流感,COVID-19破伤风,百日咳和乙型肝炎对孕妇和婴儿的风险增加,可以通过孕产妇免疫来减轻。在印度,怀孕期间推荐使用破伤风白喉(Td)和COVID-19疫苗,而流感和破伤风-无细胞百日咳-白喉(Tdap)疫苗则没有。我们于2021年11月至2022年6月在西孟加拉邦三家公立医院的产前诊所就诊的孕妇(n=172)中进行了一项多中心研究。了解影响妇女决定在怀孕期间接种疫苗的因素。评估疫苗接种覆盖率的问题,知识,购买流感疫苗的意愿和意愿,以及影响获得Td决策的因素,流感,和COVID-19疫苗。152/172(88.4%)妇女接种了Td,159/172(93%)与COVID-19,1/172(0.6%)与流感,和Tdap没有。10/168(6%)已接受乙肝疫苗(HBV)。社区卫生工作者的建议对于Td的摄取至关重要,相信COVID-19疫苗可以预防COVID。大多数女性不知道Tdap(96%),流感(75%)和流感严重程度在怀孕和婴儿期(85%)。医疗保健提供者(HCP)没有建议接种流感疫苗,虽然,93%表示愿意服用,并为此支付100-300印度卢比(95%CI:≤100至300-500)[1.3-4.0美元(95%CI:≤1.3,4-6.7)]。在灵活的日期和时间接种疫苗,HCP的建议,靠近疫苗接种中心,和丈夫的支持对他们的疫苗接种决定是最重要的。妇女通常是疫苗的接受者,并且对普遍免疫计划(UIP)中包含的疫苗的摄取很高。包括流感,Tdap,HBV进入UIP可能会提高母体疫苗的摄取。
怀孕期间接种疫苗可保护母亲和婴儿免受破伤风的致命感染,流感,COVID-19,百日咳,在印度,所有孕妇都接种破伤风(Td)疫苗,在大流行期间,作为政府计划的一部分,孕妇接种了COVID-19疫苗。我们在西孟加拉邦三家公立医院就诊的孕妇中进行了一项研究,印度,在COVID-19大流行期间,了解影响妇女决定在怀孕期间接种疫苗的因素。我们发现大多数孕妇接种了Td(88.4%)和COVID-19(93%)疫苗;然而,流感的摄取量较低(0.6%),百日咳(0%),和乙肝疫苗(6%),这些疫苗在政府计划中都没有。尽管大多数女性(92%)没有听说过流感疫苗,一旦他们了解了他们,93%的人表示他们会接种疫苗,甚至为此付费。灵活的时间接种疫苗和医生的建议在他们决定接种疫苗时很重要。我们的研究建立了包括流感在内的案例,百日咳,和孕妇计划中的乙型肝炎疫苗。
Influenza, COVID-19, tetanus, pertussis and hepatitis B pose increased risk for pregnant women and infants and could be mitigated by maternal immunization. In India Tetanus-diphtheria (Td) and COVID-19 vaccines are recommended during pregnancy, while influenza and tetanus-acellular pertussis-diphtheria (Tdap) vaccines are not. We conducted a multicenter study from November 2021 to June 2022 among pregnant women (n = 172) attending antenatal clinics in three public hospitals in West Bengal, to understand the factors that influence women\'s decisions to get vaccinated during pregnancy. Questions assessed vaccination coverage, knowledge, intention and willingness to pay for influenza vaccine, and factors influencing decisions to get Td, influenza, and COVID-19 vaccines. 152/172 (88.4%) women were vaccinated with Td, 159/172 (93%) with COVID-19, 1/172 (0.6%) with influenza, and none with Tdap. 10/168 (6%) had received hepatitis B vaccine (HBV). Community health workers advice was crucial for Td uptake and, the belief of protection from COVID for COVID-19 vaccines. Most women were unaware about Tdap (96%), influenza (75%), and influenza severity during pregnancy and infancy (85%). None were advised for influenza vaccination by healthcare providers (HCP), albeit, 93% expressed willingness to take, and pay INR 100-300 (95% CI: ≤100 to 300-500) [$ 1.3-4.0 (95% CI: ≤1.3, 4-6.7)] for it. Vaccination on flexible dates and time, HCP\'s recommendation, proximity to vaccination center, and husband\'s support were most important for their vaccination decisions. Women were generally vaccine acceptors and had high uptake of vaccines included in the Universal Immunization Program (UIP). Inclusion of influenza, Tdap, and HBV into UIP may improve maternal vaccine uptake.
Vaccinations during pregnancy protect mothers and babies from lethal infections from tetanus, influenza, COVID-19, pertussis, and hepatitis B. In India all pregnant women get tetanus (Td) vaccines, and during the pandemic, pregnant women got COVID-19 vaccines as part of the government program. We conducted a study among pregnant women attending three public hospitals in West Bengal, India, during the COVID-19 pandemic to understand the factors that influence women’s decisions to get vaccinated during pregnancy. We found that most pregnant women had gotten Td (88.4%) and COVID-19 (93%) vaccines; however, the uptake was low for influenza (0.6%), pertussis (0%), and hepatitis B vaccines (6%) which are all not available in government programs. Though the majority (92%) of women had not heard about influenza vaccines, once they learnt about them, 93% said they would get vaccinated and even pay for it. Vaccination at flexible times and their doctor’s advice were important in their decisions to get vaccinated. Our research builds the case to include influenza, pertussis, and hepatitis B vaccines in programs for pregnant women.