PDF(Pubmed)
Abstract：
UNASSIGNED: In 2019, there were over 1.1 million people living with human immunodeficiency virus (HIV) and 2.4 million people living with hepatitis C virus (HCV) in the United States. One in seven (14%) are unaware of their HIV infection and almost half of all HCV infections are undiagnosed. People with unstable housing are disproportionately affected by HIV and HCV. The present study will evaluate interventions by community pharmacists that may reduce HIV and HCV transmission and promote linkage to care.
UNASSIGNED: This study was conducted in an independent community pharmacy in Spokane, Washington. Eligible study participants were walk-in patients of the pharmacy, over the age of 18, and experiencing homelessness. Pharmacy patients were excluded if they had a history of HIV or HCV diagnosis, received a screening for HIV or HCV in the last six months or were unable to give informed consent. The intervention included administration of HIV and HCV point-of-care testing (POCT) using a blood sample, risk determination interview, comprehensive HIV and HCV education, and personalized post-test and risk mitigation counseling followed by referral to partnering health clinics.
UNASSIGNED: Fifty participants were included in the final data analysis. Twenty-two participants (44%) had a reactive HCV POCT, and one participant had a reactive HIV POCT. Of the 94% of participants who reported illicit drug use, 74% reported injection drug use. Seventy-six percent (n = 38) qualified for PrEP. Pharmacist referrals were made for 28 participants and 71% were confirmed to have established care.
UNASSIGNED: Individuals experiencing homelessness are at an increased risk for acquiring HIV and HCV due to risky sexual behaviors and substance misuse. PrEP is underutilized in the U.S. and pharmacist involvement in the HIV and HCV care continuum may have a significant impact in improving linkage and retention in care of difficult to treat populations.
UNASSIGNED: This study was conducted in an independent community pharmacy in Spokane, Washington. Eligible study participants were walk-in patients of the pharmacy, over the age of 18, and experiencing homelessness. Pharmacy patients were excluded if they had a history of HIV or HCV diagnosis, received a screening for HIV or HCV in the last six months or were unable to give informed consent. The intervention included administration of HIV and HCV point-of-care testing (POCT) using a blood sample, risk determination interview, comprehensive HIV and HCV education, and personalized post-test and risk mitigation counseling followed by referral to partnering health clinics.
UNASSIGNED: Fifty participants were included in the final data analysis. Twenty-two participants (44%) had a reactive HCV POCT, and one participant had a reactive HIV POCT. Of the 94% of participants who reported illicit drug use, 74% reported injection drug use. Seventy-six percent (n = 38) qualified for PrEP. Pharmacist referrals were made for 28 participants and 71% were confirmed to have established care.
UNASSIGNED: Individuals experiencing homelessness are at an increased risk for acquiring HIV and HCV due to risky sexual behaviors and substance misuse. PrEP is underutilized in the U.S. and pharmacist involvement in the HIV and HCV care continuum may have a significant impact in improving linkage and retention in care of difficult to treat populations.
摘要：
UNASSIGNED：在2019年，美国有超过110万人患有人类免疫缺陷病毒（HIV），240万人患有丙型肝炎病毒（HCV）。七分之一（14％）不知道他们的HIV感染，几乎一半的HCV感染未被诊断。住房不稳定的人不成比例地受到艾滋病毒和HCV的影响。本研究将评估社区药剂师的干预措施，这些干预措施可能会减少HIV和HCV的传播并促进与护理的联系。
UNASSIGNED：这项研究是在斯波坎的一家独立社区药房进行的，华盛顿。符合条件的研究参与者是药房的步入式患者，18岁以上，经历无家可归。如果药房患者有HIV或HCV诊断史，则将其排除在外。在过去6个月内接受了HIV或HCV筛查,或无法给予知情同意.干预措施包括使用血液样本进行HIV和HCV即时检测（POCT），风险确定面试，全面的HIV和HCV教育，以及个性化的测试后和风险缓解咨询，然后转诊到合作的健康诊所。
UNASSIGNED：最终数据分析包括50名参与者。22名参与者（44％）有反应性HCVPOCT，和一个参与者有一个反应性HIVPOCT。在94%报告使用非法药物的参与者中，74%的人报告使用注射药物。百分之七十六（n=38）符合PrEP。对28名参与者进行了药剂师转诊，其中71％被确认为已建立的护理。
未经评估：由于危险的性行为和物质滥用，无家可归的人感染艾滋病毒和HCV的风险增加。PrEP在美国未得到充分利用，药剂师参与HIV和HCV连续护理可能对改善联系和保留难以治疗人群的护理产生重大影响。
UNASSIGNED：这项研究是在斯波坎的一家独立社区药房进行的，华盛顿。符合条件的研究参与者是药房的步入式患者，18岁以上，经历无家可归。如果药房患者有HIV或HCV诊断史，则将其排除在外。在过去6个月内接受了HIV或HCV筛查,或无法给予知情同意.干预措施包括使用血液样本进行HIV和HCV即时检测（POCT），风险确定面试，全面的HIV和HCV教育，以及个性化的测试后和风险缓解咨询，然后转诊到合作的健康诊所。
UNASSIGNED：最终数据分析包括50名参与者。22名参与者（44％）有反应性HCVPOCT，和一个参与者有一个反应性HIVPOCT。在94%报告使用非法药物的参与者中，74%的人报告使用注射药物。百分之七十六（n=38）符合PrEP。对28名参与者进行了药剂师转诊，其中71％被确认为已建立的护理。
未经评估：由于危险的性行为和物质滥用，无家可归的人感染艾滋病毒和HCV的风险增加。PrEP在美国未得到充分利用，药剂师参与HIV和HCV连续护理可能对改善联系和保留难以治疗人群的护理产生重大影响。
