Binge eating disorder

暴食症
  • 文章类型: Journal Article
    本文旨在回顾针对患有神经性贪食症(BN)和暴饮暴食症(BED)的成年人和年轻人的基于证据的心理治疗和精神药理学治疗。成人和儿童和青少年的治疗分开讨论,包括在青少年中管理这些疾病的发展考虑。尽管已经为患有BN或BED的成年人建立了几种基于证据的心理治疗和精神药理学治疗方案,在儿童和青少年中,对这些饮食失调的管理的经验支持要少得多。这篇综述最后讨论了有希望的模式和创新,强调将技术整合到治疗方法中的潜在效用。尽管几十年的治疗发展和测试,相当比例的BN或BED患者对目前的循证治疗没有反应,强调需要在这些领域继续研究。未来的研究应该集中在测试不同样本中的心理治疗方法,随机对照试验,以及可以在社区环境中轻松扩展和实施的治疗方法。
    This article aims to review the current evidence-based psychotherapy and psychopharmacological treatments for adults and youths with bulimia nervosa (BN) and binge-eating disorder (BED). Treatments for adults and for children and adolescents are discussed separately, including developmental considerations in the management of these disorders among youths. Although several evidence-based psychotherapy and psychopharmacological treatment options have been established for adults with BN or BED, there is much less empirical support for the management of these eating disorders among children and adolescents. This review concludes by discussing promising modalities and innovations, highlighting the potential utility of integrating technology into treatment approaches. Despite decades of treatment development and testing, a sizable proportion of individuals with BN or BED do not respond to the current evidence-based treatments, highlighting the need for continued research in these domains. Future research should focus on testing psychotherapy treatments among diverse samples in large, randomized controlled trials, as well as on treatments that can be easily scaled and implemented in community settings.
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  • 文章类型: Journal Article
    进食障碍(ED)是以危险的进食行为为特征的心理障碍,包括长期禁食和暴饮暴食。精神障碍合并症(例如,焦虑和抑郁),以及睡眠困难,是常见的,可能会干扰治疗反应。这项工作调查了睡眠质量,昼夜节律偏好,与健康对照(HC)相比,ED患者的睡眠障碍以及ED治疗对患者睡眠的影响。在Pubmed上进行文献检索,WebofScience,Medline,PsychInfo包括27项研究。进行了随机效应分析(样本进食障碍=711;样本健康对照=653),并根据ED亚组计算亚组分析:神经性厌食症,神经性贪食症,暴饮暴食症。全样本分析显示患者的生理和主观睡眠质量较差。亚组分析表明,仅在神经性厌食症中存在较差的生理睡眠。两项报告昼夜节律偏好和睡眠障碍的研究显示,患者的晚上偏好更高,患者和健康对照组之间的呼吸暂停患病率没有差异。分别。一些研究表明,专门的饮食失调治疗(例如,ED的认知行为疗法)可以改善患者的睡眠质量。尽管这些发现强调了ED患者与健康对照组相比睡眠较差,饮食失调中睡眠改变的潜在机制仍有待确定。
    Eating disorders (ED) are psychological disorders characterized by dangerous eating behaviours, including protracted fasting and binge eating. Mental disorders comorbidities (e.g., anxiety and depression), as well as sleep difficulties, are common and might interfere with treatment response. This work investigated sleep quality, circadian preferences, and sleep disorders in ED patients compared to healthy controls (HC) and the impact of ED treatment on patients\' sleep. A literature search on Pubmed, Web of Science, Medline, and PsychInfo included 27 studies. Random effect analyses were performed (sample eating disorders = 711; sample healthy controls = 653) and subgroup analyses were calculated based on the ED subgroups: Anorexia Nervosa, Bulimia Nervosa, Binge Eating Disorder. Whole sample analyses showed poorer physiological and subjective sleep quality in patients. Subgroup analyses showed that poorer physiological sleep was present only in anorexia nervosa. Two studies reporting circadian preferences and sleep disorders showed higher evening preference in patients and no differences in apnea prevalence between patients and healthy controls, respectively. Some studies suggested that specialized eating disorder treatments (e.g., Cognitive Behavioural Therapy for ED) can improve sleep quality in patients. Although these findings highlight poorer sleep in patients with ED compared to healthy controls, the mechanisms underlying sleep alterations in eating disorders remain to be identified.
