Hoarseness

声音嘶哑
  • 文章类型: Journal Article
    在他们的工作中,教师可能会受到导致不同健康问题的条件。这项研究调查了858名教师(528名女性;年龄44.0±9.67岁)的代表性样本中的职业健康失调,分为三组具有特定职业要求的教师:专业体育教师(专业PETs),课堂教师,和专业教师。使用慢性健康障碍问卷记录过去12个月的健康障碍数量。不同类型教师之间的差异,控制性别和年龄,采用二元逻辑回归分析。结果显示,89%的教师患感冒是最常见的健康问题,其次是58%的下背部问题,57%的头痛,51%为声音嘶哑,43%的脖子问题。二元逻辑回归显示,专业PETs是健康风险最高的组。他们患肌肉骨骼或听力障碍的可能性是其他两组教师的两倍。他们也更有可能患有声音嘶哑。了解这些不同的健康挑战对于开发有针对性的干预措施和强大的支持系统至关重要。这些干预措施应包括旨在提高对健康风险因素的认识的举措,实施损伤干预措施和声带卫生计划,进行人体工程学调整,和促进自我保健意识(精神和身体)。鉴于目前教师职业正在努力应对劳动力老化和教师短缺的问题,解决这些挑战对教学专业人员的持续福祉至关重要。
    During the course of their work, teachers may be subjected to conditions that cause different health problems. This study examines occupational health disorders in a representative sample of 858 teachers (528 female; age 44.0 ± 9.67 years) divided into three groups of teachers with specific occupational requirements: specialist physical education teachers (specialist PETs), classroom teachers, and specialist teachers. The number of health disorders in the last 12 months was recorded using the Chronic Health Disorders Questionnaire. The differences between the different types of teachers, controlled for sex and age, were analyzed using binary logistic regression. The results showed that 89% of teachers experienced colds as the most frequently reported health problem, followed by 58% for lower back problems, 57% for headaches, 51% for hoarseness, and 43% for neck problems. A binary logistic regression showed that specialist PETs were the group with the highest health risk. They were about twice as likely to have musculoskeletal or hearing disorders than the other two groups of teachers. They were also significantly more likely to suffer from hoarseness. Understanding these different health challenges is critical to developing targeted interventions and robust support systems. These interventions should include initiatives aimed at raising awareness of health risk factors, implementing injury interventions and vocal cord hygiene programs, making ergonomic adjustments, and promoting awareness of self-care (both mental and physical). Given that the teaching profession is currently struggling with an aging workforce and a shortage of teachers, addressing these challenges is critical to the continued well-being of the teaching professionals.
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  • 文章类型: Journal Article
    许多讲师会出现声音问题,如声音嘶哑。然而,研究语音质量如何影响听众的感知,理解,而口语的保留仅限于少量的音频实验。我们旨在通过使用视听虚拟现实(VR)来调查讲师的声音嘶哑对大学生的影响来解决这一差距。倾听的努力,听的印象。50名参与者沉浸在一个虚拟的研讨室中,他们参与了双重任务范式。他们听了一位虚拟女教授的叙述,用典型或嘶哑的声音说话的人。同时,参与者执行了次要任务。结果显示,与典型的声音相比,嘶哑的声音显着延长了次要任务响应时间,表明倾听的努力增加。主观上,参与者认为嘶哑的声音更烦人,努力去倾听,阻碍他们的认知表现。语音质量对听到的文本回忆没有影响,这表明,虽然声音嘶哑可能会损害口语处理的某些方面,这不一定会导致信息保留减少。总之,我们的发现强调了在讲师中促进声乐健康的重要性,这可能有助于增强学习空间中的听力条件。
    Many lecturers develop voice problems, such as hoarseness. Nevertheless, research on how voice quality influences listeners\' perception, comprehension, and retention of spoken language is limited to a small number of audio-only experiments. We aimed to address this gap by using audio-visual virtual reality (VR) to investigate the impact of a lecturer\'s hoarseness on university students\' heard text recall, listening effort, and listening impression. Fifty participants were immersed in a virtual seminar room, where they engaged in a Dual-Task Paradigm. They listened to narratives presented by a virtual female professor, who spoke in either a typical or hoarse voice. Simultaneously, participants performed a secondary task. Results revealed significantly prolonged secondary-task response times with the hoarse voice compared to the typical voice, indicating increased listening effort. Subjectively, participants rated the hoarse voice as more annoying, effortful to listen to, and impeding for their cognitive performance. No effect of voice quality was found on heard text recall, suggesting that, while hoarseness may compromise certain aspects of spoken language processing, this might not necessarily result in reduced information retention. In summary, our findings underscore the importance of promoting vocal health among lecturers, which may contribute to enhanced listening conditions in learning spaces.
