Surgical approaches

手术入路
  • 文章类型: Journal Article
    目的:在比较咽后淋巴结(RPLN)转移的各种手术方法时,关于功能结局和并发症的知识存在差距。
    目的:探讨围手术期结局,功能结果,和治疗RPLN转移相关的并发症。
    方法:使用系统评价和Meta分析扩展范围评价的首选报告项目(PRISMA-ScR)方案对PubMed和Scopus数据库进行范围审查。
    方法:我们从开始到2023年1月系统地检索了2个数据库中的文章,以检查咽后腔的治疗方法和术后结果。我们包括了关于手术方法的英文记录,并发症,>18岁咽后淋巴结肿大患者的功能结局。
    结果:确定了一百九十九篇文章,其中17人被纳入分析。三项研究评估了辐射后环境中的RPLN解剖。我们发现咽后淋巴结病手术后的功能结果和并发症的知识有限。总的来说,35/170例患者(20.5%)有急性术后吞咽困难.然而,吞咽困难的评估是有限的,在大多数研究中没有描述。术后神经病变和血肿的总发生率分别为4.1%和4.7%,分别。经颈入路无术后血肿记录。
    结论:我们的发现强调需要进一步研究RPLN剥离术后的结果。我们建议进一步研究,重点是客观的吞咽评估和两种手术方法的长期结果。
    OBJECTIVE: A gap in knowledge exists concerning the functional outcomes and complications when comparing various surgical approaches for retropharyngeal lymph node (RPLN) metastases.
    OBJECTIVE: To explore perioperative outcomes, functional outcomes, and complications associated in the treatment of RPLN metastases.
    METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) protocol was used to conduct a scoping review of the PubMed and Scopus databases.
    METHODS: We systematically searched 2 databases from inception to January 2023 for articles examining the treatment approaches and postoperative outcomes in the retropharyngeal space. We included English records about surgical approaches, complications, functional outcomes for patients >18 years old with retropharyngeal lymphadenopathy.
    RESULTS: One-hundred ninety-nine articles were identified, of which 17 were included in the analysis. Three studies assessed RPLN dissection in the postradiation setting. We identified limited knowledge about functional outcomes and complications following surgery for retropharyngeal lymphadenopathy. Overall, acute postoperative dysphagia was documented in 35/170 patients (20.5%). However, the assessment of dysphagia was limited, and not described in the majority of studies. The overall rate of postoperative neuropathy and hematoma were 4.1% and 4.7%, respectively. No postoperative hematomas were documented in the transcervical approach.
    CONCLUSIONS: Our findings underscore the need for further research on postoperative outcomes following RPLN dissection. We recommend further studies focusing on objective swallow assessments and long-term outcomes of either surgical approaches.
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  • 文章类型: Case Reports
    当膈缺损允许腹部内容物进入胸腔时,就会出现前膈疝。它们可能是先天性的或获得性的;当获得时,典型的病因是外伤。如果没有治疗,他们有被监禁或勒死的危险.在筛查性胸部CT(计算机断层扫描)扫描中,偶然发现一名55岁的男性在胸骨切开术治疗心脏病时曾有剑突切除术史。在门诊手术咨询后不久,他出现了胃梗阻。他被送进了医院,进一步检查发现右侧4型膈疝伴有结肠嵌顿,胃窦,和幽门.进行鼻胃减压,其次是机器人辅助经腹腹膜前(r-TAPP)修复与网状物。他康复了,没有并发症。目前在文献中没有关于剑突切除术继发的前膈疝的报道。此病例证明了r-TAPP在这种罕见的膈前疝中的成功使用。
    Anterior diaphragmatic hernias manifest when a diaphragmatic defect permits abdominal contents to enter the thoracic cavity. They may be congenital or acquired; when acquired, the typical etiology is traumatic injury. Without treatment, they risk incarceration or strangulation. A 55-year-old male with a history of xiphoidectomy during sternotomy for cardiac disease was incidentally found to have an anterior diaphragmatic hernia on a screening chest CT (computed tomography) scan. He developed gastric obstruction shortly after an outpatient surgical consultation. He was admitted to the hospital, and further workup revealed a right-sided type-4 diaphragmatic hernia with an incarcerated colon, antrum, and pylorus. Nasogastric decompression was performed, followed by robotic-assisted transabdominal preperitoneal (r-TAPP) repair with mesh. He recovered without complications. There are currently no reports in the literature of an anterior diaphragmatic hernia secondary to a xiphoidectomy. This case demonstrates the successful use of r-TAPP for this rare presentation of an anterior diaphragmatic hernia.