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  • 文章类型: Journal Article
    目的:进食障碍(ED)意识低。我们评估了ED症状识别,感知到需要治疗,感知到的痛苦,感知的可接受性,感知的患病率因ED患者的性别而异。
    方法:276名社区参与者被随机分配到三种性别条件之一(女性,男性,和非二进制),阅读三个小插图,描述三个患有ED症状的不同个体[神经性厌食症(AN),神经性贪食症(BN),和暴饮暴食症(BED)],然后回答了一系列与参与者ED症状识别相关的问题,感知到需要治疗,感知到与ED症状相关的痛苦,感知的可接受性(例如,有ED可能不会太坏的程度),和感知的患病率。进行混合方差分析和卡方分析以检查组间的差异。
    结果:性别状况在结局变量中没有显著的主要影响。ED类型对问题识别有主要影响,感知到需要治疗,感知到的痛苦水平,和感知的患病率,参与者更有可能认识到AN和BN小插曲中的问题,而不是BED小插曲,参考治疗,并在小插图中评价比BN和BED小插图更高的痛苦感知水平,并且认为BN小插图的患病率高于AN小插图。感知患病率存在显著的性别与条件的交互作用,参与者对女性和非二元个体的AN患病率高于男性,女性的BN患病率高于非二元个体和男性。
    结论:这些结果强调了对ED进行教育的重要性以及对ED可以发生在任何个体中的认识,不管他们的性别认同。
    方法:一级,随机化的实验研究。
    OBJECTIVE: Eating disorder (ED) awareness is low. We assessed if ED symptom recognition, perceived need for treatment, perceived distress, perceived acceptability, and perceived prevalence differed depending on the gender of the individual with the ED.
    METHODS: 276 community participants were randomly assigned to one of three gender conditions (female, male, and non-binary), read three vignettes describing three different individuals with ED symptoms [anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED)], and then answered a series of questions related to participants ED symptom recognition, perceived need for treatment, perceived distress associated with having ED symptoms, perceived acceptability (e.g., the extent to which it may not be too bad to have an ED), and perceived prevalence. Mixed ANOVAs and chi-square analyses were conducted to examine differences between groups.
    RESULTS: There were no significant main effects of gender condition across the outcome variables. There were main effects of ED type for problem recognition, perceived need for treatment, perceived level of distress, and perceived prevalence, with participants being more likely to recognize a problem in the AN and BN vignettes than the BED vignettes, refer for treatment and rate a higher perceived level of distress in then AN vignette than the BN and BED vignettes, and perceive a higher prevalence rate in the BN vignette than the AN vignette. There was a significant gender by condition interaction for perceived prevalence, with participants rating a higher prevalence of AN in women and non-binary individuals than men and a higher prevalence of BN in women than non-binary individuals and men.
    CONCLUSIONS: These results highlight the importance of education on EDs and awareness that EDs can occur in any individual, regardless of their gender identification.
    METHODS: Level I, experimental study with randomization.
