PDF(Pubmed)
Abstract：
Brain abscesses in ruminants often arise from primary infection foci, leading to an unfavorable prognosis for affected animals. This highlights the need for comprehensive studies on brain abscesses across different ruminant species. We retrospectively investigated medical records of epidemiological, clinical, neuroimaging, anatomopathological, and bacteriological findings in six ruminants (three goats, two cows, and one sheep) diagnosed with brain abscesses. All animals studied were female. Apathy (50%), compulsive walking (33%), decreased facial sensitivity (33%), head pressing (33%), seizures (33%), semicomatous mental status (33%), strabismus (33%), unilateral blindness (33%), and circling (33%) represented the most common neurologic signs. Leukocytosis and neutrophilia were the main findings in the hematological evaluation. Cerebrospinal fluid (CSF) analysis revealed predominant hyperproteinorrachia and pleocytosis. In three cases, computed tomography or magnetic resonance imaging were used, enabling the identification of typical abscess lesions, which were subsequently confirmed during postmortem examination. Microbiological culture of the abscess samples and/or CSF revealed bacterial coinfections in most cases. Advanced imaging examinations, combined with CSF analysis, can aid in diagnosis, although confirmation typically relies on postmortem evaluation and isolation of the causative agent. This study contributes to clinicopathological aspects, neuroimages, and bacteriological diagnosis of brain abscesses in domestic ruminants.
摘要：
反刍动物的脑脓肿通常由原发感染灶引起，导致受影响动物的预后不良。这凸显了对不同反刍动物物种的脑脓肿进行全面研究的必要性。我们回顾性调查了流行病学的医疗记录，临床,神经影像学,解剖学病理学,和六只反刍动物的细菌学发现(三只山羊，两头母牛,和一只羊）被诊断患有脑脓肿。所有研究的动物都是雌性。冷漠（50%）强迫性行走（33%），面部敏感度下降（33%），压头（33%），缉获量(33%)，半乳质精神状态（33%），斜视（33%），单侧失明（33%），和盘旋（33％）是最常见的神经系统症状。白细胞增多和中性粒细胞增多是血液学评估的主要发现。脑脊液（CSF）分析显示主要是高蛋白质和细胞增多症。在三种情况下，使用计算机断层扫描或磁共振成像，能够识别典型的脓肿病变，随后在验尸中得到证实。在大多数情况下，脓肿样品和/或CSF的微生物培养物显示细菌共感染。先进的影像学检查，结合CSF分析，可以帮助诊断，尽管确认通常依赖于死后评估和病原体的隔离。这项研究有助于临床病理方面，神经影像，和家养反刍动物脑脓肿的细菌学诊断。
