Craniocerebral Trauma

颅脑外伤
  • 文章类型: Journal Article
    去骨瓣减压术(DC)是一种神经外科技术,由于全球范围内头部受伤的死灰复燃,引起了人们的新兴趣。我们旨在分析在资源有限的情况下接受此手术的患者的管理质量和预后。
    这是一个前景,纵向,描述性,描述性以及Strobe之后的分析研究,在尼亚美国家医院接受DC治疗的患者持续36个月。P≤0.05被认为是显著的。
    在我们的研究中,我们收集了74例DC。平均年龄为32.04岁(10-75岁),男性占主导地位(91.89%)。DC主要在头部外伤后进行(95.95%),主要原因是道路交通事故(76%;54/71)。一入场,大多数患者表现为意识改变(95.95%)和瞳孔异常(62.16%)。脑损伤与脑部扫描之间的平均时间为31.28h,实质挫伤是最常见的病变(90.54%)。大多数患者(94.59%)接受了去骨瓣减压术。术后并发症占全部病例的71.62%,33.78%导致死亡。在幸存者中,55.10%在上次咨询时出现神经系统后遗症(27/49)。与死亡和发病风险相关的主要因素是格拉斯哥昏迷评分≤8分,入院时瞳孔异常,大脑参与的迹象的存在,还有很长的入学延迟.
    我们的研究表明,有限的资源对我们的护理的影响是适度的。未来的研究将集中在长期监测上,特别关注DC后患者的心理社会融合。
    UNASSIGNED: Decompressive craniectomy (DC) is a neurosurgical technique that is gaining renewed interest due to the worldwide resurgence of head injuries. We aimed to analyze the quality of management and prognosis of patients who underwent this surgery in the context of limited resources.
    UNASSIGNED: This was a prospective, longitudinal, descriptive, and analytical study following STROBE, lasting 36 months at the National Hospital of Niamey in patients who had undergone DC. P ≤ 0.05 was considered significant.
    UNASSIGNED: During our study, we collected 74 cases of DC. The mean age was 32.04 years (10-75 years), with male predominance (91.89%). DC was mainly performed following head trauma (95.95%), the main cause of which was road traffic accidents (76%; 54/71). On admission, most patients presented with altered consciousness (95.95%) and pupillary abnormalities (62.16%). The average time between brain damage and brain scan was 31.28 h, with parenchymal contusion being the most frequent lesion (90.54%). The majority of patients (94.59%) underwent decompressive hemicraniectomy. Postoperative complications accounted for 71.62% of all cases, with 33.78% resulting in death. Among survivors, 55.10% had neurological sequelae at the last consultation (27/49). The main factors associated with the risk of death and morbidity were a Glasgow coma score ≤8, pupillary abnormality on admission, the presence of signs of brain engagement, and a long admission delay.
    UNASSIGNED: Our study shows that the impact of limited resources on our care is moderate. Future research will concentrate on long-term monitoring, particularly focusing on the psychosocial reintegration of patients post-DC.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:本研究旨在评估与无人机(UAV)碰撞时对3岁儿童头部的生物力学影响,关注无人机质量的影响,冲击速度,和撞击方向,使用头部损伤标准(HIC)进行评估。方法:实验模拟了来自不同方向的不同质量(249、500和900g)和速度(19.0、24.0和29.0m/s)的无人机的撞击。测量每种情况的HIC值,并根据缩写的损伤量表进行分析,以确定潜在的损伤严重程度。结果:研究结果表明,无人机的质量和撞击速度对HIC值都有显著影响,较高的数字表明严重受伤的风险更大。对于重量为249克和500克的无人机,正面碰撞导致最高的HIC值;然而,对于重量为900克的无人机,最高的HIC值出现在背部撞击。此外,发现损伤风险随着速度的增加而非线性上升,尤其是重型无人机。结论:该研究强调了无人机质量和撞击速度对儿童头部受伤严重程度的关键影响。增加的质量和速度与更高的HIC值相关,表明严重受伤的可能性更大。正面撞击对轻型无人机特别危险,而重无人机的后部撞击更危险。这些发现支持需要对无人机操作参数进行严格的规定,专注于速度和质量限制,减轻儿童头部严重受伤的风险。
