Interdisciplinary collaboration

跨学科合作
  • 文章类型: Editorial
    肺健康和产妇保健的整合对于确保母亲和婴儿的最佳呼吸结果至关重要。怀孕会导致呼吸系统发生重大生理变化,增加肺部并发症和加重哮喘等疾病的风险。这篇社论强调了肺科医师和助产士之间协作护理的必要性,以有效地应对这些挑战。通过一起工作,医疗保健提供者可以制定全面的护理计划,尽早解决潜在的呼吸系统问题,监测和管理慢性病,并提供警惕的产后护理。加强这两个专业的教育和跨学科培训对于弥合护理差距和改善孕产妇和新生儿健康结果至关重要。这种综合方法得到了研究的支持,这些研究表明了协调护理模式在减少并发症和促进更好的健康结果方面的好处。
    The integration of pulmonary health and maternal care is critical for ensuring optimal respiratory outcomes for both mothers and their infants. Pregnancy induces significant physiological changes in the respiratory system, increasing the risk of pulmonary complications and exacerbating conditions such as asthma. This editorial emphasizes the necessity for collaborative care between pulmonologists and midwives to manage these challenges effectively. By working together, healthcare providers can develop comprehensive care plans that address potential respiratory issues early, monitor and manage chronic conditions, and provide vigilant postpartum care. Enhanced education and interdisciplinary training for both professions are essential for bridging the gaps in care and improving maternal and neonatal health outcomes. This integrated approach is supported by research demonstrating the benefits of coordinated care models in reducing complications and promoting better health outcomes.
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  • 文章类型: Journal Article
    纳米医学代表了生物医学应用中的一种变革性方法。本研讨旨在经由过程优势来划定纳米医学在生物医学范畴的运用,弱点,机遇,和威胁(SWOT)分析,以评估其在临床应用中的功效和潜力。
    SWOT分析框架被用来系统地审查和评估内部的优势和劣势,以及纳米医学的外部机遇和威胁。该方法提供了对潜在益处和挑战的平衡考虑。
    SWOT分析的结果表明,纳米药物在药物递送方面具有巨大潜力,诊断成像,和组织工程。尽管如此,它面临着巨大的障碍,如安全问题,环境问题,和高开发成本。确定了关键的发展领域,特别是关于其治疗潜力和长期影响的不确定性。
    纳米医学在推动医学创新方面具有广阔的前景。然而,成功的临床翻译需要解决安全性,成本,和监管挑战。跨学科协作和综合战略规划对于纳米医学的安全有效应用至关重要。
    UNASSIGNED: Nanomedicine represents a transformative approach in biomedical applications. This study aims to delineate the application of nanomedicine in the biomedical field through the strengths, weaknesses, opportunities, and threats (SWOT) analysis to evaluate its efficacy and potential in clinical applications.
    UNASSIGNED: The SWOT analysis framework was employed to systematically review and assess the internal strengths and weaknesses, along with external opportunities and threats of nanomedicine. This method provides a balanced consideration of the potential benefits and challenges.
    UNASSIGNED: Findings from the SWOT analysis indicate that nanomedicine presents significant potential in drug delivery, diagnostic imaging, and tissue engineering. Nonetheless, it faces substantial hurdles such as safety issues, environmental concerns, and high development costs. Critical areas for development were identified, particularly concerning its therapeutic potential and the uncertainties surrounding long-term effects.
    UNASSIGNED: Nanomedicine holds substantial promise in driving medical innovation. However, successful clinical translation requires addressing safety, cost, and regulatory challenges. Interdisciplinary collaboration and comprehensive strategic planning are crucial for the safe and effective application of nanomedicine.
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  • 文章类型: Journal Article
    有多个复杂问题的家庭经常与多个专业人员和组织打交道以寻求支持。综合社会护理据说可以防止经常出现的护理分散。我们确定了接受综合社会护理的家庭以及提供综合社会护理的专业人士所经历的促进者和障碍。
    我们根据Arksey和O\'Malley的框架进行了范围审查,使用以下数据库:PsycINFO,WebofScience核心合集,心理学与行为科学合集,CINAHL,PubMed,Medline此外,进行了专题分析。结果分为综合社会护理的促进因素和障碍。
    我们确定了278项研究,最终将16项纳入我们的范围审查。我们确定了主持人,包括:将正式护理与非正式网络联系起来,促进专业人员之间的合作,例如,成对工作,专业人员的自主权。我们确定了障碍,包括:时间限制,专业人员之外的任务,以及对组织间综合协作的抵制。这些发现可以促进社会综合护理的发展,作为支持面临多重复杂问题的家庭的一种有希望的方法。
    为了赋予家庭权力,综合社会关怀需要基于信任的系统方法。它涉及协调护理,共同决策,非正式网络和所有家庭成员的参与,包括孩子。
    UNASSIGNED: Families with multiple and complex problems often deal with multiple professionals and organizations for support. Integrated social care supposedly prevents the fragmentation of care that often occurs.We identified facilitators and barriers experienced by families receiving integrated social care and by the professionals who provide it.
