Oral and maxillofacial surgery

口腔颌面外科
  • 文章类型: Journal Article
    口腔颌面部肿瘤术后组织缺损的游离皮瓣重建是重建手术的重要组成部分。确定皮瓣坏死的危险因素对于改善手术效果和患者生活质量至关重要。对2020年1月至2023年12月接受游离皮瓣重建的患者进行了回顾性研究。如果患者有全面的医疗记录和至少六个月的随访,则将其包括在内。我们排除了有皮瓣坏死史的人,不受控制的系统性疾病,不坚持术后护理,或同时进行恶性肿瘤治疗。人口统计数据,合并症,襟翼特性,收集手术细节,采用单因素分析和logistic回归检验进行分析.单因素分析未发现皮瓣坏死与高脂血症、淋巴结转移,或皮瓣类型。然而,糖尿病,口腔感染,白蛋白水平低于35g/L与皮瓣坏死显著相关。多因素logistic回归分析显示糖尿病使皮瓣坏死的几率增加了约九倍,口腔感染使其增加了十倍以上。糖尿病,口腔感染,在口腔颌面外科术后游离皮瓣重建中,低白蛋白水平是皮瓣坏死的重要危险因素。及时识别和管理这些因素对于减轻皮瓣坏死的风险至关重要。
    Free flap reconstruction for postoperative tissue defects in oral and maxillofacial tumors is a critical component of reconstructive surgery. Identifying risk factors for flap necrosis is essential for improving surgical outcomes and patient quality of life. A retrospective study was conducted on patients who underwent free flap reconstruction between January 2020 and December 2023. Patients were included if they had comprehensive medical records and at least a six-month follow-up. We excluded those with a history of flap necrosis, uncontrolled systemic diseases, non-adherence to postoperative care, or concurrent malignancy treatments. Data on demographics, comorbidities, flap characteristics, and operative details were collected and analyzed using univariate analysis and logistic regression tests. Univariate analysis did not find a significant correlation between flap necrosis and factors such as hyperlipidemia, lymph node metastasis, or flap type. However, diabetes mellitus, oral infections, and albumin levels below 35 g/L were significantly associated with flap necrosis. Multivariate logistic regression showed diabetes mellitus increased the odds of flap necrosis by approximately ninefold, and oral infection increased it by over tenfold. Diabetes mellitus, oral infection, and low albumin levels are significant risk factors for flap necrosis in free flap reconstruction after oral and maxillofacial surgery. Prompt identification and management of these factors are crucial to mitigate the risk of flap necrosis.
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  • 文章类型: Journal Article
    背景:近几十年来,口腔和颌面部环境中的术后谵妄(POD)获得了更多关注。由于医疗技术的进步,治疗的可能性扩大了对老年和虚弱患者的治疗。本文探讨了POD与口腔颌面外科的相关性,总结筛查和管理方案,并确定该手术领域的风险因素。
    方法:本综述遵循系统评价和荟萃分析(PRISMA-ScR)的首选报告项目的范围评价扩展。使用多个数据库进行了全面的文献检索,重点关注2002年至2023年发表的讨论口腔颌面外科手术中谵妄的文章。该审查事先在开放科学框架(https://osf.io/r2ebc)中注册。
    结果:从最初的644篇文章中,68符合纳入标准。这些研究强调了POD诊断方法的显著异质性。该审查确定了术前的多个风险因素,术中,以及影响POD发生的术后阶段。多元回归分析中的显著和独立危险因素被强调,创建POD发生的临床预测列表。
    结论:术前确定有POD风险的患者并在患者的整个住院期间积极改变这些风险是至关重要的。建议对高危患者实施非药物预防措施,以降低POD的发生率。未来的研究应专注于创建标准化的特定专业协议,其中包含经过验证的评估工具,并解决与POD相关的所有风险因素。
    BACKGROUND: Postoperative delirium (POD) in the oral and maxillofacial settings has gained more attention in recent decades. Due to advances in medical technology, treatment possibilities have expanded treatment for elderly and frail patients. This scoping review explores the correlation between POD and oral and maxillofacial surgery, summarizing screening and management protocols and identifying risk factors in this surgical field.
