muscle strength

肌肉力量
  • 文章类型: Journal Article
    背景技术篮球是一项具有全球影响力和公认的大联盟的运动。并且是在高性能运动员水平上进行改进的研究和分析最多的运动之一。提高篮球运动员的跳跃高度是提高运动员运动成绩的重要因素。材料和方法本研究旨在确定流量限制的低强度训练与偏心运动方案对业余运动员的影响。18名年龄在16-45岁之间的业余篮球运动员分为2组:A组由9名参与者组成,他们进行了低强度训练,并进行了流量限制(40%强度),并在the区施加了200mmHg的阻塞,B组由9名参与者组成,他们在腓肠肌上进行了偏心运动。进行了人体测量评估,包括对努力的感知,运动范围(ROM),肌肉力量强度,用跳跃平台测量跳跃的力量。结果观察到明显的变化有利于A组的右背屈,平均差(MD)=-2.444(P=0.018);在95%置信区间(CI)下,左背屈时MD=-2.778(P=0.027),左脚周长变量MD=-0.667(P=0.026);而垂直跳跃有利于B组,MD=-2.899(P=0.006)。结论流量限制和偏心运动方案的低强度训练均可有效改善跳跃表现。2个研究组的跳跃高度和ROM显着改善。
    BACKGROUND Basketball is a sport with a global impact and recognized major leagues, and is one of the most studied and analyzed sports for improvement at the level of the high-performance athlete. Increasing the jump height of basketball players is an essential factor for high athletic performance. MATERIAL AND METHODS This study aimed to identify the effect of low-intensity training with flow restriction versus the eccentric exercise protocol on amateur athletes. Eighteen amateur basketball players aged 16-45 years were divided into 2 groups: Group A consisted of 9 participants with low-intensity training with flow restriction (40% intensity) with 200 mmHg occlusion applying flow restriction bands in the popliteal area, while Group B consisted of 9 participants who performed an eccentric exercises protocol on the gastrocnemius. An anthropometric evaluation was applied, which consisted of perception of effort, range of movement (ROM), muscle strength intensity, and the power of the jump measured with a jump platform. RESULTS Notable changes were observed in favor of Group A for the right dorsiflexion, with mean difference (MD)=-2.444 (P=0.018); left dorsiflexion with MD=-2.778 (P=0.027) and left foot perimeter variable with MD=-0.667 (P=0.026) at 95% confidence interval (CI); while the vertical jump was in favor of Group B, with MD=-2.899 (P=0.006). CONCLUSIONS Low-intensity training with flow restriction and eccentric exercise protocol were both effective in improving jumping performance. A significant improvement was shown in the jump height and ROM of the 2 study groups.
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  • 文章类型: Journal Article
    目的:关于低肌肉质量和低肌肉力量与糖尿病的联合和独立关联的证据是有限的和混合的。该研究旨在确定肌肉参数(肌肉质量,力量,质量,和肌肉减少症)和肌肉减少症肥胖伴糖尿病,以及之前未研究过的炎症的中介作用.
    方法:这项研究纳入了来自2023年中国国家健康调查(CNHS)的13,420名成年人和来自2011-2014年国家健康和营养调查(NHANES)的5380名成年人。在CNHS中使用生物电阻抗分析(BIA)确定肌肉质量,和NHANES中的全身双X射线吸收法(DXA)。使用数字手测力计评估肌肉力量。采用多因素logistic回归模型评价肌肉参数和肌少症肥胖与糖尿病的关系。使用血细胞计数和两个全身炎症指数(血小板与淋巴细胞比率(PLR)和系统炎症反应指数(SIRI))评估炎症状态。进行中介分析以检查炎症在这些关联中的作用。
    结果:肌肉质量和力量不足与糖尿病独立相关。低肌肉质量与糖尿病风险升高相关。与单独的低肌肉力量或单独的质量相比,肌肉减少症与糖尿病有更强的关联(CNHS,优势比(OR)=1.93,95%置信区间(CI):1.64-2.27;NHANES,OR=3.80,95CI:2.58-5.58)。与单纯肥胖或肌少症的参与者相比,患有肌少症的参与者患糖尿病的风险更高(CNHS,OR=2.21,95CI:1.72-2.84;NHANES,OR=6.06,95CI:3.64-10.08)。肌肉参数与糖尿病之间的关联部分由炎症介导(介导比例:1.99%-36.64%,P<0.05)。
    结论:肌肉质量和肌肉力量低下与糖尿病独立或共同相关,炎症可能是这种关联的潜在机制。此外,肌肉减少症和肥胖的协同作用可显著增加糖尿病风险.