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  • 文章类型: Journal Article
    由于很少有前瞻性研究确定了预测未来发生阈值/阈值下神经性厌食症(AN)的风险因素,神经性贪食症(BN),暴饮暴食症(BED),和清除障碍(PD),我们分析了在为期8年的青少年女孩队列中收集的前瞻性数据,以提高对风险因素特异性的认识.从德克萨斯州的中学招募的青春期女孩(N=492;M年龄=13.02[SD=0.73],年龄范围=11-15)填写了评估基线危险因素的问卷,并在8年内每年进行一次评估饮食失调的诊断性访谈。只有低BMI预测未来的AN发作。压力要薄,薄理想内化,身体不满,负面情绪,低父母支持,饮食病理学建模预测了未来的BN发作。压力要薄,薄理想内化,负面情绪,低父母支持,饮食病理学建模预测了未来的BED发作。压力要薄,身体不满,饮食限制,低父母支持,饮食病理学建模,高BMI预测未来的PD发病。预测效应是中等到大的。结果支持饮食失调的病因学理论,这些理论假定了对理想的追求,身体不满,负面影响,饮食限制,人际关系问题会增加大多数饮食失调的风险。有证据表明体重较低的女孩有患AN的风险,而体重高的女孩有患PD的风险是新奇的。尽管有几个风险因素预测了BN的未来发作,床,还有PD,结果表明,AN的危险因素在质量上是不同的,需要进一步研究.
    Because very few prospective studies have identified risk factors that predicted future onset of threshold/subthreshold anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), and purging disorder (PD), we analyzed prospective data collected from a large cohort of adolescent girls followed over an 8-year period to advance knowledge about risk factor specificity. Adolescent girls recruited from middle schools in Texas (N = 492; M age = 13.02 [SD = 0.73], age range = 11-15) completed questionnaires assessing risk factors at baseline and diagnostic interviews assessing eating disorders annually over 8 years. Only low BMI predicted future AN onset. Pressure to be thin, thin-ideal internalization, body dissatisfaction, negative emotionality, low parent support, and modeling of eating pathology predicted future BN onset. Pressure to be thin, thin-ideal internalization, negative emotionality, low parent support, and modeling of eating pathology predicted future BED onset. Pressure to be thin, body dissatisfaction, dietary restraint, low parent support, modeling of eating pathology, and high BMI predicted future PD onset. Predictive effects were medium-to-large. Results support etiological theories of eating disorders that postulate the pursuit of the thin ideal, body dissatisfaction, negative affect, dietary restraint, and interpersonal issues increase risk for most eating disorders. The evidence that girls with low body weight are at risk for AN, whereas girls with high body weight are at risk for PD are novel. Although several risk factors predicted future onset of BN, BED, and PD, results suggest that risk factors for AN are qualitatively distinct and should be investigated further.
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  • 文章类型: Journal Article
    超加工食品(UPFs),如糕点,包装零食,快餐,加糖饮料在现代食品供应中占主导地位,并与许多公共卫生问题密切相关。虽然UPF摄入量对身体健康的影响已得到充分证明(例如,心脏代谢疾病的风险增加),较少的实证讨论强调了长期UPF消费的心理健康后果。值得注意的是,UPFs的独特特征(例如,人工高水平的增强成分)影响生物过程(例如,多巴胺信号)的方式可能会导致某些个体的心理功能较差。重要的是,黄金标准的行为生活方式干预和专门针对饮食失调的治疗方法不承认UPFs可能在敏感奖励相关的神经功能中发挥的直接作用,扰乱代谢反应,并激发随后的UPF渴望和摄入。缺乏对UPFs对心理健康的影响的考虑尤其成问题,因为对这些食物的成瘾性的科学支持越来越多,并且超加工食物成瘾(UPFA)作为一种新的临床表型得到了14-20%的认可。本综述的总体目标是总结UPFs如何影响心理健康的科学,强调贡献的生物学机制。具体来说,作者将(1)描述公司赞助的研究和财务议程如何促进关于UPFs在健康中的作用的争论和辩论;(2)定义UPFs及其营养特征;(3)审查观察到的UPF摄入量与心理健康状况之间的关联,尤其是抑郁症患者;(4)概述UPFA的证据;(5)描述UPFA和饮食失调合并症的细微差别治疗注意事项。
    Ultra-processed foods (UPFs) like pastries, packaged snacks, fast foods, and sweetened beverages have become dominant in the modern food supply and are strongly associated with numerous public health concerns. While the physical health consequences of UPF intake have been well documented (e.g., increased risks of cardiometabolic conditions), less empirical discussion has emphasized the mental health consequences of chronic UPF consumption. Notably, the unique characteristics of UPFs (e.g., artificially high levels of reinforcing ingredients) influence biological processes (e.g., dopamine signaling) in a manner that may contribute to poorer psychological