health benefits

健康益处
  • 文章类型: Journal Article
    背景:热带油如棕榈油和椰子油以其高饱和脂肪含量和烹饪多功能性而闻名。然而,他们的消费引发了关于他们健康益处和生产问题的辩论。这篇综述的目的是绘制与热带油消费相关的健康益处和挑战的现有证据。
    方法:遵循Arksey和O\'Malley进行范围审查的建议。PubMed,尺寸AI,中央,JSTOR谷歌,谷歌学者,和ProQuest数据库搜索相关论文。使用的预定关键字是消费“和”热带石油,\"以及\"健康益处\"或\"健康挑战\"和\"热带国家。“同行评审和以英文发表的灰色文献符合这篇评论的条件。
    结果:热带油,如棕榈油和椰子油,提供健康益处,包括增强眼部健康的必需维生素(A和E),增强免疫力,支持增长。他们还因在控制高血糖方面的作用而受到认可,肥胖,和胆固醇水平,同时提供抗氧化和抗炎特性。这些油具有伤口愈合能力,通常用于婴儿营养和传统烹饪。然而,长期和反复使用热带油高温可以降解维生素E,而过量摄入可能导致过量。健康问题包括氧化风险,糖尿病,癌症,冠心病,高血压,和丙烯酰胺的形成,由于生产挑战过度消费。其他问题包括肥胖,次优石油生产,误解,监管障碍,以及对替代脂肪的偏好。
    结论:这篇综述表明,热带油具有基本的健康益处,包括维生素和抗氧化特性,但带来重大的健康风险和生产挑战,特别是当暴露于高温和过量摄入时。关于热带地区热带油消费的准则对于规范其消费是必要的。
    BACKGROUND: Tropical oils such as palm and coconut oils are renowned for their high saturated fat content and culinary versatility. However, their consumption has sparked debate regarding their health benefits and production concerns. The purpose of this review was to map existing evidence on the health benefits and challenges associated with the consumption of tropical oils.
    METHODS: The recommendations for conducting a scoping review by Arksey and O\'Malley were followed. PubMed, Dimensions AI, Central, JSTOR Google, Google Scholar, and ProQuest databases were searched for relevant papers. The predetermined keywords used were Consumption\" AND \"Tropical oil,\" as well as \"Health benefits\" OR \"Health challenges\" AND \"Tropical Countries.\" Peer-reviewed and grey literature published in English were eligible for this review.
    RESULTS: Tropical oils, such as palm and coconut oils, provide health benefits including essential vitamins (A and E) that enhance ocular health, boost immunity, and support growth. They are also recognised for their role in managing high blood sugar, obesity, and cholesterol levels, while offering antioxidant and anti-inflammatory properties. These oils have wound-healing abilities and are commonly used in infant nutrition and traditional cooking. Nevertheless, prolonged and repeated use of tropical oils to high temperature can degrade vitamin E, whereas excessive intake may result in overdose. Health concerns include oxidative risks, diabetes, cancer, coronary heart disease, high blood pressure, and acrylamide formation due to production challenges excessive consumption. Additional issues include obesity, suboptimal oil production, misconceptions, regulatory obstacles, and preferences for alternative fats.
    CONCLUSIONS: This review suggest that tropical oils provide essential health benefits, including vitamins and antioxidant properties, but pose significant health risks and production challenges, particularly when exposed to high temperatures and through excessive intake. Guidelines on the consumption of tropical oils in the tropical regions are necessary to regulate their consumption.
