Core temperature

堆芯温度
  • 文章类型: Journal Article
    如果发生严重的职业性热相关疾病,护理人员援助可能无法立即获得。工人的生存可能取决于他们的同事获得有效的基于现场的冷却方式。一种声称在基于现场的设置中实用的冷却方法是冰巾方法。
    本案例研究评估了冰巾方法在工业环境中的实用性,其中使用标准包括成本效益,便携性,可扩展性,并由一名工人在紧急情况下实施。
    本案例研究描述了在等待护理人员时使用冰巾方法的紧急应用,对于一名在远程工作现场遭受疑似劳力中暑的工人。
    冰巾能够被运送到偏远的现场,并由一名工人在可能危及生命的紧急情况的压力下成功应用。
    冰巾方法具有成本效益,可扩展,可运输,并迅速应用于基于现场的紧急情况。本案例研究证明了组织评估其热相关风险的重要性,并根据其独特设置的有效性和实用性来确定控件。
    UNASSIGNED: In the event of a severe occupational heat-related illness, paramedic assistance may not be immediately available. A worker\'s survival may depend on their co-workers access to efficacious field-based cooling modalities. One cooling method that has been claimed to be practical in field-based settings is the ice towel method.
    UNASSIGNED: This case study assessed the practicality of the ice towel method in an industrial setting, where criteria for use include cost effectiveness, portability, scalability, and implementation by a single worker under the stress of an emergency.
    UNASSIGNED: This case study describes the emergency application of the ice towel method while awaiting paramedics, for a worker suffering suspected exertional heat stroke on a remote job site.
    UNASSIGNED: Ice towels were able to be transported to a remote field site and applied successfully by a single worker under the stress of a potentially life-threatening emergency.
    UNASSIGNED: The ice towel method was cost effective, scalable, transportable, and rapidly applied in a field-based emergency. This case study demonstrates the importance of organizations assessing their heat-related risks, and determining controls based upon their efficacy and practicality for their unique setting.
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  • 文章类型: Journal Article
    最近的热浪强调了在运动环境中进行准确和连续的核心温度(TCORE)监测的重要性。例如,环境热应激下体育锻炼引起的TCORE升高会增加热疾病的风险。因此,使用有效和可重复的设备对于确保安全的运动实践至关重要。在这项研究中,我们评估了CaleraResearchSensor(CRS)在炎热环境下进行自行车运动时估计男性和女性参与者TCORE的有效性和可重复性.七名男性(年龄:36.2±10.1岁)和八名女性自行车手(年龄:30.1±5.0岁)在干球温度为32°C和相对湿度为60%的条件下进行了两次相同的自行车试验。该方案包括最初的10分钟休息,然后是60分钟的运动,包括20%的10分钟,25分钟,55%,在最大有氧能力的75%下25分钟,运动后再恢复25分钟。使用胃肠胶囊(TGi)和CRS(TSENSOR)每分钟同时记录TCORE。进行Bland-Altman分析以计算偏倚,一致上限(LCS)和下限(LCI),和95%置信区间(95CI)。两个装置之间的最大可接受差异预定为±0.4°C。混合线性模型用于评估两个测量系统之间的成对差异,考虑到参与者,试验,环境条件为随机效应,循环阶段为固定效应。当分析来自整个实验的数据时,记录到0.98的类内相关系数(ICC)。非显著偏差值为0.01°C,LCS为0.38°C,LCI为-0.35°C,发现95%的CI为±0.36°C。当根据参与者的性别分析数据时,男女的CRS重现性均较高:男性和女性的ICC值为0.98和0.99,分别。CI95%在男性实验中为0.35°C,女性为0.37°C,从而落在可接受的差异范围内。因此,CRS被认为是有效的(与TGi相比),并且可以在高温下各种强度的自行车运动中估计两种性别的TCORE。
    Recent heatwaves have highlighted the importance of accurate and continuous core temperature (TCORE) monitoring in sports settings. For example, accentuated rises in TCORE caused by physical exercises under environmental heat stress increase the risk of heat illnesses. Thus, using valid and reproducible devices is essential to ensure safe sports practice. In this study, we assessed the validity and reproducibility of the Calera Research Sensor (CRS) in estimating the TCORE of male and female participants during cycling exercise in a hot environment. Seven male (age: 36.2 ± 10.1 years) and eight female cyclists (age: 30.1 ± 5.0 years) underwent two identical cycling trials in a dry-bulb temperature of 32 °C and relative humidity of 60%. The protocol consisted of an initial 10-min rest followed by a 60-min exercise comprising 10 min at 20%, 25 min at 55%, and 25 min at 75% of maximal aerobic power, and an additional 25 min of post-exercise recovery. TCORE was recorded simultaneously every minute using a gastrointestinal capsule (TGi) and the CRS (TSENSOR). Bland-Altman analysis was performed to calculate bias, upper (LCS) and lower (LCI) concordance limits, and the 95% confidence interval (95%CI). The maximum acceptable difference between the two devices was predetermined at ±0.4 °C. A mixed linear model was used to assess the paired differences between the two measurement systems, considering the participants, trials, and environmental conditions as random effects and the cycling stages as fixed effects. An intra-class correlation coefficient (ICC) of 0.98 was recorded when analyzing data from the entire experiment. A non-significant bias value of 0.01 °C, LCS of 0.38 °C, LCI of -0.35 °C, and CI95% of ±0.36 °C were found. When analyzing data according to the participants\' sex, CRS reproducibility was high in both sexes: ICC values of 0.98 and 0.99 were reported for males and females, respectively. CI95% was 0.35 °C in experiments with males and 0.37 °C with females, thereby falling within the acceptable margin of difference. Therefore, CRS was considered valid (compared to TGi) and reproducible in estimating TCORE in both sexes at various intensities of cycling exercise in the heat.
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  • 文章类型: Journal Article
    产热是众所周知的,但是冷水浸泡(CWI)之间的关系,CWI后复温和相关的生理变化没有。这项研究调查了肌肉和全身氧合,心肺和血液动力学反应,以及CWI期间和之后的胃肠道温度。21名健康男性随机完成2个方案。两种方案都包括48分钟的热循环锻炼,然后是3个恢复期(R1-R3)。但它们的R2不同.R1在环境室温下在物理治疗台上以被动半坐姿持续20分钟。根据协议,R2在环境条件下(R2_AMB)或在CWI条件下在10°C下持续15分钟,直至Ii骨(R2_CWI)。R3在AMB处持续40分钟,同时有利于在R2_CWI之后复温。这之后是10分钟的循环。与R2_AMB相比,由于产热,R2_CWI在未浸入的身体部位中处于较高的V•O2(7.16(2.15)与4.83(1.62)ml。min-1.kg-1)和下股动脉血流(475(165)与704(257)ml。min-1)(p<0.001)。只有在CWI之后,R3显示了一个渐进的减少在肌和腓肠肌内侧O2饱和度,34分钟后显著(p<0.001)。由于血流与AMB方案没有区别,这表明身体浸入部分的局部产热。在CWI之后,与AMB相比,恢复循环时的胃肠道温度较低(36.31(0.45)与37.30(0.49)°C,p<0.001)表明肌肉热生成不完全。总之,CWI后的复温期是非线性的,代谢昂贵.沉浸和复温应被视为连续体,而不是单独的事件。
    Thermogenesis is well understood, but the relationships between cold water immersion (CWI), the post-CWI rewarming and the associated physiological changes are not. This study investigated muscle and systemic oxygenation, cardiorespiratory and hemodynamic responses, and gastrointestinal temperature during and after CWI. 21 healthy men completed randomly 2 protocols. Both protocols consisted of a 48 minutes heating cycling exercise followed by 3 recovery periods (R1-R3), but they differed in R2. R1 lasted 20 minutes in a passive semi-seated position on a physiotherapy table at ambient room temperature. Depending on the protocol, R2 lasted 15 minutes at either ambient condition (R2_AMB) or in a CWI condition at 10°C up to the iliac crest (R2_CWI). R3 lasted 40 minutes at AMB while favoring rewarming after R2_CWI. This was followed by 10 minutes of cycling. Compared to R2_AMB, R2_CWI ended at higher V ˙ O2 in the non-immersed body part due to thermogenesis (7.16(2.15) vs. 4.83(1.62) ml.min-1.kg-1) and lower femoral artery blood flow (475(165) vs. 704(257) ml.min-1) (p < 0.001). Only after CWI, R3 showed a progressive decrease in vastus and gastrocnemius medialis O2 saturation, significant after 34 minutes (p < 0.001). As blood flow did not differ from the AMB protocol, this indicated local thermogenesis in the immersed part of the body. After CWI, a lower gastrointestinal temperature on resumption of cycling compared to AMB (36.31(0.45) vs. 37.30(0.49) °C, p < 0.001) indicated incomplete muscle thermogenesis. In conclusion, the rewarming period after CWI was non-linear and metabolically costly. Immersion and rewarming should be considered as a continuum rather than separate events.