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  • 文章类型: Journal Article
    背景/目标:胆脂瘤在耳鼻咽喉科中提出了重大的治疗挑战。这项研究旨在描述人口统计学和临床特征的影响,术前成像,和手术方法对胆脂瘤治疗的成功。方法:2021年1月至2022年12月在大学医院耳鼻喉科进行了横断面分析研究。它包括68例诊断为胆脂瘤的患者,重点关注三个目标:评估人口统计学和临床特征对治疗结果的影响,评估术前影像学检查结果的预测价值,并分析了手术因素的影响。结果:研究人群主要由男性(56%)和沙特(81%)患者组成,平均年龄为45岁。Logistic回归显示年龄较大(OR:1.05),男性(OR:0.63),和非沙特阿拉伯种族(OR:2.14)显着影响治疗结果。诸如严重疾病严重程度(OR:3.00)和较长症状持续时间(OR:0.96)的临床特征也影响治疗成功。在术前成像中,迷路瘘(回归系数:0.63)和硬膜外延伸(系数:0.55)是关键预测因子。显著影响结果的手术因素包括手术程度(完全切除OR:3.32)和内窥镜入路的使用(OR:1.42)。结论:这项研究强调了患者的人口统计学,临床资料,特定的术前影像学特征,和多因素的手术策略决定了胆脂瘤治疗的成功。这些发现表明,在胆脂瘤管理中需要一种量身定制的方法,加强基于综合术前评估的个体化治疗计划的重要性。
    Background/Objectives: Cholesteatoma presents significant management challenges in otolaryngology. This study aimed to delineate the influence of demographic and clinical characteristics, preoperative imaging, and surgical approaches on treatment success in cholesteatoma management. Methods: A cross-sectional analytical study was conducted at the Otolaryngology Department of the University Hospital from January 2021 to December 2022. It included 68 patients diagnosed with cholesteatoma, focusing on three objectives: assessing the impact of demographic and clinical characteristics on treatment outcomes, evaluating the predictive value of preoperative imaging findings, and analyzing the influence of surgical factors. Results: The study population predominantly consisted of male (56%) and Saudi (81%) patients, with an average age of 45 years. Logistic regression revealed that older age (OR: 1.05), male gender (OR: 0.63), and non-Saudi Arab ethnicity (OR: 2.14) significantly impacted treatment outcomes. Clinical characteristics such as severe disease severity (OR: 3.00) and longer symptom duration (OR: 0.96) also influenced treatment success. In preoperative imaging, labyrinthine fistula (Regression Coefficient: 0.63) and epidural extension (Coefficient: 0.55) emerged as key predictors. The surgical factors that significantly affected the outcomes included the extent of surgery (Complete Removal OR: 3.32) and the use of endoscopic approaches (OR: 1.42). Conclusions: This study highlights that patient demographics, clinical profiles, specific preoperative imaging features, and surgical strategies multifactorially determine cholesteatoma treatment success. These findings suggest the necessity for a tailored approach in cholesteatoma management, reinforcing the importance of individualized treatment plans based on comprehensive preoperative assessments.