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  • 文章类型: Journal Article
    提高电气化可行性对于减少非电能排放至关重要,从而提高空气质量和公共卫生。同时,气候减缓行动,如碳定价政策,具有缓解二氧化碳(CO2)和其他共同排放的空气污染物增加的巨大潜力。然而,气候政策与省级电气化可行性提高之间的相互作用仍不清楚,共同影响能源密集型行业的净零转型。在这里,我们将技术丰富的经济-能源-环境模型与中国的空气质量模型相结合,以检查健康状况,气候,以及2017年至2030年电气化可行性和气候政策大规模升级的经济影响。结果表明,推进电气化的可行性,再加上采取碳定价政策,可能有助于向电力主导的能源系统过渡。预计到2030年,电气化可行性的提高将使全国气候效益增加7-25%,健康效益增加5-14%。这些递增的好处,加上经济成本的降低,导致净收益增加22-68%。然而,区域性,电气化可行性的提高将导致某些省份的电力需求增加和电能生产的意外排放(例如,内蒙古)由于煤炭主导的电力系统。此外,在山西和陕西等主要产煤省份,电气化可行性的提高加剧了气候政策的负面经济影响。这项研究提供了定量见解,以了解改善电气化可行性如何重塑能源演变以及省级气候政策的收益成本概况。调查结果强调了在受影响和未受影响的省份之间精心设计的补偿计划以及在电力和其他最终用途部门之间协调减排的必要性。
    Improving electrification feasibility is essential for reducing emissions from non-electric energy sources, thereby enhancing air quality and public health. Concurrently, climate mitigation actions, such as carbon pricing policies, have significant potential to alleviate increasing carbon dioxide (CO2) and other co-emitted air pollutants. However, the interactions between climate policy and the improvement of electrification feasibility at the provincial level remain unclear, collectively impacting the net-zero transition of energy-intensive sectors. Here we combine a technologically rich economic-energy-environment model with air quality modeling across China to examine the health, climate, and economic implications of large-scale upgrades in electrification feasibility and climate policies from 2017 to 2030. The results indicate that advancing electrification feasibility, coupled with adopting carbon pricing policies, is likely to facilitate a transition towards electricity-dominant energy systems. Improved electrification feasibility is projected to yield a 7-25% increase in nationwide climate benefits and a 5-14% increase in health benefits by 2030. These incremental benefits, coupled with reduced economic costs, result in a 22-68% increase in net benefits. However, regionally, improvements in electrification feasibility will lead to heightened power demand and unintended emissions from electric energy production in certain provinces (e.g., Nei Mongol) due to the coal-dominated power system. Additionally, in major coal-producing provinces like Shanxi and Shaanxi, enhanced electrification feasibility exacerbates the negative economic impacts of climate policies. This study provides quantitative insights into how improving electrification feasibility reshapes energy evolution and the benefit-cost profile of climate policy at the provincial level. The findings underscore the necessity of a well-designed compensation scheme between affected and unaffected provinces and coordinated emission mitigation across the power and other end-use sectors.
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  • 文章类型: Journal Article
    萜类化合物是一类结构高度多样化的天然次生植物代谢产物,由异戊二烯单元(C-5)形成,与广泛的生物学特性有关,包括抗氧化剂,抗菌,抗炎,抗过敏,抗癌,抗转移,抗血管生成,和凋亡诱导,并考虑在食品中的潜在应用,化妆品,Pharmaceutical,和医疗行业。在植物中,萜类化合物在生长发育中发挥着多种基本功能。这篇评论给出了一个概述,强调萜类化合物的当前知识和我们对组织的理解的最新进展,regulation,以及核心和专门萜类代谢途径的多样化,并解决植物中挥发性和非挥发性专门萜类代谢产物的最重要功能。对植物衍生萜类化合物作为生物活性化合物可持续来源的不同方面的全面描述,它们的生物合成途径,归因于这些与健康促进作用相关的次级代谢物的几种生物学特性,以及它们在几个领域的潜在工业应用将被提供,以及新兴的绿色提取方法也将被讨论。此外,将强调这一框架内未来的研究前景。文献选择是利用国家医学图书馆进行的,PubMed,2010年至2024年期间的国际参考数据,使用关键词“萜类化合物”。共发现177633篇发表的论文,其中196篇原创论文和综述论文根据其科学可靠性标准被纳入本综述,其完整性,以及它们与所考虑主题的相关性。
    Terpenoids are a large class of natural secondary plant metabolites which are highly diverse in structure, formed from isoprene units (C-5), associated with a wide range of biological properties, including antioxidant, antimicrobial, anti-inflammatory, antiallergic, anticancer, antimetastatic, antiangiogenesis, and apoptosis induction, and are considered for potential application in the food, cosmetics, pharmaceutical, and medical industries. In plants, terpenoids exert a variety of basic functions in growth and development. This review gives an overview, highlighting the current knowledge of terpenoids and recent advances in our understanding of the organization, regulation, and diversification of core and specialized terpenoid metabolic pathways and addressing the most important functions of volatile and non-volatile specialized terpenoid metabolites in plants. A comprehensive description of different aspects of plant-derived terpenoids as a sustainable source of bioactive compounds, their biosynthetic pathway, the several biological properties attributed to these secondary metabolites associated with health-promoting effects, and their potential industrial applications in several fields will be provided, and emerging and green extraction methods will also be discussed. In addition, future research perspectives within this framework will be highlighted. Literature selection was carried out using the National Library of Medicine, PubMed, and international reference data for the period from 2010 to 2024 using the keyword \"terpenoids\". A total of 177,633 published papers were found, of which 196 original and review papers were included in this review according to the criteria of their scientific reliability, their completeness, and their relevance to the theme considered.