    UNASSIGNED: We performed a scoping review following Arksey and O\'Malley\'s framework, using the following databases: PsycINFO, Web of Science Core Collection, Psychology and Behavioral Sciences Collection, CINAHL, PubMed, and Medline. Furthermore, conducted a thematic analysis. The results were divided into facilitators and barriers of integrated social care.
    UNASSIGNED: We identified 278 studies and finally included sixteen in our scoping review. We identified facilitators, including: linking formal care with informal networks, promoting collaboration among professionals e.g., working in pairs, and professionals autonomy. We identified barriers, including: time constraints, tasks outside professionals\' expertise, along with resistance to integrated collaboration among organizations. These findings can enhance the advancement of social integrated care as a promising approach to support families facing multiple and complex problems.
    UNASSIGNED: To empower families, integrated social care requires a systematic approach based on trust. It involves coordinated care, shared decision-making, informal networks and the participation of all family members, including children.
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  • 文章类型: Journal Article
    这篇综述文章评估了减少衰弱和痴呆住院老年人跌倒的策略的有效性和局限性。它探讨了现有的跌倒预防策略对急性容易跌倒和跌倒相关后果的队列的有效性。在MEDLINE进行了系统的文献检索,Embase,CINAHL,和PsycINFO,采用医学主题词(MeSH)确定2013年至2023年发表的关于患有痴呆和虚弱的住院老年人跌倒预防策略的研究.最初的643条记录被提炼成八篇文章,结构化跨学科床边回合(SIBR)作为一种值得注意的干预措施。SIBR通过促进改进的跨学科交流和护理计划,证明了跌倒的减少。然而,连续会议期间家庭参与的下降表明需要采取策略来维持家庭参与.研究结果提倡以患者为中心的干预措施,以解决该老年人群面临的认知和功能挑战。这篇综述提倡在医院环境中进行全面和包容性的研究,以改善虚弱的老年痴呆症患者的跌倒预防策略。
    This review article assesses the effectiveness and limitations of strategies to reduce falls among hospitalized older adults with frailty and dementia. It explores the efficacy of existing fall prevention strategies for a cohort that is acutely susceptible to falls and fall-related consequences. A systematic literature search was conducted across MEDLINE, Embase, CINAHL, and PsycINFO, employing Medical Subject Headings (MeSH) to identify studies on fall prevention strategies in hospitalized older adults with both dementia and frailty published from 2013 to 2023. The initial 643 records were distilled to eight articles, with Structured Interdisciplinary Bedside Rounds (SIBR) emerging as a notable intervention. SIBR demonstrated a reduction in falls by fostering improved interdisciplinary communication and care planning. However, a decline in family engagement during consecutive sessions suggests a need for strategies to sustain familial involvement. The findings advocate for patient-centered interventions that address the cognitive and functional challenges faced by this cohort of older adults. This review advocates for comprehensive and inclusive research in hospital environments to improve fall prevention strategies for frail older adults with dementia.
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  • 文章类型: Journal Article
    由于细菌遗传因素与抗生素滥用等外部影响之间的复杂相互作用,抗生素耐药性对全球公共卫生构成重大威胁。人工智能(AI)提供了解决这一危机的创新策略。例如,人工智能可以分析基因组数据以早期检测抗性标记,能够进行早期干预。此外,人工智能支持的决策支持系统可以通过根据患者数据和局部耐药模式推荐最有效的治疗方法来优化抗生素的使用。人工智能可以通过预测新化合物的功效和识别潜在的抗菌剂来加速药物发现。虽然取得了进展,挑战依然存在,包括数据质量,模型可解释性,和现实世界的实现。将人工智能与其他新兴技术相结合的多学科方法,比如合成生物学和纳米医学,可以为有效预防和减轻抗菌素耐药性铺平道路,为后代保留抗生素的功效。
    Antibiotic resistance poses a significant threat to global public health due to complex interactions between bacterial genetic factors and external influences such as antibiotic misuse. Artificial intelligence (AI) offers innovative strategies to address this crisis. For example, AI can analyze genomic data to detect resistance markers early on, enabling early interventions. In addition, AI-powered decision support systems can optimize antibiotic use by recommending the most effective treatments based on patient data and local resistance patterns. AI can accelerate drug discovery by predicting the efficacy of new compounds and identifying potential antibacterial agents. Although progress has been made, challenges persist, including data quality, model interpretability, and real-world implementation. A multidisciplinary approach that integrates AI with other emerging technologies, such as synthetic biology and nanomedicine, could pave the way for effective prevention and mitigation of antimicrobial resistance, preserving the efficacy of antibiotics for future generations.