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  • 文章类型: Journal Article
    已知季节性适应会导致可以提高耐热性的适应。烧伤手术的工作人员暴露于热应力条件下,季节性适应可能会改善手术期间的热效应反应。因此,这项研究的目的是评估在夏季和冬季进行烧伤手术的工作人员的生理和知觉反应,以确定他们是否适应加热手术室。在热中性进行的烧伤手术中,八名工作人员的生理和知觉反应进行了比较(CON:24.1±1.2°C,45±7%相对湿度[RH])并加热(HOT:31.3±1.6°C,44±7%RH)手术室,在夏天和冬天。评估的生理参数包括核心温度,心率,总出汗量,出汗率,和尿比重。感知反应包括热感觉和舒适度的评级。在夏天,CON与冬季CON相比,基线(85±15bpmVS94±18bpm),平均值(84±16bpmVS93±18bpm),和峰值HR(94±17bpmVS105±19bpm)较低(p<0.05),而在两种情况下,不同季节的核心温度没有差异(p>0.05)。在热,夏季(15±3)的不适评分高于冬季(13±3;p>0.05),但季节之间的热感觉和出汗率等级相似(p>0.05)。西澳大利亚州的烧伤手术团队可以获得一些因季节性适应而导致的生理适应,但不是全部。这很可能是由于夏季室外热暴露量低于要求,诱导所有的生理和知觉适应。
    Seasonal acclimatization is known to result in adaptations that can improve heat tolerance. Staff who operate on burn injuries are exposed to thermally stressful conditions and seasonal acclimatization may improve their thermoeffector responses during surgery. Therefore, the aim of this study was to assess the physiological and perceptual responses of staff who operate on burn injuries during summer and winter, to determine whether they become acclimatized to the heated operating theater. Eight staff members had physiological and perceptual responses compared during burn surgeries conducted in thermoneutral (CON: 24.1 ± 1.2°C, 45 ± 7% relative humidity [RH]) and heated (HOT: 31.3 ± 1.6°C, 44 ± 7% RH) operating theaters, in summer and winter. Physiological parameters that were assessed included core temperature, heart rate, total sweat loss, sweat rate, and urinary specific gravity. Perceptual responses included ratings of thermal sensation and comfort. In summer, CON compared to winter CON, baseline (85 ± 15 bpm VS 94 ± 18 bpm), mean (84 ± 16 bpm VS 93 ± 18 bpm), and peak HR (94 ± 17 bpm VS 105 ± 19 bpm) were lower (p < 0.05), whereas core temperature was not different between seasons in either condition (p > 0.05). In HOT, ratings of discomfort were higher in summer (15 ± 3) than winter (13 ± 3; p > 0.05), but ratings of thermal sensation and sweat rate were similar between seasons (p > 0.05). The surgical team in burns in Western Australia can obtain some of the physiological adaptations that result from seasonal acclimatization, but not all. That is most likely due to a lower than required amount of outdoor heat exposure in summer, to induce all physiological and perceptual adaptations.