    OBJECTIVE: The evidence for joint and independent associations of low muscle mass and low muscle strength with diabetes is limited and mixed. The study aimed to determine the associations of muscle parameters (muscle mass, strength, quality, and sarcopenia) and sarcopenia obesity with diabetes, and the previously unstudied mediating effect of inflammation.
    METHODS: A total of 13,420 adults from the 2023 China National Health Survey (CNHS) and 5380 adults from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) were included in this study. Muscle mass was determined using bioelectrical impedance analysis (BIA) in the CNHS, and whole-body dual X-ray absorptiometry (DXA) in the NHANES. Muscle strength was assessed using digital hand dynamometer. Multivariate logistic regression models were used to evaluate the associations of muscle parameters and sarcopenia obesity with diabetes. Inflammatory status was assessed using blood cell counts and two systemic inflammation indices (platelet-to-lymphocyte ratio (PLR) and system inflammation response index (SIRI)). Mediation analysis was conducted to examine inflammation\'s role in these associations.
    RESULTS: Low muscle mass and strength were independently related to diabetes. Low muscle quality was associated with elevated diabetes risk. Sarcopenia has a stronger association with diabetes compared to low muscle strength alone or mass alone (CNHS, odds ratio (OR) = 1.93, 95 % confidence interval (CI):1.64-2.27; NHANES, OR = 3.80, 95 %CI:2.58-5.58). Participants with sarcopenia obesity exhibit a higher risk of diabetes than those with obesity or sarcopenia alone (CNHS, OR = 2.21, 95 %CI:1.72-2.84; NHANES, OR = 6.06, 95 %CI:3.64-10.08). Associations between muscle parameters and diabetes were partially mediated by inflammation (mediation proportion: 1.99 %-36.64 %, P < 0.05).
    CONCLUSIONS: Low muscle mass and muscle strength are independently or jointly associated with diabetes, and inflammation might be a potential mechanism underlying this association. Furthermore, the synergistic effects of sarcopenia and obesity could significantly increase diabetes risk.
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  • 文章类型: Journal Article
    股四头肌扭矩发展率(RTD)和扭矩稳定性是评估爆炸强度和在持续一段时间内控制力的能力的有价值的指标。这可以为膝关节功能的临床评估提供信息。尽管它们广泛使用,衡量这些指标的标准化方法存在显著差距,这限制了它们在比较不同研究和人群结果方面的效用。为了弥补这些差距,我们评估了采样率的影响,信号滤波,以及RTD的转矩起始检测和转矩稳定。27名具有原发性前交叉韧带重建病史的参与者(N=27(11男/16女),年龄=23±8岁,体重指数=26±4kg/m2)和32名对照参与者(N=32(13男/19女),年龄=23±7岁,身体质量指数=23±3kg/m2)进行了等轴测股四头肌强度测试,在等速测功机上以2222Hz的频率收集数据。扭矩时间信号被下采样到大约100和1000Hz,并使用低通处理,零滞后巴特沃斯滤波器的截止频率范围跨越10-200赫兹。用于检测扭矩开始的阈值定义为0.1Nm,1Nm,5nm。RTD在0到100ms之间,0和200ms,计算了40-160毫秒,以及绝对和相对转矩的稳定性。通过将所有结果与计算的“黄金标准”值进行比较来计算相对差异,采样率为2222Hz,低通滤波器的截止频率为150Hz,和1Nm的扭矩开始,并利用线性混合模型进行比较。而所有信号收集和处理参数的组合达到了统计学意义(p<0.05),这些差异在受伤和控制肢体之间是一致的。此外,临床相关差异(+/-10%)主要通过扭矩开始检测方法观察到,并且主要在0-100ms之间影响RTD.尽管RTD和扭矩稳定性的测量通常对不同的信号收集和处理参数具有鲁棒性,扭矩起始的选择应仔细考虑,尤其是在早期RTD评估中,时间较短。
    Quadriceps rate of torque development (RTD) and torque steadiness are valuable metrics for assessing explosive strength and the ability to control force over a sustained period of time, which can inform clinical assessments of knee function. Despite their widespread use, there is a significant gap in standardized methodology for measuring these metrics, which limits their utility in comparing outcomes across different studies and populations. To address these gaps, we evaluated the influence of sampling rates, signal filtering, and torque onset detection on RTD and torque steadiness. Twenty-seven participants with a history of a primary anterior cruciate ligament reconstruction (N = 27 (11 male/16 female), age = 23 ± 8 years, body mass index = 26 ± 4 kg/m2) and thirty-two control participants (N = 32 (13 male/19 female), age = 23 ± 7 years, body mass index = 23 ± 