Craniocerebral Trauma

颅脑外伤
  • 文章类型: Journal Article
    婴儿期死亡和残疾的主要原因是虐待性头部创伤(AHT),并且有共同的临床体征有助于建立这种诊断。诊断为AHT的儿童可以有许多眼科检查结果,包括视网膜出血,视网膜分裂,结膜下出血,角膜损伤,和地球破裂。如果怀疑有这样的伤害,眼科咨询,间接检眼镜,应该完成。除了完整的体检,彻底的历史成像,和实验室工作,应获得以调查眼科病理的病因,包括意外和全身原因。总的来说,研究表明,视网膜出血是多层的,数不胜数,从后极到锯齿的位置高度怀疑虐待性头部创伤。
    A leading cause of death and disability in infancy is abusive head trauma (AHT) and there are common clinical signs that help to establish this diagnosis. Children diagnosed with AHT can have many ophthalmologic findings, including retinal hemorrhages, retinoschisis, subconjunctival hemorrhages, corneal injury, and globe rupture. If any such injuries are suspected, an ophthalmologic consultation, with indirect ophthalmoscopy, should be completed. In addition to a complete physical exam, a thorough history imaging, and lab work, should be obtained to investigate the etiology of ophthalmic pathology including accidental and systemic causes. In general, studies show that retinal hemorrhages that are multilayered, too numerous to count, and located from the posterior pole to the ora serrata are highly suspicious for abusive head trauma.
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  • 文章类型: Journal Article
    这篇关于虐待性头部创伤的重点综述描述了头部的伤害,婴儿或幼儿遭受创伤的大脑和/或脊柱及其神经影像学相关性。准确识别和诊断虐待性头部创伤对于防止反复受伤至关重要,及时治疗,并确保已考虑到意外或潜在的医疗原因。在这篇文章中,我们的目的是讨论与AHT相关的神经影像学的各种发现,与那些与意外伤害或潜在医疗原因更一致的人相比,这些原因也可能存在差异。
    This focused review on abusive head trauma describes the injuries to the head, brain and/or spine of an infant or young child from inflicted trauma and their neuroimaging correlates. Accurate recognition and diagnosis of abusive head trauma is paramount to prevent repeated injury, provide timely treatment, and ensure that accidental or underlying medical contributors have been considered. In this article, we aim to discuss the various findings on neuroimaging that have been associated with AHT, compared to those that are more consistent with accidental injuries or with underlying medical causes that may also be on the differential.
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  • 文章类型: Journal Article
    与意外头部损伤相比,虐待性头部损伤(AHT)与高死亡率和较差的预后有关。AHT的短期和长期发育结果尚未得到很好的确定。结果测量的变异性,小样本量,难以测量特定领域的发展技能,共存的合并症,遗传和环境因素以及高流失率都给在这一领域提供数据带来了挑战。本文的目的是回顾有关AHT发展结果的科学文献,突出影响结果的因素,可用的评估工具,以及短期和长期的发展成果,建议跟进,社会成本,和未来的研究机会。作者在OVIDMedline和PubMed搜索了2013年至2023年之间发表的文章,使用术语“滥用”,“颅脑外伤”和“发展”。本次审查包括55条记录。数据显示,AHT造成的伤害会导致从正常发育到死亡的一系列结果。有100多种结果评估工具限制了比较研究的能力。超过一半的患者在出院后留下残疾。粗大运动和认知/学术是研究的两个最常见的领域。外科和神经重症监护管理的进步影响了AHT的结果。建议长期密切随访,以最大限度地提高每个孩子的发展潜力,无论出院时是否有残疾。我们建议未来的研究应侧重于采用一致的诊断和评估方法,并探索可能影响恢复的社会环境因素。
    Abusive head trauma (AHT) is associated with high mortality and poorer outcomes compared to accidental head injuries. The short and long-term developmental outcomes for AHT are not well identified. Variability in outcome measures, small sample sizes, difficulty in measuring domain-specific developmental skills, co-existence of comorbidities, genetic and environmental factors and high attrition rates all contribute to the challenges on providing data in this area. The objective of this article is to review the scientific literature on the developmental outcomes of AHT, highlighting factors that affect outcomes, the available assessment tools, and short and long-term developmental outcomes, recommended follow up, societal costs, and future opportunities for research. Authors searched OVID Medline and PubMed for articles published between 2013 and 2023 using the terms \"abuse\", \"craniocerebral trauma\" and \"development\". Fifty-five records were included for this review. The data shows that injuries sustained from AHT result in a spectrum of outcomes ranging from normal development to death. There are more than 100 outcome assessment tools limiting the ability to compare studies. More than half of patients are left with disabilities post discharge. Gross motor and cognition/academics are the 2 most common domains studied. Advancement in surgical and neurocritical care management has influenced AHT outcomes. Close long-term follow up is recommended to maximize each child\'s developmental potential, irrespective of the presence of disability at discharge. We suggest that future research should focus on adopting a consistent diagnostic and assessment approach and explore the social environmental factors that can affect recovery.