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  • 文章类型: Journal Article
    目的:本研究旨在确定放置在不同身体部位的强制加温毯对择期开腹手术患者核心温度的影响。
    方法:前瞻性,单中心,随机化,控制,单盲试验。
    方法:将537例开腹手术患者随机分为A组,B,和C,并配有不同的强制空气变暖毯。A组给予上半身毯子,B组下半身毯子,和C组一个车底毯子。术中低体温的发生率,体温过低之前保持核心温度超过36℃的时间,体温过低的持续时间,复温率,比较3组并发症发生情况。
    结果:B组51.4%的患者发生术中低体温,A组37.6%的患者,和34.1%的患者在C组(P=0.002)。在A组和C组中,保持核心温度在36℃以上的时间在低温之前更长(log-rankP=.006)。在A组和C组中,体温过低的持续时间较短,复温率较高,寒战和术后恶心呕吐的发生率较低,
    结论:在接受择期开腹手术的患者中,上身部分或下身区域的强制加温毯减少了术中体温过低,延长了体温过低之前维持36℃以上的时间,当核心温度降至36℃以下时,可以更好地防止进一步的低温。此外,在减轻麻醉后监护室的寒战和术后恶心和呕吐方面明显优于对照组.
    OBJECTIVE: This study aimed to determine the effect of a forced-air warming blanket placed on different body parts on the core temperature of patients undergoing elective open abdominal surgery.
    METHODS: Prospective, single-center, randomized, controlled, single-blind trial.
    METHODS: A total of 537 patients who underwent open abdominal surgery were randomized into groups A, B, and C and provided with different forced-air warming blankets. Group A was given an upper body blanket, group B a lower body blanket, and group C an underbody blanket. The incidence of intraoperative hypothermia, the time maintaining the core temperature over 36 ℃ before hypothermia, the duration of hypothermia, the rewarming rate, and relevant complications were compared among three groups.
    RESULTS: Intraoperative hypothermia occurred in 51.4% of patients in group B, 37.6% of patients in group A, and 34.1% of patients in group C (P = .002). Maintaining the core temperature above 36 ℃ was longer before hypothermia in groups A and C (log-rank P = .006). In groups A and C, the duration of hypothermia was shorter, the rewarming rate was higher, and the incidence of shivering and postoperative nausea and vomiting were lower, compared to group B.
    CONCLUSIONS: In patients undergoing elective open abdominal surgery, a forced-air warming blanket on the upper body part or underbody area decreased intraoperative hypothermia, prolonged the time to maintain the core temperature above 36 ℃ before hypothermia, and could better prevent further hypothermia when the core temperature had decreased below 36 ℃. In addition, it was significantly superior in reducing shivering and postoperative nausea and vomiting in the postanesthesia care unit.
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  • 文章类型: Journal Article
    背景:直肠温度(RT)是核心温度的重要指标,对宠物疾病的诊断和治疗具有指导意义。
    目的:开发和评估一种基于机器学习的替代方法,以使用表面温度确定猫和狗的核心温度。
    方法:在2022年3月至2022年5月间治疗了200只猫和200只狗。
    方法:本研究包括一组猫和狗。测量了核心温度和表面体温。使用交叉验证方法训练多种机器学习方法,并在一个回顾性测试集和一个前瞻性测试集中进行评估。
    结果:机器学习模型可以在使用表面温度预测猫和狗的核心温度方面取得有希望的性能。在回顾性测试集中,猫和狗的均方根误差(RMSE)分别为0.25和0.15,以及预期测试集中的0.15和0.14。
    结论:机器学习模型可以使用容易获得的体表温度来准确预测猫和狗的伴侣动物的核心温度。
    BACKGROUND: Rectal temperature (RT) is an important index of core temperature, which has guiding significance for the diagnosis and treatment of pet diseases.
    OBJECTIVE: Development and evaluation of an alternative method based on machine learning to determine the core temperatures of cats and dogs using surface temperatures.
    METHODS: 200 cats and 200 dogs treated between March 2022 and May 2022.
    METHODS: A group of cats and dogs were included in this study. The core temperatures and surface body temperatures were measured. Multiple machine learning methods were trained using a cross-validation approach and evaluated in one retrospective testing set and one prospective testing set.
    RESULTS: The machine learning models could achieve promising performance in predicting the core temperatures of cats and dogs using surface temperatures. The root mean square errors (RMSE) were 0.25 and 0.15 for cats and dogs in the retrospective testing set, and 0.15 and 0.14 in the prospective testing set.