    Purpose: This research aimed to evaluate the biomechanical impact on a 3-year-old child\'s head during collisions with unmanned aerial vehicles (UAVs), focusing on the effects of UAV mass, impact velocity, and impact direction, using the Head Injury Criterion (HIC) for assessment. Methods: Experiments simulated impacts with UAVs of varying masses (249, 500 and 900 g) and velocities (19.0, 24.0 and 29.0 m/s) from different directions. HIC values were measured for each scenario and analyzed in relation to the Abbreviated Injury Scale to determine potential injury severity. Results: The findings showed that both the UAV\'s mass and impact velocity have a significant influence on the HIC value, with higher figures indicating a greater risk of serious injury. For the UAVs weighing 249 g and 500 g, frontal impacts resulted in the highest HIC values; however, for the UAV weighing 900 g, the highest HIC value occurred for the back hit. Moreover, injury risk was found to escalate non-linearly with increased velocity, especially for heavier UAVs. Conclusions: The study emphasizes the critical influence of UAV mass and impact velocity on the severity of head injuries in children. Increased mass and velocity correlated with higher HIC values, indicating a greater likelihood of severe injury. Frontal impacts were particularly hazardous for lighter UAVs, while rear impacts were more dangerous for heavier UAVs. These findings support the need for stringent regulations on UAV operational parameters, focusing on speed and mass limitations, to mitigate the risk of severe head injuries in children.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • DOI:
    文章类型: Journal Article
    这是一项多中心队列研究,旨在评估中度和重度颅脑损伤患者的放射学发现与残疾之间的关系。研究地点是SylhetMAGOsmani医学院附属医院神经外科,Sylhet妇女医学院附属医院(SWMCH)和费萨尔国王医院(KFH),Taif,KSA样本量为104,研究期为36个月(2021年7月至2022年12月)。根据放射学发现,参与者分为三个分支。不同的手臂是弥漫性创伤性脑损伤(手臂-1),局灶性创伤性脑损伤(臂-2)和两种(扩散和创伤性)类型的创伤性脑损伤(臂-3)。结果通过改良的Rankin评分(mRS)进行评估。女性的平均年龄明显更高。总体平均年龄为40.28岁。最高的数字是20岁以下年龄组,其次是41-50岁年龄组。在60岁以上的组中,参与者人数最少。改善组显着高于\'未改善\'和\'死亡\'组(p<0.00001)。改善的参与者在手臂1和手臂2中明显更高。3组的死亡率显著较高(p<0.00001)。
    This was a multicenter cohort study to evaluate the relationship between radiological findings and disability in moderate and severe head injury patients. The study places were the Neurosurgery department of Sylhet M A G Osmani Medical College Hospital, Sylhet Women\'s Medical College Hospital (SWMCH) and King Faisal Hospital (KFH), Taif, KSA. Sample size was 104 and the study period was 36 months (July 2021 to December 2022). On the basis of radiological findings the participants were divided into three arms. The different arms were diffused traumatic brain injury (arm-1), focal traumatic brain injury (arm-2) and both (diffused and traumatic) types traumatic brain injury (arm-3). Outcome was assessed by modified Rankin Score (mRS). Mean age was significantly higher in female. Overall mean age was 40.28 year. Highest number was in the below 20-year age group followed by the 41-50-year age group. Lowest number of participants was in the above 60-year group. Improved group was significantly higher than \'not improved\' and the \'died\' group (p<0.00001). Improved participants were significantly higher in the arm-1 and arm-2. Mortality was significantly higher (p<0.00001) in the arm-3 group.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    探讨头皮电针结合康复训练治疗颅脑损伤后失语症的临床疗效,并分析其对患者语言功能和生活质量的影响。我院随机选取2020年3月至2022年3月收治的100例颅脑损伤所致失语症患者作为实验对象,将其分为对照组和实验组,每组50例。对照组进行一般康复训练,实验组进行头皮电针结合康复训练,比较其简易精神状态检查成绩,日常生活中的交际活动得分,中国的失语症的电池成绩,生活质量分数,非精神病设置中的精神状态量表得分,美国国立卫生研究院卒中量表评分,有效利率,患者满意度,和不良反应发生率。在组间比较中,实验组患者的简易精神状态检查评分明显高于对照组,日常生活中的交际活动得分,中国的失语症的电池成绩,生活质量分数,有效利率,和满意,在非精神病环境中,精神状态量表得分显着降低,美国国立卫生研究院卒中量表评分和不良反应发生率,具有统计学意义(所有情况下P<0.05)。头皮电针与康复训练联合治疗可有效改善颅脑损伤后失语症患者的语言功能和生活质量,显著提高治疗效果。
