磁性荧光复合纳米材料在生物成像领域具有广阔的应用前景,防伪鉴定,可疑物体跟踪,法医学中潜在指纹的鉴定。对于有效的标记物,一个清晰可见的识别标记是必要的,以使观察者能够快速准确地捕获标签信息,甚至从远处。磁性荧光复合材料的制备方法复杂,通常需要不同的表面改性和组装工艺。荧光材料有限的负载量也限制了复合材料的荧光性能,因此,很难产生明显的荧光作为标记物,以满足可见标记的要求。在这项研究中,通过使用金属-有机框架ZIF-8作为荧光材料的主体和包覆在Fe3O4纳米颗粒上的封装壳,制备了磁性荧光复合材料的核-壳结构。多孔ZIF-8有利于提高荧光材料的负载量,保证复合材料的荧光性能。复合材料表面的进一步改性防止了荧光材料从ZIF-8的孔中解吸,即使在多次洗涤循环后,样品也能保持良好的荧光性能。制备方法简单,快速,并且具有成本效益,制备的磁性荧光复合纳米材料具有较高的磁分离性能和荧光性能,使其成为有前途的鉴定材料,标记,跟踪。
Magnetic fluorescent composite nanomaterials have broad application prospects in the fields of biological imaging, anticounterfeiting identification, suspicious object tracking, and identification of latent fingerprints in forensic medicine. For an effective taggant, a clearly visible identifying mark is necessary to enable observers to capture labeling information quickly and accurately, even from a distance. The preparation method of magnetic fluorescent composite materials is complicated and usually needs different surface modification and assembly processes. The limited loading capacity of fluorescent materials also limits the fluorescence properties of the composite, so it is difficult to produce obvious fluorescence as a taggant to meet the requirements of visible labeling. In this study, a core-shell structure of a magnetic fluorescent composite was prepared by using the metal-organic framework ZIF-8 as the host of fluorescent materials and an encapsulation shell coated on the Fe3O4 nanoparticles. The porous ZIF-8 is beneficial for increasing the loading capacity of fluorescent materials to ensure the fluorescence performance of the composite materials. Further modification of the composite surface prevented the desorption of fluorescent materials from the pores of ZIF-8, enabling the samples to maintain good fluorescence properties even after multiple washing cycles. The preparation method is simple, rapid, and cost-effective, and the prepared magnetic fluorescent composite nanomaterial has high magnetic separation performance and fluorescence performance, making it a promising material for identification, marking, and tracking.