computer tomography

计算机断层扫描
  • 文章类型: Journal Article
    目的:本研究的目的是确定最佳的放射学参数,以评估耳蜗植入手术中的圆窗入路。
    方法:在Szczecin耳鼻喉科接受人工耳蜗植入的患者,在2015年至2022年期间,有资格参加这项研究。根据八个参数(文献中提出的七个)进行放射学评估,并在术中进行可见性临床评估,量表为1至5(1-不可见,5-完全可见)。圆窗生态位(RWN)和圆窗膜(RWM)的可见性评估允许将差异(RWN减去RWM)用作圆窗上方悬垂尺寸的临床评估。
    结果:对52例患者57耳的计算机断层扫描图像进行了圆窗入路分析。研究组包括26名女性和26名男性,年龄从1岁到80岁不等,平均年龄为41岁。在临床评估中,圆窗能见度为5,去除骨悬垂后,69%的患者。在39例(68%)病例中,通过圆窗进入耳蜗,13例(23%)通过圆窗延伸进入,5例(9%)进行了耳蜗造口术。使用文献(Chen_Angle)和我们的建议(RWM_prediction)中的一个参数,发现了与圆窗访问具有统计学意义的序数相关性。从描述圆窗骨悬垂的参数来看,使用文献中的参数(Sarafraz_OH和Mehanna_OH)发现了正相关(使用Kendall秩检验)。
    结论:根据耳道后壁的解剖结构和面神经的位置,描述进入圆窗的放射学测量值最高。
    结论:在未来,使用算法进行计算机断层扫描评估和机器人辅助手术将需要参数来评估圆窗通道,用于手术计划和电极的选择。总结了各种作者提出的参数,允许研究人员评估其在进一步临床实践中的有用性。
    OBJECTIVE: The aim of this study was to determine optimal radiological parameters for assessment of the round window approach in cochlear implantation surgery.
    METHODS: Patients undergoing cochlear implantation at the Department of Otolaryngology in Szczecin, between 2015 and 2022 inclusive, were eligible for the study. Radiological assessments were performed according to eight parameters (seven proposed in the literature) and visibility clinical assessments were made intra-operatively on a scale of 1 to 5 (1 - not visible, 5 - fully visible). Visibility assessments of the round window niche (RWN) and round window membrane (RWM) allowed the difference (RWN minus RWM) to be used as a clinical assessment of the size of the overhang over the round window.
    RESULTS: Computed tomography images of 57 ears from 52 patients were analyzed in terms of round window access. The study group included 26 females and 26 males, ranging in age from 1 year to 80 years, with a median age of 41 years. In clinical assessment, round window visibility was rated as 5, after removal of the bone overhang, in 69% of patients. Cochlear access through the round window was achieved in 39 (68%) cases, extended access through the round window in 13 (23%) cases and cochleostomy was performed in 5 (9%) cases. Statistically significant ordinal correlations with round-window access were found using one parameter from the literature (Chen_Angle) and from our proposal (RWM_prediction). From parameters describing the bone overhang of the round window, positive correlations (using Kendall rank tests) were found using parameters from the literature (Sarafraz_OH and Mehanna_OH).
    CONCLUSIONS: Radiological measurements describing access to the round window which determine the angle based on the anatomy of the posterior wall of the auditory canal and the position of the facial nerve were found to be of the highest value.
    CONCLUSIONS: In the future, the use of algorithms for computed tomography evaluation and robot-assisted surgery will require parameters for assessing round window access, for surgery planning and choice of electrode. The parameters proposed by various authors are summarized, allowing researchers to assess their usefulness in further clinical practice.
