{Reference Type}: Case Reports
{Title}: Fibrous dysplasia: A tale of two syndromes.
{Author}: Fourie J;Suleman F;Lockhat Z;Kollapen K;
{Journal}: SA J Radiol
{Volume}: 28
{Issue}: 1
{Year}: 2024
暂无{DOI}: 10.4102/sajr.v28i1.2877
{Abstract}: Fibrous dysplasia (FD) is a rare, non-inherited, congenital bone disorder which may be monostotic or polyostotic. The polyostotic form may rarely present in syndromic forms when associated with extra-skeletal manifestations. Mazabraud syndrome is a rare syndrome consisting of polyostotic FD presenting with intramuscular myxomas. McCune-Albright syndrome is recognised by polyostotic FD, precocious puberty and 'café au lait' spots. This report describes an adult patient with Mazabraud syndrome and a child with McCune-Albright syndrome.<BR><B>UNASSIGNED: </B>Radiographic findings are typical with bowing deformities, sclerotic, lucent or mixed lesions and bony expansion, often with endosteal scalloping. MRI is often non-contributory and may actually mimic a more aggressive process. Early detection and correct diagnosis allow for early preventative treatment and rehabilitation to prevent devastating neurological sequelae and disability.