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  • 文章类型: Journal Article
    CT交界处的结核(TB)并不常见(占所有脊柱TB的5%),鉴于其位置较深,胸骨在前面,肩胛骨在后面,因此难以手术接近。我们介绍了7例连续治疗的颈胸结核的治疗结果,并讨论了选择手术方法的理由。
    本研究包括7例新诊断的CT交界结核病例。普通射线照片,所有病例均进行CT/MRI上包括胸骨的CT脊柱矢状重建。确定了远端健康椎骨下方的椎间盘空间,并绘制了一条平行于椎间盘空间的线。如果这条线越过胸骨上切迹,推断该VB可以通过颈椎前路进入。如果疾病焦点在胸骨上切口水平或以下,增加了手动切开术/胸骨切开术,以更好地观察病变。
    所有7例病例均为女性,平均年龄20岁(9-45岁)。椎体病变累及2VB(n=3),3VB(n=2)和>3VB(n=2)。平均胸椎后凸为15°(范围10-25°)。7例均行前路减压手术,后凸畸形矫正和仪器稳定。前颈入路和手动切开/胸骨切开术各3例。在两个全脊椎病例中,我们进行了360°手术。6例患者在手术后3周内首次出现神经恢复迹象,随访3个月时神经基本恢复,1例部分恢复。12个月后,一旦在对比MRI上显示出治愈阶段,就停止ATT。
    CT交界处TB通常表现为严重的后凸畸形/神经缺陷。这些病例需要前路减压/全身切除术,畸形矫正,用颈椎前板进行间隙移植和器械稳定。全椎病变360°稳定。这些病变可以通过下颈椎前入路减压,有/无手术切开术。Karikari方法可用于确定是否需要切开切开以减压病变。
    UNASSIGNED: Tuberculosis (TB) of CT junction is uncommon (5 % of all spinal TB), and difficult to approach surgically in view of its deep location with sternum in front and scapula in the back. We present 7 consecutively treated cases of cervico-thoraccic TB for outcome of treatment and discuss rationale of choosing surgical approach.
    UNASSIGNED: Present study includes 7 freshly diagnosed cases of CT junction TB. Plain radiographs, sagittal reconstruction of CT spine that included sternum on CT/MRI was performed in all cases. Disc space below the distal healthy vertebrae was identified and a line parallel to disc space was drawn. If this line passes above suprasternal notch, it was inferred that this VB can be accessed by anterior cervical approach. If disease focus was at or below suprasternal notch level, manubriotomy/sternotomy was added for better visualization of the lesion.
    UNASSIGNED: All seven cases were female, with mean age of 20 years (9-45 years). The vertebral lesion involved 2VB (n = 3), 3VB (n = 2) and >3 VB (n = 2). The average Cervico-thoracic kyphosis was 15° (range 10-25°). All 7 cases were operated for anterior decompression, kyphotic deformity correction and instrumented stabilization. Anterior cervical approach and manubriotomy/sternotomy approach was performed in three cases each. In two pan-vertebral cases we performed 360° procedure. Six cases have shown first sign of neural recovery within 3 weeks of surgery and almost complete neural recovery at 3 months follow-up while one case showed partial recovery. ATT was stopped after 12 months once healed stage was demonstrated on contrast MRI in all.
    UNASSIGNED: CT junction TB usually presents with severe kyphotic deformity/neural deficit. These cases require anterior decompression/corpectomy, deformity correction, gap grafting and instrumented stabilization with anterior cervical plate. Lesion with pan-vertebral disease is stabilized 360°. These lesions can be decompressed by lower anterior cervical approach with/without manubriotomy. The Karikari method was useful in deciding the need for manubriotomy to decompress the lesion.
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  • 文章类型: Journal Article
    背景:鼻整理术的一个重要方面是通过进行背侧扩大(DA)鼻整理术来增强鼻背轮廓。随着对美学鼻改良的需求的增长,DA可以使用多种技术。这篇综述旨在对目前用于DA隆鼻的技术进行全面概述。
    方法:通过全面的文献检索确定了关于DA隆鼻技术的研究文章。Scopus,PubMed,和WebofScience被用作电子数据库。每个数据库都搜索了自成立以来发表的文章。本文献综述对DA隆鼻技术进行了研究。对所选研究的方法学质量进行了评估,并提取数据以检查所使用的材料,手术方法,并报告了每种技术的结果。各种DA方法,包括自体移植和合成植入物,在这篇综述中进行了深入的研究。比较方法可以帮助更好地理解它们各自的优点和局限性。
    结论:DA隆鼻技术丰富,每个人都有优势。患者鼻腔解剖,期望的结果,和潜在的风险必须由外科医生在确定他们的手术方法时考虑。DA方法继续快速发展,创造了对当前景观的透彻了解以做出明智的决定的需要。
    BACKGROUND: An essential aspect of rhinoplasty is the enhancement of the nasal dorsal contour by performing dorsal augmentation (DA) rhinoplasty. A wide range of techniques are available for DA as the demand for aesthetic nasal refinement grows. This review aims to provide a comprehensive overview of the current techniques used in DA rhinoplasty.