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  • 文章类型: Journal Article
    虐待儿童是美国发病率和死亡率的主要原因。与儿童身体虐待相关的死亡的主要原因是虐待性头部创伤,以前被称为动摇婴儿综合症,对这些儿童的快速识别和评估至关重要。虐待性头部创伤病例的临床表现包括神经系统疾病,比如癫痫发作,模糊或微妙的症状,比如呕吐。这导致经常漏诊虐待性头部创伤。虐待性头部创伤的鉴定依赖于彻底的病史和体格检查,其次是实验室评估和成像。评估的目的是发现进一步的损伤并确定患者症状的潜在非创伤性病因。在本文中,我们提出了一个评估虐待性头部创伤的框架,并提供了有关常见表现和伤害的信息,以及鉴别诊断。对虐待性头部创伤的强大基础知识将为这种不幸诊断的受害者带来更大的认可和改进的安全计划。
    Child abuse is a major cause of morbidity and mortality in the United States. The leading cause of child physical abuse related deaths is abusive head trauma, formerly known as shaken baby syndrome, making the rapid identification and assessment of these children critical. The clinical presentation of cases of abusive head trauma ranges from neurological complaints, such as seizures, to vague or subtle symptoms, such as vomiting. This results in frequent missed diagnoses of abusive head trauma. The identification of abusive head trauma relies on a thorough medical history and physical examination, followed by lab evaluation and imaging. The goal of the evaluation is to discover further injury and identify possible underlying non-traumatic etiologies of the patient\'s symptoms. In this article we present a framework for the assessment of abusive head trauma and provide information on common presentations and injuries, as well as differential diagnoses. A strong foundational knowledge of abusive head trauma will lead to greater recognition and improved safety planning for victims of this unfortunate diagnosis.
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    文章类型: Journal Article
    这是一项多中心队列研究,旨在评估中度和重度颅脑损伤患者的放射学发现与残疾之间的关系。研究地点是SylhetMAGOsmani医学院附属医院神经外科,Sylhet妇女医学院附属医院(SWMCH)和费萨尔国王医院(KFH),Taif,KSA样本量为104,研究期为36个月(2021年7月至2022年12月)。根据放射学发现,参与者分为三个分支。不同的手臂是弥漫性创伤性脑损伤(手臂-1),局灶性创伤性脑损伤(臂-2)和两种(扩散和创伤性)类型的创伤性脑损伤(臂-3)。结果通过改良的Rankin评分(mRS)进行评估。女性的平均年龄明显更高。总体平均年龄为40.28岁。最高的数字是20岁以下年龄组,其次是41-50岁年龄组。在60岁以上的组中,参与者人数最少。改善组显着高于\'未改善\'和\'死亡\'组(p<0.00001)。改善的参与者在手臂1和手臂2中明显更高。3组的死亡率显著较高(p<0.00001)。
    This was a multicenter cohort study to evaluate the relationship between radiological findings and disability in moderate and severe head injury patients. The study places were the Neurosurgery department of Sylhet M A G Osmani Medical College Hospital, Sylhet Women\'s Medical College Hospital (SWMCH) and King Faisal Hospital (KFH), Taif, KSA. Sample size was 104 and the study period was 36 months (July 2021 to December 2022). On the basis of radiological findings the participants were divided into three arms. The different arms were diffused traumatic brain injury (arm-1), focal traumatic brain injury (arm-2) and both (diffused and traumatic) types traumatic brain injury (arm-3). Outcome was assessed by modified Rankin Score (mRS). Mean age was significantly higher in female. Overall mean age was 40.28 year. Highest number was in the below 20-year age group followed by the 41-50-year age group. Lowest number of participants was in the above 60-year group. Improved group was significantly higher than \'not improved\' and the \'died\' group (p<0.00001). Improved participants were significantly higher in the arm-1 and arm-2. Mortality was significantly higher (p<0.00001) in the arm-3 group.