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  • 文章类型: Journal Article
    目的:本研究旨在评估胸主动脉腔内修复术(TEVAR)治疗降主动脉夹层后升主动脉的几何结构变化,并确定直径和长度变化的潜在危险因素。
    方法:2009年4月至2021年7月7日,102例急性降主动脉夹层(B型和非A型非B型)患者接受TEVAR治疗,并纳入本分析。计算机断层扫描血管造影扫描被转移到专用的成像软件和详细的主动脉测量(包括长度,直径和面积)在术后进行多平面重建,六个月后,每年。
    结果:65(58%)患者为男性,平均年龄66(±11)岁。四名(4%)患者被诊断为结缔组织疾病。在TEVAR之前,79%的患者平均接受了1.5(±1.2)种不同类别的抗高血压药物治疗。TEVAR和2.7(±1.0)种不同的抗高血压药物后,这一数字上升到98%。长度没有明显变化,直径,横截面积,在TEVAR后3年的随访期间,升主动脉的体积或升主动脉的体积。身高是平均升主动脉直径(p值=-0.013;B=-8.890)和头臂干水平的平均主动脉直径(p值=0.039;B=-14.763)的负预测指标。
    结论:我们的数据表明,在严格的血压药物治疗下,中期随访期间,TEVAR下行胸主动脉的升主动脉没有明显变化。此外,我们没有发现几何参数增加的任何可改变的危险因素.
    OBJECTIVE: This study aimed to assess geometry changes of the ascending aorta after thoracic endovascular aortic repair (TEVAR) for descending aortic dissection and identify potential risk factors for diameter and length change.
    METHODS: Between 04/2009 and 07/2021, 102 patients were treated for acute descending aortic dissections (Type B and non-A non-B) with TEVAR and were included in this analysis. Computed tomography angiographic scans were transferred to a dedicated imaging software and detailed aortic measurements (including length, diameter and area) were taken in multiplanar reconstruction postoperatively, after six months and annually thereafter.
    RESULTS: Sixty-five (58%) patients were male, with a mean age of 66 (±11). Four (4%) patients were diagnosed with a connective tissue disease. Before TEVAR, 79% of our patients were treated with a mean of 1.5 (±1.2) different classes of antihypertensive medications. This number rose to 98% after TEVAR and 2.7 (±1.0) different antihypertensive drugs. There was no significant change in length, diameter, cross-sectional area, or volume of the ascending aorta during the follow-up of 3 years after TEVAR. Body height was a negative predictor for mean ascending aortic diameter (p-value = -0.013; B = -8.890) and mean aortic diameter at the level of the brachiocephalic trunk (p-value = 0.039; B = -14.763).
    CONCLUSIONS: Our data suggests no significant changes in the ascending aorta following TEVAR of the descending thoracic aorta during mid-term follow-up when under stringent blood pressure medication. Additionally, we did not find any modifiable risk factors for geometry parameter increase.
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  • 文章类型: Journal Article
    暂无摘要。
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  • 文章类型: Journal Article
    比较断层合成表现与X线摄影术的区别,以区分可疑轴性脊柱关节炎(SpA)患者的骶髂关节正常或退行性变化。
    射线照相术,对疑似SpA的连续患者在同一天进行了骶髂关节的断层合成和CT检查(29例患者)。检查是回顾性独立阅读的,被两名放射科医生(一名初级和一名高级,和初级学生两次)。使用kappa系数评估观察者之间和观察者之间的一致性。每种成像灵敏度的有效剂量,评估了特异性和准确性,并与作为金标准的CT进行了比较.
    CT检测到15/58个关节伴有骶髂关节炎。成像灵敏度,特异性和准确性为60%,84%和44%,分别,射线照相和87%,断层合成分别为91%和77%。断层合成的平均有效剂量显着低于CT(少5倍),而显着高于放射线照相术(多8倍)。
    对于疑似SpA的患者,断层合成优于X线摄影,辐射暴露比CT少5倍。
    UNASSIGNED: To compare tomosynthesis performance to radiography for the differentiation of sacroiliitis versus normal or degenerative changes in sacroiliac joints in patients with suspected axial spondyloarthritis (SpA).
    UNASSIGNED: Radiography, tomosynthesis and CT of sacroiliac joints (29 patients) were performed on the same day in consecutive patients with suspected SpA. The examinations were retrospectively read independently, blinded by two radiologists (one junior and one senior, and twice by one junior). Interobserver and intraobserver agreement was evaluated using the kappa coefficient. Effective doses for each imaging sensitivity, specificity and accuracy were assessed and compared with CT as gold standard.