3 kg/m2) underwent isometric quadriceps strength testing, with data collected at 2222 Hz on an isokinetic dynamometer. The torque-time signal was downsampled to approximately 100 and 1000 Hz and processed using a low-pass, zero-lag Butterworth filter with a range of cutoff frequencies spanning 10-200 Hz. The thresholds used to detect torque onset were defined as 0.1 Nm, 1 Nm, and 5 Nm. RTD between 0 and 100 ms, 0 and 200 ms, and 40-160 ms was computed, as well as absolute and relative torque steadiness. Relative differences were computed by comparing all outcomes to the \"gold standard\" values computed, with a sampling rate of 2222 Hz, a cutoff frequency in the low-pass filter of 150 Hz, and torque onset of 1 Nm, and compared utilizing linear mixed models. While all combinations of signal collection and processing parameters reached statistical significance (p < 0.05), these differences were consistent between injured and control limbs. Additionally, clinically relevant differences (+/-10%) were primarily observed through torque onset detection methods and primarily affected RTD between 0 and 100 ms. Although measurements of RTD and torque steadiness were generally robust against diverse signal collection and processing parameters, the selection of torque onset should be carefully considered, especially in early RTD assessments that have shorter time epochs.
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  • 文章类型: Journal Article
    运动是一种前线干预措施,可提高低力量水平或疾病患者的功能能力并减轻疼痛和残疾。然而,缺乏经过验证的基于现场的测试来检查初始状态,更重要的是,控制过程并对负载进行量身定制的调整,强度,和恢复。我们的目的是确定次最大值的重测可靠性,在医学诊断为慢性下腰痛的中年人(48±13岁)和健康同龄人(n=35)中,使用便携式力传感器评估躯干稳定肌肉的力量。参与者完成了两次阻力带练习的两次次最大渐进式测试(单侧行和Pallof按),由5秒保持的收缩组成,逐渐增加负荷。当由于补偿移动而偏离初始位置时,测试停止。使用便携式力传感器(应变仪)实时监测躯干肌肉力量(CORE肌肉)。结果显示,两种测试都高度可靠(类内相关性[ICC]>0.901),并且两组的误差和变异系数(CV)都很低。特别是,腰背痛患者在单侧行测试中的误差为14-19N(CV=9-12%),在Pallof按压中的误差为13-19N(CV=8-12%).在测试期间或之后没有报告不适或疼痛。这两个易于使用和基于技术的测试结果在一个可靠和客观的筛选工具,以评估中年人的力量和躯干稳定性慢性腰痛,考虑测量误差<20N。这种贡献可能对改善腰椎损伤或疾病患者的康复或体育锻炼的个性化和控制产生影响。
    Exercise is a front-line intervention to increase functional capacity and reduce pain and disability in people with low strength levels or disorders. However, there is a lack of validated field-based tests to check the initial status and, more importantly, to control the process and make tailored adjustments in load, intensity, and recovery. We aimed to determine the test-retest reliability of a submaximal, resistance-band test to evaluate the strength of the trunk stability muscles using a portable force sensor in middle-aged adults (48 ± 13 years) with medically diagnosed chronic low back pain and healthy peers (n = 35). Participants completed two submaximal progressive tests of two resistance-band exercises (unilateral row and Pallof press), consisting of 5 s maintained contraction, progressively increasing the load. The test stopped when deviation from the initial position by compensation movements occurred. Trunk muscle strength (CORE muscles) was monitored in real time using a portable force sensor (strain gauge). Results revealed that both tests were highly reliable (intra-class correlation [ICC] > 0.901) and presented low errors and coefficients of variation (CV) in both groups. In particular, people with low back pain had errors of 14-19 N (CV = 9-12%) in the unilateral row test and 13-19 N (CV = 8-12%) in the Pallof press. No discomfort or pain was reported during or after the tests. These two easy-to-use and technology-based tests result in a reliable and objective screening tool to evaluate the strength and trunk stability in middle-aged adults with chronic low back pain, considering an error of measurement < 20 N. This contribution may have an impact on improving the individualization and control of rehabilitation or physical training in people with lumbar injuries or disorders.