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  • 文章类型: Journal Article
    开发功能性食品是减轻全球结直肠癌日益增加的负担的有希望的策略。水果果渣,特别是富含多酚和花青素的苦莓和蓝莓,是功能性食品和营养食品的重要成分。我们的研究旨在评估苦莓和蓝莓果渣提取物对C2BBe1大肠癌细胞的抗炎和抗增殖作用,并探索潜在的信号通路。我们使用Folin-Ciocalteu方法和超高效液相色谱法分析了两种果渣提取物中的总多酚和花色苷,而抗氧化活性是通过2,2-二苯基-1-吡啶酰肼基自由基清除方法评估的。我们使用锥虫蓝排除法评估了体外抗炎和抗增殖作用,MTT和LDH测定,并评估p-Erk1/2,Akt-1,STAT1,STAT3,occludin,氧化蛋白质,和MDA-蛋白质加合物通过蛋白质印迹,以及37组炎症标志物的分析。苦莓提取物表现出较高的总多酚含量,花青素水平,和抗氧化活性相比,蓝莓提取物,然而,蓝莓提取物对C2BBe1细胞活力和增殖的影响更强。两种水果都诱导了以膜完整性丧失为特征的非炎性细胞死亡,有益于癌症治疗。我们的数据表明,chokeberry的细胞毒性可能是由Erk信号和Akt-1抑制介导的,而蓝莓独特地降低了occludin水平。这些浆果具有减轻癌症风险和增强治疗效果的潜力,是有希望的。保证对功能性食品开发的进一步调查。
    Developing of functional foods is a promising strategy to reduce the increasing burden of colorectal cancer worldwide. Fruit pomace, particularly polyphenol and anthocyanin-rich chokeberry and blueberry, is a valuable ingredient for functional foods and nutraceuticals. Our study aimed to evaluate the anti-inflammatory and antiproliferative effects of chokeberry and blueberry pomace extracts on C2BBe1 colorectal carcinoma cells and explore the underlying signaling pathways. We analyzed both pomace extracts for total polyphenols and anthocyanins using Folin-Ciocalteu method and ultra-performance liquid chromatography, while antioxidative activity was assessed via the 2,2-diphenyl-1-picrylhydrazyl radical scavenging method. We evaluated the in vitro anti-inflammatory and antiproliferative effects using trypan blue exclusion, MTT and LDH assays, and assessed protein levels of p-Erk1/2, Akt-1, STAT1, STAT3, occludin, oxidized proteins, and MDA-protein adducts through western blotting, as well as analysis of a 37-plex panel of inflammatory markers. Chokeberry extracts exhibited higher total polyphenol content, anthocyanin levels, and antioxidative activity compared to blueberry extracts, however, blueberry extracts effects on cell viability and proliferation in C2BBe1 cells were stronger. Both fruit pomaces induced non-inflammatory cell death characterized by membrane integrity loss, beneficial in cancer therapy. Our data suggests chokeberry\'s cytotoxicity may be mediated by Erk signaling and Akt-1 inhibition, while blueberry uniquely decreased occludin levels. These berries pomaces\' potential to mitigate cancer risks and enhance treatment efficacy is promising, warranting further investigation for functional foods development.