    To explore the clinical efficacy of scalp electroacupuncture combined with rehabilitation training for aphasia after head injury, and analyze its effect on patients\' language function and quality of life. Our hospital randomly enrolled 100 aphasia patients caused by head injury treated from March 2020 to March 2022 as the experimental object and divided them into the control group and experimental group, with 50 cases in each group. The general rehabilitation training was performed to the control group and the scalp electroacupuncture combined with rehabilitation training was performed to the experimental group to compare their mini-mental state examination scores, communicative activities in daily living scores, aphasia battery of Chinese scores, quality of life scores, mental status scale in nonpsychiatric settings scores, National Institutes of Health Stroke Scale scores, effective rates, satisfaction of patients, and adverse reaction rates. In the between-group comparison, the patients in the experimental group had significantly higher mini-mental state examination scores, communicative activities in daily living scores, aphasia battery of Chinese scores, quality of life scores, effective rates, and satisfaction, and significantly lower mental status scale in nonpsychiatric settings scores, National Institutes of Health Stroke Scale scores and adverse reaction rates, which was statistically significant (P < .05 in all cases). The combination treatment of scalp electroacupuncture and rehabilitation training can effectively improve the language function and quality of life of patients with aphasia after head injury and remarkably enhance the treatment effect.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:创伤性脑损伤(TBI)是院前环境中的常见表现。目前,护理人员通常不会使用工具来识别可能留在现场或被送往当地医院而不是主要创伤中心的低风险患者。制定了加拿大CT头目规则(CHR),以指导医院CT成像的使用。尚未在院前环境中进行评估。我们的目标是通过评估对患者和护理人员实施CCHR的可行性和可接受性来解决这一差距,以及对其使用进行全面临床试验的可行性。
    方法:我们将招募患有轻度TBI后被救护车送往急诊科(ED)的成年患者。护理人员将前瞻性地收集CCHR的数据。所有患者将被送往急诊室,在延期同意的情况下,治疗临床医生将重新评估CCHR,对护理人员的解释视而不见。主要临床结果将是神经外科重要的TBI。可行性结果包括招聘和流失率。我们将使用渥太华决策规则工具评估CHR对护理人员的可接受性。CHR的观察者间可靠性将在护理人员和ED中的治疗临床医生之间进行评估。参与的护理人员和患者将被邀请参加半结构化访谈,以探索试验过程和促进者的可接受性以及在实践中使用CHR的障碍。数据将按主题进行分析。我们预计在6个月内招募约100名患者。
    背景:本研究获得了健康研究机构和研究伦理委员会的批准(REC参考:22/NW/0358)。结果将发表在同行评审的期刊上,在会议上提出,并将被纳入博士论文。
    背景:ISRCTN92566288。
    BACKGROUND: Traumatic brain injury (TBI) is a common presentation in the prehospital environment. At present, paramedics do not routinely use tools to identify low-risk patients who could be left at scene or taken to a local hospital rather than a major trauma centre. The Canadian CT Head Rule (CCHR) was developed to guide the use of CT imaging in hospital. It has not been evaluated in the prehospital setting. We aim to address this gap by evaluating the feasibility and acceptability of implementing the CCHR to patients and paramedics, and the feasibility of conducting a full-scale clinical trial of its use.