    METHODS: This review follows the Scoping Review extension of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA-ScR). A comprehensive literature search was performed using multiple databases, focusing on articles published from 2002 to 2023 that discuss delirium in oral and maxillofacial surgery settings. The review was registered beforehand in the Open Science Framework ( https://osf.io/r2ebc ).
    RESULTS: From the initial 644 articles, 68 met the inclusion criteria. These studies highlighted the significant heterogeneity in POD diagnosis methods. The review identifies multiple risk factors across the preoperative, intraoperative, and postoperative phases that influence the occurrence of POD. Significant and independent risk factors in multiple regression analysis were highlighted, creating a clinical prediction list for the occurrence of POD.
    CONCLUSIONS: It is crucial to preoperatively identify patients at risk for POD and actively modify these risks throughout the patient\'s hospital stay. Implementing nonpharmacological preventive measures for at-risk patients is recommended to decrease the incidence of POD. Future research should focus on creating standardized specialty-specific protocols incorporating validated assessment tools and addressing the full spectrum of risk factors associated with POD.
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  • 文章类型: Journal Article
    目的和背景口腔颌面外科是一个重要的医学专业,专注于诊断,治疗,预防影响口腔的疾病和伤害,下巴,和脸。在冰雹的特定研究领域中缺乏对该领域的认识。这项研究旨在评估知识,意识,以及医疗保健专业人员和公众对颌面外科的看法。方法本研究包括225名参与者,由牙科和医疗专业人员以及冰雹中的公众组成,沙特阿拉伯。采用了便利采样,参与者需要至少20岁,是冰雹的居民。经过验证的在线问卷,翻译成阿拉伯语,用于数据收集。结果78.2%的牙科专业人员了解口腔颌面外科专业。在普通人群和大多数医疗专业人员中,与颌面外科手术最常见的相关程序是损伤的治疗,骨折,和口腔的形态变化,下巴,和脸,85.8%的参与者报告。此外,60.9%的参与者认为颌面手术是唇裂矫正的适当转诊。结论该研究强调了目标人群中口腔颌面外科医师的作用。在225名参与者中,137名参与者(60.9%)选择了颌面外科专业进行手术干预以治疗唇裂。此外,75.1%(n=169)的参与者以前听说过口腔颌面外科,而24.9%(n=56)的人从未听说过这个专业。调查结果还显示,189名参与者不知道颌面外科医生负责治疗无法使用正畸治疗的严重畸形,如生长障碍,下颌发育不全和发育不全,和下颌的不对称性(下颌的前颌和后颌)。为了弥合这种知识差距,在普通民众和医疗保健专业人员中实施有针对性的教育举措和提高认识运动至关重要。通过提高对口腔颌面外科医生专业作用的认识和理解,患者护理可以优化,并可以确保向这些专家进行适当的转诊。临床意义这项研究表明,提高卫生专业人员和公众对口腔颌面外科的认识非常重要。提高对这一专业的理解可以导致更好的患者结果和早期转诊。
    Aim and background Oral and maxillofacial surgery is a crucial medical specialty focused on diagnosing, treating, and preventing diseases and injuries affecting the oral cavity, jaw, and face. There is a lack of awareness about this field in the specific study area of hail. This study aimed to assess the knowledge, awareness, and perception of maxillofacial surgery among healthcare professionals and the public. Methods The study included 225 participants, consisting of dental and medical professionals and the general public in Hail, Saudi Arabia. Convenience sampling was employed, and participants needed to be at least 20 years old and residents of Hail. A validated online questionnaire, translated into Arabic, was used for data collection. Results A proportion (78.2%) of dental professionals were aware of the specialty of oral and maxillofacial surgery. Among the general population and most medical professionals, the most commonly associated procedures with maxillofacial surgery were the treatment of injuries, bone fractures, and morphological changes in the mouth, jaw, and face, reported by 85.8% of the participants. Furthermore, 60.9% of the participants believed that maxillofacial surgery was the appropriate referral for cleft lip correction. Conclusion The study highlighted significant knowledge about the role of oral and maxillofacial surgeons among the target population. Out of the 225 participants, 137 participants (60.9%) chose the specialty of maxillofacial surgery for surgical intervention to treat cleft lips. Moreover, 75.1% (n = 169) of the participants had previously heard about oral and maxillofacial surgery, while 24.9% (n = 56) had never heard of this specialty. The findings also showed that 189 participants were not aware that a maxillofacial surgeon is responsible for treating severe deformities that cannot be eliminated using orthodontics, such as growth disorders, hypoplasia and hypoplasia of the lower jaw, and asymmetry of the lower jaw (prognathism and retrognathism of the jaw). To bridge this knowledge gap, it is crucial to implement targeted educational initiatives and awareness campaigns among both the general population and healthcare professionals. By increasing awareness and understanding of the specialized role of oral and maxillofacial surgeons, patient care can be optimized, and appropriate referrals to these specialists can be ensured. Clinical significance This study shows the importance of increasing awareness of oral and maxillofacial surgery among health professionals and the general public. Improved understanding of this specialty can lead to better patient outcomes and early referrals.