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  • 文章类型: Journal Article
    益生菌是对宿主具有有益作用的活酵母或细菌生物体。几种微生物表现出益生菌特性,最常见的类型是乳酸菌,双歧杆菌,孢子形成细菌,和一些酵母菌株.酿酒酵母变种。布拉氏酵母是最重要的益生菌酵母。然而,另一组食源性微生物,所谓的非酵母菌(NSY),最近进行了重新评估,并显示出在各个应用领域具有巨大的潜力,从食品发酵到人类和动物应用。NSY能够产生一系列生物活性化合物,如抗菌剂,甘露糖蛋白,酶,多不饱和脂肪酸,必需氨基酸,维生素,和β-葡聚糖,这增加了它们作为一类新的益生菌和/或抗生素替代品在畜牧业中的潜在应用。在这次审查中,我们的目标是强调NSY作为益生菌和天然抗菌剂改善动物健康的潜力和益处。此外,讨论了使用NSY作为抗生素的生物替代品来控制动物生产中的食源性病原体。
    Probiotics are live yeast or bacterial organisms that have beneficial effects on the host. Several microorganisms exhibit probiotic properties, the most common types being lactic acid bacteria, Bifidobacteria, spore-forming bacteria, and some yeast strains. Saccharomyces cerevisiae var. boulardii is the most important probiotic yeast species. However, another group of foodborne microorganisms, the so-called non-Saccharomyces yeasts (NSYs), has recently been re-evaluated and shown to have enormous potential in various fields of application, ranging from food fermentation to human and animal applications. NSYs are able to produce a range of bioactive compounds such as antimicrobials, mannoproteins, enzymes, polyunsaturated fatty acids, essential amino acids, vitamins, and β-glucans, which increases their potential applications as a new class of probiotics and/or alternatives to antibiotics in animal husbandry. In this review, we aim to highlight the potential and benefits of NSYs as probiotics and natural antimicrobials to improve animal health. Furthermore, the use of NSYs as biological alternatives to antibiotics to control foodborne pathogens in animal production is discussed.
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  • 文章类型: Journal Article
    菊花拉马特。(C.moorifolium),作为一种传统的观赏植物,它有多个值,包括可食用的,经济,营养甚至药用价值,它被用作草药和世界上新的食物资源。多糖是梭菌中的主要生物活性成分之一,具有各种健康益处,例如改善功能性便秘,改善结肠炎,抗糖基化,抗氧化剂,抗血管生成,免疫调节,益生元,和α-葡萄糖苷酶抑制活性。本文介绍了提取,净化,结构特征,健康益处,结构-活动关系,应用程序,并分析了主要相关研究存在的缺点。此外,总结了梭菌多糖对健康有益的潜在机制。本研究可为进一步研究和开发桑树多糖提供参考和方向。
    Chrysanthemum morifolium Ramat. (C. morifolium), as a traditional ornamental plant, it has multiple values, including edible, economic, nutritional and even medicinal values, which is used as herbal medicine and a new food resource in the world. Polysaccharides are one of the main bioactive components in C. morifolium, which have various health benefits such as improving functional constipation, improving colitis, anti-glycosylation, antioxidant, anti-angiogenesis, immunomodulation, prebiotic, and α-glucosidase inhibitory activities. This paper describes the extraction, purification, structural characteristics, health benefits, structural-activity relationships, applications, and analyses the shortcomings of the major relevant studies exist on C. morifolium polysaccharides. In addition, the potential mechanisms of the health benefits of C. morifolium polysaccharides were summarized. This study can provide reference and direction for further research and development of C. morifolium polysaccharides.