    METHODS: We will recruit adult patients who are being transported to an emergency department (ED) by ambulance after suffering a mild TBI. Paramedics will prospectively collect data for the CCHR. All patients will be transported to the ED, where deferred consent will be taken and the treating clinician will reassess the CCHR, blinded to paramedic interpretation. The primary clinical outcome will be neurosurgically significant TBI. Feasibility outcomes include recruitment and attrition rates. We will assess acceptability of the CCHR to paramedics using the Ottawa Acceptability of Decision Rules Instrument. Interobserver reliability of the CCHR will be assessed between paramedics and the treating clinician in the ED. Participating paramedics and patients will be invited to participate in semistructured interviews to explore the acceptability of trial processes and facilitators and barriers to the use of the CCHR in practice. Data will be analysed thematically. We anticipate recruiting approximately 100 patients over 6 months.
    BACKGROUND: This study was approved by the Health Research Authority and the Research Ethics Committee (REC reference: 22/NW/0358). The results will be published in a peer-reviewed journal, presented at conferences and will be incorporated into a doctoral thesis.
    BACKGROUND: ISRCTN92566288.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:为了描述频率,type,以及长道速滑中健康问题的严重性,以告知伤害预防策略。
    方法:我们前瞻性地收集了2019/2020赛季期间84名训练有素的15-21岁荷兰运动员的每周健康和运动暴露数据,使用奥斯陆运动创伤研究中心关于健康问题的问卷和培训师的文件。我们将健康问题分类为急性或重复的损伤或疾病机制,并计算发生率(每1000个运动暴露小时),与受影响的身体区域相关的每周患病率和负担(每1000个运动暴露小时的时间损失天数)。
    结果:我们记录了283个健康问题(187人受伤,96种疾病),健康问题的平均每周患病率为30.5%(95%CI28.7%至32.2%)。急性机制损伤的发生率为2.0/1000小时(95%CI1.5至2.5),疾病的发生率为3.2/1000小时(95%CI2.6至3.9)。对于头部的急性机制损伤,肩部和腰骶部的损伤负担最高,为5.6(95%CI4.8~6.5),2.9(95%CI2.3至3.5)和2.2(95%CI1.7至2.8)天的时间损失/1000小时,分别。对于重复性机制损伤,膝盖,胸椎,小腿和腰骶部的损伤负担最高,11.0(95%CI9.8至12.2),6.8(95%CI5.9至7.7),3.9(95%CI3.2至4.6)和2.5(95%CI1.9至3.1)天的时间损失/1000小时,分别。
    结论:我们的研究表明,速滑运动中急性和重复机制损伤的患病率很高。这些结果可以指导未来的研究和损伤预防的重点。
    OBJECTIVE: To describe the frequency, type, and severity of health problems in long-track speed skating to inform injury prevention strategies.
    METHODS: We prospectively collected weekly health and sport exposure data on 84 highly trained Dutch athletes aged 15-21 years during the 2019/2020 season using the Oslo Sports Trauma Research Centre questionnaire on Health Problems and the trainers\' documentation. We categorised health problems into acute or repetitive mechanisms of injury or illness and calculated incidences (per 1000 sports exposure hours), weekly prevalence and burden (days of time loss per 1000 sports exposure hours) related to the affected body region.
    RESULTS: We registered 283 health problems (187 injuries, 96 illnesses), yielding an average weekly prevalence of health problems of 30.5% (95% CI 28.7% to 32.2%). Incidence rates were 2.0/1000 hours for acute mechanism injuries (95% CI 1.5 to 2.5) and 3.2/1000 hours for illnesses (95% CI 2.6 to 3.9). For acute mechanism injuries the head, shoulder and lumbosacral region had the highest injury burden of 5.6 (95% CI 4.8 to 6.5), 2.9 (95% CI 2.3 to 3.5) and 2.2 (95% CI 1.7 to 2.8) days of time loss/1000 hours, respectively. For repetitive mechanism injuries, the knee, thoracic spine, lower leg and lumbosacral region had the highest injury burden, with 11.0 (95% CI 9.8 to 12.2), 6.8 (95% CI 5.9 to 7.7), 3.9 (95% CI 3.2 to 4.6) and 2.5 (95% CI 1.9 to 3.1) days of time loss/1000 hours, respectively.
