Surgical approaches

手术入路
  • 文章类型: Journal Article
    腿部长度差异(LLD)是全髋关节置换术(THA)后的常见并发症。THA的直接前路(DAA)由于其优点而越来越受欢迎,但对LLD的发病率和大小的研究有限。这篇系统的综述旨在探讨DAA和其他方法在LLD上的差异,以及在DAA中控制LLD的技术。
    进行了全面的文献检索,以确定通过DAA与其他手术方法比较THA的相关研究,并研究了控制DAA中LLD的方法,遵循PRISMA指南和PROSPERO的先验注册(CRD42023412644)。评估纳入研究的质量。对术前和术后LLD和其他相关结局的数据进行描述性提取和分析。
    总共,29项研究纳入本系统综述。大多数(86%)被归类为IV级证据。DAA与后入路(PA)或前外侧入路(ALA)之间的比较显示,与PA和ALA相比,DAA的LLD>10mm的发生率较低。评估了不同的术前和术中技术,但对于DAA中预防LLD的最佳方法尚未达成共识。
    与其他手术方法相比,DAA在预防LLD方面显示出相当或更好的结果。患者仰卧安置,直接测量腿,综合框架的使用有助于这些结果。带网格和术前计划的术中透视提供了一个很好的选择,特别是为了训练,但其在有经验的DAA外科医生预防LLD中的作用需要进一步研究.
    UNASSIGNED: Leg length discrepancy (LLD) is a common complication following total hip arthroplasty (THA). The direct anterior approach (DAA) for THA is gaining popularity due to its advantages, but there is limited research on the incidence and size of LLD. This systematic review aims to explore the differences in LLD between DAA and other approaches, as well as the techniques to control LLD in DAA.
    UNASSIGNED: A comprehensive literature search was conducted to identify relevant studies comparing THA by DAA with other surgical approaches and investigating methods to control LLD in DAA, following PRISMA guidelines and a priori registration on PROSPERO (CRD42023412644). The quality of the included studies was assessed. Data on preoperative and postoperative LLD and other relevant outcomes were extracted and analyzed descriptively.
    UNASSIGNED: In total, 29 studies were included in this systematic review. The majority (86%) were classified as level IV evidence. Comparisons between DAA and posterior approach (PA) or anterolateral approach (ALA) showed DAA had lower rates of LLD >10 mm compared to PA and ALA. Different pre- and intra-operative techniques were evaluated, but no consensus on the best method for preventing LLD in DAA was reached.
    UNASSIGNED: DAA shows comparable or superior results in the prevention of LLD compared to other surgical approaches. Supine patient placement, direct leg measurement, and the use of IF contribute to these outcomes. Intraoperative fluoroscopy with a grid and preoperative planning offers a good option, especially for training purposes, but its role in preventing LLD by experienced DAA surgeons needs further investigation.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:在比较咽后淋巴结(RPLN)转移的各种手术方法时,关于功能结局和并发症的知识存在差距。
    目的:探讨围手术期结局,功能结果,和治疗RPLN转移相关的并发症。
    方法:使用系统评价和Meta分析扩展范围评价的首选报告项目(PRISMA-ScR)方案对PubMed和Scopus数据库进行范围审查。
    方法:我们从开始到2023年1月系统地检索了2个数据库中的文章,以检查咽后腔的治疗方法和术后结果。我们包括了关于手术方法的英文记录,并发症,>18岁咽后淋巴结肿大患者的功能结局。
    结果:确定了一百九十九篇文章,其中17人被纳入分析。三项研究评估了辐射后环境中的RPLN解剖。我们发现咽后淋巴结病手术后的功能结果和并发症的知识有限。总的来说,35/170例患者(20.5%)有急性术后吞咽困难.然而,吞咽困难的评估是有限的,在大多数研究中没有描述。术后神经病变和血肿的总发生率分别为4.1%和4.7%,分别。经颈入路无术后血肿记录。
    结论:我们的发现强调需要进一步研究RPLN剥离术后的结果。我们建议进一步研究,重点是客观的吞咽评估和两种手术方法的长期结果。
    OBJECTIVE: A gap in knowledge exists concerning the functional outcomes and complications when comparing various surgical approaches for retropharyngeal lymph node (RPLN) metastases.