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  • 文章类型: Journal Article
    背景:评估印度人口口腔癌患者生活质量(QoL)的研究很少。口腔鳞状细胞癌(OSCC)患者的定期随访和QoL评估可以帮助制定全面的支持策略,以改善其QoL结果。目的和目的本研究旨在评估口腔癌患者的QoL并将QoL与人口统计学和治疗参数相关联。材料和方法该研究包括先前向口腔颌面外科报告的口腔癌患者。在治疗前后使用EORTCQLQ-C30和QLQ-HN43问卷进行QoL评估。临床人口统计细节,治疗数据,后续数据,和记录的平均QoL是从牙科信息档案软件中的患者记录中获取的。在治疗前和间隔一个月进行QoL评估,三个月,六个月,12个月,24个月,治疗后36个月。使用IBMSPSSStatisticsforWindows进行统计分析,版本23(2015年发布;IBMCorp.,Armonk,纽约,美国)。使用重复测量方差分析(ANOVA)来比较平均QoL评分和各个间隔的随访频率。卡方检验评估了性别之间平均QoL的差异,在不同的地点,以及初级闭合和移植物放置之间。显著性设定为小于0.05的p值。结果本科共报告90例OSCC患者。对90例(100%)患者进行了术前QoL评估。在这些病人中,41例(45%)已进行手术.41名患者中有25名(60%)对定期随访有反应,并对这些患者进行QoL评估。术后即刻阶段后,只有12例(48%)在3个月后报告.只有6人(24%)接受了12个月的随访,5人(20%)进行了为期两年的随访,1人(4%)接受了3年随访。OSCC治疗后随访次数持续减少(p=0.00)。治疗前,平均QoL指数为4.64。女性的术前QoL略高于男性,为4.76。得分为4.67(p=0.157)。OSCC治疗后立即,注意到QoL分数下降,平均得分为4.25(p=0.32)。切除后接受初次闭合的患者的术后QoL平均得分为4.9,而接受移植物放置的患者的平均得分为4.6(p=0.157)。结论本研究强调了口腔癌对患者生活质量的持久影响,并强调需要进行持续研究以探索有助于持续改善QoL的具体干预措施。它强调个性化,这类患者的整体护理方法。
    Background Studies evaluating the quality of life (QoL) among oral cancer patients in the Indian population are scarce. Regular follow-ups and QoL assessment in oral squamous cell carcinoma (OSCC) patients can aid in comprehensive support strategies to improve their QoL outcomes. Aim and objectives This study aimed to assess the QoL of oral cancer patients and correlate the QoL with demographic and treatment parameters.  Materials and methods The study included oral cancer patients who had previously reported to the Department of Oral and Maxillofacial Surgery. QoL assessment was done using the EORTC QLQ-C30 and QLQ-HN43 questionnaires before and after treatment. The clinico-demographic details, treatment data, follow-up data, and recorded mean QoL were procured from the patient records in Dental Information Archival Software. Assessment of QoL was done before treatment and at intervals of one month, three months, six months, 12 months, 24 months, and 36 months postoperatively after treatment. Statistical analysis was performed using IBM SPSS Statistics for Windows, Version 23 (released 2015; IBM Corp., Armonk, New York, United States). A repeated measures analysis of variance (ANOVA) was utilized for comparing the average QoL scores and frequency of follow-ups across various intervals. Chi-square tests assessed differences in mean QoL among genders, across different sites, and between primary closure and graft placement. The significance was set at a p-value of less than 0.05. Results A total of 90 OSCC patients had reported to the department. A preoperative assessment of QoL was done for 90 (100%) patients. Out of these patients, surgery has been performed on 41 (45%). Twenty-five out of 41 (60%) patients had responded to regular follow-up, and QoL was assessed for these patients. After the immediate postoperative phase, only 12 (48%) had reported after three months. Only six (24%) had a 12-month follow-up, five (20%) had a two-year follow-up, and one (4%) had a three-year follow-up. There was a constant decrease in the number of follow-ups after the treatment of OSCC (p=0.00). Prior to treatment, the mean QoL index was 4.64. Females had a slightly higher preoperative QoL of 4.76 compared to males, with a score of 4.67 (p=0.157). Immediately after the treatment of OSCC, a decline in QoL scores was noted, with a mean score of 4.25 (p=0.32). Patients who underwent primary closure after excision had a mean post-op QoL score of 4.9, while patients who underwent graft placement had a mean score of 4.6 (p=0.157). Conclusion This study highlights the enduring impact of oral cancer on a patient\'s quality of life and emphasizes the need for ongoing research to explore specific interventions that can contribute to sustained improvement in QoL. It emphasizes personalized, holistic care approaches for such patients.
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  • 文章类型: Journal Article
    背景/目标:自成立以来,尸体模型一直是全球牙科和医学教育的支柱。在澳大利亚,牙科学校的教育工作者是最早在口腔外科的正式教学中使用尸体猪头的人之一。此后,这种做法在大多数现代牙科课程中都不受欢迎。这项初步研究的目的是从学生的角度确定尸体猪模型在口腔外科培训中的实用性(格里菲斯大学,黄金海岸,澳大利亚)。方法:30名所有三年级牙科学生的参与者参加了两个小时的会议,其中包括30分钟的讲座,然后是90分钟的实践研讨会。讲座概述了学生在实践过程中的步骤和监督,并由颌面外科顾问提供。在研讨会结束时,参与者被要求匿名填写一份打印的问卷,其中有8个与他们的经历相关的问题.结果:在研讨会之前,三分之二(61%)的参与者认为他们在第三年的牙科学校课程中被教导过适当提高粘膜骨膜皮瓣的外科手术,尽管只有43%的学生协助专业住院医师举起粘膜骨膜皮瓣,而14%的学生报告自己进行了手术。几乎所有学生(96%)都同意猪模型对他们的牙科教育很有用,如果有机会,他们将再次使用该模型进行练习。问卷的完成率为93.33%。结论:这项初步研究表明,猪头呈现出一种有用的,学习基本口腔外科手术的低成本辅助手段。
    Background/Objectives: Cadaveric models have traditionally been a mainstay of dental and medical education worldwide since their inception. In Australia, educators at dental schools were among the first to use cadaveric porcine heads in formal teaching in oral surgery. This practice has since fallen out of favour in most modern dental curricula. The aim of this pilot study was to determine the utility of cadaveric porcine models for oral surgery training from a student perspective (Griffith University, Gold Coast, Australia). Methods: Thirty participants who were all third-year dental students attended a two-hour session comprising a 30 min lecture followed by a 90 min practical workshop. The lecture outlined the steps and supervision of students during the practical and was provided by a consultant maxillofacial surgeon. At the conclusion of the workshop, participants were asked to anonymously complete a printed questionnaire with eight questions related to their experience. Results: Prior to the workshop, two-thirds (61%) of participants felt that they had been taught the surgical procedure for raising mucoperiosteal flaps adequately in their dental school curriculum during their third year, although only 43% of students had assisted specialty residents in raising a mucoperiosteal flap and 14% reported having performed the procedure themselves. Almost all students (96%) agreed that the porcine model was useful for their dental education and that they would practice the exercise using the model again if provided with the opportunity. The questionnaire had a 93.33% completion rate. Conclusions: This pilot study indicates that porcine heads present a useful, low-cost adjunct in the learning of basic oral surgical procedures.