functioning for some individuals. Importantly, gold-standard behavioral lifestyle interventions and treatments specifically for disordered eating do not acknowledge the direct role that UPFs may play in sensitizing reward-related neural functioning, disrupting metabolic responses, and motivating subsequent UPF cravings and intake. The lack of consideration for the influences of UPFs on mental health is particularly problematic given the growing scientific support for the addictive properties of these foods and the utility of ultra-processed food addiction (UPFA) as a novel clinical phenotype endorsed by 14-20% of individuals across international samples. The overarching aim of the present review is to summarize the science of how UPFs may affect mental health, emphasizing contributing biological mechanisms. Specifically, the authors will (1) describe how corporate-sponsored research and financial agendas have contributed to contention and debate about the role of UPFs in health; (2) define UPFs and their nutritional characteristics; (3) review observed associations between UPF intake and mental health conditions, especially with depression; (4) outline the evidence for UPFA; and (5) describe nuanced treatment considerations for comorbid UPFA and eating disorders.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:暴食症(BED)是一种常见且致残的疾病,通常表现为多种精神病和肥胖相关的合并症。循证治疗要么是资源密集型(心理治疗),要么有副作用(药物):这些治疗在大约50%的病例中获得缓解。需要新的治疗方法。
    目的:这项随机假对照试验旨在评估可行性,在家的可接受性和初步功效,在暴饮暴食症的成年人中,自我管理的经颅直流电刺激(tDCS)和注意力偏见修正训练(ABMT)。
    方法:82名暴食症患者被随机分配到使用ABMT的真实tDCS,假tDCS与ABMT,仅ABMT或waitlist控件。干预组在2-3周内接受了十次分配的治疗。tDCS(2mA,20分钟)使用针对背外侧前额叶皮层的双侧(阳极右/阴极左)蒙太奇进行自我管理。结果在基线评估,治疗后和6周随访。
    结果:超过了预定的可行性标准(招募≥80名参与者和保留率≥75%),治疗完成率高(98.7%)。所有干预措施都减少了暴饮暴食事件,基线和随访之间的进食障碍症状和相关的精神病理学,相对于waitlist对照(变化分数的中等到大的组间效应大小)。与比较器相比,变化分数的中小效应大小有利于ABMT的实际tDCS,表明verum干预产生了更好的结果。
    结论:在家里,使用ABMT自我管理的tDCS是可行和可接受的,和疗效的初步数据是有希望的。这种方法可能是对暴食症的既定治疗方法的有用且可扩展的替代或辅助方法。验证性试验可以,并且应该,被追求。
    BACKGROUND: Binge eating disorder (BED) is a common and disabling condition, typically presenting with multiple psychiatric and obesity-related comorbidities. Evidence-based treatments are either resource-intensive (psychotherapies) or have side-effects (medications): these achieve remission in around 50% of cases. Novel treatments are needed.
    OBJECTIVE: This randomised sham-controlled trial aimed to assess feasibility, acceptability and preliminary efficacy of at-home, self-administered transcranial direct current stimulation (tDCS) and attention bias modification training (ABMT) in adults with binge eating disorder.
    METHODS: Eighty-two participants with binge eating disorder were randomly allocated to real tDCS with ABMT, sham tDCS with ABMT, ABMT only or waitlist control. Intervention groups received ten sessions of their allocated treatment over 2-3 weeks. tDCS (2 mA, 20 min) was self-administered using a bilateral (anode right/cathode left) montage targeting the dorsolateral prefrontal cortex. Outcomes were assessed at baseline, post-treatment and 6-week follow-up.
    RESULTS: Prespecified feasibility criteria (recruitment ≥80 participants and retention rate ≥75%) were exceeded, and treatment completion rates were high (98.7%). All interventions reduced binge eating episodes, eating disorder symptoms and related psychopathology between baseline and follow-up, relative to waitlist control (medium-to-large between-group effect sizes for change scores). Small-to-medium effect sizes for change scores favoured real tDCS with ABMT versus comparators, suggesting the verum intervention produces superior outcomes.
