■本研究旨在比较常规脱落细胞学(EC)和离心液基细胞学(CLBC)在对照中的疗效,白斑,和口腔鳞状细胞癌(OSCC)患者。口腔白斑和口腔癌需要早期明确诊断以获得更好的预后结果。口服EC,一种微创技术,包括检查组织表面脱落的细胞,用作早期诊断方法。CLBC是一种改进的技术,用于提高细胞学检查结果的质量。
■对30名受试者进行了比较研究,其中,对照组10例,10口腔白斑,10例OSCC根据适当的纳入和排除标准选择这些受试者。每组病例行常规和CLBC。在这些组之间就细胞和背景基质因子进行比较。收集样品的适当定性评价并使用卡方检验进行统计分析。值的显著性水平为P<0.05。
■对于某些参数,例如细胞重叠清晰背景,获得了显着结果,控制中的均匀分布,白斑,和OSCC,P=0.004**,P=0.001**,P=0.006**使用CLBC。
■与常规细胞学相比,CLBC更好,视野更清晰,可用于早期诊断。
UNASSIGNED: This study aims to compare the efficacy between conventional exfoliative cytology (EC) and centrifuged liquid-based cytology (CLBC) in control,
leukoplakia, and oral squamous cell carcinoma (OSCC) patients. Oral
leukoplakia and oral cancer require an early definitive diagnosis for better prognostic outcome. Oral EC, a minimally invasive technique that involves the examination of desquamated cells from the tissue surfaces used as a method of early diagnosis. CLBC is a modified technique that is used to achieve improved quality of the cytology findings.
UNASSIGNED: A comparative study was done in 30 subjects, of which, 10 cases from control group, 10 oral
leukoplakia, and 10 OSCC cases. These subjects were selected according to the appropriate inclusion and exclusion criteria. The cases in each group underwent conventional as well as CLBC. The comparison was carried out between these groups with respect to the cellular and background stromal factors. Appropriate qualitative evaluation of the samples was collected and statistical analysis was done using the Chi-squared test. The significance level of value was P < 0.05.
UNASSIGNED: Significant results were obtained for certain parameters such as cellular overlap clear background, uniform distribution in control,
leukoplakia, and OSCC with a P = 0.004**, P = 0.001**, P = 0.006** using CLBC.
UNASSIGNED: CLBC is better and give clearer vision as compared to conventional cytology and can be used in the early diagnosis.