UNASSIGNED:研究发现,由于多种原因,亚洲地区的男男性行为者(MSM)感染艾滋病毒和性传播感染(STIs)的风险非常高。尽管亚洲普通人群中艾滋病毒的流行率被认为很低,该地区MSM中艾滋病毒和梅毒的患病率很高,通常,它被忽视了。这项研究旨在检查艾滋病毒的流行和趋势,梅毒,以及它们在亚洲MSM中的共同感染。
UNASSIGNED:2021年1月5日在PubMed进行了系统搜索,WebofScience,和谷歌学者数据库。为了评估异质性,Q-tests,我2被使用。为了探索出版偏见,使用Eggers\'测试和漏斗图。由于存在显著的异质性,进行了随机效应模型和亚组分析。
未经批准:共确定了2872篇文章,66篇文章被纳入最终分析。考虑到66项研究的69项估计值,估计了MSM中HIV和梅毒的总体患病率,而在17项研究中发现了19项共感染的估计值。合并的HIV患病率为8.48%(CI:7.01-9.95),合并的梅毒患病率为9.86%(CI:8.30-11.41),具有显着的异质性和发表偏倚。HIV和梅毒合并感染的合并患病率为2.99%(CI:1.70-4.27),具有显着的异质性,没有发表偏倚。艾滋病毒,梅毒,在2002-2017年期间,HIV-梅毒合并感染率估计值呈上升趋势.
未经批准:艾滋病毒,梅毒,它们的共同感染在亚太地区的MSM中相当普遍。综合和强化干预战略,艾滋病毒检测,需要改善获得抗逆转录病毒治疗的机会,并提高人们的认识,以减少艾滋病毒,梅毒,以及他们在讨论的弱势群体中的共同感染。
UNASSIGNED: Studies found that the group of men who have sex with men (MSM) is at a very high level of risk of HIV and sexually transmitted infections (STIs) in Asian regions due to multiple reasons. Although the prevalence of HIV among general people in Asia is considered low, the prevalence of HIV and Syphilis among MSM in this region was found very high and usually, it goes unnoticed. This study aimed to inspect the prevalence of and trends in HIV, Syphilis, and their co-infection among MSM in Asia.
UNASSIGNED: A systematic search was performed on January 5, 2021, in PubMed, Web of Science, and Google Scholar databases. To evaluate the heterogeneity, Q-tests, and I 2 were used. To explore the publication bias, Eggers\' test and funnel plot were used. The random-effect model and subgroup analysis were performed due to the significant heterogeneity.
UNASSIGNED: A total of 2872 articles were identified, and 66 articles were included in the final analysis. The overall prevalence of HIV and Syphilis among MSM was estimated considering 69 estimates from 66 studies whereas 19 estimates of co-infection were found in 17 studies. The pooled HIV prevalence was 8.48% (CI: 7.01-9.95) and the pooled Syphilis prevalence was 9.86% (CI: 8.30-11.41) with significant heterogeneity and publication bias. The pooled prevalence of HIV and Syphilis co-infection was 2.99% (CI: 1.70-4.27) with significant heterogeneity and no publication bias. The HIV, Syphilis, and HIV-Syphilis co-infection prevalence estimates exhibited an upward trend during 2002-2017.
UNASSIGNED: HIV, Syphilis, and their co-infection are quite prevalent among MSM in the Asia-Pacific region. Integrated and intensified intervention strategies, HIV testing, and improved access to antiretroviral treatment as well as increased awareness are needed to reduce HIV, Syphilis, and their co-infection among the discussed vulnerable group.