关键词: COVID-19 pandemic United States misinformation mistrust vaccination vaccine acceptance vaccine hesitancy vaccine perceptions vaccine safety vaccine uptake

来  源:   DOI:10.3390/vaccines12070747   PDF(Pubmed)

Abstract:
The COVID-19 pandemic has presented the importance of vaccination as a pivotal strategy for controlling its spread. However, vaccine hesitancy poses a significant barrier to achieving widespread immunization in the United States. This systematic review utilizes the 5C model to examine the factors contributing to hesitancy, which include confidence in vaccines, complacency about disease risk, calculations of individual benefit, convenience of vaccination, and collective responsibility for the protection of others.
METHODS: We conducted a comprehensive search across several relevant databases and the gray literature, identifying 544 studies that used quantitative and qualitative methods to explore COVID-19 vaccine hesitancy in the general U.S.
METHODS:
RESULTS: This review identifies a complex interplay of factors affecting hesitancy, such as concerns over vaccine safety and efficacy, misinformation and conspiracy theories, demographic variables, and socioeconomic conditions. Key strategies for increasing vaccine uptake include transparent and effective communication along with proactive community engagement.
CONCLUSIONS: To effectively mitigate vaccine hesitancy, it is crucial to understand its multifaceted causes. Tailored interventions that consider socioeconomic and cultural contexts and prioritize clear communication, community involvement, and specific strategies to address unique concerns can enhance vaccine acceptance.
摘要:
COVID-19大流行表明了疫苗接种作为控制其传播的关键策略的重要性。然而,疫苗的犹豫是美国实现广泛免疫接种的重大障碍。本系统综述利用5C模型来检验导致犹豫的因素,其中包括对疫苗的信心,对疾病风险的自满,个人利益的计算,疫苗接种的便利性,以及保护他人的集体责任。
方法:我们对几个相关数据库和灰色文献进行了全面搜索,确定了544项研究,这些研究使用了定量和定性方法来探索美国一般情况下的COVID-19疫苗犹豫。
方法:
结果:本综述确定了影响犹豫的因素之间的复杂相互作用,例如对疫苗安全性和有效性的担忧,错误信息和阴谋论,人口统计学变量,和社会经济条件。提高疫苗使用率的关键策略包括透明和有效的沟通以及积极的社区参与。
结论:为了有效缓解疫苗犹豫,了解其多方面的原因至关重要。量身定制的干预措施,考虑社会经济和文化背景,并优先考虑明确的沟通,社区参与,和解决独特问题的具体策略可以提高疫苗的接受度。
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