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  • 文章类型: Journal Article
    背景:儿童虐待是一个全球性问题,使儿童面临精神疾病的风险,药物滥用,过早死亡。跨学科合作对于预防和检测虐待儿童很重要。在挪威,儿童接受普遍的预防性健康评估,并在儿童和家庭健康诊所接受专业公共卫生护士的免费随访护理。这些护士进行定期检查和家访,以监测儿童是否有虐待的迹象。
    目的:本研究的目的是描述儿童和家庭保健诊所的公共卫生护士如何遵循国家临床指南来预防和发现儿童虐待,特别关注临床程序和跨学科合作。此外,我们的目标是确定与儿童虐待识别相关的因素。
    方法:对10月24日至12月31日在初级保健工作的公共卫生护士进行了一项横断面在线调查,2022年。与0-5岁儿童一起工作并与家人协商的公共卫生护士有资格参加,产生554个响应。这项研究采用了描述性分析,包括频率,百分比和平均值,以及两步逻辑回归分析。这项研究得到了有关当局的批准,并通过问卷填写获得知情同意。
    结果:本研究中的公共卫生护士表现出对指南的强烈坚持,并利用各种综合评估程序来监测儿童的健康状况,增长,和发展。然而,与其他专业人士的合作有限且不频繁,如儿童保护服务,全科医生,和医院。大多数公共卫生护士报告偶尔怀疑虐待儿童,年龄和在儿童和家庭诊所的经验影响了这些怀疑。年长的公共卫生护士更有可能怀疑身体暴力,而那些有不到两年经验的人报告说,怀疑虐待的经验较少。额外的教育增加了怀疑性暴力的可能性。
    结论:这项研究提供了对挪威公共卫生护士在儿童和家庭诊所中发现和预防儿童虐待行为的见解。虽然坚持准则很强烈,虐待的嫌疑相对罕见。各机构之间的合作对于解决虐待儿童的问题至关重要。年龄和经验可能会影响虐待的检测。改进协作,有针对性的指导方针,需要持续的专业发展来加强儿童保护。
    BACKGROUND: Child maltreatment is a global problem that puts children at risk of mental illness, substance abuse, and premature death. Interdisciplinary collaboration is important in preventing and detecting child maltreatment. In Norway, children undergo universal preventive health assessments and receive complimentary follow-up care from specialized public health nurses in child and family health clinics. These nurses conduct regular check-ups and home visits to monitor children for signs of maltreatment.
    OBJECTIVE: The objective of this study is to describe how public health nurses at child and family health clinics follow the National Clinical Guidelines to prevent and detect child maltreatment, with a particular focus on clinical procedures and interdisciplinary collaboration. Furthermore, we aim to determine factors that are associated with identification of child maltreatment.
    METHODS: A cross-sectional online survey was conducted among public health nurses working in primary care between October 24th and December 31st, 2022. Public health nurses who worked with children aged 0-5 years and had consultations with families were eligible to participate, resulting in 554 responses. The study employed descriptive analysis, including frequency, percentage and mean, as well as a two-step logistic regression analysis. The study was approved by the relevant authority, and informed consent was obtained through questionnaire completion.
    RESULTS: The public health nurses in this study displayed strong adherence to the guidelines and utilized various comprehensive assessment procedures to monitor child well-being, growth, and development. However, there was limited and infrequent collaboration with other professionals, such as child protection services, general practitioners, and hospitals. Most public health nurses reported occasional suspicion of child maltreatment, with age and years of experience in child and family clinics influencing these suspicions. Older public health nurses were more likely to suspect physical violence, while those with less than two years of experience reported less experience in suspecting maltreatment. Additional education increased the probability of suspecting sexual violence.
