Abdominal Surgery

腹部手术
  • 文章类型: Journal Article
    疝修补术是最常见的腹部外科手术之一。腹股沟疝的“金标准”治疗仍然是Lichtenstein网状疝修补术。尽管如此,临床实践继续努力解决有关并发症的问题,如复发,慢性术后疼痛,和感染。各种手术类型导致关于腹股沟管整形手术方法的优缺点的观点相互矛盾。本文介绍了有关非网状腹股沟疝手术治疗的最新数据,描绘最普遍的技术,同时探索它们各自的优点和缺点。此外,对研究人员的经验进行了详细分析。
    Hernioplasty stands as one of the most common abdominal surgical interventions. The \"gold standard\" treatment for inguinal hernias remains Lichtenstein mesh hernioplasty. Nonetheless, clinical practice continues to grapple with issues concerning complications such as recurrence, chronic postoperative pain, and infection. The myriad types of surgery lead to conflicting opinions regarding the superiority and drawbacks of inguinal canal plastic surgery methods. This article presents current data on the surgical treatment of non-mesh inguinal hernias, delineating the most prevalent techniques while exploring their respective advantages and disadvantages. Additionally, the researchers\' experiences are analyzed in detail.
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  • 文章类型: Journal Article
    目的:重复摘除术(DE)已被描述为一种替代肠切除和原发性吻合(IRA)肠重复的方法,但是没有比较研究。这项研究的目的是比较两种手术方法对肠重复的治疗。
    方法:进行了回顾性研究,包括所有接受肠重复治疗的儿童(2005-2023年)。将接受DE的患者与接受IRA的患者进行比较。使用p<0.05确定统计学显著性。获得了伦理上的认可。
    结果:共有51例患者(中位年龄:5个月)接受肠重复治疗,包括27例(53%)接受DE和24例IRA(47%)的患者。产前检测到19例DE患者(70%)和11例IRA患者(46%)的囊性图像(p=0.09)。7例患者(14%)使用腹腔镜进行了摘除术。接受DE的患者第一次进食的时间较短(1比3天,p=0.0001)和住院时间(4天vs6天,p<0.0004)与IRA相比。在68%的肠切除标本中发现了肌肉层。
    结论:与肠切除吻合相比,重复摘除与减少术后住院时间和延迟首次进食相关,且不会增加术后并发症.关于组织学分析,在大多数情况下,眼球摘除似乎是可行的。
    OBJECTIVE: Duplication enucleation (DE) has been described as an alternative to intestinal resection with primary anastomosis (IRA) for intestinal duplications, but no comparative study exists. The aim of this study was to compare both surgical procedures for intestinal duplication.
    METHODS: A retrospective study was performed, including all children treated for intestinal duplication (2005-2023). Patients that underwent DE were compared to those that underwent IRA. Statistical significance was determined using p < 0.05. Ethical approval was obtained.
    RESULTS: A total of 51 patients (median age: 5 months) were treated for intestinal duplication, including 27 patients (53%) that underwent DE and 24 IRA (47%). A cystic image was detected prenatally in 19 patients (70%) with DE and 11 patients (46%) with IRA (p = 0.09). Enucleation was performed using laparoscopy in 7 patients (14%). Patients that underwent DE had shorter time to first feed (1 vs 3 days, p = 0.0001) and length of stay (4 vs 6 days, p < 0.0004) compared to IRA. A muscular layer was identified in 68% of intestinal resection specimens.
    CONCLUSIONS: Compared to intestinal resection with anastomosis, duplication enucleation is associated with decreased postoperative length of stay and delay to first feeds without increasing post-operative complications. Regarding histological analysis, enucleation seems feasible in most cases.
