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  • 文章类型: Journal Article
    在大数据时代,年轻患者可能会被基于人工智能的工具淹没,比如聊天机器人.五名临床专家被要求评估目前最常用的聊天机器人在提供影响年轻人的罕见癌症信息方面的性能。比如横纹肌肉瘤.一般来说,尽管他们在提供有关该疾病的一般信息方面表现出色,专家认为这些聊天机器人不足以提供有关癌症治疗和专业中心的建议,也缺乏“敏感性”。“儿科肿瘤社区计划努力提高用于训练这些工具的数据质量。
    In the era of big data, young patients may be overwhelmed by artificial intelligence-based tools, like chatbots. Five clinical experts were asked to evaluate the performance of the most currently used chatbots in providing information on a rare cancer affecting young people, like rhabdomyosarcoma. Generally speaking, despite their high performance in giving general information about the disease, these chatbots were considered by the experts to be inadequate in providing suggestions on cancer treatments and specialized centers, and also lacking in \"sensitivity.\" Efforts are planned by the pediatric oncology community to improve the quality of data used to train these tools.
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  • 文章类型: Journal Article
    泛心理主义和二元论的复兴是现代神经科学中正在进行的辩论。尽管形而上学上充满敌意,泛心理学和二元论都坚持在意识科学中,因为前者被提出作为将意识融入物理现实结构的问题的直接答案,而后者提出了一个简单的解决方案,通过赋予意识与因果权力作为道德责任的先决条件,自由意志的问题。我将综合信息理论(IIT)视为意识理论(ToC)的范例,该理论在统一的框架内致力于泛心理主义和二元论。这些特征不是,然而,独特的IIT。每当他们努力提出意识的普遍定义时,许多ToCs都隐含地倾向于某种程度的泛心理主义,与一种或另一种已知现象有关。然而,那些可以被定性为强烈涌现的拓扑结构有成为二元论的风险。在生命的进化理论中可以找到一种针对隐秘的二元论和不舒服的泛灵论推论的补救措施,这里称为“生物原心理学”,并在自体生成和自由能原理方面进行了概括。生物原心理学通过将弱紧急意识状态的流与大脑的大量信息(最佳猜测)相关联,为极简主义的意识方法提供了生物学启发的基础,从事无意识的预测处理。
    A resurgence of panpsychism and dualism is a matter of ongoing debate in modern neuroscience. Although metaphysically hostile, panpsychism and dualism both persist in the science of consciousness because the former is proposed as a straightforward answer to the problem of integrating consciousness into the fabric of physical reality, whereas the latter proposes a simple solution to the problem of free will by endowing consciousness with causal power as a prerequisite for moral responsibility. I take the Integrated Information Theory (IIT) as a paradigmatic exemplar of a theory of consciousness (ToC) that makes its commitments to panpsychism and dualism within a unified framework. These features are not, however, unique for IIT. Many ToCs are implicitly prone to some degree of panpsychism whenever they strive to propose a universal definition of consciousness, associated with one or another known phenomenon. Yet, those ToCs that can be characterized as strongly emergent are at risk of being dualist. A remedy against both covert dualism and uncomfortable corollaries of panpsychism can be found in the evolutionary theory of life, called here \"bioprotopsychism\" and generalized in terms of autopoiesis and the free energy principle. Bioprotopsychism provides a biologically inspired basis for a minimalist approach to consciousness via the triad \"chemotaxis-efference copy mechanism-counterfactual active inference\" by associating the stream of weakly emergent conscious states with an amount of information (best guesses) of the brain, engaged in unconscious predictive processing.