    CONCLUSIONS: The machine learning model could accurately predict core temperatures for companion animals of cats and dogs using easily obtained body surface temperatures.
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  • 文章类型: Journal Article
    众所周知,热疗会极大地损害神经肌肉功能和动态平衡。然而,女性参与者在穿越障碍物时,更高水平的热疗是否可能改变下肢模拟肌肉的激活,目前尚不清楚.因此,我们研究了女性参与者穿越障碍时,口腔温度系统升高对下肢模拟肌肉激活的影响。招募了18名女性参与者,他们进行了对照试验(Con)和两次渐进式被动加热试验,其中使用45°C水浴将口腔温度(Toral)升高了Δ1°C和Δ2°C。在每次审判中,我们评估了穿越障碍物高度10%时的下肢模拟肌肉激活,20%,和30%的参与者的腿长和脚趾,识别并分析了脚趾上障碍物和脚跟撞击事件。在所有事件中,当前肢和后肢都越过20%和30%腿长的障碍物高度时,下肢模拟的肌肉激活在Δ2°C中大于Δ1°C和Con(均p<0.001)。然而,在所有障碍物高度上,Δ1°C和Con之间的下肢模拟肌肉激活没有差异(p>0.05)。这项研究得出的结论是,更高水平的热疗会导致更大的下肢模拟肌肉激活,以确保女性穿越20%腿长或更高的障碍物高度时的安全性和稳定性。
    It is well known that hyperthermia greatly impairs neuromuscular function and dynamic balance. However, whether a greater level of hyperthermia could potentially alter the lower limb simulated muscle activation when crossing an obstacle in female participants remains unknown. Therefore we examined the effect of a systematic increase in oral temperature on lower limb simulated muscle activation when crossing an obstacle in female participants. Eighteen female participants were recruited where they underwent a control trial (Con) and two progressive passive heating trials with Δ 1°C and Δ 2°C increase of oral temperature (Toral) using a 45°C water bath. In each trial, we assessed lower limb simulated muscle activation when crossing an obstacle height of 10%, 20%, and 30% of the participant\'s leg length and toe-off, toe-above-obstacle and heel-strike events were identified and analyzed. In all events, the lower limb simulated muscle activation were greater in Δ2°C than Δ1°C and Con when both leading and trailing limbs crossed the obstacle height of 20% and 30% leg length (all p < 0.001). However, the lower limb simulated muscle activation were not different between Δ1°C and Con across all obstacle heights (p > 0.05). This study concluded that a greater level of hyperthermia resulted in a greater lower limb simulated muscle activation to ensure safety and stability when females cross an obstacle height of 20% leg length or higher.
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  • 文章类型: Journal Article
    核心体温(Tc)是鸟类和哺乳动物体内平衡的关键方面,并且越来越多地用作动物对其环境适应性的生物标志物。周期图和余弦分析可用于根据在具有有限的存储容量和电池寿命的记录器上获得的数据来估计Tc的昼夜节律的特征。可以操纵采样间隔以最大化记录周期,但是采样间隔对周期图或余弦分析输出的影响是未知的。信号分析理论提供了一些基本准则,但这些指南从未在Tc数据上进行过测试。我们在1-,来自9种鸟类或哺乳动物的5-或10-min间隔,并重新采样这些数据,以长达240分钟的间隔模拟测井。首先使用Lomb-Scargle周期图来分析节律的周期,和介子,振幅,使用余弦分析获得原始和重新采样数据的顶相和调整后的决定系数(R2)。大于60分钟的采样间隔不影响平均测量值,振幅,顶期或调整后的R2,但确实影响了对节律周期的估计。在大多数物种中,当使用超过120分钟的间隔时,无法检测到该时间段.在所有单个配置文件中,30分钟的采样间隔将介观和振幅的值修改小于0.1°C,调整后的R2小于0.1。间隔30分钟,除小鼠外,所有物种的顶相都精确到15分钟内。调整后的R2随着采样频率的降低而增加。在大多数情况下,30分钟的采样间隔使用周期图和余弦分析提供了对昼夜节律的可靠估计。我们的发现将帮助生物学家选择采样间隔以符合他们的研究目标。
    Core body temperature (T c) is a critical aspect of homeostasis in birds and mammals and is increasingly used as a biomarker of the fitness of an animal to its environment. Periodogram and cosinor analysis can be used to estimate the characteristics of the circadian rhythm of T c from data obtained on loggers that have limited memory capacity and battery life. The sampling interval can be manipulated to maximise the recording period, but the impact of sampling interval on the output of periodogram or cosinor