差的风险。用卡方方法分析了试验之间的差异，数据分析依赖于I2。进行了敏感性分析，并评估了可能的发表偏倚。最终,在根据资格和排除标准进行深入评估后，从1922年相关试验的原始池中选择了9项合格试验，以及后续筛查。结果表明，在一次或二次关闭治疗之间，手术后1天的术后疼痛程度没有统计学上的显着变化（MD，-0.46；95％CI，-0.93，0.01，p=0.06）；结果表明，两组术后3天后伤口疼痛无统计学差异（MD，-0.15；95％CI，-0.68，0.37，p=0.56）；结果表明，两组术后第7天对术后伤口疼痛无统计学差异（MD，-0.14；95%CI，-0.31，0.03，p=0.1）。结果显示,两组术后1天对创面疼痛无统计学差异(MD,-0.26；95％CI，-0.38，-0.13，p<0.0001）；手术后第3天，与第一阶段封闭组相比，二次封闭组的面部肿胀明显较小（MD，-0.70；95%CI，-1.40，-0.00，p=0.05）。而对下颌骨手术患者术后伤口疼痛无明显影响,术后面部肿胀有显著性差异。研究结果不支持对这些方法中的任何一种的偏好。