    CONCLUSIONS: At-home, self-administered tDCS with ABMT is feasible and acceptable, and preliminary data on efficacy are promising. This approach could be a useful and scalable alternative or adjunct to established treatments for binge eating disorder. Confirmatory trials can, and should, be pursued.
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  • 文章类型: Journal Article
    目标进食障碍(ED)是全球新兴的公共卫生问题,尤其是在本科阶段学习的年轻人。这项研究旨在评估饮食失调的频率,他们的类型,这些学生的饮食行为紊乱。此外,它旨在确定诸如体重问题之类的因素,形状关注,饮食关注,和克制,使用标准化的饮食失调检查问卷(EDE-Q)评估BMI对饮食失调影响的变化趋势。方法在这项横断面研究中,从2022年7月至2023年11月,来自四所公立大学的400名本科生(18-25岁)参加了会议。使用饮食失调检查问卷(EDE-Q)收集数据。使用SPSS版本27计算进食障碍的频率。结果在参与者中,21.75%(n=84)被鉴定为具有超过临床界限的分数。该组包括5.5%的男性(n=22)和16%的女性(n=64)。在形状关注子量表中观察到四个子量表中的患病率最高(10.5%)。客观暴饮暴食(19.3%)是最明显的饮食失调态度。非典型神经性厌食症占不同饮食失调的13.8%,而在19.5%(n=78)的个体中发现饮食紊乱。讨论这项研究提供了对巴基斯坦本科生饮食失调的重要见解,利用EDE-Q6.0。饮食行为紊乱,特别是形状关注和客观暴饮暴食,与这些疾病表现出显著的相关性。体重不满是一个突出的预测因素,暗示社会影响。该研究还揭示了BMI和饮食失调之间的中等相关性,挑战传统的假设。此外,在男性人群中观察到饮食失调患病率的变化趋势。
    Objectives Eating disorders (ED) are an emerging public health issue globally, especially in young adults studying at the undergraduate level. This study aims to assess the frequency of eating disorders, their types, and disordered eating behaviors among such students. Moreover, it aims to identify factors like weight concern, shape concern, eating concern, and restraint, along with assessing the shifting trend of BMI impact on eating disorders using a standardized Eating Disorder Examination Questionnaire (EDE-Q). Methods In this cross-sectional study, 400 undergraduate students (aged 18-25) from four public universities participated from July 2022 to November 2023. Data was collected using the Eating Disorder Examination Questionnaire (EDE-Q). The frequency of eating disorders was computed using SPSS version 27. Results Among the participants, 21.75% (n=84) were identified as having a score surpassing the clinical cut-off. This group comprised 5.5% males (n=22) and 16% females (n=64). The highest prevalence among the four subscales was observed in the Shape Concern subscale (10.5%). Objective binge episodes (19.3%) emerged as the most notable disordered eating attitude. Atypical anorexia nervosa accounted for 13.8% of different eating disorders, while disordered eating was noted in 19.5% (n=78) of individuals. Discussion This study offers critical insights into eating disorders among Pakistan undergraduate students, utilizing the EDE-Q 6.0. Disordered eating behaviors, particularly shape concern and objective binge eating, exhibit significant correlations with these disorders. Weight dissatisfaction emerges as a prominent predictor, suggesting societal influence. The study also reveals a moderate correlation between BMI and eating disorders, challenging conventional assumptions. Furthermore, a changing trend in the prevalence of eating disorders is observed among the male population.