    METHODS: Research articles on DA rhinoplasty techniques were identified through a comprehensive literature search. Scopus, PubMed, and Web of Science were used as electronic databases. Each database was searched for articles published since its inception. DA rhinoplasty techniques were examined in this literature review. Methodological quality was assessed for the selected studies, and data was extracted to examine materials used, surgical approaches, and reported outcomes for each technique. Various DA methods, including autologous grafts and synthetic implants, are examined in-depth in this review. Comparing approaches can help better understand their respective advantages and limitations.
    CONCLUSIONS: A wealth of techniques is available for DA rhinoplasty, each with advantages. Patients\' nasal anatomy, desired outcomes, and potential risks must be considered by surgeons when determining their surgical approach. DA methods continue to evolve rapidly, creating a need for a thorough understanding of the current landscape to make informed decisions.
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  • 文章类型: Journal Article
    Comparison of gap arthroplasty (GAP), interpositional arthroplasty (IAP) and distraction osteogenesis (DO) simultaneous with interpositional arthroplasty (DO+IAP) in management of TMJ ankylosis is of interest to dentists. The study comprised 36 individuals with TMJ ankylosis, 16 of whom were female and 20 of whom were male. Both prior to and following surgery, the maximum inter-incisal opening (MIO) and facial pattern were noted. The postoperative MIO was 33.23 ± 1.23mm, 35.24 ± 1.11mm and 38.24 ± 1.34mm in GAP, IAP and DO+IAP respectively. Data is statistically significant with high MIO observed in DO+ IAP technique and low MIO in GAP technique (p < 0.005). In addition to lengthening the mandible, concurrently processed interpositional arthroplasty alongside DO for TMJ ankylosis corrects gross asymmetry of the face, occlusal mal-alignment, midline change, and creates room for previously un-erupted teeth to emerge.
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  • 文章类型: Journal Article
    腰椎融合术是各种脊柱疾病的公认治疗方法。然而,它的并发症之一,假关节炎,引起了极大的关注。本研究旨在探讨发病率,在10年时间内接受腰椎融合术的患者中,导致假关节炎的时间和预测因素.
    本研究的数据来自PearlDiver数据库,在该数据库中,对2010年1月1日至2022年10月31日期间接受多层腰椎融合术的患者的保险索赔进行了检查,以确定其索引程序的10年内假性关节病的索赔。各种各样的人口,共病,和手术因素进行了评估,包括年龄,性别,Elixhauser合并症指数(ECI),手术方法,物质使用障碍和脊柱疾病史。统计分析,包括卡方检验,多变量分析,和cox生存分析用于确定显著关联。
    在这项回顾性研究中纳入的76,337名患者中,在10年的随访中,平均7.38年,2.70%的患者被诊断为症状性腰椎假性关节炎。多变量和Cox风险分析显示,多水平原发性腰椎融合术后症状性假性关节炎发展的重要预测因素包括维生素D缺乏,骨关节炎,阿片类药物和NSAID的使用,烟草使用,和先天性脊柱疾病的既往史。
    总之,这项研究显示,在索引程序的10年内,有症状的腰椎假性关节病的发生率为2.70%。它强调了几个潜在的预测因素,包括合并症,手术方法,和物质使用障碍,与症状性假性关节炎的发展有关。未来的研究应该集中在完善我们对这些因素的理解上,以改善患者的预后并优化医疗资源分配。
    UNASSIGNED: Lumbar spinal fusion surgery is a well-established treatment for various spinal disorders. However, one of its complications, pseudoarthrosis, poses a significant concern. This study aims to explore the incidence, time and predictive factors contributing to pseudoarthrosis in patients who have undergone lumbar fusion surgery over a 10-year period.
    UNASSIGNED: Data for this research was sourced from the PearlDiver database where insurance claims of patients who underwent multilevel lumbar spinal fusion between 01/01/2010 and 10/31/2022 were examined for claims of pseudoarthrosis within the 10 years of their index procedure. A variety of demographic, comorbid, and surgical factors were assessed, including age, gender, Elixhauser Comorbidity Index (ECI), surgical approach, substance use disorders and history of spinal disorders. Statistical analyses, including chi-squared tests, multivariate analysis, and cox survival analysis were employed to determine significant associations.
