■常见的颅骨病变包括纤维发育不良(FD),骨内脑膜瘤,骨瘤,朗格汉斯细胞组织细胞增生症(LCH),骨内血管瘤,皮样和表皮样囊肿,和恶性肿瘤。手术切除并切除所涉及的颅骨是这些病变的治疗选择。以前,颅骨缺损是用同种异体移植修复的,和同种异体材料已被新的聚醚醚酮(PEEK)材料所取代,它更有抵抗力,生物相容性并且可以3D打印。高分辨率3D打印使用非常精细的挤出机将材料放入精细的层中,以真实地重建患者的解剖学结构,这提供了优越的美容效果。我们的目标是使用PEEK材料的3D打印颅骨成形术进行颅骨切除术和颅骨病变重建以及颅骨缺损重建的术前计划。
■在本系列中,我们描述了11例颅骨病变在同一坐位中使用3D打印PEEK植入物进行切除和重建的病例,该植入物术前使用高分辨率计算机断层扫描技术设计.所有病例均于2021年至2023年在BangabandhuSheikhMujib医科大学神经外科完成。术后随访6个月。
■关于11个案例,六例为FD,3例为骨内脑膜瘤,1例为骨内血管瘤,一个案例是LCH。平均病灶大小12.73~5.77cm。用PEEK材料进行颅骨成形术。轻微并发症保守治疗。血清腺瘤,术后发热,恶心也在其中。
■人类类似骨骼的生物相容性和对物理力的抵抗力导致PEEK的使用更加频繁,可以更好地修复复杂的颅面缺损。尽管有一些限制,PEEK颅骨修补术植入物继续蓬勃发展,并显示出其成为优秀材料的前景。Further,该技术的开发应投入研究和投资。
UNASSIGNED: Common calvarial lesions include fibrous dysplasia (FD), intraosseous meningioma, osteoma, Langerhans cell histiocytosis (LCH), intraosseous hemangioma, dermoid and epidermoid cyst, and malignancy. Surgical removal with removal of the involved skull is the choice of treatment for these lesions. Previously, the skull defect was repaired using allograft, and alloplastic materials have been replaced with newer polyetheretherketone (PEEK) material, which is more resistant, biocompatible, and can be 3-dimension (3D)--printed. High-resolution 3D printing uses very fine extruders to put materials in fine layers to recreate patients\' anatomy authentically, which gives superior cosmetic outcomes. Our objectives were preoperative planning of craniectomy and reconstruction for calvarial lesions and reconstruction of skull defects using 3D-printed cranioplasty with PEEK materials.
UNASSIGNED: In this series, we describe 11 cases in which skull lesions were removed and reconstructed in the same sitting using a 3D-printed PEEK implant designed preoperatively using high-resolution computer tomography. All the cases were done in the neurosurgery department of Bangabandhu Sheikh Mujib Medical University from 2021 to 2023. Patients were followed up for 6 months after surgery.
UNASSIGNED: Regarding 11 cases, six cases were FD, three cases were intraosseous meningioma, one case was intraosseous hemangioma, and one case was LCH. Average lesion size were 12.73-5.77 cm. Cranioplasty was done with PEEK material. Minor complications were treated conservatively. Seroma, postoperative fever, and nausea were among these.
UNASSIGNED: The human bone-like biocompatibility and resistance to physical forces leads to more frequent use of PEEK, which enables to repair of complex craniofacial defects with better cosmesis. Despite some limitations, the PEEK cranioplasty implant continued to thrive and showed its promise to be an excellent material. Further, research and investment should be put into developing the technique.