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  • 文章类型: Journal Article
    在多元化社会和健康危机期间提供健康信息时,护士能够适应移民的沟通是至关重要的,因为这可能会对他们的健康结果产生影响。这项研究旨在确定护士在COVID-19期间如何体验和评估他们与移民的沟通和信息工作,并讨论改进实践的措施。
    该研究具有解释性和探索性的定性设计,分析了对挪威市政卫生服务机构护士的10次半结构化访谈。
    创建了以下三个主题:多语言感染控制团队和与志愿者的合作,提供COVID-19信息时面临的挑战,以及护士在新的大流行或其他健康危机中的改进建议。
    护士的文化能力和他们对移民的知识健康素养可以帮助他们了解移民在患病期间的思维和行为。重要的是护士在健康危机期间使用谨慎。
    UNASSIGNED: When providing health information in a diverse society and during health crises, it is crucial that nurses can adapt their communication to immigrants, as this may have an impact on their health outcomes. This study seeks to identify how nurses experienced and assessed their communication and information work with immigrants during COVID-19 and to discuss measures to improve practice.
    UNASSIGNED: The study has an interpretive and explorative qualitative design, analyzing 10 semi-structured interviews with nurses from the municipal health service in Norway.
    UNASSIGNED: Three themes were created as follows: multilingual infection control teams and cooperation with volunteers, challenges when providing COVID-19 information, and the nurses\' suggestions for improvements in the event of a new pandemic or other health crisis.
    UNASSIGNED: Nurses\' cultural competence and their knowledge of immigrants\' health literacy can help them understand how immigrants think and behave during illness. It is important that nurses use discretion during health crises.
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  • 文章类型: Journal Article
    目的:本研究通过确定成功的新核心角色来探索卫生系统首席信息官(CIO)的不断发展的职位。
    方法:由行业高管和系统领导者组成的顾问委员会指导了这项研究。有目的的抽样用于邀请来自65个非营利性美国卫生系统的首席执行官和CIOs参加。采访了来自33个不同系统的51名高管,使用全面的面试主题指南。使用NVivo软件分析访谈记录,重点关注与卫生系统不断演变的作用有关的主题。
    结果:分析揭示了三个主要主题,将CIO作为(1)战略变革和转型的推动者,(2)技术和领导人才的战略开发人员,以及(3)组织文化的驱动力。
    结论:在更广泛的卫生系统背景下,CIO的角色经历了从技术和信息系统管理到战略领导的转变。它强调了全面的业务知识对于CIOs的重要性,以及其他高级管理人员对信息和技术有更深入了解的需求。
    结论:随着医疗保健的不断发展,CIO的作用有望进一步扩大,需要技术和战略业务技能的融合。这种演变为卫生系统提供了加强其领导力发展计划的机会,为当代卫生系统部门的复杂性做好准备。
    OBJECTIVE: This study explores the evolving position of the health system chief information officer (CIO) by identifying new core roles for success.
    METHODS: An advisory board of industry executives and system leaders guided the study. Purposeful sampling was used to invite chief executive officer and CIOs from 65 not-for-profit US health systems to participate. Interviews were conducted with 51 executives from 33 different systems, using a comprehensive interview topic guide. Interview transcripts were analysed using NVivo software, focusing on themes related to the evolving role of the health system CIO.
    RESULTS: Analyses revealed three main themes, with the CIO as (1) enabler of strategic change and transformation, (2) strategic developer of technology and leadership talent and (3) driver of organisational culture.
    CONCLUSIONS: The role of CIO has undergone transformation from technology and information system management to strategic leadership within the broader health system context. It highlights the importance of comprehensive business knowledge for CIOs and the need for other C-suite executives to have a deeper understanding of information and technology.
    CONCLUSIONS: As healthcare continues to evolve, the role of the CIO is expected to expand further, requiring a blend of technical and strategic business skills. This evolution presents opportunities for health systems to enhance their leadership development programmes, preparing leaders for the complexities of the contemporary health system sector.