    UNASSIGNED: Among the 76,337 patients included in this retrospective study, 2.70% were diagnosed with symptomatic lumbar pseudoarthrosis at an average of 7.38 years in a 10-year follow-up. Multivariate and Cox hazard analyses revealed that significant predictors of symptomatic pseudoarthrosis development following multilevel primary lumbar fusion include vitamin D deficiency, osteoarthritis, opioid and NSAID use, tobacco use, and a prior history of congenital spine disorders.
    UNASSIGNED: In summary, this study revealed a 2.70% incidence of symptomatic lumbar pseudoarthrosis within 10 years of the index procedure. It highlighted several potential predictive factors, including comorbidities, surgical approaches, and substance use disorders, associated with the development of symptomatic pseudoarthrosis. Future research should focus on refining our understanding of these factors to improve patient outcomes and optimize healthcare resource allocation.
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  • 文章类型: Case Reports
    该研究反映了一名69岁的女性患者,该患者有心肺疾病史,被诊断患有斑块状脑膜瘤。她的临床治疗需要手术切除肿瘤,随后是复杂的术后过程,包括心肺骤停和呼吸衰竭。组织学上,颅外脑膜瘤根据主要的细胞形态分为五种亚型,在这种情况下,脑膜上皮型很普遍。该报告还检查了完全切除肿瘤的意义,注意到总体全切除的复发率较低。此外,它讨论了随着年龄的增长和女性发病率的增加,颅外脑膜瘤的易感性增加。来自各种研究的数据强调了手术方法和切除程度在预测复发风险方面的重要性。病例报告最后强调了脑膜瘤病理的关键方面和确保患者康复的手术策略。这个病例的发现有助于更广泛地了解颅外脑膜瘤,他们的诊断,和管理。
    The study reflects on a 69-year-old female patient with a history of cardio-respiratory disorders who was diagnosed with meningioma en plaque. Her clinical management entailed surgical resection of the tumor, which was followed by a complex postoperative course, including cardiorespiratory arrest and respiratory failure. Histologically, extracranial meningiomas are categorized into five subtypes based on predominant cellular morphology, with the meningothelial type being prevalent in this case. The report also examines the significance of complete tumor resection, noting a lower recurrence rate with gross total resection. Additionally, it discusses the increased susceptibility of extracranial meningiomas with advancing age and a higher incidence in females. Data from various studies underscore the importance of a surgical approach and extent of resection in predicting recurrence risk. The case report concludes by highlighting the critical aspects of the pathology of meningiomas and the surgical strategy that ensured the patient\'s recovery. The findings from this case contribute to the broader understanding of extracranial meningiomas, their diagnosis, and management.
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  • 文章类型: Journal Article
    目的:手术治疗中脑毛细胞星形细胞瘤(PA)仍然是一个巨大的挑战。为了促进决策并在中脑PA患者的管理中获得更好的结果,作者提出了一种新的中脑PAs的放射学分类,并进行了长期随访。
    方法:57例于北京天坛医院接受手术治疗的中脑PA患者,首都医科大学,从2008年1月到2021年6月,进行了审查。根据MRI上确定的肿瘤位置和拓扑解剖变化,中脑PAs分为四种类型:硬(12/57,21.1%),tegmental(25/57,43.9%),导水管(5/57,8.8%),和tectal(15/57,26.3%)PA。相关的临床,放射学,收集和分析病理数据;手术程序和结果;以及长期结局.