analysis is unknown. Some basic guidelines are available from signal analysis theory, but those guidelines have never been tested on T c data. We obtained data at 1-, 5- or 10-min intervals from nine avian or mammalian species, and re-sampled those data to simulate logging at up to 240-min intervals. The period of the rhythm was first analysed using the Lomb-Scargle periodogram, and the mesor, amplitude, acrophase and adjusted coefficient of determination (R 2) from the original and the re-sampled data were obtained using cosinor analysis. Sampling intervals longer than 60 min did not affect the average mesor, amplitude, acrophase or adjusted R 2, but did impact the estimation of the period of the rhythm. In most species, the period was not detectable when intervals longer than 120 min were used. In all individual profiles, a 30-min sampling interval modified the values of the mesor and amplitude by less than 0.1°C, and the adjusted R 2 by less than 0.1. At a 30-min interval, the acrophase was accurate to within 15 min for all species except mice. The adjusted R 2 increased as sampling frequency decreased. In most cases, a 30-min sampling interval provides a reliable estimate of the circadian T c rhythm using periodogram and cosinor analysis. Our findings will help biologists to select sampling intervals to fit their research goals.
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  • 文章类型: Journal Article
    目标:极端高温事件的频率不断上升,对与高温有关的疾病和死亡构成了不断升级的威胁,给全球医疗保健系统带来额外压力。与热有关的问题的风险是否与性别有关,尤其是老年人,仍然不确定。
    方法:16名年龄相仿(69±5岁)的男性和15名女性暴露于39.1±0.3°C的空气温度和25.1±1.9%的相对湿度(RH),在20分钟的坐着休息和至少40分钟的低强度(10W)自行车运动。在第30分钟开始,RH每5分钟逐渐增加2%。我们测量了出汗率,心率,热感觉,以及胃肠道温度(Tgi)和皮肤温度(Tsk)的升高。
    结果:Tgi从30分钟到60分钟持续增加,女性和男性之间没有显着差异(0.012±0.004°C/minvs.0.011±0.005°C/min;p=0.64)。同样,Tsk的增加在女性和男性之间没有差异(0.044±0.007°C/min与0.038±0.011°C/min;p=0.07)。女性的出汗率低于男性(0.29±0.06vs.0.45±0.14mg/m2/min;p<0.001),特别是在相对湿度超过30%时。没有观察到心率和热感觉的性别差异。
    结论:当湿度超过30%时,在39°C的环境温度下进行低强度运动时,老年女性的出汗率明显低于男性。然而,老年男性和女性都表现出可比的核心温度上升,皮肤温度,和平均体温,表明与热暴露相关的类似健康风险。
    OBJECTIVE: The rising frequency of extreme heat events poses an escalating threat of heat-related illnesses and fatalities, placing an additional strain on global healthcare systems. Whether the risk of heat-related issues is sex specific, particularly among the elderly, remains uncertain.
    METHODS: 16 men and 15 women of similar age (69 ± 5 years) were exposed to an air temperature of 39.1 ± 0.3 °C and a relative humidity (RH) of 25.1 ± 1.9%, during 20 min of seated rest and at least 40 min of low-intensity (10 W) cycling exercise. RH was gradually increased by 2% every 5 min starting at minute 30. We measured sweat rate, heart rate, thermal sensation, and the rise in gastrointestinal temperature (Tgi) and skin temperature (Tsk).
    RESULTS: Tgi consistently increased from minute 30 to 60, with no significant difference between females and males (0.012 ± 0.004 °C/min vs. 0.011 ± 0.005 °C/min; p = 0.64). Similarly, Tsk increase did not differ between females and males (0.044 ± 0.007 °C/min vs. 0.038 ± 0.011 °C/min; p = 0.07). Females exhibited lower sweat rates than males (0.29 ± 0.06 vs. 0.45 ± 0.14 mg/m2/min; p < 0.001) in particular at relative humidities exceeding 30%. No sex differences in heart rate and thermal sensation were observed.