    UNASSIGNED: CT detected 15/58 joints with sacroiliitis. The imaging sensitivity, specificity and accuracy were 60%, 84% and 44%, respectively, for radiography and 87%, 91% and 77% for tomosynthesis. The mean effective dose for tomosynthesis was significantly lower than that of CT (5-fold less) and significantly higher than that of radiography (8-fold more).
    UNASSIGNED: Tomosynthesis is superior to radiography for sacroiliitis detection in patients with suspected SpA, with 5-fold less radiation exposure than CT.
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  • 文章类型: Journal Article
    反刍动物的脑脓肿通常由原发感染灶引起,导致受影响动物的预后不良。这凸显了对不同反刍动物物种的脑脓肿进行全面研究的必要性。我们回顾性调查了流行病学的医疗记录,临床,神经影像学,解剖学病理学,和六只反刍动物的细菌学发现(三只山羊,两头母牛,和一只羊)被诊断患有脑脓肿。所有研究的动物都是雌性。冷漠(50%)强迫性行走(33%),面部敏感度下降(33%),压头(33%),缉获量(33%),半乳质精神状态(33%),斜视(33%),单侧失明(33%),和盘旋(33%)是最常见的神经系统症状。白细胞增多和中性粒细胞增多是血液学评估的主要发现。脑脊液(CSF)分析显示主要是高蛋白质和细胞增多症。在三种情况下,使用计算机断层扫描或磁共振成像,能够识别典型的脓肿病变,随后在验尸中得到证实。在大多数情况下,脓肿样品和/或CSF的微生物培养物显示细菌共感染。先进的影像学检查,结合CSF分析,可以帮助诊断,尽管确认通常依赖于死后评估和病原体的隔离。这项研究有助于临床病理方面,神经影像,和家养反刍动物脑脓肿的细菌学诊断。
    Brain abscesses in ruminants often arise from primary infection foci, leading to an unfavorable prognosis for affected animals. This highlights the need for comprehensive studies on brain abscesses across different ruminant species. We retrospectively investigated medical records of epidemiological, clinical, neuroimaging, anatomopathological, and bacteriological findings in six ruminants (three goats, two cows, and one sheep) diagnosed with brain abscesses. All animals studied were female. Apathy (50%), compulsive walking (33%), decreased facial sensitivity (33%), head pressing (33%), seizures (33%), semicomatous mental status (33%), strabismus (33%), unilateral blindness (33%), and circling (33%) represented the most common neurologic signs. Leukocytosis and neutrophilia were the main findings in the hematological evaluation. Cerebrospinal fluid (CSF) analysis revealed predominant hyperproteinorrachia and pleocytosis. In three cases, computed tomography or magnetic resonance imaging were used, enabling the identification of typical abscess lesions, which were subsequently confirmed during postmortem examination. Microbiological culture of the abscess samples and/or CSF revealed bacterial coinfections in most cases. Advanced imaging examinations, combined with CSF analysis, can aid in diagnosis, although confirmation typically relies on postmortem evaluation and isolation of the causative agent. This study contributes to clinicopathological aspects, neuroimages, and bacteriological diagnosis of brain abscesses in domestic ruminants.