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  • 文章类型: Journal Article
    背景:这项随机对照试验旨在评估术前吸入布地奈德联合静脉注射地塞米松对甲状腺切除术患者全麻术后咽喉痛(POST)的疗效。
    方法:择期甲状腺切除术患者随机分为静脉注射地塞米松组(A组)和雾化吸入布地奈德联合静脉注射地塞米松组(B组)。所有患者均行全身麻醉。POST的发生率和严重程度,声音嘶哑,术后1、6、12和24小时咳嗽进行评价和比较。
    结果:A组和B组分别有48和49例患者,分别。B组术后6、12、24hPOST发生率明显低于A组(P<0.05)。此外,B组24小时咳嗽的发生率明显降低(P=0.047)。与A组相比,POST的严重程度在6时显著降低(P=.027),12(P=.004),休息24小时(P=0.005),在6(P=0.002),12(P=.038),B组吞咽过程中24小时(P=0.015)。两组之间在每个时间点的声音嘶哑的发生率和严重程度具有可比性(P>.05)。
    结论:术前吸入布地奈德联合静脉注射地塞米松可降低甲状腺切除术患者拔管后6、12和24小时POST的发生率和严重程度。此外,这种组合降低了术后24小时咳嗽的发生率.
    BACKGROUND: This randomized controlled trial aimed to evaluate the efficacy of preoperative inhaled budesonide combined with intravenous dexamethasone on postoperative sore throat (POST) after general anesthesia in patients who underwent thyroidectomy.
    METHODS: Patients who underwent elective thyroidectomy were randomly divided into the intravenous dexamethasone group (group A) and budesonide inhalation combined with intravenous dexamethasone group (group B). All patients underwent general anesthesia. The incidence and severity of POST, hoarseness, and cough at 1, 6, 12, and 24 hours after surgery were evaluated and compared between the 2 groups.
    RESULTS: There were 48 and 49 patients in groups A and B, respectively. The incidence of POST was significantly lower at 6, 12, and 24 hours in group B than that in group A (P < .05). In addition, group B had a significantly lower incidence of coughing at 24 hours (P = .047). Compared with group A, the severity of POST was significantly lower at 6 (P = .027), 12 (P = .004), and 24 (P = .005) hours at rest, and at 6 (P = .002), 12 (P = .038), and 24 (P = .015) hours during swallowing in group B. The incidence and severity of hoarseness were comparable at each time-point between the 2 groups (P > .05).
    CONCLUSIONS: Preoperative inhaled budesonide combined with intravenous dexamethasone reduced the incidence and severity of POST at 6, 12, and 24 hours after extubation compared with intravenous dexamethasone alone in patients who underwent thyroidectomy. Additionally, this combination decreased the incidence of postoperative coughing at 24 hours.
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  • 文章类型: Journal Article
    气管内插管是通常在全身麻醉下进行的气道管理程序。它与术后声音变化有关。声音嘶哑和声带损伤的发生率和原因没有很好的调查,尤其是在头颈部手术的短期麻醉和插管后。该研究的目的是确定头颈部手术中气管内麻醉后声音变化的原因。该研究将包括计划在气管插管长达3小时的全身麻醉下进行头颈部手术的患者。将有3组患者,如下:甲状腺手术,非甲状腺手术,对照组进行头颈部外手术。将在手术前后记录视频镜。进一步的诊断检查将包括语音状态;主观语音自我分析;4个时间点的感知和客观声学语音分析(术前,术后第2天,手术后2周和1个月)。气管内插管是一种安全的气道管理方法,尽管它可以暂时改变患者的语音质量。不知道有多少是麻醉的结果,患者的一般状况,或手术。预计这项审判将对这个问题有所了解。
    Endotracheal intubation is an airway management procedure commonly performed under general anesthesia. It is linked with postoperative voice changes. The incidence and reasons of hoarseness and vocal cord injury are not very well investigated, especially after short-term anesthesia and intubation in head and neck surgery. The aim of the study is to identify the causes of voice changes after short endotracheal anesthesia in head and neck surgery. The study will include patients scheduled for head and neck surgery under general anesthesia with endotracheal intubation up to 3 hours. There will be 3 groups of patients, as follows: thyroid surgery, non-thyroid surgery, and control group undergoing surgery outside head and neck. Videostroboscopy will be recorded before and after surgery. Further diagnostic workup will include voice status; subjective voice self-analysis; perceptive and objective acoustic voice analysis at 4 time points (preoperatively, postoperative day 2, 2 weeks and 1 month after surgery). Endotracheal intubation is a safe method of airway management although it can temporarily alter a patient\'s voice quality. It is not known how much of this is the result of anesthesia, general condition of the patient, or surgery. This trial is expected to shed some light on this issue.