    CONCLUSIONS: Elderly females exhibit significantly lower sweat rates than their male counterparts during low-intensity exercise at ambient temperatures of 39 °C when humidity exceeds 30%. However, both elderly males and females demonstrate a comparable rise in core temperature, skin temperature, and mean body temperature, indicating similar health-related risks associated with heat exposure.
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  • 文章类型: Journal Article
    背景:辣椒素,辣椒提取物,可以刺激增加的皮肤血流量(SkBF),并在应用领域感知到温暖的感觉。更大的表面积应用可以发挥更系统的体温调节响应。辣椒素可以帮助保持热量传输到远端,减少寒冷天气伤害的风险。然而,在寒冷运动前局部应用辣椒素乳膏的体温调节和知觉影响尚不清楚。
    方法:在上肢和下肢涂抹0.1%辣椒素或对照乳膏(共10g,〜40-50%的身体表面积),11名穿着短裤和T恤的参与者暴露于30分钟的寒冷中(0°C,40%相对湿度)。暴露包括5分钟坐着休息,步行20分钟(1.6m·s-1,5%坡度),和5分钟坐着休息。温度(皮肤,core),SkBF,皮肤导电性,心率,热感觉,并在整个过程中测量热舒适度。
    结果:辣椒素治疗与对照治疗的皮肤温度没有差异(治疗平均值:30.0±2.5,30.1±2.4°C,分别,p=0.655),核心温度(处理平均值:37.3±0.5,37.4±0.4°C,分别,p=0.113),SkBF(治疗平均值:-8.4±10.0,-11.1±10.7A.U.,分别,p=0.492),皮肤电导率(治疗平均值:-0.7±5.1,0.4±6.4µS,分别,p=0.651),或心率(治疗平均值:83±29,85±28次·分钟-1,p=0.234)。辣椒素和对照治疗在热感觉(p=0.521)和热舒适(p=0.982)方面也没有差异,感知结果与感觉“酷”和“只是不舒服”相对应,\"分别。
    结论:在寒冷环境中行走前,对暴露的四肢局部应用0.1%辣椒素不会改变全身的体温调节或热感知。
    Capsaicin, a chili pepper extract, can stimulate increased skin blood flow (SkBF) with a perceived warming sensation on application areas. Larger surface area application may exert a more systemic thermoregulatory response. Capsaicin could assist with maintaining heat transport to the distal extremities, minimizing cold weather injury risk. However, the thermoregulatory and perceptual impact of topical capsaicin cream application prior to exercise in the cold is unknown.
    Following application of either a 0.1% capsaicin or control cream to the upper and lower extremities (10 g total, ∼40-50% body surface area), 11 participants in shorts and a t-shirt were exposed to 30 min of cold (0 °C, 40% relative humidity). Exposures comprised of 5 min seated rest, 20 min walking (1.6 m·s-1, 5% grade), and 5 min seated rest. Temperature (skin, core), SkBF, skin conductivity, heart rate, thermal sensation, and thermal comfort were measured throughout.
    The capsaicin treatment did not differ from the control treatment in skin temperature (treatment mean: 30.0 ± 2.5, 30.1 ± 2.4 °C, respectively, p = 0.655), core temperature (treatment mean: 37.3 ± 0.5, 37.4 ± 0.4 °C, respectively, p = 0.113), SkBF (treatment mean: -8.4 ± 10.0, -11.1 ± 10.7 A.U., respectively, p = 0.492), skin conductivity (treatment mean: -0.7 ± 5.1, 0.4 ± 6.4 µS, respectively, p = 0.651), or heart rate (treatment mean: 83 ± 29, 85 ± 28 beats·minute-1, respectively, p = 0.234). The capsaicin and control treatments also did not differ in thermal sensation (p = 0.521) and thermal comfort (p = 0.982), with perceptual outcomes corresponding with feeling \"cool\" and \"just uncomfortable,\" respectively.
    0.1% topical capsaicin application to exposed limbs prior to walking in a cold environment does not alter whole-body thermoregulation or thermal perception.
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