    CONCLUSIONS: Our study demonstrated a high prevalence of acute and repetitive mechanism injuries in speed skating. These results can guide future research and priorities for injury prevention.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:斯堪的纳维亚神经委员会的现行指南要求对头部创伤患者的抗凝药进行24小时观察,即使初始头部CT扫描正常,作为不错过迟发性颅内出血的手段。这项研究旨在评估患病率,和诊断时间,口服抗凝剂治疗的头部创伤患者的临床相关迟发性颅内出血。
    方法:利用索恩地区急诊科的全面两年数据,为130万人口服务,这项研究的重点是成人头部创伤患者口服抗凝剂。我们在30天内发现了颅内出血,将迟发性颅内出血定义为在最初的CT头颅扫描中不明显的出血。如果与死亡率相关,这些病例被进一步定义为临床相关。任何重症监护室入院,或者神经外科手术.
    结果:在纳入的2,362例颅脑损伤病例中(中位年龄84岁,直接作用口服抗凝剂占56%),5例发生迟发性颅内出血.这五例病例均未接受神经外科手术,也未进入重症监护病房。只有2例(0.08%,95%置信区间[0.01-0.3%])被归类为临床相关,涉及82岁和87岁患者的硬膜下血肿,后来两人都死了。这些迟发性颅内出血的诊断是在最初向急诊科就诊后的4天和7天进行的。
    结论:在头部外伤患者中,关于口服抗凝,发现临床相关的迟发性颅内出血的发生率不到千分之一,检测发生在初次报告后四天或更晚。这挑战了斯堪的纳维亚神经创伤委员会指南建议的24小时观察期的有效性,建议需要重新评估这些指南,以优化护理和资源分配。
    背景:这是一项回顾性队列研究,不包括任何干预,因此未注册。
    BACKGROUND: Current guidelines from Scandinavian Neuro Committee mandate a 24-hour observation for head trauma patients on anticoagulants, even with normal initial head CT scans, as a means not to miss delayed intracranial hemorrhages. This study aimed to assess the prevalence, and time to diagnosis, of clinically relevant delayed intracranial hemorrhage in head trauma patients treated with oral anticoagulants.
    METHODS: Utilizing comprehensive two-year data from Region Skåne\'s emergency departments, which serve a population of 1.3 million inhabitants, this study focused on adult head trauma patients prescribed oral anticoagulants. We identified those with intracranial hemorrhage within 30 days, defining delayed intracranial hemorrhage as a bleeding not apparent on their initial CT head scan. These cases were further defined as clinically relevant if associated with mortality, any intensive care unit admission, or neurosurgery.
    RESULTS: Out of the included 2,362 head injury cases (median age 84, 56% on a direct acting oral anticoagulant), five developed delayed intracranial hemorrhages. None of these five cases underwent neurosurgery nor were admitted to an intensive care unit. Only two cases (0.08%, 95% confidence interval [0.01-0.3%]) were classified as clinically relevant, involving subdural hematomas in patients aged 82 and 87 years, who both subsequently died. The diagnosis of these delayed intracranial hemorrhages was made at 4 and 7 days following initial presentation to the emergency department.
    CONCLUSIONS: In patients with head trauma, on oral anticoagulation, the incidence of clinically relevant delayed intracranial hemorrhage was found to be less than one in a thousand, with detection occurring four days or later after initial presentation. This challenges the effectiveness of the 24-hour observation period recommended by the Scandinavian Neurotrauma Committee guidelines, suggesting a need to reassess these guidelines to optimise care and resource allocation.