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  • 文章类型: Journal Article
    在儿科肿瘤学中,出于许多原因,在整个护理途径中提出了遗传和基因组测试(例如,癌症表征,确定最合适的治疗方法,临床试验的患者选择,组织/器官捐献者的鉴定,或复发预测风险)。尽管有许多不同的方法(体细胞或种系测试,靶向基因或基因组测序),受牵连的个人面临着可能相交的情况,并且比较起来很有趣。没有研究确定和分析这些儿科肿瘤学新实践的可用工作。这篇叙述性文献综述的目的是描述癌症儿童的伦理和心理观点,父母,当基因或基因组检测被提议作为癌症管理的一部分时,医疗保健专业人员。18篇文章符合纳入标准,并使用MAXQDA进行了全面编码。他们的分析表明,关于遗传和基因组测试的主观含义,矛盾的领域(治疗的愿望,对知识的渴望,不确定性,患者及其父母报告的罪恶感)似乎反映了医疗保健专业人员的担忧。关于易感性测试的伦理和心理问题,在遗传性视网膜母细胞瘤和Li-Fraumeni综合征的背景下长期讨论,为更广泛地讨论儿科肿瘤学中的遗传和基因组检测途径提供了一个有用的起点.
    In pediatric oncology, genetic and genomic tests are proposed throughout the care pathway for many reasons (e.g., cancer characterization, identification of the most appropriate treatment, patient selection for clinical trials, identification of tissue/organ donors, or risk of relapse prediction). Despite the many different approaches (somatic or germline testing, targeted gene or genome sequencing), the implicated individuals are confronted with situations that may intersect and that are interesting to compare. No study has identified and analyzed the available works on these new practices in pediatric oncology. The aim of this narrative literature review was to describe the ethical and psychological perspectives of children with cancer, parents, and healthcare professionals when genetic or genomic testing is proposed as part of the cancer management. Eighteen articles met the inclusion criteria and were comprehensively coded using MAXQDA. Their analysis showed that concerning the subjective implications of genetic and genomic testing, the areas of ambivalence (desire of treatment, desire for knowledge, uncertainty, and guilt) reported by patients and their parents seem to mirror the healthcare professionals\' concerns. The ethical and psychological issues about predisposition testing, long discussed in the context of hereditary retinoblastoma and Li-Fraumeni syndrome, represent a useful starting point for a wider discussion of a genetic and genomic testing pathway in pediatric oncology more broadly.
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  • 文章类型: Journal Article
    许多人怀疑生物学,包括人类,将从人工智能(AI)等信息的新发展中受益或受到伤害。这里,建议生物和非生物信息可能是统一过程的组成部分,\'Panevolution\'或\'Pan-Evo\',基于四个基本操作-创新,传输,适应,和运动。Pan-Evo包含许多类型的可变对象,从分子到生态系统。生物创新包括突变和行为变化;非生物创新包括自然发生的物理创新和软件创新。复制在生物学内外都很普遍,包括自动催化化学品和自主软件复制。适应包括生物选择,自动催化化学品,和“进化编程”,这是在AI中使用的。生物物种形成对非生物信息的扩展产生了一个称为“全物种形成”的概念。泛进化可能对生物学有益或有害,但如果人工智能和人类的行为智能,危害可能是最小的,因为人类和人工智能所在的机器可能会分裂成适合他们的截然不同的环境。这是一个可能的例子,也是数千年来第一个涉及人类的物种形成事件。如果人类学会评估信息并更好地合作,以最大程度地减少人类的愚蠢和人工模拟的愚蠢(ASS-AI的失败),那么这一事件将不会对人类特别不利。
    Many people wonder whether biology, including humans, will benefit or experience harm from new developments in information such as artificial intelligence (AI). Here, it is proposed that biological and non-biological information might be components of a unified process, \'Panevolution\' or \'Pan-Evo\', based on four basic operations-innovation, transmission, adaptation, and movement. Pan-Evo contains many types of variable objects, from molecules to ecosystems. Biological innovation includes mutations and behavioural changes; non-biological innovation includes naturally occurring physical innovations and innovation in software. Replication is commonplace in and outside biology, including autocatalytic chemicals and autonomous software replication. Adaptation includes biological selection, autocatalytic chemicals, and \'evolutionary programming\', which is used in AI. The extension of biological speciation to non-biological information creates a concept called \'Panspeciation\'. Panevolution might benefit or harm biology, but the harm might be minimal if AI and humans behave intelligently because humans and the machines in which an AI resides might split into vastly different environments that suit them. That is a possible example of Panspeciation and would be the first speciation event involving humans for thousands of years. This event will not be particularly hostile to humans if humans learn to evaluate information and cooperate better to minimise both human stupidity and artificial simulated stupidity (ASS-a failure of AI).