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  • 文章类型: Journal Article
    下颌前区的外科手术需要对复杂的解剖结构有深刻的了解,以确保患者的安全。舌孔(LF)及其骨内管是关键结构,为精神区域提供血管和神经支持。LF的患病率被广泛认可,人口之间的差异。
    该研究涉及650名成年参与者。使用高分辨率锥形束计算机断层扫描(CBCT)收集数据,并进行了统计分析,建立评分者之间的协议。
    人口有不同的年龄分布,男性占53.23%,女性占46.77%。正中舌管见于上、下(65.38%)。大多数参与者有舌侧管(60.92%)。最普遍的舌孔为4(30.62%)。研究发现性别与LF直径之间没有显着关联,分布在不同的行进方向,或LF位置。然而,雄性的直径稍大。
    这些发现为基于解剖位置的LF变化提供了有价值的见解,不同年龄组的测量结果无统计学显著差异.这些知识有助于口腔颌面外科领域的发展,确保更好的患者结果。
    UNASSIGNED: Surgical procedures in the anterior mandibular region require a profound understanding of the complex anatomical structures to ensure patient safety. The lingual foramen (LF) and its intra-osseous canal are pivotal structures, supplying vascular and neural support to the mental region. The prevalence of LF is widely recognized, with variations among populations.
    UNASSIGNED: The study involved 650 adult participants. Data were collected using high-resolution cone-beam computed tomography (CBCT), and statistical analysis was conducted, establishing inter-rater agreement.
    UNASSIGNED: The population had a varied age distribution, with males comprising 53.23% and females comprising 46.77%. The median lingual canal was found in the Supra and Infra spinosum (65.38%). Most participants had lateral lingual canals (60.92%). The most prevalent lingual foramina was 4 (30.62%). The study found no significant associations between gender and LF diameter, distribution in different travel directions, or LF locations. However, males had a slightly larger diameter.
    UNASSIGNED: The findings provide valuable insights into LF variations based on anatomical locations, and there were no statistically significant differences in measurements across different age groups. This knowledge contributes to the evolving field of oral and maxillofacial surgery, ensuring better patient outcomes.
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  • 文章类型: Journal Article
    当前研究的目的是评估和深入了解参加Qassim大学临床课程的牙科学生对口腔颌面外科(OMFS)专业的看法。在卡西姆大学的牙科诊所进行了一项基于调查的横断面研究,经过大学牙科研究中心的批准。该研究针对的人群包括Qassim大学注册的80名牙科实习生和本科生(BDS)。从每个学年(第三年到实习生),随机选择了20名学生,确保男性和女性部门的代表。在分析了牙科学生实习生和班级年的数据后,结果发现,关于问题3:"你认为口腔颌面外科医师在实践中最常执行的手术是什么?",没有统计学上显著的关联(P=0.859a).在实习生和牙科学生中,绝大多数人认为提取第三磨牙是最常见的手术。所报告的比例最低(70.4%)为实习生班,而在四年级学生中报告的百分比最高(91.7%)。牙科学生对OMFS的看法在本科培训期间发生了变化。通过对这些看法有更深入的理解,专门从事OMFS的学术教师可以提高他们教育学生的能力,反过来,加强整体专业。
    The objective of the current research was to assess and gain insight into the perceptions held by dental students enrolled in the clinical program at Qassim University regarding the specialty of oral and maxillofacial surgery (OMFS). A survey-based cross-sectional study was carried out at the dental clinics of Qassim University, following approval from the Dental Research Center of the university. The study targeted a population consisting of 80 dental interns and undergraduate students (BDS) enrolled at Qassim University. From each academic year (third year to interns), a random selection of 20 students was made, ensuring representation from both male and female sections. Upon analyzing the data regarding the intern and class year of dental students, it was found that there were no statistically significant associations with regard to question 3: \"What do you perceive as the most commonly performed procedure by oral and maxillofacial surgeons in practice?\" (P = 0.759a). Among intern and dental students, a significant majority identified extraction of the third molars as the most frequent procedure carried out. The lowest percentage (70.4%) was reported among the intern classes, whereas the highest percentage (91.7%) was reported among the fourth-year students. The perceptions of dental students toward OMFS undergo changes during their undergraduate training. By gaining a deeper understanding of these perceptions, the academic faculty specialized in OMFS can enhance their ability to educate students and, in turn, strengthen the overall specialty.
