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Abstract：
This study aimed to evaluate visual function and perform multimodal imaging on patients with focal choroidal excavation without any chorioretinal disease (idiopathic focal choroidal excavation [iFCE]). Seventeen eyes of 15 patients with iFCE (8 men, 7 women; mean ± standard deviation age, 56.0 ± 10.8 years) were assessed for visual function including visual acuity, metamorphopsia, aniseikonia, and retinal sensitivity. Multimodal imaging included optical coherence tomography (OCT), fundus autofluorescence (FAF), and OCT angiography. This study found that the maximum width and depth of the excavation were 597 ± 330 (238-1809) µm and 123 ± 45 (66-231) µm, respectively, and that FAF showed normal or hypoautofluorescence corresponding to iFCE. The fundus examination findings were stable during the follow-up period (96 ± 48 months). None of the eyes showed any abnormalities in central retinal sensitivity or aniseikonia. Metamorphopsia was detected using Amsler grid testing and M-CHARTS in two eyes. Therefore, this study is the first to quantitatively and qualitatively study metamorphopsia of patients with iFCE. Our results showed that most patients with iFCE did not have visual impairments, despite the presence of morphological changes in the outer retina and choroid.
摘要：
这项研究旨在评估没有任何脉络膜视网膜疾病的局灶性脉络膜开挖（特发性局灶性脉络膜开挖[iFCE]）患者的视觉功能并进行多模态成像。15例iFCE患者的17只眼（8名男性，7名女性；平均值±标准差年龄，56.0±10.8年）评估了视觉功能，包括视敏度，变态,aniseikonia,和视网膜敏感性。多模态成像包括光学相干断层扫描（OCT），眼底自发荧光（FAF），和OCT血管造影。这项研究发现，开挖的最大宽度和深度分别为597±330（238-1809）µm和123±45（66-231）µm，分别,FAF显示对应于iFCE的正常或低自发荧光。随访期间(96±48个月)眼底检查结果稳定。没有一只眼睛在中央视网膜敏感性或aniseikia方面表现出任何异常。使用Amsler网格测试和M-CHARTS在两只眼睛中检测到变形。因此,这项研究是首次定量和定性研究iFCE患者的变形。我们的结果显示，大多数iFCE患者没有视力障碍，尽管外视网膜和脉络膜存在形态变化。