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  • 文章类型: Journal Article
    尽管医学不断进步,创伤性脑损伤(TBI)仍然是全球范围内死亡和残疾的主要原因。因此,人们一直在寻求生物标志物,以允许对颅脑外伤后的患者进行非侵入性监测,有可能改善临床管理,降低并发症和死亡率。水通道蛋白(AQP),这对跨膜水运输至关重要,在这种情况下可能很重要。这项研究包括48名患者,其中27例患有急性(aSDH),21例患有慢性硬膜下血肿(cSDH)。以三个间隔从参与者那里收集血浆样本:手术前的第一个样本,第二个在15小时,第三个在手术后30小时。使用夹心ELISA技术测定AQP1,AQP2,AQP4和AQP9的血浆浓度。对所有患者在手术前后进行CT扫描。使用Spearman的非参数等级相关系数检查变量之间的相关性。水通道蛋白2水平与慢性硬膜下血肿体积和中线移位之间存在很强的相关性。然而,在急性硬膜下血肿手术前后,水通道蛋白水平(AQP1、AQP2、AQP4和AQP9)之间没有发现显著联系,慢性硬膜下血肿术后AQP1,AQP4和AQP9也没有。在慢性SDH组中,AQP2血浆浓度与术前测量的中线移位呈负相关(Spearman'sρ-0.54;p=0.017),与基线和术后30h之间的血肿体积变化呈正相关(Spearman'sρ0.627;p=0.007)。急性SDH患者水通道蛋白血浆AQP1、AQP2、AQP4和AQP9水平与血肿体积无统计学相关性。慢性硬膜下血肿体积之间存在相关性,放射学测量,和血清AQP2浓度,强调水通道蛋白作为临床生物标志物的潜力。
    Despite continuous medical advancements, traumatic brain injury (TBI) remains a leading cause of death and disability worldwide. Consequently, there is a pursuit for biomarkers that allow non-invasive monitoring of patients after cranial trauma, potentially improving clinical management and reducing complications and mortality. Aquaporins (AQPs), which are crucial for transmembrane water transport, may be significant in this context. This study included 48 patients, with 27 having acute (aSDH) and 21 having chronic subdural hematoma (cSDH). Blood plasma samples were collected from the participants at three intervals: the first sample before surgery, the second at 15 h, and the third at 30 h post-surgery. Plasma concentrations of AQP1, AQP2, AQP4, and AQP9 were determined using the sandwich ELISA technique. CT scans were performed on all patients pre- and post-surgery. Correlations between variables were examined using Spearman\'s nonparametric rank correlation coefficient. A strong correlation was found between aquaporin 2 levels and the volume of chronic subdural hematoma and midline shift. However, no significant link was found between aquaporin levels (AQP1, AQP2, AQP4, and AQP9) before and after surgery for acute subdural hematoma, nor for AQP1, AQP4, and AQP9 after surgery for chronic subdural hematoma. In the chronic SDH group, AQP2 plasma concentration negatively correlated with the midline shift measured before surgery (Spearman\'s ρ -0.54; p = 0.017) and positively with hematoma volume change between baseline and 30 h post-surgery (Spearman\'s ρ 0.627; p = 0.007). No statistically significant correlation was found between aquaporin plasma levels and hematoma volume for AQP1, AQP2, AQP4, and AQP9 in patients with acute SDH. There is a correlation between chronic subdural hematoma volume, measured radiologically, and serum AQP2 concentration, highlighting aquaporins\' potential as clinical biomarkers.