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  • 文章类型: Journal Article
    越来越多的患者提前出院,越来越多的患者有复杂的医疗保健需求,并在初级医疗保健部门接受护理。为了确保护理的有效协调和连续性,获取相关信息至关重要。我们从两个挪威城市报告说,在一个创新项目中,将他们的信息系统从纸质系统转移到数字协调系统。举办了讲习班和访谈,以解决这些考虑因素,创新过程中参与者的反思和困境。分析提供了三个主要主题,分别是:1)从纸质到数字概述的过渡;2)从单个患者信息过渡到患者群体的数字概述;3)从使用电话过渡到信息的数字交换。演员们必须克服几个挑战。然而,结果是,他们获得了符合情境的信息,从而提高了协调工作的效率和患者安全.
    More patients are being discharged early from hospital and increasing numbers of patients have complex health care needs and receive care in the primary health care sector. To ensure efficient coordination and continuity of care, access to relevant information is crucial. We report from two Norwegian municipalities that, during an innovation project, transferred their information system from a paper-based to a digital coordination system. Workshops and interviews were conducted to address the considerations, reflections and dilemmas of the actors involved during the innovation process. The analysis provided three main themes which were: 1) transition from paper-based to digital overviews; 2) transition from individual patient information to a digital overview of groups of patients; and 3) transition from use of telephone to digital exchange of information. The actors had to overcome several challenges. Nevertheless, the outcome was that they were provided with contextualised information enabling efficiency and patient safety in their coordination work.
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  • 文章类型: Journal Article
    人力资源管理(HRM)中的正确性和真实验证数据对组织很重要,因为数据在招聘中起着重要作用,发展,并保留熟练的劳动力。一方面,组织中经过验证的数据有助于招聘合法的熟练员工;另一方面,保护员工的数据安全和维护隐私法律,如遵守一般数据保护条例(GDPR)也是组织的责任。此外,在人力资源管理操作的透明度是至关重要的,因为它促进了信任和公平的组织。当前的人力资源管理系统本质上是集中的,其可验证的凭证系统无效;这导致了内部数据破坏或内部威胁的意图。此外,组织的偏见也变得更加突出。在本文中,我们通过HRM的区块链框架来解决上述问题,以通过隐私信息检索(PIR)过程来利用数据访问的隐私。具体而言,我们提出的框架称为Resources的BlockchainedPiR作为humaN(BRON),是第一个显示有效机制的区块链框架,可以在不妨碍隐私的情况下访问全球组织的数据。BRON使用通用的用户注册过程来使用数据访问和后台服务,它使用零知识证明(ZKP)进行全局验证,使用PIR进行基于隐私的数据检索。更具体地说,凭证验证和基于ZKP的PIR是我们提出的BRON的亮点。BRON的另一个有趣的方面是使用授权证明(PoA)来验证任何HR操作的匿名性和不可链接性。最后,BRON还提供了一份智能合约来激励员工。BRON是非常通用的,很容易根据HR要求进行定制。我们在BRON上进行了一系列实验,并观察到它在提供隐私保证的数据访问和分散的人力资源数据管理方面是成功的。总的来说,与现有的区块链解决方案相比,BRON在人力资源管理方面提供了30%的延迟减少和35%的吞吐量。
    The correctness and the true validated data in Human Resource Management (HRM) are important for organizations as the data plays an impactful role in recruiting, developing, and retaining a skilled workforce. On one hand, the validated data in an organization helps in recruiting legitimate skillful employees; on the other hand, keeping the employee\'s data safe and maintaining privacy laws such as compliance with the General Data Protection Regulation (GDPR) is also an organization\'s responsibility. Besides, transparency in human resource management operations is crucial because it promotes trust and fairness within an organization. The present HRM systems are centralized in nature and their verifiable credential system is ineffective; this leads to the intentions of internal data sabotage or internal threats. Besides, the organizations\' biases also become more prominent. In this paper, we address the above-mentioned problems with a blockchain framework for HRM to utilize the privacy of data access through a Privacy Information Retrieval (PIR) process. To be specific, our proposed framework called Blockchained piR of resOurces as humaN (BRON), is the first blockchain framework to show an effective mechanism to access data from organizations globally without hampering privacy. BRON uses a generalized user registration process to use the services of data access and in the background, it uses Zero-Knowledge Proofs (ZKPs) for global verification and PIR for privacy-based