%0 Case Reports
%T Fibrous dysplasia: A tale of two syndromes.
%A Fourie J
%A Suleman F
%A Lockhat Z
%A Kollapen K
%J SA J Radiol
%V 28
%N 1
%D 2024
%M 38840825
暂无%R 10.4102/sajr.v28i1.2877
%X Fibrous dysplasia (FD) is a rare, non-inherited, congenital bone disorder which may be monostotic or polyostotic. The polyostotic form may rarely present in syndromic forms when associated with extra-skeletal manifestations. Mazabraud syndrome is a rare syndrome consisting of polyostotic FD presenting with intramuscular myxomas. McCune-Albright syndrome is recognised by polyostotic FD, precocious puberty and 'café au lait' spots. This report describes an adult patient with Mazabraud syndrome and a child with McCune-Albright syndrome.<BR><B>UNASSIGNED: </B>Radiographic findings are typical with bowing deformities, sclerotic, lucent or mixed lesions and bony expansion, often with endosteal scalloping. MRI is often non-contributory and may actually mimic a more aggressive process. Early detection and correct diagnosis allow for early preventative treatment and rehabilitation to prevent devastating neurological sequelae and disability.