    OBJECTIVE: To explore perioperative outcomes, functional outcomes, and complications associated in the treatment of RPLN metastases.
    METHODS: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) protocol was used to conduct a scoping review of the PubMed and Scopus databases.
    METHODS: We systematically searched 2 databases from inception to January 2023 for articles examining the treatment approaches and postoperative outcomes in the retropharyngeal space. We included English records about surgical approaches, complications, functional outcomes for patients >18 years old with retropharyngeal lymphadenopathy.
    RESULTS: One-hundred ninety-nine articles were identified, of which 17 were included in the analysis. Three studies assessed RPLN dissection in the postradiation setting. We identified limited knowledge about functional outcomes and complications following surgery for retropharyngeal lymphadenopathy. Overall, acute postoperative dysphagia was documented in 35/170 patients (20.5%). However, the assessment of dysphagia was limited, and not described in the majority of studies. The overall rate of postoperative neuropathy and hematoma were 4.1% and 4.7%, respectively. No postoperative hematomas were documented in the transcervical approach.
    CONCLUSIONS: Our findings underscore the need for further research on postoperative outcomes following RPLN dissection. We recommend further studies focusing on objective swallow assessments and long-term outcomes of either surgical approaches.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:鼻整理术的一个重要方面是通过进行背侧扩大(DA)鼻整理术来增强鼻背轮廓。随着对美学鼻改良的需求的增长,DA可以使用多种技术。这篇综述旨在对目前用于DA隆鼻的技术进行全面概述。
    方法:通过全面的文献检索确定了关于DA隆鼻技术的研究文章。Scopus,PubMed,和WebofScience被用作电子数据库。每个数据库都搜索了自成立以来发表的文章。本文献综述对DA隆鼻技术进行了研究。对所选研究的方法学质量进行了评估,并提取数据以检查所使用的材料,手术方法,并报告了每种技术的结果。各种DA方法,包括自体移植和合成植入物,在这篇综述中进行了深入的研究。比较方法可以帮助更好地理解它们各自的优点和局限性。
    结论:DA隆鼻技术丰富,每个人都有优势。患者鼻腔解剖,期望的结果,和潜在的风险必须由外科医生在确定他们的手术方法时考虑。DA方法继续快速发展,创造了对当前景观的透彻了解以做出明智的决定的需要。
    BACKGROUND: An essential aspect of rhinoplasty is the enhancement of the nasal dorsal contour by performing dorsal augmentation (DA) rhinoplasty. A wide range of techniques are available for DA as the demand for aesthetic nasal refinement grows. This review aims to provide a comprehensive overview of the current techniques used in DA rhinoplasty.
    METHODS: Research articles on DA rhinoplasty techniques were identified through a comprehensive literature search. Scopus, PubMed, and Web of Science were used as electronic databases. Each database was searched for articles published since its inception. DA rhinoplasty techniques were examined in this literature review. Methodological quality was assessed for the selected studies, and data was extracted to examine materials used, surgical approaches, and reported outcomes for each technique. Various DA methods, including autologous grafts and synthetic implants, are examined in-depth in this review. Comparing approaches can help better understand their respective advantages and limitations.
