目的:视网膜分支静脉阻塞(BRVO)的病理,视网膜循环系统疾病,与受影响的眼睛的单眼变形相关的视力障碍有关,但这些患者的双眼变形的关联尚不清楚。本研究旨在检查BRVO患者双眼变形的频率及其与临床特征的关系。
方法:本研究共纳入87例接受BRVO相关性黄斑水肿(ME)治疗的患者。在基线和开始抗血管内皮生长因子(VEGF)治疗后1和3个月,我们使用M-CHARTS®诊断工具量化了受影响的眼睛中的变形视和双眼变形视。
结果:在基线时,53和7例患者在受影响的眼睛中出现了变形视和双眼变形视,分别。尽管在开始抗VEGF治疗后视力显著提高,患眼的平均M-CHARTS评分与基线评分相比没有变化.3个月时,9例患者出现双眼变形;它与受影响眼睛的变形明显相关,95%的置信区间为0.021-0.122(β=0.306,p=0.006)。
结论:在BRVO-ME患者中,受累眼睛的变形可引起双眼变形。
OBJECTIVE: The pathology of branch retinal vein occlusion (BRVO), a retinal circulatory disease, is related to monocular metamorphopsia-related vision impairment of the affected eyes, but the association of binocular
metamorphopsia in such patients is unclear. This study aimed to examine the frequency of binocular metamorphopsia and its association with the clinical characteristics of patients with BRVO.
METHODS: A total of 87 patients who were treated for BRVO-associated macular edema (ME) were included in this study. At baseline and 1 and 3 months after the initiation of anti-vascular endothelial growth factor (VEGF) treatment, we quantified metamorphopsia in the affected eyes and binocular
metamorphopsia using the M-CHARTS® diagnostic tool.
RESULTS: At baseline, 53 and 7 patients had metamorphopsia in the affected eyes and binocular
metamorphopsia, respectively. Although the visual acuity improved significantly after the initiation of anti-VEGF treatment, the mean M-CHARTS score in the affected eyes did not change from the baseline score. At 3 months, 9 patients showed binocular
metamorphopsia; it was significantly associated with
metamorphopsia in the affected eyes with a 95% confidence interval of 0.021-0.122 (β = 0.306, p = 0.006).
CONCLUSIONS: Metamorphopsia in the affected eyes can cause binocular
metamorphopsia in patients with BRVO-ME.