    BACKGROUND: This is a retrospective cohort study, does not include any intervention, and has therefore not been registered.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    2016年头部创伤的年龄标准化发病率为全球每10万人中369人。西太平洋地区,包括日本,发病率最高。本研究旨在提取颅内损伤(S06)和发病率和死亡率的外部原因(V01-Y89)的ICD-10代码数据,分析它们的特点和相互关系,并有助于这些疾病的预防,治疗,和预后。日本政府公布的颅内损伤按损伤类型和外因类型的死亡人数采用JoinPoint进行统计分析,使用JMP软件进行单变量分布和多变量相关。从1999年至2021年,由于颅内损伤导致的死亡人数呈下降趋势:年龄≥65岁的人群中,颅内损伤导致的死亡率较高。相反,在≤14岁的人群中,颅内损伤死亡率较低.在颅内损伤的死亡中,弥漫性脑损伤和外伤性硬膜下出血的死亡率更为常见.在颅内损伤的外部原因死亡中,跌倒死亡,运输事故,其他不可预见的事故更为常见。在2011年东日本大地震期间,颅内损伤导致的死亡率显着增加。对于某些年龄组和性别,死亡率与外伤性硬膜下出血和外伤性蛛网膜下腔出血之间存在显著的负相关,故意自我伤害和攻击,以及因跌倒引起的弥漫性脑损伤和局灶性脑损伤。我们认为,这项研究中提供的数据将有助于预防和治疗颅内损伤以及制定减少颅内损伤的管理措施。
    The age-standardized incidence of head trauma in 2016 was 369 per 100,000 people worldwide. The Western Pacific region, including Japan, had the highest incidence. This study aimed to extract ICD-10 code data for intracranial injury (S06) and external causes of morbidity and mortality (V01-Y89), analyze their characteristics and interrelationships, and contribute to these diseases\' prevention, treatment, and prognosis. The number of deaths according to injury type and external cause type of intracranial injury published by the Japanese government was statistically analyzed using JoinPoint, and univariate distribution and multivariate correlation were conducted using JMP Software. From 1999-2021, there was a downward trend in the number of deaths because of intracranial injuries: mortality from intracranial injuries was higher among those aged ≥65 years. Conversely, mortality from intracranial injuries was lower among those aged ≤14 years. Among deaths from intracranial injury, mortality from diffuse brain injury and traumatic subdural hemorrhage was more common. Among deaths from external causes of intracranial injury, mortality from falls, transport accidents, and other unforeseen accidents was more common. Mortality because of intracranial injuries increased significantly during the 2011 Great East Japan Earthquake. For some age groups and sexes, there were significant inverse correlations of mortality with traumatic subdural hemorrhage and traumatic subarachnoid hemorrhage for transport accidents, intentional self-harm and assault, and diffuse brain injury and focal brain injury for falls. We believe that the data presented in this study will be useful for preventing and treating intracranial injuries and for developing administrative measures to reduce intracranial injuries.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Multicenter Study
    背景:由儿科急诊护理应用研究网络(PECARN)得出的腹内损伤和创伤性脑损伤预测规则旨在减少腹部和头部创伤儿童的CT不当使用,分别。我们旨在验证这些预测规则,以应对腹部钝性或轻微头部外伤的急诊儿童。
    方法:对于本前瞻性验证研究,我们招募了18岁以下的儿童和青少年,向萨克拉曼多(CA)的六个急诊科就诊,达拉斯(TX),休斯顿(TX),圣地亚哥(CA),洛杉矶(CA),奥克兰(CA)2016年12月27日至2021年9月1日之间的美国。我们排除了怀孕或先前存在神经系统疾病的患者,穿透性创伤,在抵达前24小时受伤,转移前的CT或MRI,或者高度怀疑非意外创伤。出现钝性腹部创伤的儿童被纳入腹部创伤队列,将有轻微头部创伤的儿童纳入两个年龄隔离的轻微头部创伤队列中的一个(小于2岁vs大于2岁).入学儿童在急诊科接受了临床检查,和CT扫描由主治临床医生决定。在看到CT结果之前,根据相关PECARN预测规则的变量对所有入组儿童进行评估。腹部创伤队列中感兴趣的主要结果是接受急性干预的腹内损伤(治疗性剖腹手术,血管造影栓塞,输血,用于胰腺或胃肠道损伤的静脉输液≥2天,或因腹内损伤而死亡)。在年龄隔离的轻微头部创伤队列中,感兴趣的主要结果是临床上重要的创伤性脑损伤(神经外科,插管>24小时用于创伤性脑损伤,或因持续症状和CT证实的创伤性脑损伤住院≥2晚;或因创伤性脑损伤死亡)。
    结果:纳入7542例腹部钝性外伤儿童和19999例头部轻微外伤儿童。腹内损伤规则的敏感性为100·0%(95%CI98·0-100·0;145例接受急性干预的腹内损伤患者中的145例正确测试)和阴性预测值(NPV)为100·0%(95%CI99·9-100·0;3488例未接受急性干预的腹内损伤患者中的3488例正确测试)。2岁以下儿童的创伤性脑损伤规则对临床重要的创伤性脑损伤的敏感性为100·0%(93·1-100·0;42个中的42个),NPV为100·0%;99·9-100·0;2940个中的2940个),而2岁及以上儿童的创伤性脑损伤规则的敏感性为98·8%(95·8-99·9;170中的168),NPV为100·0%(99·9-100·0;6017中的6015)。根据创伤性脑损伤规则错误分类的两个孩子被送进医院观察,但不需要神经外科手术。