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  • 文章类型: Journal Article
    这篇文献综述提供了对Chaga蘑菇(Inonotusobalquus)的广泛探索,关注它们的植物化学成分,促进健康的属性,和行动机制。目的是提供Chaga在医药领域的重要性的最新概述,强调其在不同健康益处中的潜在作用。这篇评论强调了Chaga的非凡抗癌,抗氧化剂,抗糖尿病,抗炎,抗菌,和免疫调节特性。综合最近的发现,这项工作强调了Chaga在医药工业中的重要性,并为其药理潜力提供了有价值的见解。
    This literature review offers an extensive exploration of Chaga mushrooms (Inonotus obliquus), focusing on their phytochemical composition, health-promoting attributes, and mechanisms of action. The aim was to provide an up-to-date overview of Chaga\'s significance in the medicinal sector, emphasizing its potential role in diverse health benefits. The review highlights Chaga\'s remarkable anticancer, antioxidant, anti-diabetic, anti-inflammatory, antimicrobial, and immunomodulating properties. By synthesizing recent findings, this work underscores Chaga\'s importance in the medicinal industries and provides valuable insights into its pharmacological potential.
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  • 文章类型: Journal Article
    枣树的果实营养丰富,具有多种健康益处。中国是大枣的主要生产国,它现在在世界各地种植。大量研究已经证明了在枣树中发现的生物活性化合物的营养价值和潜在的健康优势。此外,枣树有显著的7000年的农业历史。枣属植物发展了丰富的基因库,使其成为宝贵的种质资源。不同的研究集中在枣果实的发育阶段,以确定收获的最佳时间,并评估其生物活性天然化合物或产物在发育过程中的变化,但对Z枣产生生物活性天然产物的分子机制仍然知之甚少。此外,被鉴定为负责合成这些化合物的潜在差异表达基因(DEGs)应进一步进行功能验证。人们注意到,总黄酮的含量,总酚,维生素C在成熟过程中显著增加,可溶性糖和有机酸含量逐渐下降。在这次审查中,我们还仔细研究了阻碍枣果资源利用的挑战,并提出了进一步研究的潜在领域。因此,我们的评论为未来开发基于枣的营养化合物以及将其营养元素纳入功能食品行业提供了宝贵的资源。
    The fruit of the jujube tree is high in nutrients and has various health benefits. China is a major producer of jujube, and it is now cultivated all around the world. Numerous studies have demonstrated the nutritional value and potential health advantages of bioactive compounds found in the jujube tree. Furthermore, the jujube tree has a remarkable 7000-year agricultural history. The jujube plant has developed a rich gene pool, making it a valuable resource for germplasm. Different studies have focused on the developmental stages of jujube fruits to identify the optimal time for harvest and to assess the changes in their bioactive natural compounds or products during the process of development but the molecular mechanism underlying the production of bioactive natural products in Z. jujuba is still poorly understood. Moreover, the potential differential expressed genes (DEGs) identified as responsible for the synthesis of these compounds should be further functionally verified. It has been noticed that the contents of total flavonoids, total phenolic, and vitamin C increase significantly during the ripening process, while the contents of soluble sugars and organic acids decrease gradually. In this review, we have also scrutinized the challenges that hinder the utilization of jujube fruit resources and suggested potential areas for further research. As such, our review serves as a valuable resource for the future development of jujube-based nutritional compounds and the incorporation of their nutritional elements into the functional foods industry.
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  • 文章类型: Journal Article
    阿拉伯木聚糖(AXs)是天然存在于谷物中的具有复杂结构的非淀粉多糖(即,大麦,玉米,和其他),提供许多健康益处,尤其是作为益生元。AXs可根据其溶解度分为水可萃取(WEAX)和水不可萃取(WUAX)。其性质受谷物来源和提取方法的影响。大量研究表明,AXs发挥重要的健康影响,包括葡萄糖和脂质代谢调节和免疫系统增强,这是由AXs和肠道微生物群之间的相互作用诱导的。最近的研究强调了AX生理效应对结构的依赖性,倡导对结构-活动关系有更深入的理解。虽然关于WEAX的系统研究很普遍,关于WUAX的知识差距仍然存在,尽管谷物丰度较高。因此,这篇评论报告了WUAX结构性质的最新数据(化学结构,分支,和MW)在不同处理下的谷物中。它讨论了WUAX在烘焙中的应用以及肠道发酵的好处。
    Arabinoxylans (AXs) are non-starch polysaccharides with complex structures naturally occurring in grains (i.e., barley, corn, and others), providing many health benefits, especially as prebiotics. AXs can be classified as water-extractable (WEAX) and water-unextractable (WUAX) based on their solubility, with properties influenced by grain sources and extraction methods. Numerous studies show that AXs exert an important health impact, including glucose and lipid metabolism regulation and immune system enhancement, which is induced by the interactions between AXs and the gut microbiota. Recent research underscores the dependence of AX physiological effects on structure, advocating for a deeper understanding of structure-activity relationships. While systematic studies on WEAX are prevalent, knowledge gaps persist regarding WUAX, despite its higher grain abundance. Thus, this review reports recent data on WUAX structural properties (chemical structure, branching, and MW) in cereals under different treatments. It discusses WUAX applications in baking and the benefits deriving from gut fermentation.