    CONCLUSIONS: This study provides insights into the practices of public health nurses in Norway regarding the detection and prevention of child maltreatment in child and family clinics. While adherence to guidelines is strong, suspicion of maltreatment is relatively rare. Collaboration across agencies is crucial in addressing child maltreatment. Age and experience may influence the detection of maltreatment. Improved collaboration, targeted guidelines, and ongoing professional development are needed to enhance child protection.
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  • 文章类型: Case Reports
    该病例报告使用全外显子组测序(WES)记录了一名27岁女性患有复杂的神经发育障碍(NDD)的诊断和解决方法。该患者被送往精密医学诊所,患有多种诊断,包括智力残疾,自闭症谱系障碍(ASD),强迫症(强迫症),Tics,癫痫发作,与链球菌感染相关的儿科自身免疫性神经精神疾病(PANDAS)。尽管该患者先前进行了染色体微阵列和几种单基因测试,该患者症状的根本原因仍然难以捉摸。WES揭示了HNRNPU基因的致病性错义突变,与HNRNPU相关的神经发育障碍(HNRNPU-NDD)和发育性和癫痫性脑病-54(DEE54,OMIM:#617391)相关。在这个诊断之后,其他治疗临床医生确定了基因检测的其他适应症,然而,由于WES数据很容易获得,临床团队能够重新分析WES数据以解决他们的询问,而不需要额外的检查.这强调了WES在加速诊断中的关键作用,降低成本,并在患者一生中提供持续的临床效用。初级保健环境中的可访问WES数据可以通过通知未来的遗传查询来增强患者护理。加强护理协调,促进精准医学干预,从而减轻家庭和医疗保健系统的负担。
    This case report chronicles the diagnostic odyssey and resolution of a 27-year-old female with a complex neurodevelopmental disorder (NDD) using Whole Exome Sequencing (WES). The patient presented to a precision medicine clinic with multiple diagnoses including intellectual disability, autism spectrum disorder (ASD), obsessive-compulsive disorder (OCD), tics, seizures, and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS). Although this patient previously had chromosomal microarray and several single-gene tests, the underlying cause of this patient\'s symptoms remained elusive. WES revealed a pathogenic missense mutation in the HNRNPU gene, associated with HNRNPU-related neurodevelopmental disorder (HNRNPU-NDD) and developmental and epileptic encephalopathy-54 (DEE54, OMIM: # 617391). Following this diagnoses, other treating clinicians identified additional indications for genetic testing, however, as the WES data was readily available, the clinical team was able to re-analyze the WES data to address their inquiries without requiring additional tests. This emphasizes the pivotal role of WES in expediting diagnoses, reducing costs, and providing ongoing clinical utility throughout a patient\'s life. Accessible WES data in primary care settings can enhance patient care by informing future genetic inquiries, enhancing coordination of care, and facilitating precision medicine interventions, thereby mitigating the burden on families and the healthcare system.
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  • 文章类型: Editorial
    在《世界临床病例杂志》上发表的这项研究中,Wang和Long利用先进的机器学习方法进行了定量分析,以描绘重症监护病房获得性虚弱(ICU-AW)的风险因素。该研究采用多层感知器神经网络来准确预测ICU-AW的发生率,重点关注ICU住院时间和机械通气等关键变量。这项研究标志着将机器学习应用于临床诊断的重大进展。为重症监护中的预测医学提供了新的范例。它强调了在临床实践中整合人工智能技术以增强患者管理策略的重要性,并呼吁跨学科合作以推动医疗保健创新。
    In the research published in the World Journal of Clinical Cases, Wang and Long conducted a quantitative analysis to delineate the risk factors for intensive care unit-acquired weakness (ICU-AW) utilizing advanced machine learning methodologies. The study employed a multilayer perceptron neural network to accurately predict the incidence of ICU-AW, focusing on critical variables such as ICU stay duration and mechanical ventilation. This research marks a significant advancement in applying machine learning to clinical diagnostics, offering a new paradigm for predictive medicine in critical care. It underscores the importance of integrating artificial intelligence technologies in clinical practice to enhance patient management strategies and calls for interdisciplinary collaboration to drive innovation in healthcare.