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  • 文章类型: Journal Article
    背景:孤立性肺结节的诊断一直是临床研究的难点和重点。尤其是肉芽肿结节(GNs)与分叶和针状征象,容易误诊为恶性肿瘤。因此,在这项研究中,我们利用CT深度学习(DL)模型来区分具有分叶和针状征象的GNs与实性肺腺癌(LADCs),提高术前诊断的准确性。
    方法:对来自3家医疗机构的420例经病理证实的GNs和LADCs患者进行回顾性研究。识别并标记非增强CT(NECT)和静脉对比增强CT(VECT)中的感兴趣区域,并构建了自我监督标签。来自机构1的病例被随机分为训练集(TS)和内部验证集(IVS),来自机构2和3的病例被视为外部验证集(EVS)。使用自监督迁移学习进行训练和验证,并将结果与放射科医生的诊断结果进行比较。
    结果:DL模型在区分GNs和LADC方面取得了良好的性能,IVS中的曲线下面积(AUC)值为0.917、0.876和0.896,NECT中的EVS为0.889、0.879和0.881,VECT,静脉造影增强CT(NEVECT)图像未增强,分别。放射科医生1、2、3和4的AUC为,分别,(IVS)中的0.739、0.783、0.883和0.901,以及EVS中的0.760、0.760、0.841和0.844。
    结论:CTDL模型对术前从实体LADC中分化出具有分叶和毛刺征象的GNs具有重要价值,其预测性能高于放射科医师。
    BACKGROUND: The diagnosis of solitary pulmonary nodules has always been a difficult and important point in clinical research, especially granulomatous nodules (GNs) with lobulation and spiculation signs, which are easily misdiagnosed as malignant tumors. Therefore, in this study, we utilised a CT deep learning (DL) model to distinguish GNs with lobulation and spiculation signs from solid lung adenocarcinomas (LADCs), to improve the diagnostic accuracy of preoperative diagnosis.
    METHODS: 420 patients with pathologically confirmed GNs and LADCs from three medical institutions were retrospectively enrolled. The regions of interest in non-enhanced CT (NECT) and venous contrast-enhanced CT (VECT) were identified and labeled, and self-supervised labels were constructed. Cases from institution 1 were randomly divided into a training set (TS) and an internal validation set (IVS), and cases from institutions 2 and 3 were treated as an external validation set (EVS). Training and validation were performed using self-supervised transfer learning, and the results were compared with the radiologists\' diagnoses.
    RESULTS: The DL model achieved good performance in distinguishing GNs and LADCs, with area under curve (AUC) values of 0.917, 0.876, and 0.896 in the IVS and 0.889, 0.879, and 0.881 in the EVS for NECT, VECT, and non-enhanced with venous contrast-enhanced CT (NEVECT) images, respectively. The AUCs of radiologists 1, 2, 3, and 4 were, respectively, 0.739, 0.783, 0.883, and 0.901 in the (IVS) and 0.760, 0.760, 0.841, and 0.844 in the EVS.
    CONCLUSIONS: A CT DL model showed great value for preoperative differentiation of GNs with lobulation and spiculation signs from solid LADCs, and its predictive performance was higher than that of radiologists.
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  • 文章类型: Journal Article
    确定评估食管鳞状细胞癌(ESCC)预后最敏感的影像学检查方法。
    30例食管鳞状细胞癌(ESCC)患者参加了研究并接受了放化疗(CRT)。根据生存状态将其分为两组:生存组和非生存组。诊断测试用于确定评估预后的最有效的影像学检查方法。
    1.两组之间在指定时间点的食管造影或计算机断层扫描(CT)上显示的肿瘤长度或CT上显示的最大食管壁厚度没有显着差异。2.在第6周治疗结束时,生存组扩散加权成像(DWI)的肿瘤长度明显低于非生存组(P=0.001)。ROC曲线下面积为0.840(P=0.002),诊断效率中等准确。3.生存组的表观扩散系数(ADC)值在治疗第4周和第6周显著高于非生存组(均P<0.001)。曲线下面积分别为0.866和0.970,P值分别为0.001和<0.001,诊断准确率较好。Cox回归分析显示治疗第6周末的ADC是独立的危险因素。
    与食管造影和CT相比,DW-MRI在预测ESCC预后方面具有一定优势。
    UNASSIGNED: To identify the most sensitive imaging examination method to evaluate the prognosis of esophageal squamous cell carcinoma (ESCC).
    UNASSIGNED: Thirty patients with esophageal squamous cell carcinoma (ESCC) participated in the study and underwent chemoradiotherapy (CRT). They were divided into two groups based on their survival status: the survival group and non-survival group. The diagnostic tests were utilized to determine the most effective imaging examination method for assessing the prognosis.