    CONCLUSIONS: A wealth of techniques is available for DA rhinoplasty, each with advantages. Patients\' nasal anatomy, desired outcomes, and potential risks must be considered by surgeons when determining their surgical approach. DA methods continue to evolve rapidly, creating a need for a thorough understanding of the current landscape to make informed decisions.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Meta-Analysis
    该网络荟萃分析评估了七种内窥镜检查方法的结果,为研究人员和从业人员选择甲状腺癌患者的最佳方法提供有价值的见解。
    在PubMed上进行了系统的文献检索,截至2023年3月的Embase和WebofScience数据库。分析包括七个内窥镜入路,通过网络荟萃分析关注他们各自的结果。
    这项荟萃分析包括44项研究,涉及8,672名患者。与其他方法相比,腋下双侧乳腺入路(ABBA)和单侧腋下乳腺入路(UABA)在减少手术时间方面显示出优势(MD=19.66分钟,95%CI=-31.66至70.98;MD=30.32分钟,95%CI分别=-1.45至62.09)。UABA和前胸入路(ACA)在控制术中出血方面具有优势(MD=-3.37mL,95%CI=-22.58至15.85;MD=-13.77mL,95%CI分别=-28.851.31)。UABA和ACA在减少住院时间方面也显示出优势(MD=-0.39天,95%CI=-1.48至0.71;MD=-0.26天,95%CI分别=-1.33至0.81)。经口入路(OA)的结果与常规开放式甲状腺切除术(COT)的结果相当,并且在淋巴结取出和转移性淋巴结评估方面优于其他内窥镜手术。对于刺激的血清甲状腺球蛋白(TG)水平,与COT相比,双侧腋乳入路(BABA)和OA之间没有显着差异。然而,胸乳入路(CBA)显示明显低于COT(MD=-0.40ng/ml,95%CI=-0.72至-0.09)。无气单侧经腋下入路(GUA)组患者的美容满意度显着提高(MD=-2.08,95%CI=-3.35至-0.82)。重要的是,腔镜甲状腺切除术和COT手术并发症的发生率无显著差异。
    内镜甲状腺手术是甲状腺癌患者安全有效的选择。不同的方法有其优势,允许根据患者的需求进行个性化选择。ABBA和UABA的手术时间较短,而UABA和ACA擅长控制出血和缩短住院时间。OA显示出淋巴结评估的希望。这些发现有助于越来越多的证据支持内窥镜检查方法,扩大甲状腺癌患者的治疗选择。
    This network meta-analysis assesses the outcomes of seven endoscopic approaches, offering valuable insights for researchers and practitioners in choosing the best method for thyroid cancer patients.
    A systematic literature search was conducted in the PubMed, Embase and Web of Science databases up to March 2023. The analysis included seven endoscopic approaches, with a focus on their respective outcomes through network meta-analysis.
    This meta-analysis included 44 studies involving 8,672 patients. The axillo-bilateral breast approach (ABBA) and unilateral axillo-breast approach (UABA) showed advantages in terms of reduced operative time compared to other approaches (MD = 19.66 minutes, 95% CI = -31.66 to 70.98; MD = 30.32 minutes, 95% CI = -1.45 to 62.09, respectively). The UABA and anterior chest approach (ACA) exhibited superiority in controlling intraoperative bleeding (MD = -3.37 mL, 95% CI = -22.58 to 15.85; MD = -13.77 mL, 95% CI = -28.85 1.31, respectively). UABA and ACA also showed advantages in reducing hospital stays (MD = -0.39 days, 95% CI = -1.48 to 0.71; MD = -0.26 days, 95% CI = -1.33 to 0.81, respectively). The transoral approach (OA) yielded results comparable to those of conventional open thyroidectomy (COT) and outperformed other endoscopic surgeries with regards to lymph node retrieval and metastatic lymph node assessment. For the stimulated serum thyroglobulin (TG) levels, no significant difference was observed between bilateral axillo-breast approach (BABA) and OA compared to COT. However, chest-breast approach (CBA) showed significantly lower levels than COT (MD=-0.40 ng/ml, 95% CI =-0.72 to -0.09). Patients in the gasless unilateral transaxillary approach (GUA) group experienced a significant improvement in cosmetic satisfaction (MD=-2.08, 95% CI =-3.35 to -0.82). Importantly, no significant difference was observed in the incidence of surgical complications between endoscopic thyroidectomy and COT.