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  • 文章类型: Journal Article
    乳脂肪球膜(MFGM)是包裹天然乳脂肪球(MFGs)的三层膜状结构。MFGM由于其组成蛋白质的许多生理功能而有望作为营养补充剂。这篇综述总结并比较了不同物种之间MFGM蛋白组成的差异,包括牛,山羊,骆驼,马雷斯,还有驴,和不同的哺乳期,如初乳和成熟牛奶,通过蛋白质组学和质谱等技术评估。我们还讨论了MFGM蛋白质在整个生命中的健康益处。MFGM蛋白促进肠道发育,神经发育,通过上调紧密连接蛋白表达来促进葡萄糖和脂质代谢,大脑功能相关基因,以及葡萄糖和脂肪酸的生物合成过程。我们专注于MFGM蛋白的这些有益作用的潜在机制。MFGM蛋白激活信号通路中的关键物质,如磷脂酰肌醇3-激酶/蛋白激酶B,丝裂原活化蛋白激酶,和肌球蛋白轻链激酶信号通路。总的来说,MFGM蛋白的消费在赋予健康益处方面起着至关重要的作用,其中一些在整个哺乳动物生命周期中都很重要。
    哺乳动物中MFGM蛋白的类型和数量,通过蛋白质组学和质谱分析评估,是总结的。初乳MFGM含有更多的急性期蛋白,而成熟的牛奶有更高水平的粘蛋白(1和15),ADPH,XDH,和FABP。MFGM蛋白的健康益处,包括肠道发育,神经发育,和增强免疫活性,是总结的。MFGM蛋白已被证明显著激活PI3K/Akt/mTOR信号通路,促进细胞增殖和糖脂代谢。
    Milk fat globule membrane (MFGM) is a three-layer membrane-like structure encasing natural milk fat globules (MFGs). MFGM holds promise as a nutritional supplement because of the numerous physiological functions of its constituent protein. This review summarizes and compares the differences in MFGM protein composition across various species, including bovines, goats, camels, mares, and donkeys, and different lactation periods, such as colostrum and mature milk, as assessed by techniques such as proteomics and mass spectrometry. We also discuss the health benefits of MFGM proteins throughout life. MFGM proteins promote intestinal development, neurodevelopment, and glucose and lipid metabolism by upregulating tight junction protein expression, brain function-related genes, and glucose and fatty acid biosynthesis processes. We focus on the mechanisms underlying these beneficial effects of MFGM proteins. MFGM proteins activate key substances in in signaling pathways, such as the phosphatidylinositol 3-kinase/protein kinase B, mitogen-activated protein kinase, and myosin light chain kinase signaling pathways. Overall, the consumption of MFGM proteins plays an essential role in conferring health benefits, some of which are important throughout the mammalian life cycle.
    Types and amounts of MFGM proteins in mammals, as assessed by proteomic and mass spectrometry analysis, are summarized.Colostrum MFGM contains more acute phase proteins, whereas mature milk has higher levels of mucins (1 and 15), ADPH, XDH, and FABP.Health benefits of MFGM proteins, including intestinal development, neurodevelopment, and immune activity enhancement, are summarized.MFGM proteins have been shown to significantly activate the PI3K/Akt/mTOR signaling pathway, promoting cell proliferation and glycolipid metabolism.
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