    UNASSIGNED: 1. There were no significant differences in tumor length shown on esophagography or computed tomography (CT) or the maximal esophageal wall thickness shown on CT at the specified time points between the two groups. 2. The tumor length on diffusion-weighted imaging (DWI) in the survival group was significantly lower than in the non-survival group at the end of the sixth week of treatment (P=0.001). The area under the ROC curve was 0.840 (P=0.002), and the diagnostic efficiency was moderately accurate. 3. The apparent diffusion coefficient (ADC) values of the survival group were significantly higher than those in the non-survival group at the end of the fourth week and sixth week of treatment (both P<0.001). Areas under the curve were 0.866 and 0.970, with P values of 0.001 and <0.001 and good diagnostic accuracy. Cox regression analyses indicated the ADC at the end of the sixth week of treatment was an independent risk factor.
    UNASSIGNED: Compared with esophagography and CT, DW-MRI has certain advantages in predicting the prognosis of ESCC.
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  • 文章类型: Journal Article
    目的:该研究旨在展示“穿刺立方体”(PC)(医学模板,鸡蛋,瑞士)与CT引导穿刺的徒手法(FHM)进行比较。
    方法:PC是患者安装的可拆装立方体,由上下模板组成,每个模板都有多个孔,以预定义穿刺轨迹。总共80次穿刺(FHM平面内,FHM飞机下,PC在平面上,PC脱离平面)由4位放射科医师在氯丁橡胶覆盖的椭圆柱明胶体模表面以下9.1cm的目标上进行。PC从未被拆解。评估参数为手术时间,CT扫描次数,欧氏距离(ED)和正常距离(ND)。使用Wilcoxon符号秩检验和Levene检验比较FHM和PC的各自参数,显著性水平为5%。
    结果:PC在初次插入针后获得了较小的ED和ND值,而平面内和平面外穿刺均未校正(P>0.05)。对于FHM,初始ND的方差在平面外明显更大。对于平面内和平面外的FHM,针路校正后的最终ED较小(P<0.05)。FHM的最终平面外ND显着降低,最终平面内ND无显着差异。FHM的平面外穿刺明显更快。两种方法之间的CT扫描没有显着差异。
    结论:使用PC可以改善初始针头定位和安全性,尤其是离平面。然而,校正后更好的最终针定位与更大的运动自由度方法可能建议需要拆卸立方体。
    OBJECTIVE: The study aims to show how the \"Puncture Cube\" (PC) (Medical Templates, Egg, Switzerland) compares to the freehand method (FHM) for CT-guided punctures.
    METHODS: The PC is a patient-mounted disassemblable cube consisting of an upper and lower template with multiple holes each to predefine puncture trajectory. A total of 80 punctures (FHM in-plane, FHM off-plane, PC in-plane, PC off-plane) was performed by 4 radiologists on a target 9.1 cm below surface level of a neoprene covered elliptical cylinder gelatin phantom. The PC was never disassembled. Evaluated parameters were procedure time, number of CT-scans, euclidean distance (ED) and normal distance (ND). Respective parameters of FHM and PC were compared using the Wilcoxon signed-rank test and Levene test with significance levels of 5%.
    RESULTS: PC achieved smaller ED and ND values after initial needle insertion without corrections for both in-plane and off-plane punctures (P > 0.05). Variance of initial NDs was off-plane significantly larger for FHM. Final ED after needle path corrections was smaller for FHM both in- and off-plane (P < 0.05). Final off-plane ND was significantly lower for FHM with no significant difference in final in-plane ND. FHM off-plane punctures were significantly faster. There was no significant difference in CT-scans between both methods.
    CONCLUSIONS: Utilizing the PC may improve initial needle positioning and safety especially off-plane. However, better final needle positioning after correction with the greater freedom of movement method may suggest need for disassembly of the cube.