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  • 文章类型: Journal Article
    这项横断面研究旨在检查身体活动各个方面的关联,包括强度,持续时间,type,和目的,与相位角(PhA),健康的客观指标,在按性别分层后的韩国成年人中。2022年韩国国家健康和营养检查调查数据一个全国性的,代表,以人口为基础的调查,被使用。总的来说,3996名参与者被纳入研究。参与者自我报告他们每周的强度,频率,参与体育活动的持续时间。根据性别特异性平均值将PhA分为两组。采用多因素logistic回归分析研究体力活动与PhA,并进行比例几率逻辑回归分析,以确定体力活动与PhA不同亚类之间的关联。与不活动的身体活动相比,充分活跃的有氧身体活动与PhA之间存在正相关(充分活跃,男性:比值比=1.952,95%置信区间=1.373-2.776;女性:比值比=1.333,95%置信区间=1.019-1.745)。当有氧运动伴随着肌肉强化活动时,这种联系得到了进一步加强(与肌肉强化活动充分活跃,男性:aOR=2.318,95%CI=1.512-3.554;女性:aOR=1.762,95%CI=1.215-2.556)和高强度活动(足够活跃,足够的高强度活动,男性:aOR=2.785,95%CI=1.647-4.709;女性:aOR=2.505,95%CI=1.441-4.356),并且当休闲时间体育活动多于职业体育活动时(足够活跃,休闲时间体育活动更多,男性:aOR=2.158,95%CI=1.483-3.140;女性:aOR=1.457,95%CI=1.078-1.969)。此外,对于体力活动不充分的男性,包含肌肉强化活动的PhA值有显著差异(aOR=2.679,95%CI=1.560-4.602).对于具有高度活跃体力活动的女性(aOR=1.521,95%CI=1.068-2.166),包含肌肉强化和高强度活动与较高的PhA值显着相关。这项研究可用于为更好的健康计划提供具体建议,并可以改变人们对只有职业体力活动就足够的看法。这项研究还表明,PhA可用于个性化的健康评估。
    This cross-sectional study aimed to examine the association of various aspects of physical activity, including intensity, duration, type, and purpose, with the phase angle (PhA), an objective indicator of health, in Korean adults after stratification by sex. Data from the 2022 Korean National Health and Nutrition Examination Survey, a nationwide, representative, population-based survey, were used. In total, 3996 participants were included in the study. Participants self-reported their weekly intensity, frequency, duration of engagement in physical activity. PhA was categorized into two groups on the basis of sex-specific averages. Multiple logistic regression analysis was used to investigate the relationship between physical activity and PhA, and proportional odds logistic regression analysis was performed to determine the association between physical activity and different subclasses of PhA. A positive association was found between sufficiently active aerobic physical activity and PhA compared with inactive physical activity (sufficiently active, male: odds ratio = 1.952, 95% confidence interval = 1.373-2.776; female: odds ratio = 1.333, 95% confidence interval = 1.019-1.745). This association was further strengthened when aerobic physical activity was accompanied by muscle-strengthening activity (sufficiently active with muscle-strengthening activity, male: aOR = 2.318, 95% CI = 1.512-3.554; female: aOR = 1.762, 95% CI = 1.215-2.556) and vigorous-intensity activities (sufficiently active with sufficient vigorous-intensity activity, male: aOR = 2.785, 95% CI = 1.647-4.709; female: aOR = 2.505, 95% CI = 1.441-4.356) and when there was more leisure-time physical activity than occupational physical activity (sufficiently active with more leisure-time physical activity, male: aOR = 2.158, 95% CI = 1.483-3.140; female: aOR = 1.457, 95% CI = 1.078-1.969). Furthermore, the inclusion of muscle-strengthening activity made a significant difference in the values of PhA for males with insufficiently active physical activity (aOR = 2.679, 95% CI = 1.560-4.602). For females with highly active physical activity (aOR = 1.521, 95% CI = 1.068-2.166), the inclusion of muscle-strengthening and vigorous-intensity activities were significantly associated with higher values for PhA. This study can be utilized to provide specific suggestions for better health programs and can change perception that only occupational physical activity is enough. This study also indicated that PhA can be used for personalized health assessments.