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  • 文章类型: Journal Article
    跨学科的沟通和合作对于照顾患有多种长期疾病(MLTC)的人至关重要,但往往被认为是不足的。通过复杂性科学的镜头,本研究旨在通过检查门诊医院环境中的跨学科沟通和合作,解释医疗保健专业人员(HCP)如何适应MLTC患者护理中出现的新情况.我们使用恒定的比较方法分析了来自七个焦点小组的21个HCP的转录数据,以产生建构主义的理论,即“在医院门诊环境中,针对多种长期疾病的患者进行跨学科交流和合作”。我们的理论阐明了沟通和合作的各种途径。为什么,when,以及团队成员如何选择协作影响是否以及在何种程度上实现了量身定制的护理。由于内在化的规则,这个过程有很大的可变性和不可预测性,例如对偏离准则的适当性的信念,以及跨专业身份的存在。我们确定了影响护理团队动态的组织结构,例如合作的时间和经济补偿。当我们努力为MLTC患者提供量身定制的护理时,我们的理论为未来的努力提供了有希望的途径。
    Interdisciplinary communication and collaboration are crucial in the care of people with multiple long-term conditions (MLTCs) yet are often experienced as insufficient. Through the lens of complexity science, this study aims to explain how healthcare professionals (HCPs) adapt to emerging situations in the care of patients with MLTC by examining interdisciplinary communication and collaboration in the outpatient hospital setting. We used the constant comparative method to analyze transcribed data from seven focus groups with twenty-one HCPs to generate a constructivist grounded theory of \'interdisciplinary communication and collaboration in the outpatient setting of the hospital for patients with multiple long-term conditions\'. Our theory elucidates the various pathways of communication and collaboration. Why, when, and how team members choose to collaborate influences if and to what degree tailored care is achieved. There is great variability and unpredictability to this process due to internalized rules, such as beliefs on the appropriateness to deviate from guidelines, and the presence of an interprofessional identity. We identified organizational structures that influence the dynamics of the care team such as the availability of time and financial compensation for collaboration. As we strive for tailored care for patients with MLTC, our theory provides promising avenues for future endeavors.
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  • 文章类型: Journal Article
    抗菌素耐药性(AMR)是东地中海地区(EMR)的主要威胁,卫生系统薄弱,以及滥用抗菌药物。本文旨在讨论如何跨学科的行动和协作,特别是通过抗菌药物管理(AMS)和单一健康方法,可以有效地解决EMR中的AMR。审查的重点是成功的AMS倡议和在EMR内的国家采用“一个健康”方法,包括海湾合作委员会(GCC)埃及,伊朗,乔丹,和巴基斯坦。目标是强调在打击AMR方面取得进展的潜力,并确定加强跨学科合作的挑战和机遇。结果展示了在各个EMR国家/地区成功的AMS计划和OneHealth计划,展示他们应对AMR挑战的潜力。本文还讨论了这些国家面临的挑战,例如有限的资源,支离破碎的卫生系统,和知识差距。此外,通过区域合作加强跨学科行动的机会,国际伙伴关系,并对研究和创新进行了概述。总之,本文强调了在EMR中全面协作应对AMR的重要性。它主张将“一个健康”方法作为指导这些努力的关键框架,促进协调行动,改进监控,负责任的抗菌药物使用,加强跨学科合作,有效缓解AMR的威胁。
    Antimicrobial resistance (AMR) is a major threat in the Eastern Mediterranean region (EMR) due to factors such as the high prevalence of infectious diseases, weak health systems, and the misuse of antimicrobials. This paper aims to discuss how interdisciplinary action and collaboration, specifically through antimicrobial stewardship (AMS) and the One Health approach, can effectively address AMR in the EMR. The review focuses on successful AMS initiatives and the adoption of the One Health approach in countries within the EMR, including the Gulf Cooperation Countries (GCC), Egypt, Iran, Jordan, and Pakistan. The goal is to highlight the potential for progress in combating AMR and identify challenges and opportunities for strengthening interdisciplinary collaboration. The results showcase successful AMS programs and One Health initiatives in various EMR countries, demonstrating their potential to address AMR challenges. The paper also discusses the challenges faced by these nations, such as limited resources, fragmented health systems, and knowledge gaps. Additionally, opportunities for enhancing interdisciplinary action through regional cooperation, international partnerships, and research and innovation are outlined. In conclusion, this paper emphasizes the importance of a comprehensive and collaborative response to combat AMR in the EMR. It advocates for the One Health approach as a crucial framework to guide these efforts, promoting coordinated action, improved surveillance, responsible antimicrobial use, and enhanced interdisciplinary collaboration to effectively mitigate the threat of AMR.
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