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  • 文章类型: Case Reports
    浆细胞瘤是一种罕见的浆细胞发育不良,生长在骨骼或软组织如咽中。软组织浆细胞瘤罕见,据报道,上消化道负担较高,经常表现为声音嘶哑,吞咽困难,或者吞咽困难.由于它们的稀有性,髓外浆细胞瘤(EMPs)的预后因素未知,仍然缺乏优化管理的指导方针。然而,放射治疗和手术已被用于积极的结果.在这里,我们描述了一个有HIV病史的男性患者的咽组织浆细胞瘤的独特病例。患者完成了28次放射治疗,导致他的喉咙疼痛和声音嘶哑。鉴于患者的年龄和缺乏传统的头颈癌危险因素,他的声音嘶哑和吞咽困难被证明是一个诊断难题。虽然不常见,在头颈部肿瘤的鉴别诊断中,应考虑软组织浆细胞瘤。
    Plasmacytoma is a rare plasma cell dyscrasia that grows in bones or soft tissues such as the pharynx. Soft tissue plasmacytomas are rare, and a higher burden has been reported in the upper aero-digestive tract, often manifesting as hoarseness, dysphagia, or odynophagia. Due to their rarity, extramedullary plasmacytomas (EMPs) have unknown prognostic factors, and guidelines for optimal management are still lacking. However, radiation therapy and surgery have been used with positive outcomes. Herein, we describe a unique case of plasmacytoma of the pharyngeal tissue in a male patient with a history of HIV disease. The patient completed 28 sessions of radiation therapy, resulting in an improvement in his throat pain and hoarseness. Given the patient\'s age and lack of traditional risk factors for head and neck cancers, his hoarseness and odynophagia proved to be a diagnostic conundrum. Although infrequent, soft tissue plasmacytomas should be considered in the differential diagnosis of head and neck tumors.
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  • 文章类型: Randomized Controlled Trial
    背景:术后咽喉痛(POST)是一种令人不快的结果,可作为成人气管插管的结果。气管内导管(ETT)袖带的压力增加通常会导致局部粘膜损伤,导致喉咙痛。这项研究的目的是比较两种不同的ETT袖带压力监测系统与没有袖带压力监测成人POST的发生率和严重程度。
    方法:114名ASAI-III患者,18-65岁,和需要气管内插管的手术包括在这项研究中。患者被随机分为三组:对照组(C),袖带压力表(G),和自动袖带控制器(A)。C组术中不监测ETT袖带压力,但在G组和A组中使用袖带压力计和自动袖带控制器监测,分别。术后,在2、24和48小时评估患者POST的存在和严重程度,声音嘶哑和咳嗽.
    结果:111名患者完成了这项研究。术后48小时内G组40.5%的患者(n=37)(p=0.013)和A组23.7%的患者(n=38)(p<0.001)发生POST,C组为69.4%(n=36)。声音嘶哑没有显着差异,咳嗽,和吞咽困难。当比较A组和C组时,A组个体表现出较低的显著(≥2级)POST和声音嘶哑发生率(10.5%vs.41.7%,p=0.002;26.3%vs.58.3%,p=0.005)。手术后48小时内,患者组之间的严重咳嗽和吞咽困难的发生率没有显着差异。A组术后2、24h的POST评分均为0(0~0),2h时显著低于C组(1(0-2),p<0.001;24小时为1(0-1),p=0.001)。G组术后2h的POST评分为0(0-1.5),低于C组(P=0.024)。A组声音嘶哑程度0分(0~2分)优于C组(2分(0~2分),术后2小时p=0.006)。
    结论:结论:这项研究的结果表明,可以通过使用袖带压力表方法或自动袖带控制器方法来减少POST的发生。自动袖带控制器监测可以潜在地降低POST和声音嘶哑的严重性。
    背景:中国临床试验注册中心,标识符:ChiCTR2100054089,日期:08/12/2021.