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  • 文章类型: Journal Article
    背景:在重建手术中,游离皮瓣手术的有效教学有待改进。需要容易获得和广泛获得的培训,而没有高财务成本或道德问题,同时仍然提供现实的体验。我们的目的是为微血管皮瓣开发适当的训练模型。
    方法:我们确定了猪半头的可用性最合适,成本,和现实主义。这些主要是由食品工业产生的,所以不需要牺牲动物,从动物福利的角度来看,它更符合道德。我们评估了作为皮瓣供体部位的适用性,并分析了51个标本的血管解剖结构。
    结果:解剖评估显示可靠且恒定的血管解剖结构,允许设计一个皮瓣模型,可以有效地说明微血管皮瓣手术的整个过程。该过程分为6个关键步骤。在标记距口腔外侧角5.3cm的血管蒂后,可以收获皮瓣。皮肤岛设计和随后的组织解剖,直到筋膜皮瓣凸起,类似于径向瓣。皮瓣收获完成后,它可以自由转移进行缺损重建。微血管吻合可以在宫颈区域的受体血管上进行,难度可以单独调整。
    结论:所开发的训练模型在外科现实性方面是一个合理的折中方案,可用性,说教价值,和成本/时间效率。我们相信这是一个强大而有效的工具,具有改善外科教育和培训的巨大潜力。
    BACKGROUND: In reconstructive surgery, improvements are needed in the effective teaching of free flap surgery. There is a need for easily accessible and widely available training without high financial costs or ethical concerns while still providing a realistic experience. Our aim was to develop an appropriate training model for microvascular flaps.
    METHODS: We identified pig head halves as most appropriate regarding availability, cost, and realism. These accrue largely by the food industry, so no animals need to be sacrificed, making it more ethical from an animal welfare perspective. We evaluated the suitability as flap donor site and analyzed the vascular anatomy of 51 specimens.
    RESULTS: Anatomical evaluation revealed a reliable and constant vascular anatomy, allowing the design of a flap model that can effectively illustrate the entire process of microvascular flap surgery. The process was divided into 6 key steps. The flap can be harvested after marking the vascular pedicle 5.3 cm from the lateral corner of the mouth. Skin island design and subsequent tissue dissection follow until a fasciocutaneous flap is raised, similar to a radial flap. Upon completion of flap harvesting, it can be freely transferred for defect reconstruction. Microvascular anastomosis can be performed on recipient vessels in the cervical region, and the difficulty can be individually adjusted.
    CONCLUSIONS: The developed training model is a reasonable compromise in terms of surgical realism, availability, didactic value, and cost/time effectiveness. We believe it is a powerful and effective tool with high potential for improving surgical education and training.
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  • 文章类型: Case Reports
    背景:单囊性成釉细胞瘤是一种罕见的成釉细胞瘤,其特点是缓慢的增长和相对局部的侵略性,主要起源是下颌骨的后部,它也指那些显示临床的囊性病变,射线照相,或颌骨囊肿的大体特征。
    方法:一名27岁女性患者主诉下颌骨广泛肿块,右唇和下巴严重肿胀和麻木。口腔检查显示右下颌骨磨牙区肿胀,颊板扩张。影像学和组织病理学特征与单囊性成釉细胞瘤的诊断一致。因此,手术切除了病灶,在术后5年随访期间,未发现临床或放射学复发。
    结论:虽然先前关于颌骨后部单囊性成釉细胞瘤的报道显示预后良好的病变表现为单眼实体,该病例报告了扩张性单囊性成釉细胞瘤的多房性外观和攻击行为。此外,虽然一些研究将单囊成釉细胞瘤的单眼外观与阻生牙齿联系起来,我们的病例提示先前存在的病变可能与患牙相关的多房单囊性成釉细胞瘤有创伤性联系.