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  • 文章类型: English Abstract
    Midface fractures present a clinical challenge in otorhinolaryngology due to their often complex injury pattern and nonspecific symptoms. Precise diagnostics, including differentiated imaging procedures, are required. Interdisciplinary consultation between otorhinolaryngology, maxillofacial surgery, neurosurgery, and ophthalmology is often necessary. When selecting radiographic modalities, radiation hygiene should be taken into account. Sonography provides a radiation-free imaging alternative for fractures of the nasal framework and anterior wall of the frontal sinus. The goal of treatment is to achieve stable and symmetrical reconstruction. Depending on the injury pattern, different osteosynthesis materials, individual access routes, and various surgical procedures can be used. In clinical practice, the management of midface fractures requires a multidisciplinary, flexible, and pragmatic approach based on the fracture pattern and clinical experience.
    UNASSIGNED: Mittelgesichtsfrakturen sind aufgrund ihres häufig komplexen Verletzungsmusters und unspezifischer Symptome eine klinische Herausforderung in der HNO-Heilkunde. Eine präzise Diagnostik, einschließlich differenzierter bildgebender Verfahren, ist erforderlich. Oftmals ist eine interdisziplinäre Absprache zwischen HNO-Heilkunde, Mund‑, Kiefer‑, Gesichts(MKG)-Chirurgie, Neurochirurgie und Augenheilkunde notwendig. Bei der Auswahl der Bildgebung sollte die Strahlenhygiene berücksichtigt werden. Bei Nasengerüst- und Stirnhöhlenvorderwandfrakturen bietet die Sonographie eine strahlenfreie Alternative. Ziel der Therapie ist eine belastungsstabile und symmetrische Rekonstruktion. Je nach Verletzungsmuster können individuelle Zugangswege, unterschiedliches Osteosynthesematerial und verschiedene chirurgische Verfahren zur Anwendung kommen. Die Versorgung von Mittelgesichtsfrakturen erfordert im klinischen Alltag einen pragmatischen und interdisziplinären Ansatz, der auf klinischer Erfahrung und Flexibilität basiert.
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  • 文章类型: Journal Article
    旨在保护女童曲棍球运动员的头饰广泛可用,并允许自愿使用;但是,目前还不清楚强制使用头饰的政策如何改变这项运动,特别是关于游戏过程中的影响。因此,这项研究比较了佛罗里达州要求使用头饰(HM)的女孩高中曲棍球的影响率和游戏特征,各州没有头饰授权(NHM)。
    分析了来自189个随机选择的游戏(HM:64,NHM:125)的视频。描述性统计,影响率(IR),影响比率(IRR),影响比例(IPR),计算95%置信区间(CI)。排除1.00的相应CI的IRR和IPR被认为具有统计学意义。
    16,340影响(HM:5,821NHM:10,519;86.6影响/游戏,CI:88.6-93.3)使用曲棍球事件分析仪(LIAI)进行鉴定。大多数撞击直接撞击身体(n=16,010,98%)。少数影响直接击中玩家的头部(n=330,2%)。HM队列的头部撞击率明显高于NHM队列(IRR=2.1;95%CI=1.7-2.6)。两组中大多数头部撞击(n=271,82%)是由棍棒接触引起的。HM和NHM队列之间因棍棒接触引起的头部撞击的处罚比例没有差异(IPRIRRHM/NHM=0.98;CI=0.79-1.16)。然而,在HM队列中,由玩家接触导致处罚的头部撞击比例明显更高(IPR=1.44CI=1.17~1.54).
    这些发现表明,与NHM状态相比,强制使用头饰与在游戏过程中维持头部撞击的可能性高出两倍。HM和NHM州的大多数头部撞击都是由非法的棍棒接触引起的,不会导致罚款。
    参加具有头饰授权的州的高中女子曲棍球运动员承受头部撞击的可能性是参加没有头饰授权的州的运动员的两倍。棍棒接触仍然是女孩曲棍球中最常见的头部撞击机制,不管强制要求头饰。不管头饰是否被强制要求,大多数由棍子接触引起的头部撞击不会导致处罚。
    UNASSIGNED: Headgear designed to protect girls\' lacrosse athletes is widely available and permitted for voluntary use; however, it remains unknown how policies mandating headgear use may change the sport and, particularly regarding impacts during game-play. Therefore, this study compares the impact rates and game play characteristics of girls\' high school lacrosse in Florida which mandates headgear use (HM), with states having no headgear mandate (NHM).