    结论:以高度的准确性验证了PECARN腹内损伤和创伤性脑损伤的规律。因此,它们在儿科急诊科的实施可以被认为是一种安全策略,可以最大程度地减少需要高质量护理腹部或头部创伤的儿童的不适当CT使用。
    背景:EuniceKennedyShriver国家儿童健康与人类发展研究所。
    BACKGROUND: The intra-abdominal injury and traumatic brain injury prediction rules derived by the Pediatric Emergency Care Applied Research Network (PECARN) were designed to reduce inappropriate use of CT in children with abdominal and head trauma, respectively. We aimed to validate these prediction rules for children presenting to emergency departments with blunt abdominal or minor head trauma.
    METHODS: For this prospective validation study, we enrolled children and adolescents younger than 18 years presenting to six emergency departments in Sacramento (CA), Dallas (TX), Houston (TX), San Diego (CA), Los Angeles (CA), and Oakland (CA), USA between Dec 27, 2016, and Sept 1, 2021. We excluded patients who were pregnant or had pre-existing neurological disorders preventing examination, penetrating trauma, injuries more than 24 h before arrival, CT or MRI before transfer, or high suspicion of non-accidental trauma. Children presenting with blunt abdominal trauma were enrolled into an abdominal trauma cohort, and children with minor head trauma were enrolled into one of two age-segregated minor head trauma cohorts (younger than 2 years vs aged 2 years and older). Enrolled children were clinically examined in the emergency department, and CT scans were obtained at the attending clinician\'s discretion. All enrolled children were evaluated against the variables of the pertinent PECARN prediction rule before CT results were seen. The primary outcome of interest in the abdominal trauma cohort was intra-abdominal injury undergoing acute intervention (therapeutic laparotomy, angiographic embolisation, blood transfusion, intravenous fluid for ≥2 days for pancreatic or gastrointestinal injuries, or death from intra-abdominal injury). In the age-segregated minor head trauma cohorts, the primary outcome of interest was clinically important traumatic brain injury (neurosurgery, intubation for >24 h for traumatic brain injury, or hospital admission ≥2 nights for ongoing symptoms and CT-confirmed traumatic brain injury; or death from traumatic brain injury).
    RESULTS: 7542 children with blunt abdominal trauma and 19 999 children with minor head trauma were enrolled. The intra-abdominal injury rule had a sensitivity of 100·0% (95% CI 98·0-100·0; correct test for 145 of 145 patients with intra-abdominal injury undergoing acute intervention) and a negative predictive value (NPV) of 100·0% (95% CI 99·9-100·0; correct test for 3488 of 3488 patients without intra-abdominal injuries undergoing acute intervention). The traumatic brain injury rule for children younger than 2 years had a sensitivity of 100·0% (93·1-100·0; 42 of 42) for clinically important traumatic brain injuries and an NPV of 100·0%; 99·9-100·0; 2940 of 2940), whereas the traumatic brain injury rule for children aged 2 years and older had a sensitivity of 98·8% (95·8-99·9; 168 of 170) and an NPV of 100·0% (99·9-100·0; 6015 of 6017). The two children who were misclassified by the traumatic brain injury rule were admitted to hospital for observation but did not need neurosurgery.
