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Abstract：
Antimicrobial resistance (AMR) is a major threat in the Eastern Mediterranean region (EMR) due to factors such as the high prevalence of infectious diseases, weak health systems, and the misuse of antimicrobials. This paper aims to discuss how interdisciplinary action and collaboration, specifically through antimicrobial stewardship (AMS) and the One Health approach, can effectively address AMR in the EMR. The review focuses on successful AMS initiatives and the adoption of the One Health approach in countries within the EMR, including the Gulf Cooperation Countries (GCC), Egypt, Iran, Jordan, and Pakistan. The goal is to highlight the potential for progress in combating AMR and identify challenges and opportunities for strengthening interdisciplinary collaboration. The results showcase successful AMS programs and One Health initiatives in various EMR countries, demonstrating their potential to address AMR challenges. The paper also discusses the challenges faced by these nations, such as limited resources, fragmented health systems, and knowledge gaps. Additionally, opportunities for enhancing interdisciplinary action through regional cooperation, international partnerships, and research and innovation are outlined. In conclusion, this paper emphasizes the importance of a comprehensive and collaborative response to combat AMR in the EMR. It advocates for the One Health approach as a crucial framework to guide these efforts, promoting coordinated action, improved surveillance, responsible antimicrobial use, and enhanced interdisciplinary collaboration to effectively mitigate the threat of AMR.
摘要：
抗菌素耐药性(AMR)是东地中海地区(EMR)的主要威胁,卫生系统薄弱，以及滥用抗菌药物。本文旨在讨论如何跨学科的行动和协作，特别是通过抗菌药物管理(AMS)和单一健康方法，可以有效地解决EMR中的AMR。审查的重点是成功的AMS倡议和在EMR内的国家采用“一个健康”方法，包括海湾合作委员会（GCC）埃及,伊朗,乔丹,和巴基斯坦。目标是强调在打击AMR方面取得进展的潜力，并确定加强跨学科合作的挑战和机遇。结果展示了在各个EMR国家/地区成功的AMS计划和OneHealth计划，展示他们应对AMR挑战的潜力。本文还讨论了这些国家面临的挑战，例如有限的资源，支离破碎的卫生系统，和知识差距。此外,通过区域合作加强跨学科行动的机会，国际伙伴关系,并对研究和创新进行了概述。总之,本文强调了在EMR中全面协作应对AMR的重要性。它主张将“一个健康”方法作为指导这些努力的关键框架，促进协调行动，改进监控,负责任的抗菌药物使用，加强跨学科合作，有效缓解AMR的威胁。