    UNASSIGNED: Video from 189 randomly-selected games (HM: 64, NHM: 125) were analyzed. Descriptive statistics, Impact Rates (IR), Impact Rate Ratios (IRR), Impact Proportion Ratios (IPR), and 95% Confidence Intervals (CI) were calculated. IRRs and IPRs with corresponding CIs that excluded 1.00 were deemed statistically significant.
    UNASSIGNED: 16,340 impacts (HM:5,821 NHM: 10,519; 86.6 impacts/game, CI: 88.6-93.3) were identified using the Lacrosse Incident Analysis Instrument (LIAI). Most impacts directly struck the body (n = 16,010, 98%). A minority of impacts directly struck a player\'s head (n = 330, 2%). The rate of head impacts was significantly higher in the HM cohort than NHM cohort (IRR = 2.1; 95% CI = 1.7-2.6). Most head impacts (n = 271, 82%) were caused by stick contact in both groups. There was no difference in the proportion of penalties administered for head impacts caused by stick contact between the HM and NHM cohorts (IPR IRRHM/NHM = 0.98; CI = 0.79-1.16). However, there was a significantly greater proportion of head impacts caused by player contact that resulted in a penalty administered in the HM cohort (IPR = 1.44 CI = 1.17-1.54).
    UNASSIGNED: These findings demonstrate that mandating headgear use was associated with a two-fold greater likelihood of sustaining a head impact during game play compared to NHM states. A majority of head impacts in both HM and NHM states were caused by illegal stick contact that did not result in penalty.
    High school girls’ lacrosse athletes participating in a state with a headgear mandate was twice as likely to sustain a head impact than those participating in states without headgear mandates.Stick contact remains the most common mechanism of head impacts in girls’ lacrosse, regardless of mandating headgear.Regardless of whether headgear was or was not mandated, most head impacts caused by stick contact did not result in a penalty.
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  • 文章类型: Journal Article
    背景:在摩托车撞车的情况下,戴头盔大大降低了头部受伤的风险。世界各国都致力于推动头盔的使用,但是进展缓慢且不平衡。迫切需要大规模数据收集,以进行情况评估和干预评估。
    方法:这项研究提出了一种可扩展的,估计头盔佩戴率的低成本算法。将最先进的深度学习技术应用于从Google街景获取的图像进行对象检测,该算法有可能在全球范围内提供准确的估计。
    结果:在3995张图像样本上进行了培训,该算法取得了较高的精度。所有三个对象类别的样本外预测结果(头盔,司机,和乘客)显示的精度为0.927,召回值为0.922,50时的平均精度(mAP50)为0.956。
    结论:出色的模型性能表明,该算法能够从覆盖全球的图像源中准确估计头盔佩戴率。这种方法导致的头盔使用数据的可用性显着提高,可以加强进度跟踪,并促进全球头盔佩戴的循证决策。
    BACKGROUND: Wearing a helmet reduces the risk of head injuries substantially in the event of a motorcycle crash. Countries around the world are committed to promoting helmet use, but the progress has been slow and uneven. There is an urgent need for large-scale data collection for situation assessment and intervention evaluation.
    METHODS: This study proposes a scalable, low-cost algorithm to estimate helmet-wearing rates. Applying the state-of-the-art deep learning technique for object detection to images acquired from Google Street View, the algorithm has the potential to provide accurate estimates at the global level.
    RESULTS: Trained on a sample of 3995 images, the algorithm achieved high accuracy. The out-of-sample prediction results for all three object classes (helmets, drivers, and passengers) reveal a precision of 0.927, a recall value of 0.922, and a mean average precision at 50 (mAP50) of 0.956.
    CONCLUSIONS: The remarkable model performance suggests the algorithm\'s capacity to generate accurate estimates of helmet-wearing rates from an image source with global coverage. The significant enhancement in the availability of helmet usage data resulting from this approach could bolster progress tracking and facilitate evidence-based policymaking for helmet wearing globally.
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  • 文章类型: Journal Article
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