Abstract：
BACKGROUND: Collagen, a key protein in the body maintains hair, skin and bone health and its production tends to decrease in synthesis as humans age. The demand for vegan collagen-builder has increased worldwide due to increased adaptability to vegan diet.
OBJECTIVE: This clinical study was designed aim to evaluate the safety and efficacy of vegan collagen builder (VEGCOL™️) at different dosages (2.5, 5, and 10 g) in adult participants.
METHODS: Total 66 subjects (22 subjects/dose) aged 30 to 50 years were enrolled, and 63 subjects completed the study. Duration of study was 60 days. Evaluations included change in skin elasticity, hydration, crow\'s feet area wrinkles, fine lines, skin, Glogau skin age, change in pain scale score, muscle strength and subject perception assessment about test treatment use.
RESULTS: After 60 days of treatment, there was significant improvement in hair growth rate by 45.01%, 38.54% and 50.37% with p < 0.01 for doses 2.5, 5, and 10 g respectively. Additionally, 19.64% (p < 0.0001) and 20.51% (p < 0.0001) increase in hair density and hair thickness respectively was observed with 10 g dose. 2.5 g dose resulted in 33.03% (p < 0.01) increase in skin smoothness and 49.94% (p < 0.0001) decrease in crow\'s feet area wrinkles, decreased retraction time by 21.71 milliseconds (p < 0.05). 52.54% reduction in pain score (p < 0.001). No any adverse events were reported.
CONCLUSIONS: Vegan collagen-builder effectively improved multiple age-related concerns such as wrinkles, fine lines, joint pain, muscle strength and hair growth. All respondents perceived the product as beneficial in improving the aesthetics of the skin, hair, and nails. The findings support the use of vegan collagen-builder as safe and efficacious in promoting healthier skin, stronger muscles, and improved hair and nail conditions.
OBJECTIVE: This clinical study was designed aim to evaluate the safety and efficacy of vegan collagen builder (VEGCOL™️) at different dosages (2.5, 5, and 10 g) in adult participants.
METHODS: Total 66 subjects (22 subjects/dose) aged 30 to 50 years were enrolled, and 63 subjects completed the study. Duration of study was 60 days. Evaluations included change in skin elasticity, hydration, crow\'s feet area wrinkles, fine lines, skin, Glogau skin age, change in pain scale score, muscle strength and subject perception assessment about test treatment use.
RESULTS: After 60 days of treatment, there was significant improvement in hair growth rate by 45.01%, 38.54% and 50.37% with p < 0.01 for doses 2.5, 5, and 10 g respectively. Additionally, 19.64% (p < 0.0001) and 20.51% (p < 0.0001) increase in hair density and hair thickness respectively was observed with 10 g dose. 2.5 g dose resulted in 33.03% (p < 0.01) increase in skin smoothness and 49.94% (p < 0.0001) decrease in crow\'s feet area wrinkles, decreased retraction time by 21.71 milliseconds (p < 0.05). 52.54% reduction in pain score (p < 0.001). No any adverse events were reported.
CONCLUSIONS: Vegan collagen-builder effectively improved multiple age-related concerns such as wrinkles, fine lines, joint pain, muscle strength and hair growth. All respondents perceived the product as beneficial in improving the aesthetics of the skin, hair, and nails. The findings support the use of vegan collagen-builder as safe and efficacious in promoting healthier skin, stronger muscles, and improved hair and nail conditions.
摘要：
背景：胶原蛋白，体内的关键蛋白质维持头发，随着人类年龄的增长，皮肤和骨骼的健康及其合成趋于减少。由于对纯素饮食的适应性增强，全世界对纯素胶原蛋白助洗剂的需求有所增加。
目的：这项临床研究旨在评估不同剂量（2.5、5和10g）的纯素胶原蛋白助洗剂（VEGCOL™name）在成人参与者中的安全性和有效性。
方法：共纳入66名受试者（22名受试者/剂），年龄30至50岁，63名受试者完成了这项研究。研究持续时间为60天。评估包括皮肤弹性的变化，水合作用,乌鸦的脚区域皱纹，细线,皮肤,Glogau皮肤年龄，疼痛评分的变化，肌肉力量和受试者对测试治疗使用的感知评估。
结果：治疗60天后，头发生长率显着提高了45.01%，剂量2.5、5和10g分别为38.54%和50.37%,p<0.01。此外,用10g剂量观察到毛发密度和毛发厚度分别增加19.64%(p<0.0001)和20.51%(p<0.0001)。2.5g剂量导致皮肤光滑度增加33.03%(p<0.01)，乌鸦足面积皱纹减少49.94%(p<0.0001)，收缩时间减少21.71毫秒（p<0.05）。疼痛评分降低52.54%(p<0.001)。未报告任何不良事件。
结论：素食主义者胶原蛋白助洗剂有效改善了多种与年龄有关的问题，例如皱纹，细线,关节痛,肌肉力量和头发生长。所有受访者都认为该产品有益于改善皮肤的美观性，头发,和指甲。研究结果支持使用纯素胶原蛋白助洗剂安全有效地促进更健康的皮肤，更强壮的肌肉，改善头发和指甲状况。
目的：这项临床研究旨在评估不同剂量（2.5、5和10g）的纯素胶原蛋白助洗剂（VEGCOL™name）在成人参与者中的安全性和有效性。
方法：共纳入66名受试者（22名受试者/剂），年龄30至50岁，63名受试者完成了这项研究。研究持续时间为60天。评估包括皮肤弹性的变化，水合作用,乌鸦的脚区域皱纹，细线,皮肤,Glogau皮肤年龄，疼痛评分的变化，肌肉力量和受试者对测试治疗使用的感知评估。
结果：治疗60天后，头发生长率显着提高了45.01%，剂量2.5、5和10g分别为38.54%和50.37%,p<0.01。此外,用10g剂量观察到毛发密度和毛发厚度分别增加19.64%(p<0.0001)和20.51%(p<0.0001)。2.5g剂量导致皮肤光滑度增加33.03%(p<0.01)，乌鸦足面积皱纹减少49.94%(p<0.0001)，收缩时间减少21.71毫秒（p<0.05）。疼痛评分降低52.54%(p<0.001)。未报告任何不良事件。
结论：素食主义者胶原蛋白助洗剂有效改善了多种与年龄有关的问题，例如皱纹，细线,关节痛,肌肉力量和头发生长。所有受访者都认为该产品有益于改善皮肤的美观性，头发,和指甲。研究结果支持使用纯素胶原蛋白助洗剂安全有效地促进更健康的皮肤，更强壮的肌肉，改善头发和指甲状况。