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  • 文章类型: Journal Article
    动物来源的乳清蛋白(WPr)是消费者中最受欢迎的蛋白质补充剂,并已被证明可以改善肌肉质量和力量。然而,由于过敏,饮食限制/个人选择,不断增长的需求,替代蛋白质来源是必要的。久坐的成年人被随机分为豌豆蛋白(PPr)或WPr,并每周进行84天的阻力训练计划。全身肌肉力量(WBMS)的变化,包括手柄,下半身,和上身力量,身体成分,和产品感知进行了评估。安全性结果包括不良事件,生命体征,临床化学,和血液学。WBMS的变化没有显著差异,肌肉质量,或PPr和WPr组之间的产品感知和可爱度评分。补充PPr的参与者在补充84天后WBMS改善了16.1%(p=0.01),而服用WPr的患者则提高了11.1%(p=0.06)。两种研究产品在登记人群中均安全且耐受性良好。在健康久坐的成年人群体中,与阻力训练计划相结合,补充84天的PPr可改善与WPr相当的力量和肌肉质量。PPr可以被认为是动物来源的WPr的可行替代品,而不会牺牲肌肉增益和产品享受。
    Animal-sourced whey protein (WPr) is the most popular protein supplement among consumers and has been shown to improve muscle mass and strength. However, due to allergies, dietary restrictions/personal choices, and growing demand, alternative protein sources are warranted. Sedentary adults were randomized to pea protein (PPr) or WPr in combination with a weekly resistance training program for 84 days. Changes in whole-body muscle strength (WBMS) including handgrip, lower body, and upper body strength, body composition, and product perception were assessed. The safety outcomes included adverse events, vital signs, clinical chemistry, and hematology. There were no significant differences in the change in WBMS, muscle mass, or product perception and likability scores between the PPr and WPr groups. The participants supplemented with PPr had a 16.1% improvement in WBMS following 84 days of supplementation (p = 0.01), while those taking WPr had an improvement of 11.1% (p = 0.06). Both study products were safe and well-tolerated in the enrolled population. Eighty-four days of PPr supplementation resulted in improvements in strength and muscle mass comparable to WPr when combined with a resistance training program in a population of healthy sedentary adults. PPr may be considered as a viable alternative to animal-sourced WPr without sacrificing muscular gains and product enjoyment.