    Endoscopic thyroid surgery is a safe and effective choice for thyroid cancer patients. Different approaches have their advantages, allowing personalized selection based on the patient\'s needs. ABBA and UABA have shorter operative times, while UABA and ACA excel at controlling bleeding and shortening hospital stays. OA shows promise for lymph node assessment. These findings contribute to the growing evidence supporting endoscopic methods, expanding treatment options for thyroid cancer patients.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:蝶眶脑膜瘤(SOM)是罕见的肿瘤,起源于蝶骨和眶结构周围的脑膜。手术切除是SOM的主要治疗方法。几十年来,已经描述了几种手术方法,包括经颅显微外科手术(MTA),鼻内镜(EEAs),内镜经眶(ETOAs),和组合方法,手术方法的选择仍然是一个争论的话题。
    目的:本系统综述和荟萃分析旨在比较不同手术方式治疗SOM的临床和手术结果。讨论手术技术,结果,以及影响手术决策的因素。
    方法:对PubMed,OvidMEDLINE,直到2023年,OvidEMBASE都发表了关于手术治疗SOM的作用的文章。根据系统评价的首选报告项目和荟萃分析指南进行系统评价。进行荟萃分析以估计合并事件发生率并评估异质性。固定和随机效应用于评估出现症状的95%保密间隔(CI),结果,和并发症。
    结果:共有59项研究,包括1903例患者纳入系统评价和荟萃分析。总切除率(GTR)从ETOA的23.5%到MTA的59.8%不等。术后总复发率为20.7%。5年和10年的无进展生存率(PFS)分别为75.5%和49.1%,分别。视力和眼球突出改善率分别为57.5%和79.3%,分别。术后脑神经(CN)局灶性缺损占20.6%。总体脑脊液(CSF)泄漏率为3.9%,其他并发症发生在13.9%的病例中。MTA的GTR率最高(59.8%,95CI=49.5-70.2%;p=0.001),但与CN缺乏增加相关(21.0%,95CI=14.5-27.6%)。ETO的GTR率最低(23.5%,95CI=0.0-52.5%;p=0.001),而ETOA和EEA的组合具有最高的CSF泄漏率(20.3%,95CI=0.0-46.7%;p=0.551)。ETOAs与更好的突起改善相关(79.4%,95CI=57.3-100%;p=0.002),而解剖学一级病变与更好的视力相关(71.5%,95CI=63.7-79.4;p=0.003)和突起(60.1%,95CI=38.0-82.2;p=0.001)回收率。手术入路之间的PFS率没有显着差异。
    结论:SOM的手术治疗旨在保持视觉功能和改善眼球突出。不同的手术方法提供不同的GTR率,并发症,和功能结果。涉及颅底团队的多学科方法对于优化患者预后至关重要。
    BACKGROUND: Spheno-orbital meningiomas (SOMs) are rare tumors arising from the meninges surrounding the sphenoid bone and orbital structures. Surgical resection is the primary treatment approach for SOMs. Several surgical approaches have been described during the decades, including microsurgical transcranial (MTAs), endoscopic endonasal (EEAs), endoscopic transorbital (ETOAs), and combined approaches, and the choice of surgical approach remains a topic of debate.
    OBJECTIVE: This systematic review and meta-analysis aim to compare the clinical and surgical outcomes of different surgical approaches used for the treatment of SOMs, discussing surgical techniques, outcomes, and factors influencing surgical decision making.
    METHODS: A comprehensive literature review of the databases PubMed, Ovid MEDLINE, and Ovid EMBASE was conducted for articles published on the role of surgery for the treatment of SOMs until 2023. The systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Meta-analysis was performed to estimate pooled event rates and assess heterogeneity. Fixed- and random-effects were used to assess 95% confidential intervals (CIs) of presenting symptoms, outcomes, and complications.
    RESULTS: A total of 59 studies comprising 1903 patients were included in the systematic review and meta-analysis. Gross total resection (GTR) rates ranged from 23.5% for ETOAs to 59.8% for MTAs. Overall recurrence rate after surgery was 20.7%. Progression-free survival (PFS) rates at 5 and 10 years were 75.5% and 49.1%, respectively. Visual acuity and proptosis improvement rates were 57.5% and 79.3%, respectively. Postoperative cranial nerve (CN) focal deficits were observed in 20.6% of cases. The overall cerebro-spinal fluid (CSF) leak rate was 3.9%, and other complications occurred in 13.9% of cases. MTAs showed the highest GTR rates (59.8%, 95%CI = 49.5-70.2%; p = 0.001) but were associated with increased CN deficits (21.0%, 95%CI = 14.5-27.6%). ETOAs had the lowest GTR rates (23.5%, 95%CI = 0.0-52.5%; p = 0.001), while combined ETOA and EEA had the highest CSF leak rates (20.3%, 95%CI = 0.0-46.7%; p = 0.551). ETOAs were associated with better proptosis improvement (79.4%, 95%CI = 57.3-100%; p = 0.002), while anatomical class I lesions were associated with better visual acuity (71.5%, 95%CI = 63.7-79.4; p = 0.003) and proptosis (60.1%, 95%CI = 38.0-82.2; p = 0.001) recovery. No significant differences were found in PFS rates between surgical approaches.
