PDF(Pubmed)
Abstract：
The serum levels of iron, zinc and copper in patients with leukoplakia, oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC) and compare them with normal subjects is of interest to dentists. The effort was to determine a parameter that will aid the initial diagnosis, a more efficient therapy plan, and ultimately a better prognosis. Participants in the study comprised 40 healthy normal volunteers, 60 patients diagnosed with leukoplakia, 60 patients diagnosed with OSCC, and 60 patients diagnosed with OSMF. After fasting for the whole night, blood samples were taken from each participant. There was analysis by inductively coupled plasma-optical emission spectrometry (ICP-OES) for the determination of trace elements; iron, copper, and zinc. The serum levels of iron and zinc in normal subjects was greater as compared to patients with leukoplakia, OSMF and OSCC. There was increase in serum copper levels in patients with oral leukoplakia, OSMF and OSCC as compared with normal subjects.
摘要：
血清铁水平,白斑患者的锌和铜，口腔粘膜下纤维化（OSMF）和口腔鳞状细胞癌（OSCC），并将它们与正常受试者进行比较是牙医感兴趣的。努力是确定一个有助于初步诊断的参数，更有效的治疗方案,最终更好的预后。这项研究的参与者包括40名健康的正常志愿者，60例诊断为白斑，60例确诊为OSCC，60例患者诊断为OSMF。在整个晚上禁食之后，从每位参与者身上采集血液样本.通过电感耦合等离子体发射光谱法(ICP-OES)分析测定微量元素；铁，铜，和锌。与白斑患者相比，正常人的血清铁和锌水平更高，OSMF和OSCC。口腔白斑患者血清铜水平升高，与正常受试者相比,OSMF和OSCC。