    结论:该病例表现为罕见的多房单囊性成釉细胞瘤,尤其是受累的牙齿。它还表明了固体成釉细胞瘤向单囊性成釉细胞的潜在转化。
    BACKGROUND: Unicystic ameloblastomas are a rare variant of ameloblastomas, which are characterized by slow growth and being relatively locally aggressive, with the main site of origin being the posterior portion of the mandible, it also refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst.
    METHODS: A 27-year-old female patient presented with a chief complaint of extensive mass of mandible along with severe swelling and numbness of right lips and chin. The oral examination revealed a swelling in the molar region of the right mandible with buccal plate expansion. The radiographic and histopathologic features were consistent with the diagnosis of unicystic ameloblastoma. Consequently, the lesion was surgically removed, and no clinical or radiological recurrence was detected during 5 years post-operative follow-up.
    CONCLUSIONS: While previous reports of unicystic ameloblastoma in the posterior portion of the jaw showed favorable prognosis lesions appeared as a unilocular entity, this case reports multilocular appearance and aggressive behavior of expansive unicystic ameloblastoma. Furthermore, while some studies linked the unilocular appearance of unicystic ameloblastoma to impacted tooth, our case suggests a possible traumatic link of preexisting lesion into multilocular unicystic ameloblastoma related to impacted tooth.
    CONCLUSIONS: This case presents a rare multilocular unicystic ameloblastoma appearance, notably with impacted tooth involvement. It also indicates the potential transformation of solid ameloblastoma into unicystic ameloblastom.
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  • 文章类型: Journal Article
    钛仍然是骨接合材料领域的黄金标准。这也适用于小儿颅面手术。已经开发了各种可再吸收材料,以避免昂贵且有风险的二次操作来去除儿童中的金属。然而,这些可吸收材料都不能完全取代以前的黄金标准,钛,以令人满意的方式。这导致了对满足生物相容性要求的新型可再吸收骨合成材料的需求。稳定性,和均匀的再吸收。在我们之前的体外和体内工作中,我们能够证明钼满足了这些要求。为了进一步证实这些结果,我们对四头家猪进行了概念验证,每个都植入了可吸收的钼植入物。然后每天检查动物的局部炎症参数。54天后,随后用计算机断层扫描成像对动物实施安乐死。我们还切除了植入物以及周围的组织和部分脾脏,肝脏,和肾脏进行组织病理学评估。钼植入物也进行了金相分析和使用扫描电子显微镜。在手术前和手术后采集血样。在整个测试期间,没有动物显示出炎症的临床症状。组织病理学,发现了良好的组织相容性。54天后观察到降解的早期迹象,不足以进行大量吸收。根据类似的早期调查的结果,预计再吸收将具有更长的原位停留时间。
    Titanium continues to be the gold standard in the field of osteosynthesis materials. This also applies to pediatric craniofacial surgery. Various resorbable materials have already been developed in order to avoid costly and risky second operations to remove metal in children. However, none of these resorbable materials have been able to completely replace the previous gold standard, titanium, in a satisfactory manner. This has led to the need for a new resorbable osteosynthesis material that fulfills the requirements for biocompatibility, stability, and uniform resorption. In our previous in vitro and in vivo work, we were able to show that molybdenum fulfills these requirements. To further confirm these results, we conducted a proof of concept in four domestic pigs, each of which was implanted with a resorbable molybdenum implant. The animals were then examined daily for local inflammatory parameters. After 54 days, the animals were euthanized with subsequent computer tomography imaging. We also removed the implants together with the surrounding tissue and parts of the spleen, liver, and kidney for histopathological evaluation. The molybdenum implants were also analyzed metallographically and using scanning electron microscopy. A blood sample was taken pre- and post-operatively. None of the animals showed clinical signs of inflammation over the entire test period. Histopathologically, good tissue compatibility was found. Early signs of degradation were observed after 54 days, which were not sufficient for major resorption. Resorption is expected with longer in situ residence times based on results of similar earlier investigations.
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