    结果:1-,3-,5年生存率达到98%,96%,96%,分别,66.7%的病例实现了全切除,随后在17.5%的病例中几乎全部切除。临床和放射学特征,手术方法的选择,每种类型之间的长期术后缺陷不同。农村PA与年轻年龄相关(中位数为9岁,IQR5.0-12.8年);最大的肿瘤体积(中位数31.9cm3,IQR17.2-42.6cm3);术前最低的Karnofsky性能量表(KPS)评分(中位数65,IQR50-70);术前最常见的运动缺陷(91.7%);混合的固体-囊性成分(75%);占据脚入池;丘脑抬高和前室(内侧和/或外侧移位);uncus,和前连合;最多样化的手术入路;更频繁地使用多模式图像引导手术(58.3%);并且在长期随访中KPS评分的改善最显着。TegmentalPA与青少年和年轻人相关(中位年龄21岁,IQR8-33年);肿瘤体积(中位数13.9cm3,IQR9.5-20.5cm3);良好的术前KPS评分(中位数80,IQR70-80);混合的实囊成分(72%);占用环境水箱和小脑中脑裂;与背桥关系密切,小脑上花梗,和后下第三脑室;永久性术后感觉障碍的可能性更高(40%)。导水管和顶管PAs与小肿瘤体积相关(分别为中位数9.14cm3,IQR5.1-17.4cm3和中位数11.84cm3,IQR5.7-18.3cm3),脑积水的比例更高(80%和86.7%,分别),和简单选择有限的手术方法。
    结论:建立了中脑PAs的新颖而全面的放射学分类,这将成为患者管理的宝贵工具,并促进不同研究和出版物之间的统一沟通和比较。
    OBJECTIVE: Surgery for midbrain pilocytic astrocytoma (PA) remains a formidable challenge. To facilitate decision-making and achieve a better outcome in the management of patients with midbrain PA, the authors have proposed a novel radiological classification of midbrain PAs with long-term follow-up.
    METHODS: Fifty-seven midbrain PA patients who underwent surgery at Beijing Tiantan Hospital, Capital Medical University, from January 2008 to June 2021, were reviewed. Based on tumor location and the topological anatomical change identified on MRI, midbrain PAs were categorized into four types: crural (12/57, 21.1%), tegmental (25/57, 43.9%), aqueductal (5/57, 8.8%), and tectal (15/57, 26.3%) PAs. The relevant clinical, radiological, and pathological data; surgical procedures and results; and long-term outcomes were collected and analyzed.
    RESULTS: The 1-, 3-, and 5-year survival rates reached 98%, 96%, and 96%, respectively, with gross-total resection achieved in 66.7% of cases, followed by near-total resection in 17.5% cases. The clinical and radiological features, selection of surgical approaches, and long-term postoperative deficits were distinct among each type. Crural PAs were associated with younger age (median 9 years, IQR 5.0-12.8 years); the largest tumor volume (median 31.9 cm3, IQR 17.2-42.6 cm3); the lowest preoperative Karnofsky Performance Scale (KPS) score (median 65, IQR 50-70); the most frequent preoperative motor deficit (91.7%); a mixed solid-cystic component (75%); occupation of the crural cistern; elevation and rotation of the thalamus (medial and/or lateral); displacement of the anterior third ventricle, uncus, and anterior commissure; the most diverse surgical approaches; more frequent use of multimodality image-guided surgery (58.3%); and the most remarkable improvement in KPS score at long-term follow-up. Tegmental PAs were associated with adolescents and young adults (median age 21 years, IQR 8-33 years); tumor volume (median 13.9 cm3, IQR 9.5-20.5 cm3); a good preoperative KPS score (median 80, IQR 70-80); a mixed solid-cystic component (72%); occupation of the ambient cistern and cerebellomesencephalic fissure; a close relationship with the dorsal pons, superior cerebellar peduncle, and posterior inferior third ventricle; and a higher probability of permanent postoperative sensory deficits (40%). Aqueductal and tectal PAs were associated with small tumor volume (median 9.14 cm3, IQR 5.1-17.4 cm3 and median 11.84 cm3, IQR 5.7-18.3 cm3, respectively), a higher percentage of hydrocephalus (80% and 86.7%, respectively), and a straightforward selection of limited surgical approaches.
    CONCLUSIONS: A novel and comprehensive radiological classification of midbrain PAs was established, which will serve as a valuable tool in patient management and promote uniform communication and comparison across different studies and publications.