data retrieval. More specifically, credential verification and ZKP-based PIR are the highlights of our proposed BRON. Another interesting aspect of BRON is the use of Proof-of-Authority (PoA) to validate the anonymity and unlinkability of any HR operation. Finally, BRON has also contributed with a smart contract to incentivize the employees. BRON is very generic and easily be customizable as per the HR requirements. We run a set of experiments on BRON and observe that it is successful in providing privacy-assured data access and decentralized human resource data management. Overall, BRON provides 30% reduced latency and 35% better throughput as compared to the existing blockchain solutions in the direction of HRM.
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  • 文章类型: Journal Article
    Care,管理,和法规,每个都要求在英国的精神病环境中进行限制报告。本期刊中的PROD-ALERT(“PA1”)与约束的对数发生率相关,日志机构规模,记录拘留。期间为2020年9月至2021年8月。这在记者中显示出明显的趋势。限制与机构规模和合法拘留的使用有关。尽管有这种趋势,一些大型拘留提供者仍报告每月没有限制。从规模上的推断表明,不完整的记者每月限制1,774人。这篇论文“PA2”开发了2021年9月至2022年8月重复它的分析。PA2显示如何计算L信息,即,可疑信息,由空报告添加,通过对数据集应用L检验。PA2使用有关人类身高的说明性插图来根据英语约束报告中的L信息得分。在PA2中,报告的克制再次与PA1中的规模和拘留有关。PA2显示了不断发展的数据。供应商仍然遵循规模和拘留限制的趋势。新报告克制的供应商正在趋势。推论表明,不完整的记者每月限制1,305人(536-3233),95%CI,自PA1以来数量较大但减少。英语约束数据的L测试L信息分数为信息增加了L=145。这与声称平均1.72米的英国男子身高2.64米一样令人惊讶。每月被限制的人数是一项强有力的措施,继续与规模和法律强制相关。报告无效限制的一定规模的提供商可能有一些。在英格兰,克制仍然被低估。对不完整的记者的填补显示,大量患者被不完整的记者拘留。了解这一点可以促进报告。改进报告,以及它所要求的基础设施和完整性,可以帮助提供者衡量和减少约束。PA1仍未反驳。L检验可以以直观表示的方式测量L信息。零位对可靠数据集的信息影响类似于声称平均身高男性与临床巨人症患者一样高的说法。
    Care, management, and statute each mandate restraint-reporting in psychiatric settings in England. PROD-ALERT in this journal (\"PA1\") correlated log incidence of restraint, log institutional size, and log detention. The period was September 2020 to August 2021. It showed a clear trend among reporters. Restraint correlated with institutional size and use of legal detention. Some large detaining providers reported no restraints per month despite that trend. Inference from size suggested that non-complete reporters restrained 1,774 people per month. This paper \"PA2\" develops analysis repeating it for September 2021 to August 2022. PA2 shows how to count L-information, i.e., questionable information, added by null reports, by applying an L-test to data sets. PA2 uses illustrative vignettes about human height to ground L-information scores from English restraint reporting. In PA2, reported restraint again correlates with size and detention as in PA1. PA2 shows evolving data. Providers still follow a trend in restraint by size and detention. Providers which newly report restraint are on trend. Inference suggests that non-complete reporters restrained 1,305 people per month (536-3233), 95% CI, a large but reduced number since PA1. English restraint data have an L-test L-information score of increase in information by a factor of L = 145. This is as surprising as claiming that an average English man of 1.72 m is 2.64 m tall. Persons restrained per month is a robust measure continuing to log-correlate with size and legal compulsion. Providers over a certain size who report null restraint probably have some. Restraint remains underreported in England. Imputation of incomplete reporters shows a large shrinking cohort of patients detained by incomplete reporters. Knowledge of this may promote reporting. Improved reporting, and the infrastructure and integrity it demands, may help providers measure and reduce restraint. PA1 remains unrefuted. L-test can measure L-information in intuitively representable ways. The informational effect of nulls on the reliable data set is similar to a claim that an average-heighted man is as tall as people with clinical gigantism.