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  • 文章类型: Journal Article
    背景/目标:COVID-19后病症可通过各种症状表现,如呼吸困难,认知障碍,和疲劳,与这些症状相关的机制,特别是那些与疲劳有关的,仍然需要进一步澄清。因此,我们的目的是评估COVID-19后病情和持续性疲劳患者的临床和生理变量.方法:COVID-19感染后一年,对患者进行了全面评估,包括全血细胞计数,代谢小组,完整的肺活量测定,和呼吸困难的评估,生活质量,焦虑和抑郁,物理能力,身体成分,肌肉力量,合并症,和药物。参与者分为两组:G1-疲劳和G2-非疲劳。结果:包括77例患者(53%为女性;55±11.8岁),37在G1和40在G2。至于临床标志物和疾病症状,那些有持续性疲劳症状的人,更大的呼吸困难感觉[BDI评分:7.5(6-9)与12(9-12)p<0.001;mMRC评分:1(1-2)与0(0-1),p=0.002],生活质量较差[SGRQ总分:1404(1007-1897)vs.497(274-985);p<0.001],更高水平的焦虑[HADS-A评分:8(5-9)与3(0.5-4);p<0.001],外周和吸气肌肉力量[手握力量:34(28-40)与40(30-46.5)kgf,p=0.044;MIP:-81±31vs.-111±33mmHg,观察到p<0.001)]。结论:持续性疲劳者表现出更大的呼吸困难感,更高水平的焦虑,减少外周和吸气肌肉力量,以及对生活质量的更大损害。疲劳的严重程度受到生活质量恶化的影响,焦虑水平升高,外周肌肉力量下降。此外,较差的生活质量与较高的呼吸困难感有关,肌肉力量降低,身体能力下降。
    Background/Objectives: Post-COVID-19 condition can manifest through various symptoms such as dyspnea, cognitive disturbances, and fatigue, with mechanisms related to these symptoms, particularly those related to fatigue, still requiring further clarification. Therefore, our aim was to assess the clinical and physiological variables in patients with post-COVID-19 condition and persistent fatigue. Methods: After one year post-COVID-19 infection, the patients underwent a comprehensive evaluation, including a complete blood count, a metabolic panel, complete spirometry, and assessments of dyspnea, quality of life, anxiety and depression, physical capacity, body composition, muscle strength, comorbidities, and medications. The participants were categorized into two groups: G1-fatigue and G2-non-fatigue. Results: Seventy-seven patients (53% female; 55 ± 11.8 years) were included, 37 in G1 and 40 in G2. As for clinical markers and symptoms of illness, in those with persistent fatigue symptoms, a greater sensation of dyspnea [BDI score: 7.5 (6-9) vs. 12 (9-12), p < 0.001; mMRC score: 1 (1-2) vs. 0 (0-1), p = 0.002], worse quality of life [SGRQ total score: 1404 (1007-1897) vs. 497 (274-985); p < 0.001], higher levels of anxiety [HADS-A score: 8 (5-9) vs. 3 (0.5-4); p < 0.001], and a reduction in peripheral and inspiratory muscle strength [handgrip strength: 34 (28-40) vs. 40 (30-46.5) kgf, p = 0.044; MIP: -81 ± 31 vs. -111 ± 33 mmHg, p < 0.001)] were observed. Conclusions: Those with persistent fatigue exhibited a greater sensation of dyspnea, higher levels of anxiety, reduced peripheral and inspiratory muscle strength, and a greater impairment of quality of life. The severity of fatigue was influenced by the worsening quality of life, heightened anxiety levels, and decreased peripheral muscle strength. Additionally, the worse quality of life was associated with a higher sensation of dyspnea, lower muscle strength, and reduced physical capacity.
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  • 文章类型: Journal Article
    目的:据报道,通过生物电阻抗分析评估的骨骼肌的高细胞外水(ECW)与细胞内水(ICW)比率与肌肉力量的损失有关。然而,该指数对心力衰竭(HF)的有效性,这可能与水分布的变化有关,不清楚。
    结果:本研究涉及190例HF患者。测量上肢和下肢的总ECW和ICW,高ECW/ICW比率被定义为ECW/ICW比率高于中位数(男性≥0.636,女性≥0.652)。根据亚洲肌肉减少症工作组制定的标准,将低肌肉力量定义为握力降低。ECW/ICW比率高的患者的握力较低(21.1±8.1kg与27.6±9.3kg,P≤0.05)和6分钟步行距离(329±116mvs.440±114m)比ECW/ICW比值低的那些。ECW增加和/或ICW减少与更高的ECW/ICW比率和更低的握力相关(P<0.05)。在多变量逻辑回归分析中,高ECW/ICW比值和低骨骼肌质量与低肌力独立相关(P<0.05)。
    结论:肢体肌肉的ECW/ICW比率很高,也就是说,增加ECW和/或减少ICW的水不平衡,可用于评估HF患者的肌肉质量。
    OBJECTIVE: A high extracellular water (ECW) to intracellular water (ICW) ratio of skeletal muscle as assessed by bioelectrical impedance analysis is reportedly associated with loss of muscle strength. However, the validity of this index for heart failure (HF), which is likely associated with changes in the water distribution, is unclear.