    CONCLUSIONS: Surgical treatment of SOMs aims to preserve visual function and improve proptosis. Different surgical approaches offer varying rates of GTR, complications, and functional outcomes. A multidisciplinary approach involving a skull base team is crucial for optimizing patient outcomes.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    通常需要手术来治疗结直肠癌(CRC)。医疗技术有了进步,提供各种方法来解决这种疾病。不同的手术是可用的,例如腹腔镜手术,单切口腹腔镜手术,经自然腔道内镜手术,和机器人手术。腹腔镜手术有几个好处,包括减少失血和缩短恢复时间。它还可以改善肺功能并最大程度地减少并发症。然而,它需要更多的时间来执行,并且在手术过程中出现并发症的风险更高。机器人手术提供了手术区域的三维视图,从而可以实现直肠手术的更高精度并进入难以到达的骨盆区域。该方法利用机器人技术,其减少手术时间并加速患者的恢复。有多种手术选择可用于治疗CRC;然而,腹腔镜手术和机器人手术提供了独特的优势,尽管他们自己的缺点。随着技术的不断发展,医疗技术将继续改进现有方法,同时提供新的选择,从而为患者带来更好的结果。与腹腔镜相比,机器人手术的手术转换率较低,学习曲线较短。然而,它也有一些缺点,例如更长的对接时间,缺乏触觉,和更高的成本。因此,手术方法的选择应取决于患者的特征,外科医生的偏好和专业知识,和可用的资源。目前,专业中心提供的机器人手术比开腹和腹腔镜手术更昂贵,耗时更长。尽管如此,与传统手术相比,它们被认为是安全可行的。机器人手术的短期结果更好,而长期术后并发症发生率保持相似。然而,需要在多个中心进行更多明确的随机对照试验,以验证机器人手术在开放式和腹腔镜手术中的应用.改善患者护理和预后是这篇关于CRC手术方法的综合文献综述的目标。
    Surgery is usually required to treat colorectal cancer (CRC). Medical technology has advanced, providing various approaches to tackle this disease. Different surgeries are available, such as laparoscopic surgery, single-incision laparoscopic surgery, natural orifice transluminal endoscopic surgery, and robotic surgery. Laparoscopic surgery has several benefits including reduced blood loss and shorter recovery time. It can also improve lung function and minimize complications. However, it requires more time to perform and has a higher risk of complications during the procedure. Robotic surgery provides a three-dimensional view of the surgical area allowing for greater precision in rectal surgeries and access to difficult-to-reach pelvic regions. This method utilizes robotics technology which reduces surgical time and speeds up recovery for patients. There are various surgical options available for treating CRC; however, laparoscopic surgery and robotic surgery offer unique advantages despite their own drawbacks. As technology continues to evolve, medical techniques will continue improving existing methods while providing new options resulting in better outcomes for patients. Compared to laparoscopy, robotic surgery has a lower rate of operative conversions and a shorter learning curve. However, it also has some drawbacks, such as a longer docking time, lack of tactile sensation, and higher cost. Therefore, the choice of surgical method should depend on patient characteristics, surgeon preference and expertise, and available resources. Currently, specialized centers offer robotic surgeries which are more expensive and take longer compared to open and laparoscopic approaches. Nonetheless, they are considered safe and feasible when compared to traditional surgery. Short-term outcomes for robotic surgeries are better, while long-term postoperative complication rates remain similar. However, there is a need for additional well-defined randomized control trials conducted across multiple centers to validate the use of robotic surgery over open and laparoscopic approaches. Improving patient care and outcomes is the objective of this comprehensive literature overview on surgical approaches for CRC.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Systematic Review
    背景:尽管许多文章报道了骨盆环和髋臼骨折手术后的并发症,缺乏并发症发生率和潜在危险因素的一般概述.本综述提供了骨盆环和髋臼骨折手术后与手术方法相关的并发症的全面总结。
    方法:使用关键词系统地搜索Pubmed和Embase数据库:骨盆骨折,髋臼骨折,固定,手术方法,并发症,和他们的同义词。提取的数据包括患者和骨折特征,手术方法,和术后并发症;手术部位感染(SSI),植入物相关并发症,马工会和非工会。使用描述性统计对研究数据进行总结。