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  • 文章类型: Journal Article
    背景:暴食症(BED)是导致肥胖发展的最常见的饮食失调,因此对患者的生活和健康构成了重大负担。它的特点是复杂的神经生物学,其中包括大脑活动和神经递质分泌的变化。现有的治疗方法是适度有效的,因此,寻找有效和安全的新疗法正在进行中。
    目的:这篇综述研究了经颅直流电刺激(tDCS)在暴食症治疗中的应用。在PubMed/Medline上进行了搜索,研究门,和Cochrane数据库。
    结果:有6项研究与综述主题相匹配。所有患者均使用右侧背外侧前额叶皮质(DLPFC)的阳极刺激。tDCS在减少食物渴望方面被证明是有效的,暴饮暴食的欲望,剧集的数量,和食物摄入。它还改善了抑制控制的结果和进食障碍精神病理学的治疗。解释了tDCS在BED中的潜在作用机制,概述了当前研究的局限性,并对未来的研究提出了建议。
    结论:初步证据表明,将tDCS阳极应用于右侧DLPFC可减少BED的症状。然而,在这种情况下,由于进行的研究数量少,包括的患者数量少,因此在更广泛地使用tDCS时应谨慎。未来的研究应结合神经影像学和神经生理学测量,以阐明tDCS在BED中的潜在作用机制。
    BACKGROUND: Binge eating disorder (BED) is the most common eating disorder among those contributing to the development of obesity, and thus acts as a significant burden on the lives and health of patients. It is characterized by complex neurobiology, which includes changes in brain activity and neurotransmitter secretion. Existing treatments are moderately effective, and so the search for new therapies that are effective and safe is ongoing.
    OBJECTIVE: This review examines the use of transcranial direct current stimulation (tDCS) in the treatment of binge eating disorder. Searches were conducted on the PubMed/Medline, Research Gate, and Cochrane databases.
    RESULTS: Six studies were found that matched the review topic. All of them used the anodal stimulation of the right dorsolateral prefrontal cortex (DLPFC) in BED patients. tDCS proved effective in reducing food cravings, the desire to binge eat, the number of binging episodes, and food intake. It also improved the outcomes of inhibitory control and the treatment of eating disorder psychopathology. The potential mechanisms of action of tDCS in BED are explained, limitations in current research are outlined, and recommendations for future research are provided.
    CONCLUSIONS: Preliminary evidence suggests that the anodal application of tDCS to the right DLPFC reduces the symptoms of BED. However, caution should be exercised in the broader use of tDCS in this context due to the small number of studies performed and the small number of patients included. Future studies should incorporate neuroimaging and neurophysiological measurements to elucidate the potential mechanisms of action of tDCS in BED.
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  • 文章类型: Journal Article
    背景:进食障碍(ED)是由多因素引起的精神健康疾病。目前,目前尚无对西班牙研究其患病率的索引出版物的评论.
    方法:通过系统搜索(MEDLINE,EMBASE和PsycINFO)直到2022年1月。选择了以西班牙语/英语发表的论文,分析了西班牙(人口<65岁)的ED患病率。
    结果:共鉴定出766篇文章(186篇重复删除)。共分析了580篇文章的标题和摘要,共选取67篇文章进行全文分析。共有37项研究分析了西班牙的ED患病率。
    结论:这是第一个分析西班牙ED患病率的范围审查。青春期和青春期是研究最广泛的阶段。ED筛查工具的使用存在高度异质性,诊断工具信息匮乏。
    BACKGROUND: Eating disorders (EDs) are mental health illnesses with a multifactorial origin. At present, no review of indexed publications studying their prevalence in Spain is available.
    METHODS: A scoping review (PROSPERO -CRD42019140884-) was carried out through systematic searches (MEDLINE, EMBASE and PsycINFO) until January 2022. Papers published in Spanish/English analysing the prevalence of EDs in Spain (population < 65 years) were selected.
    RESULTS: A total of 766 articles were identified (186 eliminated as duplicates). A total of 580 articles were analysed on the basis of title and abstract, and 67 articles were selected for full-text analysis. A total of 37 studies analysed the prevalence of EDs in Spain.
    CONCLUSIONS: This is the first scoping review to analyse the prevalence of EDs in Spain. Puberty and adolescence are the most extensively studied stages. There is a high heterogeneity in the use of ED screening tools and a paucity of information on diagnostic tools.
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