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  • 文章类型: Meta-Analysis
    该网络荟萃分析评估了七种内窥镜检查方法的结果,为研究人员和从业人员选择甲状腺癌患者的最佳方法提供有价值的见解。
    在PubMed上进行了系统的文献检索,截至2023年3月的Embase和WebofScience数据库。分析包括七个内窥镜入路,通过网络荟萃分析关注他们各自的结果。
    这项荟萃分析包括44项研究,涉及8,672名患者。与其他方法相比,腋下双侧乳腺入路(ABBA)和单侧腋下乳腺入路(UABA)在减少手术时间方面显示出优势(MD=19.66分钟,95%CI=-31.66至70.98;MD=30.32分钟,95%CI分别=-1.45至62.09)。UABA和前胸入路(ACA)在控制术中出血方面具有优势(MD=-3.37mL,95%CI=-22.58至15.85;MD=-13.77mL,95%CI分别=-28.851.31)。UABA和ACA在减少住院时间方面也显示出优势(MD=-0.39天,95%CI=-1.48至0.71;MD=-0.26天,95%CI分别=-1.33至0.81)。经口入路(OA)的结果与常规开放式甲状腺切除术(COT)的结果相当,并且在淋巴结取出和转移性淋巴结评估方面优于其他内窥镜手术。对于刺激的血清甲状腺球蛋白(TG)水平,与COT相比,双侧腋乳入路(BABA)和OA之间没有显着差异。然而,胸乳入路(CBA)显示明显低于COT(MD=-0.40ng/ml,95%CI=-0.72至-0.09)。无气单侧经腋下入路(GUA)组患者的美容满意度显着提高(MD=-2.08,95%CI=-3.35至-0.82)。重要的是,腔镜甲状腺切除术和COT手术并发症的发生率无显著差异。
    内镜甲状腺手术是甲状腺癌患者安全有效的选择。不同的方法有其优势,允许根据患者的需求进行个性化选择。ABBA和UABA的手术时间较短,而UABA和ACA擅长控制出血和缩短住院时间。OA显示出淋巴结评估的希望。这些发现有助于越来越多的证据支持内窥镜检查方法,扩大甲状腺癌患者的治疗选择。
    This network meta-analysis assesses the outcomes of seven endoscopic approaches, offering valuable insights for researchers and practitioners in choosing the best method for thyroid cancer patients.
    A systematic literature search was conducted in the PubMed, Embase and Web of Science databases up to March 2023. The analysis included seven endoscopic approaches, with a focus on their respective outcomes through network meta-analysis.
    This meta-analysis included 44 studies involving 8,672 patients. The axillo-bilateral breast approach (ABBA) and unilateral axillo-breast approach (UABA) showed advantages in terms of reduced operative time compared to other approaches (MD = 19.66 minutes, 95% CI = -31.66 to 70.98; MD = 30.32 minutes, 95% CI = -1.45 to 62.09, respectively). The UABA and anterior chest approach (ACA) exhibited superiority in controlling intraoperative bleeding (MD = -3.37 mL, 95% CI = -22.58 to 15.85; MD = -13.77 mL, 95% CI = -28.85 1.31, respectively). UABA and ACA also showed advantages in reducing hospital stays (MD = -0.39 days, 95% CI = -1.48 to 0.71; MD = -0.26 days, 95% CI = -1.33 to 0.81, respectively). The transoral approach (OA) yielded results comparable to those of conventional open thyroidectomy (COT) and outperformed other endoscopic surgeries with regards to lymph node retrieval and metastatic lymph node assessment. For the stimulated serum thyroglobulin (TG) levels, no significant difference was observed between bilateral axillo-breast approach (BABA) and OA compared to COT. However, chest-breast approach (CBA) showed significantly lower levels than COT (MD=-0.40 ng/ml, 95% CI =-0.72 to -0.09). Patients in the gasless unilateral transaxillary approach (GUA) group experienced a significant improvement in cosmetic satisfaction (MD=-2.08, 95% CI =-3.35 to -0.82). Importantly, no significant difference was observed in the incidence of surgical complications between endoscopic thyroidectomy and COT.
    Endoscopic thyroid surgery is a safe and effective choice for thyroid cancer patients. Different approaches have their advantages, allowing personalized selection based on the patient\'s needs. ABBA and UABA have shorter operative times, while UABA and ACA excel at controlling bleeding and shortening hospital stays. OA shows promise for lymph node assessment. These findings contribute to the growing evidence supporting endoscopic methods, expanding treatment options for thyroid cancer patients.
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