    结果:22项研究(21项回顾性队列研究,其中三个比较,和一项随机对照试验)纳入本综述。所包括的手术入路的总体并发症发生率为:(改良的)Stoppa入路为17%,11%用于经皮固定,对于Kocher-Langenbeck方法,7%用于髂腹股沟入路,31%用于外固定。最常见的并发症是SSI(22%)和神经系统(31%)并发症。这是最常见的报告在患者治疗外固定器。手术入路的再次手术率相当(4-8%)。两项研究报告了风险因素,并确定了伴随的外伤,ICU住院时间延长和高体重指数是SSI的危险因素。
    结论:骨盆骨折的外固定与包括SSI和神经系统并发症在内的最高并发症发生率相关。尽管骨盆骨折手术后经常报告术后并发症,需要更多的研究来确定潜在的危险因素.这些将帮助外科医生进行(术前)决策和制定预防策略。
    BACKGROUND: Although many articles report complications after pelvic ring and acetabular fracture surgery, a general overview of complication rates and potential risk factors is lacking. The current review provides a comprehensive summary of the complications after pelvic ring and acetabular fracture surgery in relation to the surgical approach.
    METHODS: Pubmed and Embase databases were systematically searched using the key words: pelvic fracture, acetabular fracture, fixation, surgical approaches, complications, and their synonyms. Extracted data included patient and fracture characteristics, surgical approaches, and post-operative complications; surgical site infections (SSI), implant-related complications, malunion and non-union. Study data were summarized using descriptive statistics.
    RESULTS: Twenty-two studies (twenty-one retrospective cohort studies, of which three comparative, and one randomized controlled trial) were included in this review. The overall complication rates reported for the included surgical approaches were: 17% for the (Modified) Stoppa approach, 11% for percutaneous fixation, 5% for the Kocher-Langenbeck approach, 7% for the ilioinguinal approach and 31% for external fixation. The most frequent complications were SSI (22%) and neurological (31%) complications, which were most often reported in patients treated with an external fixator. Re-operation rates were comparable for the surgical approaches (4-8%). Two studies reported on risk factors and identified concomitant traumatic injuries, prolonged ICU stay and high body mass index as risk factors for SSI.
    CONCLUSIONS: External fixation of pelvic fractures is associated with highest complications rates including SSI\'s and neurological complications. Although post-operative complications are frequently reported after pelvic fracture surgery, more studies are needed that identify potential risk factors. These will assist the surgeon in (pre)operative decision making and development of preventive strategies.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:骨巨细胞瘤(GCTB)治疗自从denosumab从单纯的手术方法向多学科方法引入以来发生了变化,最近人们担心denosumab术后复发率更高。我们评估了肿瘤学,外科,桡骨远端GCTB的功能结果,并进行了批判性评价的系统文献综述。
    方法:我们纳入了三个肉瘤中心的76例桡骨远端GCTB患者(1990年至2019年)。中位随访时间为8.8年(2至23年)。七名患者接受了刮宫,38刮宫用佐剂,31例切除;20例有denosumab。
    结果:刮治后复发率为71%(5/7),32%(12/38)刮除后用佐剂,6%(2/31)切除后。中位复发时间为17个月(4~77个月)。用佐剂刮治治疗复发(11),切除(六),或刮宫(两个)。总的来说,84%(38/45)在一次病灶内手术后治愈。7例患者有12个月的新辅助denosumab(5至15)和6个月的辅助denosumab;2例复发(29%)。12例患者接受了6个月的新辅助治疗denosumab(4至10);5例复发(42%)。2例发生肺转移(2.6%),在denosumab之后都稳定。并发症发生率为18%(14/76,11需要手术)。在后续行动中,肌肉骨骼肿瘤学会评分中位数为28分(18至30分),简短表格36健康调查中位数为86(41至95),和手臂的中位残疾,肩膀,手为7.8(0至58)。
    结论:桡骨远端GCTB治疗可能由于腕关节解剖和功能的复杂性而偏离一般GCTB治疗。这项多中心研究和系统综述提出了关于手术治疗的新见解。病灶内手术导致桡骨远端GCTB的高复发率,还有额外的denosumab。然而,绝大多数患者,经反复刮治。引用这篇文章:BoneJtOpen2022;3(7):515-528。
    OBJECTIVE: Giant cell tumour of bone (GCTB) treatment changed since the introduction of denosumab from purely surgical towards a multidisciplinary approach, with recent concerns of higher recurrence rates after denosumab. We evaluated oncological, surgical, and functional outcomes for distal radius GCTB, with a critically appraised systematic literature review.
