背景:睡眠质量差会导致早晨血压升高(MBPS),心血管疾病(CVD)事件的独立危险因素。闹钟等外部因素引起的觉醒,也可能有助于增加MBPS。
目的:目的:(1)比较自然觉醒和强迫觉醒之间的MBPS和睡眠质量参数,(2)检查强迫觉醒对MBPS的潜在影响,独立于睡眠质量。
方法:32名健康成年人参与了这项初步研究,其中包括一个晚上的自然觉醒和一个晚上的强迫觉醒(即,五个小时后,睡眠被闹钟打断)。使用多感官腕带和睡眠日记测量客观和自我报告的睡眠质量参数,分别,并且使用连续血压监测仪评估逐搏血压变异性.分析包括配对t检验(目标1)和线性混合模型(目标2)。
结果:参与者主要由年轻人组成,健康,和受过高等教育的亚洲成年人。在强醒的睡眠之夜,MBPS显著提高,睡眠发作后客观觉醒较低,观察到自我报告的睡眠潜伏期较低,与自然觉醒的夜晚相比。在控制年龄后,强迫觉醒与MBPS增加显著相关,性别,平均动脉压,和睡眠质量。
结论:强迫觉醒可能会显著增加MBPS,因此增加CVD事件的风险.研究结果应在更大的样本中进行验证。还需要进一步的研究来检查强制觉醒对心血管疾病患者MBPS的影响。
BACKGROUND: Poor sleep quality can cause an increase in morning blood pressure surge (MBPS), an independent risk factor of cardiovascular disease (CVD) events. Awakening induced by external factors such as alarm clocks, may also contribute to increased MBPS.
OBJECTIVE: To (1) compare the MBPS and sleep quality parameters between natural and forced awakenings and (2) examine the potential impact of forced awakening on MBPS, independent of sleep quality.
METHODS: Thirty-two healthy adults participated in this pilot study, which included one night of natural awakening and one night of forced awakening (i.e., sleep was interrupted by an alarm after five hours). Objective and self-reported sleep quality parameters were measured using a multisensory wristband and sleep diaries, respectively, and beat-to-beat blood pressure variability was assessed using a continuous blood pressure monitor. Analyses included a paired t-test (objective 1) and linear mixed models (objective 2).
RESULTS: Participants predominantly consisted of young, healthy, and highly educated Asian adults. During the night of sleep with forced awakening, significantly higher MBPS, lower objective wakefulness after sleep onset, and lower self-reported sleep latency were observed, compared to the night with natural awakening. Forced awakening was significantly associated with increased MBPS after controlling for age, sex, mean arterial pressure, and sleep quality.
CONCLUSIONS: Forced awakening may significantly increase MBPS, consequently heightening the risk of CVD events. Study findings should be validated in a larger sample. Further research is also warranted to examine the impact of forced awakening on MBPS in individuals with CVD.