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  • 文章类型: Journal Article
    目的:本范围综述旨在评估当前人工智能(AI)的研究——通过CT扫描评价椎体骨小梁结构,增强机会性筛查方法对骨质疏松和骨质减少风险进行分层。
    方法:PubMed,Scopus,和WebofScience数据库被系统地搜索了2018年至2023年12月之间发表的研究。纳入标准包括专注于AI技术的文章,用于对骨质疏松症/骨质减少进行分类或使用椎体的CT扫描确定骨矿物质密度。数据提取包括研究特征,方法论,和关键发现。
    结果:14项研究符合纳入标准。确定了三种主要方法:全自动深度学习解决方案,将深度学习和传统机器学习相结合的混合方法,和非自动化解决方案,使用手动分割,然后进行AI分析。研究表明,在骨矿物质密度预测(86-96%)和正常与骨质疏松受试者的分类(AUC0.927-0.984)方面具有很高的准确性。然而,在方法论上观察到显著的异质性,工作流,和地面真相选择。
    结论:这篇综述强调了AI在使用CT扫描增强骨质疏松症机会性筛查方面的潜力。虽然该领域仍处于早期阶段,大多数解决方案都处于概念验证阶段,证据支持加大力度将人工智能纳入放射学工作流程.解决知识差距,例如标准化基准和增加外部验证,对于推进这些AI增强筛查方法的临床应用至关重要。这些技术的集成可以以较低的经济成本改善骨质疏松状况的早期检测。
    OBJECTIVE: This scoping review aimed to assess the current research on artificial intelligence (AI)--enhanced opportunistic screening approaches for stratifying osteoporosis and osteopenia risk by evaluating vertebral trabecular bone structure in CT scans.
    METHODS: PubMed, Scopus, and Web of Science databases were systematically searched for studies published between 2018 and December 2023. Inclusion criteria encompassed articles focusing on AI techniques for classifying osteoporosis/osteopenia or determining bone mineral density using CT scans of vertebral bodies. Data extraction included study characteristics, methodologies, and key findings.
    RESULTS: Fourteen studies met the inclusion criteria. Three main approaches were identified: fully automated deep learning solutions, hybrid approaches combining deep learning and conventional machine learning, and non-automated solutions using manual segmentation followed by AI analysis. Studies demonstrated high accuracy in bone mineral density prediction (86-96%) and classification of normal versus osteoporotic subjects (AUC 0.927-0.984). However, significant heterogeneity was observed in methodologies, workflows, and ground truth selection.
    CONCLUSIONS: The review highlights AI\'s promising potential in enhancing opportunistic screening for osteoporosis using CT scans. While the field is still in its early stages, with most solutions at the proof-of-concept phase, the evidence supports increased efforts to incorporate AI into radiologic workflows. Addressing knowledge gaps, such as standardizing benchmarks and increasing external validation, will be crucial for advancing the clinical application of these AI-enhanced screening methods. Integration of such technologies could lead to improved early detection of osteoporotic conditions at a low economic cost.
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  • 文章类型: Case Reports
    Omental梗塞是急性腹痛的罕见原因,通常是良性的和自我限制的。梗死的意义在于它可以模仿其他腹部病变,包括阑尾炎,胆囊炎,胰腺炎,或反流病。诊断性腹腔镜检查提供了大网膜梗塞的明确诊断,但它是侵入性的,由于资源有限。当需要非侵入性诊断方法时,腹部和骨盆的计算机断层扫描被认为是诊断网膜梗塞的金标准。此外,超声也可以用于儿童。目前,对影像学证实的网膜梗死患者的诊断和治疗尚无共识.外科医生和放射科医生必须将自发性梗塞网膜视为急性腹痛的罕见原因,因为患者可以通过保守或手术方法获得良好的结果。然而,只有在不可能有替代病理的稳定患者中,才应考虑保守治疗.
    Omental infarction is a rare cause of acute abdominal pain, often benign and self-limiting. The significance of infarction lies in the fact that it can mimic other abdominal pathologies including appendicitis, cholecystitis, pancreatitis, or reflux disease. Diagnostic laparoscopy provides the definitive diagnosis of omental infarction, but it is invasive and limited due to resources. Computed tomography of the abdomen and pelvis has been considered the gold standard to diagnosing omental infarction when a non-invasive diagnostic approach is required. Additionally, ultrasound can also be used alternatively for children. Currently, there is no consensus in the diagnosis and management of patients with imaging-proven omental infarction. Spontaneous infarcted omentum must be considered by surgeons and radiologists as a rare cause of acute abdominal pain as patients can experience good outcomes with either conservative or operative approach. However, conservative management must only be considered in stable patients where alternative pathology is unlikely.
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