宫颈癌仍然是全球健康挑战,每年夺去数百万人的生命,并对海湾合作委员会(GCC)国家产生重大影响。人乳头瘤病毒(HPV),主要病原体,起着核心作用,1从HPV感染到肿瘤性变化的过程需要5-25年才能发生,因此,知道它在我们社区的流行是至关重要的2。
■搜索PubMed和SCOPUS以确定与卡塔尔的宫颈和生殖器HPV患病率和基因型有关的文章,科威特,巴林,阿曼,阿拉伯联合酋长国(UAE),和沙特阿拉伯王国(KSA)在2017年至2024年之间发布。
■本综述共包括19篇文章。八项研究来自KSA,四人来自科威特,三个来自阿联酋,一个来自卡塔尔,阿曼,巴林,一个人提供了来自KSA的数据,阿联酋,卡塔尔,和巴林。在KSA的研究中,HPV的患病率在4.7%到77%之间。在科威特的研究中,15%到54.3%之间,在阿联酋的研究中,14.7%到88%之间,在卡塔尔的两项研究中,分别为8.1%和31.3%,在阿曼和巴林的研究中,分别为17.8%和20%,分别。HPV16是在KSA中进行的研究中发现的最普遍的高危基因型,阿联酋,科威特,卡塔尔。在阿曼,HPV82占优势。在巴林,大多数患者有其他非HPV16/18/45基因型.在阿联酋和科威特,HPV11是主要的低危型,其次是HPV6。在卡塔尔,HPV81是最常见的低危型。其次是HPV11。在阿曼,HPV54是最常见的低危型。其次是HPV42。
■在海湾合作委员会国家,没有关于接种HPV疫苗的女性HPV流行率和基因型数据的研究。
UNASSIGNED: Cervical cancer remains a global health challenge, claiming the lives of millions annually and having a significant impact on Gulf Cooperation Council (GCC) countries. Human papillomavirus (HPV), the primary causative agent, plays a central role, with regional variations in prevalence.1 The process from HPV infection to neoplastic changes takes 5-25 years to occur, hence, knowing its prevalence in our community is vital.2.
UNASSIGNED: PubMed and SCOPUS were searched to identify articles related to cervical and anogenital HPV prevalence and genotypes in Qatar, Kuwait, Bahrain, Oman, the United Arab Emirates (UAE), and the Kingdom of Saudi Arabia (KSA) published between 2017 and 2024.
UNASSIGNED: A total of 19 articles were included in this review. Eight studies were from KSA, four were from Kuwait, three were from the UAE, one was from Qatar, Oman, and Bahrain, and one presented data collectively from the KSA, UAE, Qatar, and Bahrain. The prevalence of HPV ranged between 4.7% and 77% in studies from the KSA, between 15% and 54.3% in studies from Kuwait, between 14.7% and 88% in studies from the UAE, was 8.1% and 31.3% in the two studies from Qatar, and was 17.8% and 20% in the studies from Oman and Bahrain, respectively. HPV 16 was the most prevalent high-risk genotype found in studies conducted in the KSA, UAE, Kuwait, and Qatar. In Oman, HPV 82 predominated. In Bahrain, the majority had other non-HPV 16/18/45 genotypes. In the UAE and Kuwait, HPV 11 was the predominant low-risk type, followed by HPV 6. In Qatar, HPV 81 was the most common low-risk type, followed by HPV 11. In Oman, HPV 54 was the most common low-risk type, followed by HPV 42.
UNASSIGNED: There are no studies with data on HPV prevalence and genotypes among women who have been vaccinated against HPV in GCC countries.