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  • 文章类型: Journal Article
    目的:癌症与迫切需要可理解和可靠的信息有关,这通常不能被网上提供的信息所满足。因此,作为PIKKO项目的一部分,引入了基于网络的知识数据库(WDB),为癌症患者提供质量保证,基于证据的信息。本文旨在提供有关WDB的用法(谁?如何?什么?)和对健康素养的影响的见解。
    方法:评估患者调查和自动生成的日志文件数据。两个用户组,患者和患者导航员(PNs),进行了比较。
    结果:在整个项目期间,13个PN占所有访问的1/3。413名患者平均使用WDB两次,平均每次在线花费12分钟(PN:每次9分钟,更频繁地)。最感兴趣的三个主题是“治疗”,患者的“营养”和“致癌作用”,和“治疗”,PNs的“自然疗法”和“法律法规/支持”。在接受调查的病人中,69%的人表示WDB有助于做出明智的决定,76%的人找到了他们想要的信息,90%的人认为WDB是提供信息的合适方式。
    结论:我们的WDB以数字方式提供了有关癌症及其治疗的重要信息,患者和PNs。在常规癌症护理中,WDB可以提高健康素养和明智的决策。
    背景:该研究在DRKS00016703(2019年2月21日,回顾性注册)的德国临床试验注册中进行了回顾性注册。https://www.drks.de/drks_web/navigate。做什么?navigationId=审判。HTML&TRIAL_ID=DRKS00016703。
    OBJECTIVE: Cancer is associated with an urgent need for understandable and reliable information, which is often not satisfied by information available online. Therefore, as part of the PIKKO project, a web-based knowledge database (WDB) was introduced to provide cancer patients with quality-assured, evidence-based information. This paper aims to provide insights into the usage (Who? How? What?) and the effects regarding health literacy of the WDB.
    METHODS: A patient survey and automatically generated logfile data were evaluated. Two user groups, patients and patient navigators (PNs), were compared.
    RESULTS: The 13 PNs were responsible for 1/3 of all accesses over the entire duration of the project. The 413 patients used WDB twice on average and spent an average of 12 min per session online (PNs: 9 min per session, more frequently). The top 3 topics of interest were \'therapy\', \'nutrition\' and \'carcinogenesis\' for the patients, and \'therapy\', \'naturopathy\' and \'legal regulations/support\' for the PNs. Of the patients surveyed, 69% said that WDB was helpful in making informed decisions, 76% found the information they wanted and 90% thought WDB was an appropriate way to provide information.
    CONCLUSIONS: Our WDB provided important information about cancer and its treatment on a digital way both, to patients and PNs. In routine cancer care, the WDB can improve health literacy and informed decision-making.
    BACKGROUND: This study was retrospectively registered in the German Clinical Trial Register under DRKS00016703 (21 Feb 2019, retrospectively registered). https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00016703.
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