PDF(Pubmed)
Abstract：
BACKGROUND: Benign notochordal cell tumours (BNCTs) represent a rare entity within the spectrum of bone neoplasms, which typically arise in the axial skeleton. Although these tumours are often benign, their diagnosis and management pose significant challenges due to their histological similarity to more aggressive lesions, such as chordomas. Understanding of the clinical behaviour, diagnostic nuances, and optimal management strategies for BNCTs continues to evolve.
METHODS: Benign notochordal cell tumours of the vertebra are usually asymptomatic and identified on imaging and should be distinguished from chordomas, which has a more aggressive clinical course. This report describes a 15-year-old girl with lumbosacral pain and a diagnosis of a benign notochordal cell tumour, which affects a large part of the S1 vertebra in the lumbar spine, highlighting the diagnostic challenges encountered, the role of radiological and histological investigations, and the ultimate determination of the benign nature of the tumour.
CONCLUSIONS: This report highlights the approach taken for the diagnosis of a benign notochordal cell tumour of the vertebra and the importance of excluding differential diagnoses. By exploring the intricacies of this case, we contribute to the growing body of literature surrounding BNCTs, with the aim of improving clinical awareness and management strategies for this uncommon bone tumour.
METHODS: Benign notochordal cell tumours of the vertebra are usually asymptomatic and identified on imaging and should be distinguished from chordomas, which has a more aggressive clinical course. This report describes a 15-year-old girl with lumbosacral pain and a diagnosis of a benign notochordal cell tumour, which affects a large part of the S1 vertebra in the lumbar spine, highlighting the diagnostic challenges encountered, the role of radiological and histological investigations, and the ultimate determination of the benign nature of the tumour.
CONCLUSIONS: This report highlights the approach taken for the diagnosis of a benign notochordal cell tumour of the vertebra and the importance of excluding differential diagnoses. By exploring the intricacies of this case, we contribute to the growing body of literature surrounding BNCTs, with the aim of improving clinical awareness and management strategies for this uncommon bone tumour.
摘要：
背景：良性脊索细胞肿瘤（BNCT）是骨肿瘤范围内的一种罕见实体，通常出现在轴向骨架中。虽然这些肿瘤通常是良性的，由于它们与更具侵袭性的病变的组织学相似性，它们的诊断和管理带来了重大挑战，如脊索瘤。了解临床行为，诊断细微差别，BNCT的最佳管理策略不断发展。
方法：椎骨的良性脊索细胞肿瘤通常无症状，可在影像学上识别，应与脊索瘤区分开来。具有更积极的临床过程。这份报告描述了一名15岁的女孩，患有腰骶部疼痛，诊断为良性脊索细胞瘤，这会影响腰椎的大部分S1椎骨，强调遇到的诊断挑战，放射学和组织学研究的作用，以及肿瘤良性性质的最终决定。
结论：本报告强调了诊断良性脊椎脊索细胞瘤的方法以及排除鉴别诊断的重要性。通过探索这个案子的复杂性，我们为围绕BNCT的越来越多的文献做出了贡献，目的是提高对这种罕见骨肿瘤的临床认识和管理策略。
方法：椎骨的良性脊索细胞肿瘤通常无症状，可在影像学上识别，应与脊索瘤区分开来。具有更积极的临床过程。这份报告描述了一名15岁的女孩，患有腰骶部疼痛，诊断为良性脊索细胞瘤，这会影响腰椎的大部分S1椎骨，强调遇到的诊断挑战，放射学和组织学研究的作用，以及肿瘤良性性质的最终决定。
结论：本报告强调了诊断良性脊椎脊索细胞瘤的方法以及排除鉴别诊断的重要性。通过探索这个案子的复杂性，我们为围绕BNCT的越来越多的文献做出了贡献，目的是提高对这种罕见骨肿瘤的临床认识和管理策略。