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  • 文章类型: Journal Article
    背景:随着人口老龄化,越来越多的老年人前来做手术。与年龄相关的生理储备和功能能力下降会导致手术后的虚弱和不良结局。因此,优化老年患者的围手术期护理势在必行。增强术后恢复(ERAS)途径和微创手术(MIS)可能会影响手术结果,但目前对老年患者的使用和影响尚不清楚.这项研究的目的是为接受大型腹部手术的老年人的围手术期护理提供循证建议。
    方法:专家共识确定了与围手术期护理相关的关键术语和指标的工作定义。使用PubMed进行了系统的文献综述和荟萃分析,Embase,科克伦图书馆,以及Clinicaltrials.gov数据库,提供24个预先定义的康复主题领域的关键问题,MIS,和ERAS在腹部大手术中(结直肠,上消化道(UGI),疝,和肝胰胆管(HPB))以根据GRADE方法生成循证建议。
    结果:老年人被定义为65岁及以上。最初从搜索参数中检索了超过20,000篇文章。在172项研究的三个主题领域进行了证据综合,对MIS和ERAS主题进行荟萃分析。建议老年患者使用MIS和ERAS,尤其是在接受结直肠手术时。专家意见建议进行康复治疗,停止吸烟和饮酒,纠正所有结直肠贫血,UGI,疝,和老年人的HPB程序。所有建议都是有条件的,证据的确定性低至非常低,结直肠手术中的ERAS项目除外。
    结论:MIS和ERAS适用于接受腹部大手术的老年人,有证据支持在结直肠手术中使用。尽管专家意见支持康复,没有足够的证据支持使用。这项工作已经确定了进一步研究的证据空白,以优化接受大型腹部手术的老年人。
    BACKGROUND: As the population ages, more older adults are presenting for surgery. Age-related declines in physiological reserve and functional capacity can result in frailty and poor outcomes after surgery. Hence, optimizing perioperative care in older patients is imperative. Enhanced Recovery After Surgery (ERAS) pathways and Minimally Invasive Surgery (MIS) may influence surgical outcomes, but current use and impact on older adults patients is unknown. The aim of this study was to provide evidence-based recommendations on perioperative care of older adults undergoing major abdominal surgery.
    METHODS: Expert consensus determined working definitions for key terms and metrics related to perioperative care. A systematic literature review and meta-analysis was performed using the PubMed, Embase, Cochrane Library, and Clinicaltrials.gov databases for 24 pre-defined key questions in the topic areas of prehabilitation, MIS, and ERAS in major abdominal surgery (colorectal, upper gastrointestinal (UGI), Hernia, and hepatopancreatic biliary (HPB)) to generate evidence-based recommendations following the GRADE methodology.
    RESULTS: Older adults were defined as 65 years and older. Over 20,000 articles were initially retrieved from search parameters. Evidence synthesis was performed across the three topic areas from 172 studies, with meta-analyses conducted for MIS and ERAS topics. The use of MIS and ERAS was recommended for older adult patients particularly when undergoing colorectal surgery. Expert opinion recommended prehabilitation, cessation of smoking and alcohol, and correction of anemia in all colorectal, UGI, Hernia, and HPB procedures in older adults. All recommendations were conditional, with low to very low certainty of evidence, with the exception of ERAS program in colorectal surgery.
    CONCLUSIONS: MIS and ERAS are recommended in older adults undergoing major abdominal surgery, with evidence supporting use in colorectal surgery. Though expert opinion supported prehabilitation, there is insufficient evidence supporting use. This work has identified evidence gaps for further studies to optimize older adults undergoing major abdominal surgery.