    METHODS: We included 76 patients with distal radius GCTB in three sarcoma centres (1990 to 2019). Median follow-up was 8.8 years (2 to 23). Seven patients underwent curettage, 38 curettage with adjuvants, and 31 resection; 20 had denosumab.
    RESULTS: Recurrence rate was 71% (5/7) after curettage, 32% (12/38) after curettage with adjuvants, and 6% (2/31) after resection. Median time to recurrence was 17 months (4 to 77). Recurrences were treated with curettage with adjuvants (11), resection (six), or curettage (two). Overall, 84% (38/45) was cured after one to thee intralesional procedures. Seven patients had 12 months neoadjuvant denosumab (5 to 15) and sixmonths adjuvant denosumab; two recurred (29%). Twelve patients had six months neoadjuvant denosumab (4 to 10); five recurred (42%). Two had pulmonary metastases (2.6%), both stable after denosumab. Complication rate was 18% (14/76, with 11 requiring surgery). At follow-up, median MusculoSkeletal Tumour Society score was 28 (18 to 30), median Short Form-36 Health Survey was 86 (41 to 95), and median Disability of Arm, Shoulder, and Hand was 7.8 (0 to 58).
    CONCLUSIONS: Distal radius GCTB treatment might deviate from general GCTB treatment because of complexity of wrist anatomy and function. Novel insights on surgical treatment are presented in this multicentre study and systematic review. Intralesional surgery resulted in high recurrence-rate for distal radius GCTB, also with additional denosumab. The large majority of patients however, were cured after repeated curettage. Cite this article: Bone Jt Open 2022;3(7):515-528.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    扩散张量成像技术已被认为是用于白质束的体内可视化的神经成像工具。然而,DTI不是脑肿瘤切除术前计划的常规程序。我们的研究旨在系统评估DTI的有效性和手术结果。电子数据库,PubMed/MEDLINE和Scopus,进行了相关研究。基于DTI在术前计划中的应用,对研究进行了系统综述。手术计划的修改,术前DTI数据在术中重新评估,以及手术决定的结果。根据纳入和排除标准选择了17项研究。大多数研究认为,使用DTI的术前计划可以改善术后神经缺陷,给予更大的切除率和缩短手术时间。结果还表明,术前DTI术中的重新评估有助于更好地可视化白质束移位。七项研究还表明,DTI修改了初始手术方法的手术决策以及肿瘤切除手术中GTR的发生率。DTI的利用可以提供关于白质束通路的重要信息,为了更好的手术方法,并最终降低手术后神经功能缺损的风险。
    The diffusion tensor imaging technique has been recognized as a neuroimaging tool for in vivo visualization of white matter tracts. However, DTI is not a routine procedure for preoperative planning for brain tumor resection. Our study aimed to systematically evaluate the effectiveness of DTI and the outcomes of surgery. The electronic databases, PubMed/MEDLINE and Scopus, were searched for relevant studies. Studies were systematically reviewed based on the application of DTI in pre-surgical planning, modification of operative planning, re-evaluation of preoperative DTI data intraoperatively, and the outcome of surgery decisions. Seventeen studies were selected based on the inclusion and exclusion criteria. Most studies agreed that preoperative planning using DTI improves postoperative neuro-deficits, giving a greater resection yield and shortening the surgery time. The results also indicate that the re-evaluation of preoperative DTI intraoperatively assists in a better visualization of white matter tract shifts. Seven studies also suggested that DTI modified the surgical decision of the initial surgical approach and the rate of the GTR in tumor resection surgery. The utilization of DTI may give essential information on white matter tract pathways, for a better surgical approach, and eventually reduce the risk of neurologic deficits after surgery.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号