    RESULTS: This study involved 190 patients with HF. The total ECW and ICW of both upper and lower extremities were measured, and a high ECW/ICW ratio was defined as an ECW/ICW ratio higher than the median (≥0.636 for men, ≥0.652 for women). Low muscle strength was defined as reduced handgrip strength according to the criteria established by the Asian Working Group for Sarcopenia. Patients with a high ECW/ICW ratio had a lower handgrip strength (21.1 ± 8.1 kg vs. 27.6 ± 9.3 kg, P ≤ 0.05) and 6 min walk distance (329 ± 116 m vs. 440 ± 114 m) than those with a low ECW/ICW ratio. An increasing ECW and/or decreasing ICW was associated with a higher ECW/ICW ratio and a lower handgrip strength (P < 0.05). In the multivariate logistic regression analysis, a high ECW/ICW ratio and low skeletal muscle mass were independently associated with low muscle strength (P < 0.05).
    CONCLUSIONS: A high ECW/ICW ratio in limb muscles, that is, the water imbalance of increasing ECW and/or decreasing ICW, is useful in assessing muscle quality in patients with HF.
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  • 文章类型: Journal Article
    背景:胶原蛋白,体内的关键蛋白质维持头发,随着人类年龄的增长,皮肤和骨骼的健康及其合成趋于减少。由于对纯素饮食的适应性增强,全世界对纯素胶原蛋白助洗剂的需求有所增加。
    目的:这项临床研究旨在评估不同剂量(2.5、5和10g)的纯素胶原蛋白助洗剂(VEGCOL™name)在成人参与者中的安全性和有效性。
    方法:共纳入66名受试者(22名受试者/剂),年龄30至50岁,63名受试者完成了这项研究。研究持续时间为60天。评估包括皮肤弹性的变化,水合作用,乌鸦的脚区域皱纹,细线,皮肤,Glogau皮肤年龄,疼痛评分的变化,肌肉力量和受试者对测试治疗使用的感知评估。
    结果:治疗60天后,头发生长率显着提高了45.01%,剂量2.5、5和10g分别为38.54%和50.37%,p<0.01。此外,用10g剂量观察到毛发密度和毛发厚度分别增加19.64%(p<0.0001)和20.51%(p<0.0001)。2.5g剂量导致皮肤光滑度增加33.03%(p<0.01),乌鸦足面积皱纹减少49.94%(p<0.0001),收缩时间减少21.71毫秒(p<0.05)。疼痛评分降低52.54%(p<0.001)。未报告任何不良事件。
    结论:素食主义者胶原蛋白助洗剂有效改善了多种与年龄有关的问题,例如皱纹,细线,关节痛,肌肉力量和头发生长。所有受访者都认为该产品有益于改善皮肤的美观性,头发,和指甲。研究结果支持使用纯素胶原蛋白助洗剂安全有效地促进更健康的皮肤,更强壮的肌肉,改善头发和指甲状况。
    BACKGROUND: Collagen, a key protein in the body maintains hair, skin and bone health and its production tends to decrease in synthesis as humans age. The demand for vegan collagen-builder has increased worldwide due to increased adaptability to vegan diet.
    OBJECTIVE: This clinical study was designed aim to evaluate the safety and efficacy of vegan collagen builder (VEGCOL™️) at different dosages (2.5, 5, and 10 g) in adult participants.
    METHODS: Total 66 subjects (22 subjects/dose) aged 30 to 50 years were enrolled, and 63 subjects completed the study. Duration of study was 60 days. Evaluations included change in skin elasticity, hydration, crow\'s feet area wrinkles, fine lines, skin, Glogau skin age, change in pain scale score, muscle strength and subject perception assessment about test treatment use.
    RESULTS: After 60 days of treatment, there was significant improvement in hair growth rate by 45.01%, 38.54% and 50.37% with p < 0.01 for doses 2.5, 5, and 10 g respectively. Additionally, 19.64% (p < 0.0001) and 20.51% (p < 0.0001) increase in hair density and hair thickness respectively was observed with 10 g dose. 2.5 g dose resulted in 33.03% (p < 0.01) increase in skin smoothness and 49.94% (p < 0.0001) decrease in crow\'s feet area wrinkles, decreased retraction time by 21.71 milliseconds (p < 0.05). 52.54% reduction in pain score (p < 0.001). No any adverse events were reported.