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    背景:接受大型腹部肿瘤手术的患者容易发生术后并发症,让早期识别变得至关重要。临床恶化之前往往是生命体征的变化,通常由护士每天测量三次。然而,间歇性测量可能会延迟识别临床恶化。持续的生命参数监测可以导致并发症的早期识别和管理,并减少护理工作量。
    目的:比较病房护士和无线连续监测系统(Sensium®无线贴片)之间的生命参数测量值,并评估该贴片是否可以在术后第一周早期检测到有并发症患者的临床恶化。
    方法:重要参数(心率,呼吸频率,和温度)是在接受肝脏肿瘤切除术的患者中收集的,结直肠,或胰腺。将Sensium®贴片测量值与护士测量值进行比较,以评估不一致测量值的百分比。在术后第一周出现并发症的患者中,在临床恶化的情况下(呼吸频率≥15/min,心率≥100/min,温度≥38°C)。
    结果:在227例患者中,22%的患者经历了并发症。Nurse和Sensium®测量在586/2272测量中存在差异(26%)。在506/586差异(86%)中,这是由于呼吸频率(差异≥4/min).与护士相比,Sensium®贴片在术后第一周的并发症中检测到呼吸频率提前14小时升高和心率提前2小时升高。对于温度,没有观察到差异。
    结论:使用Sensium®无线贴片的连续监测有望在接受大型肿瘤腹部手术的患者中早期识别并发症。
    BACKGROUND: Patients undergoing major oncological abdominal surgery are prone to postoperative complications, making early recognition crucial. Clinical deterioration is often preceded by changes in vital signs, which are typically measured thrice a day by a nurse. However, intermittent measurements may delay recognizing clinical deterioration. Continuous vital parameter monitoring may lead to earlier recognition and management of complications and reduce nursing workload.
    OBJECTIVE: To compare vital parameter measurements between ward nurses and a wireless continuous monitoring system (Sensium® wireless patch) and assess whether this patch can detect clinical deterioration earlier in patients with complications in the first postoperative week.
    METHODS: Vital parameters (heart rate, respiratory rate, and temperature) were collected in patients undergoing an oncological resection of the liver, colorectal, or pancreas. Sensium® patch measurements were compared to nurses\' measurements to assess the percentages of discordant measurements. In patients with complications in the first postoperative week, time discrepancies between nurses and Sensium® patch measurements were identified in cases of clinical deterioration (respiratory rate ≥15/min, heart rate ≥100/min, and temperature ≥38°C).
    RESULTS: Among 227 patients, 22% of the patients experienced complications. Nurse and Sensium® measurements were discrepant in 586/2272 measurements (26%). In 506/586 discrepancies (86%), this was due to the respiratory rate (difference ≥4/min). Compared to nurses, the Sensium® patch detected an elevated respiratory rate 14 h earlier and heart rate 2 h earlier within complications in the first postoperative week. For temperature, no difference was observed.
    CONCLUSIONS: Continuous monitoring with the Sensium® wireless patch holds promise for earlier recognition of complications in patients who underwent major oncological abdominal surgery.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    Traditional surgical treatment of widespread purulent peritonitis has some disadvantages that emphasizes the need for new approaches to postoperative care. The authors present successful treatment of diffuse purulent peritonitis using a combination of \'open abdomen\' technology and VAC therapy. This approach reduces abdominal inflammation and intra-abdominal pressure. Combination of \'open abdomen\' technology and VAC therapy provides effective control of inflammation and stabilization of patients with purulent peritonitis.
    Широко используемый традиционный метод хирургического лечения пациентов с распространенным гнойным перитонитом имеет ряд значительных недостатков, что подчеркивает необходимость внедрения новых подходов к послеоперационному уходу. В статье представлено описание клинического случая, наглядно демонстрирующего успешное лечение разлитого гнойного перитонита с помощью комплексного метода, объединяющего технологию «открытый живот» и VAC-терапию. Этот подход способствует устойчивому снижению воспалительных процессов в брюшной полости и улучшению показателей внутрибрюшного давления. Комбинация метода «открытый живот» и VAC-терапии обеспечивает эффективное управление воспалением и стабилизацию пациентов с гнойным перитонитом.
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  • 文章类型: Journal Article
    背景:嗜麦芽窄食单胞菌,多重耐药革兰氏阴性菌(GNB),是一种新兴的医院病原体。本研究评估了腹部手术后外科重症监护病房(SICU)患者GNB感染的临床结局,重点研究嗜麦芽窄食链球菌和其他GNBs之间的差异,包括铜绿假单胞菌.
