PDF(Pubmed)
Abstract：
UNASSIGNED: SMART syndrome is a rare complication of brain radiotherapy. This is the first described presentation of SMART syndrome with metamorphopsia, which responded to aspirin, verapamil, and high-dose L-arginine therapy.
UNASSIGNED: A 43-year-old man presented with 3 weeks of migraine headaches with metamorphopsia and complex visual hallucinations affecting the left lower quadrant of both visual fields. This occurred on a background of high-dose radiotherapy for right cerebellar astrocytoma 32 years ago. MRI brain demonstrated unilateral gyriform enhancement and FLAIR hyperintense cortical swelling in the right occipital lobe consistent with SMART syndrome.
UNASSIGNED: Unusual presentations of SMART syndrome exist and require consideration in all patients with focal neurological deficit post-brain radiotherapy. Validated diagnostic and treatment modalities for SMART syndrome are urgently required.
UNASSIGNED: A 43-year-old man presented with 3 weeks of migraine headaches with metamorphopsia and complex visual hallucinations affecting the left lower quadrant of both visual fields. This occurred on a background of high-dose radiotherapy for right cerebellar astrocytoma 32 years ago. MRI brain demonstrated unilateral gyriform enhancement and FLAIR hyperintense cortical swelling in the right occipital lobe consistent with SMART syndrome.
UNASSIGNED: Unusual presentations of SMART syndrome exist and require consideration in all patients with focal neurological deficit post-brain radiotherapy. Validated diagnostic and treatment modalities for SMART syndrome are urgently required.
摘要：
■SMART综合征是脑放疗的一种罕见并发症。这是首次描述的SMART综合征与变形视神经，对阿司匹林有反应，维拉帕米,和大剂量L-精氨酸治疗.
■一名43岁的男子出现3周的偏头痛，伴有变形视和复杂的视觉幻觉，影响两个视野的左下象限。这发生在32年前右小脑星形细胞瘤的高剂量放射治疗的背景下。MRI脑部显示右侧枕叶单侧回旋状增强和FLAIR高强度皮质肿胀，符合SMART综合征。
■所有脑放疗后局灶性神经功能缺损患者都存在SMART综合征的异常表现，需要考虑。迫切需要SMART综合征的有效诊断和治疗方式。
■一名43岁的男子出现3周的偏头痛，伴有变形视和复杂的视觉幻觉，影响两个视野的左下象限。这发生在32年前右小脑星形细胞瘤的高剂量放射治疗的背景下。MRI脑部显示右侧枕叶单侧回旋状增强和FLAIR高强度皮质肿胀，符合SMART综合征。
■所有脑放疗后局灶性神经功能缺损患者都存在SMART综合征的异常表现，需要考虑。迫切需要SMART综合征的有效诊断和治疗方式。