    CONCLUSIONS: Vegan collagen-builder effectively improved multiple age-related concerns such as wrinkles, fine lines, joint pain, muscle strength and hair growth. All respondents perceived the product as beneficial in improving the aesthetics of the skin, hair, and nails. The findings support the use of vegan collagen-builder as safe and efficacious in promoting healthier skin, stronger muscles, and improved hair and nail conditions.
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  • 文章类型: Journal Article
    与年龄相关的姿势过度后凸是胸椎前曲度的夸张表现,这损害了平衡,增加了老年人跌倒和骨折的风险。我们的目标是回顾老年人专用脊柱矫形器对该受试者的肌肉功能和后凸角度的影响。
    我们搜索了PubMed,Scopus,ISI知识网,ProQuest和Cochrane图书馆旨在确定相关研究,以评估脊柱矫形器对患有脊柱后凸畸形的老年受试者的肌肉功能和后凸角度的功效。使用Downs和Black量表进行质量评估。
    在18篇文章中描述了709名个体的结果,其中12项研究涉及RCT。148例患者使用矫形器后凸角度差异有统计学意义(SMD:-3.79,95%CI-7.02至-0.56,p<0.01)。除了一项研究,所有研究表明,当参与者佩戴脊柱矫形器时,背部肌肉力量显着增加,并且这种效果在长期随访中明显更好(MD:84.73;95%CIs,23.24至146.23;p<0.01)。在痛苦的结果中,矫形器带来的疗效大且显著(SMD:-1.66;95%CIs,-2.39至0.94;p<0.01)。
    脊柱矫形器可能是老年后凸畸形的有效治疗方法。然而,人数少,以及纳入研究的异质性,表明应进行更高质量的研究来验证后凸畸形的有效性和矫形器。
    与年龄相关的体位后凸畸形是胸椎前曲度的夸张表现,这损害了平衡,增加了老年人跌倒和骨折的风险。根据这篇综述的结果,老年特定的脊柱矫形器可能被推荐为老年后凸高患者的有效装置。脊柱矫形器处方对于健康从业者在计划治疗时考虑很重要。
    UNASSIGNED: Age-related postural hyper-kyphosis is an exaggerated anterior curvature of the thoracic spine, that impairs balance and increases the risk of falls and fractures in elderly subjects. Our objectives are to review the effect of elderly-specific spinal orthoses on muscle function and kyphosis angle in this subjects.
    UNASSIGNED: We searched PubMed, Scopus, ISI web of Knowledge, ProQuest and Cochrane library to identify relevant studies that assessed efficacy of spinal orthoses on muscle function and kyphosis angle of elderly subjects with elderly with hyper-kyphosis. Quality assessment was implemented using the Downs and Black scale.
    UNASSIGNED: Results for 709 individuals were described in 18 articles which 12 studies involved RCT. There was significant difference for kyphosis angle after use of orthosis of 148 participants (SMD: -3.79, 95% CI -7.02 to -0.56, p < 0.01). Except one study, all of studies showed significantly increased on the back muscle strength when the participants wore the spinal orthosis and this effect was significantly better in long-term follow up (MD: 84.73; 95% CIs, 23.24 to 146.23; p < 0.01). In the outcome of pain, the efficacy brought by orthosis was large and significant (SMD: -1.66; 95% CIs, -2.39 to 0.94; p < 0.01).
    UNASSIGNED: Spinal orthosis may be an effective treatment for elderly hyper-kyphosis. However, the small number, and heterogeneity of the included studies, indicate that higher-quality studies should be conducted to verify the effectiveness and orthosis in hyper-kyphosis.
    Age-related postural hyper kyphosis is an exaggerated anterior curvature of the thoracic spine, that impairs balance and increases the risk of falls and fractures in elderly subjects.Based on the findings of this review, elderly specific spinal orthoses may be recommended as effective device for elderly hyper kyphotic subjects.Spinal orthoses prescription is important for health practitioners to consider when planning treatment.
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