    方法:对2010年至2020年高雄长庚纪念医院SICU患者进行了回顾性研究,这些患者在腹部手术后出现GNB感染。
    结果:442名患者,237人患有嗜麦芽链球菌,205人患有非S。嗜麦芽异株GNB感染(包括81例铜绿假单胞菌)。总死亡率为44.5%,嗜麦芽窄食链球菌感染是GNB感染患者死亡率的重要因素。嗜麦芽窄食链球菌患者机械通气和SICU停留时间较长,30天死亡率为35.4%,高于非S。嗜麦芽异菌GNB(22.9%)和铜绿假单胞菌(21%)组。与非S相比,嗜麦芽嗜血杆菌组的住院死亡率也较高(53.2%)。嗜麦芽虫组GNB(34.6%)和铜绿假单胞菌组(29.6%)。获得嗜麦芽异型链球菌的危险因素包括较高的序贯器官衰竭评估评分和先前使用广谱抗生素。年纪大了,多微生物感染,胆红素升高与嗜麦芽嗜血杆菌患者30日死亡率增加相关.
    结论:S.腹部手术后患者的嗜麦芽桃体感染与死亡率高于非S。嗜麦芽菌GNB和铜绿假单胞菌感染,强调早期诊断和治疗以改善预后的必要性。
    BACKGROUND: Stenotrophomonas maltophilia, a multidrug-resistant gram-negative bacteria (GNB), is an emerging nosocomial pathogen. This study assessed the clinical outcomes of GNB infections in surgical intensive care unit (SICU) patients post-abdominal surgery, focusing on the differences between S. maltophilia and other GNBs, including Pseudomonas aeruginosa.
    METHODS: A retrospective study was conducted on SICU patients at Kaohsiung Chang Gung Memorial Hospital from 2010 to 2020, who developed GNB infections following abdominal surgery.
    RESULTS: Of 442 patients, 237 had S. maltophilia and 205 had non-S. maltophilia GNB infections (including 81 with P. aeruginosa). The overall mortality rate was 44.5%, and S. maltophilia infection emerged as a significant contributor to the mortality rate in patients with GNB infections. S. maltophilia patients had longer mechanical ventilation and SICU stays, with a 30-day mortality rate of 35.4%, higher than the non-S. maltophilia GNB (22.9%) and P. aeruginosa (21%) groups. In-hospital mortality was also higher in the S. maltophilia group (53.2%) compared to the non-S. maltophilia GNB (34.6%) and P. aeruginosa groups (29.6%). Risk factors for acquiring S. maltophilia included a higher Sequential Organ Failure Assessment score and prior broad-spectrum antibiotics use. Older age, polymicrobial infections, and elevated bilirubin were associated with increased 30-day mortality in S. maltophilia patients.
    CONCLUSIONS: S. maltophilia infections in post-abdominal surgery patients are linked to higher mortality than non-S. maltophilia GNB and P. aeruginosa infections, emphasizing the need for early diagnosis and treatment to improve outcomes.
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  • 文章类型: Journal Article
    背景:保持向组织的充足的氧供应对于维持器官功能是基本的。然而,我们在腹部手术期间识别高危人群和及时识别组织灌注不足的能力有限.为了解决这个问题,我们的目标是开发一种新的灌注监测方法,该方法可在外科手术过程中使用,并帮助外科医生做出决策.