    CONCLUSIONS: The PECARN intra-abdominal injury and traumatic brain injury rules were validated with a high degree of accuracy. Their implementation in paediatric emergency departments can therefore be considered a safe strategy to minimise inappropriate CT use in children needing high-quality care for abdominal or head trauma.
    BACKGROUND: The Eunice Kennedy Shriver National Institute of Child Health and Human Development.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Clinical Study
    背景:轻度创伤性脑损伤在儿童中很常见,准确识别需要紧急医疗干预的患者可能具有挑战性。斯堪的纳维亚儿童轻度和中度头部创伤管理指南,斯堪的纳维亚神经创伤委员会指南2016(SNC16),旨在帮助斯堪的纳维亚急诊科(ED)的风险分层和决策。本指南已得到外部验证,结果令人鼓舞,但在广泛的临床实施之前,需要在预期的医疗保健系统中进行内部验证.
    目的:我们旨在验证SNC16的诊断准确性,以预测患有钝性颅脑外伤的儿科患者的临床重要颅内损伤(CIII),在瑞典和挪威的ED中评估。
    方法:这是一个前瞻性的,务实,观察性队列研究。头部钝性外伤的儿童(0-17岁),在16家参与医院中的1家医院中,在受伤后24小时内进行了9-15的格拉斯哥昏迷评分,有资格列入。根据每个医院的临床管理常规对纳入的患者进行评估和管理。由检查医生以电子病例报告形式收集用于风险分层的数据元素。主要结果定义为损伤后1周内的CIII。重要的次要结果包括外伤性CT检查结果,神经外科手术和3个月的结果。SNC16预测终点的诊断准确性将通过点估计和95%CIs进行评估,特异性,似然比,阴性预测值和阳性预测值。
    背景:该研究得到了瑞典和挪威伦理委员会的批准。该验证的结果将在科学期刊上发表,如果发现SNC16安全有效,将遵循量身定制的开发和实施过程。
    背景:NCT05964764。
    BACKGROUND: Mild traumatic brain injury is common in children and it can be challenging to accurately identify those in need of urgent medical intervention. The Scandinavian guidelines for management of minor and moderate head trauma in children, the Scandinavian Neurotrauma Committee guideline 2016 (SNC16), were developed to aid in risk stratification and decision-making in Scandinavian emergency departments (EDs). This guideline has been validated externally with encouraging results, but internal validation in the intended healthcare system is warranted prior to broad clinical implementation.
    OBJECTIVE: We aim to validate the diagnostic accuracy of the SNC16 to predict clinically important intracranial injuries (CIII) in paediatric patients suffering from blunt head trauma, assessed in EDs in Sweden and Norway.
    METHODS: This is a prospective, pragmatic, observational cohort study. Children (aged 0-17 years) with blunt head trauma, presenting with a Glasgow Coma Scale of 9-15 within 24 hours postinjury at an ED in 1 of the 16 participating hospitals, are eligible for inclusion. Included patients are assessed and managed according to the clinical management routines of each hospital. Data elements for risk stratification are collected in an electronic case report form by the examining doctor. The primary outcome is defined as CIII within 1 week of injury. Secondary outcomes of importance include traumatic CT findings, neurosurgery and 3-month outcome. Diagnostic accuracy of the SNC16 to predict endpoints will be assessed by point estimate and 95% CIs for sensitivity, specificity, likelihood ratio, negative predictive value and positive predictive value.
    BACKGROUND: The study is approved by the ethical board in both Sweden and Norway. Results from this validation will be published in scientific journals, and a tailored development and implementation process will follow if the SNC16 is found safe and effective.
    BACKGROUND: NCT05964764.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

公众号