    方法:在本实验猪研究中,13名受试者被随机分配一个感兴趣的器官[胃(n=3),升结肠(n=3),直肠(n=3),和脾脏(n=3)]。基线灌注记录后,使用高频,低剂量推注与体重调整(0.008mg/kg)ICG,人工完全闭塞器官供血动脉,导致靶器官灌注不足.在整个实验条件下进行连续的器官灌注监测。
    结果:手动封堵预选器官供血动脉后,外周动脉供应的闭塞转化为大多数器官的振荡信号立即降低(3/3心室,3/3升结肠,3/3直肠,2/3脾)。中央动脉供应的阻塞导致心室中的振荡曲线进一步减少或完全消失(3/3),升结肠(3/3),直肠(3/3),和脾脏(1/3)。
    结论:使用高频率的连续器官灌注监测,低剂量ICG推注方案可以实时检测器官灌注不足。
    BACKGROUND: Preserving sufficient oxygen supply to the tissue is fundamental for maintaining organ function. However, our ability to identify those at risk and promptly recognize tissue hypoperfusion during abdominal surgery is limited. To address this problem, we aimed to develop a new method of perfusion monitoring that can be used during surgical procedures and aid surgeons\' decision-making.
    METHODS: In this experimental porcine study, thirteen subjects were randomly assigned one organ of interest [stomach (n = 3), ascending colon (n = 3), rectum (n = 3), and spleen (n = 3)]. After baseline perfusion recordings, using high-frequency, low-dose bolus injections with weight-adjusted (0.008 mg/kg) ICG, organ-supplying arteries were manually and completely occluded leading to hypoperfusion of the target organ. Continuous organ perfusion monitoring was performed throughout the experimental conditions.
    RESULTS: After manual occlusion of pre-selected organ-supplying arteries, occlusion of the peripheral arterial supply translated in an immediate decrease in oscillation signal in most organs (3/3 ventricle, 3/3 ascending colon, 3/3 rectum, 2/3 spleen). Occlusion of the central arterial supply resulted in a further decrease or complete disappearance of the oscillation curves in the ventricle (3/3), ascending colon (3/3), rectum (3/3), and spleen (1/3).
    CONCLUSIONS: Continuous organ-perfusion monitoring using a high-frequency, low-dose ICG bolus regimen can detect organ hypoperfusion in real-time.
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  • 文章类型: Journal Article
    背景:进行范围审查是为了确定合并症评估的方法,并评估其在预测接受选择性腹部手术的老年患者癌症治疗结果中的意义。
    方法:OvidMEDLINE,Embase,中部,WebofScience,在ClinicalTrials.gov和EuropeanTrialsRegister中搜索了符合条件的研究,以调查合并症对65岁以上患者的各种术后结局的影响。对调查结果进行了叙述性报道。
    结果:该综述确定了40项研究,共有59,612名患者,使用八种不同的共病评估方法。使用最多的是Charlson合并症指数(60%的研究)和特定合并症的存在(38%)。没有研究提供选择特定合并症措施的理由。大多数纳入的研究报告了短期结果(75%),如术后并发症(43%)和死亡率(18%)作为主要临床终点。研究结果不一致。
    结论:关于合并症措施的选择及其在术后预后预测中的作用仍未达成共识。还需要进一步努力开发新的,精心设计,更有效的合并症评估工具。
    BACKGROUND: The scoping review was performed to identify methods of comorbidity assessment and to evaluate their significance in predicting the results of treatment of older patients undergoing elective abdominal surgeries for cancer.
    METHODS: Ovid MEDLINE, Embase, CENTRAL, Web of Science, ClinicalTrials.gov and European Trials Register were searched for eligible studies investigating the impact of comorbidity on various postoperative outcomes of patients aged ≥65. Findings were narratively reported.
    RESULTS: The review identified 40 studies with a total population of 59,612 patients, using eight different methods of comorbidity assessment. The most used was Charlson Comorbidity Index (60 % of studies) and presence of specific comorbid conditions (38 %). No study provided rationale for the choice of specific comorbidity measure. Most of the included studies reported short-term results (75 %), such as postoperative complications (43 %) and mortality (18 %) as main clinical endpoint. The results were inconsistent across the studies.
    CONCLUSIONS: There is still no consensus regarding the choice of comorbidity measures and their role in postoperative outcome prediction. Further efforts are needed to develop new, well-designed, more effective comorbidity assessments tools.
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