    BACKGROUND: Postoperative sore throat (POST) is an unpleasant outcome that can occur as a result of tracheal intubation in adults. Increased pressure from the endotracheal tube (ETT) cuff often leads to local mucosal injury, resulting in sore throat. The purpose of this study was to compare the effect of two different ETT cuff pressure monitoring systems vs. no cuff pressure monitoring on the incidence and severity of POST in adults.
    METHODS: One hundred and fourteen ASA I-III patients of either gender, aged 18-65 years, and undergoing surgery requiring endotracheal intubation were included in this study. Patients were randomized into three groups: control (C), cuff pressure gauge (G), and automated cuff controller (A). The ETT cuff pressure was not monitored intraoperatively in group C but was monitored using a cuff pressure gauge and an automated cuff controller in groups G and A, respectively. Postoperatively, patients were assessed at 2, 24, and 48 h for the presence and severity of POST, hoarseness and cough.
    RESULTS: One hundred and eleven patients completed the study. POST occurred in 40.5% of the patients in group G (n = 37) (p = 0.013) and 23.7% of the patients in group A (n = 38) (p < 0.001) within 48 h after surgery, compared to 69.4% in group C (n = 36). There were no significant differences in hoarseness, coughing, and dysphagia across the groups at any time. When comparing groups A and C, individuals in group A exhibited a lower occurrence of significant (grade ≥ 2) POST and hoarseness (10.5% vs. 41.7%, p = 0.002; 26.3% vs. 58.3%, p = 0.005). The incidence of significant cough and dysphagia did not differ substantially across the patient groups within 48 h after surgery. POST scores in group A at 2, 24 h postoperatively were both 0 (0-0), which was significantly lower than those in group C (1 (0-2) at 2 h, p < 0.001 ; 1 (0-1) at 24 h, p = 0.001). POST in group G at 2 h postoperatively was graded as 0 (0-1.5) which was milder than group C (P = 0.024). The severity of hoarseness in group A with scores of 0 (0-2) was superior to that in group C (2 (0-2), p = 0.006) at 2 h postoperatively.
    CONCLUSIONS: In conclusion, the findings of this study indicated that the occurrence of POST can be reduced by using either the cuff pressure gauge approach or the automated cuff controller method. The automated cuff controller monitoring can potentially decrease the severity of POST and hoarseness.
    BACKGROUND: Chinese Clinical Trial Registry, identifier: ChiCTR2100054089, Date: 08/12/2021.
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  • 文章类型: Journal Article
    背景技术语音障碍(VD)对教师的职业和个人生活带来了重大挑战。教学需要广泛使用声音,使教师特别容易受到声乐健康问题的影响。VD会阻碍教育质量。目的本研究旨在全面探讨,相关因素,VD对教师的影响及其对VD的健康寻求行为。方法在塔伊夫市进行了横断面观察研究,沙特阿拉伯王国(KSA)2023年11月至12月。数据是通过涵盖人口统计学变量的问卷收集的,职业因素,语音相关症状,相关的健康状况,以及VD的影响。使用SPSSStatistics版本26(IBMCorp.2019年发布。IBMSPSSStatisticsforWindows,版本26.0。Armonk,纽约:IBM公司),和卡方检验用于评估关联。结果该研究涉及568名教师,61.8%的患者患有VD。这项研究确定了VD和人口统计学特征之间的显著关联,习惯,和教学相关变量。年龄,性别,教学主体,班级大小,每周的教学负荷与VD的患病率相关。声音嘶哑,喉咙疼痛,和咽喉干燥是VD教师中普遍存在的症状。VD对教师的影响是显而易见的,相当比例的人报告工作缺勤(28.7%),甚至考虑因语音问题退休(6.3%)。结论这项研究为塔伊夫地区的教师提供了对VD的细致理解,强调人口统计学的复杂相互作用,症状,和行为因素。调查结果强调了有针对性的干预措施的必要性,包括提高认识运动,预防策略,和简化的医疗服务,以解决不同子群教师面临的独特挑战。未来的研究应进一步探索纵向轨迹和客观措施,以增强我们对教育环境中VD的理解。
    Background Voice disorders (VD) pose significant challenges for teachers as they impact their professional and personal lives. Teaching requires extensive use of the voice, making teachers particularly susceptible to vocal health issues. VD can hinder the quality of education. Objectives This study aimed to comprehensively explore the prevalence, associated factors, and impact of VD among teachers and their health-seeking behavior regarding VD. Methodology A cross-sectional observational study was conducted in Taif City, Kingdom of Saudi Arabia (KSA), between November and December 2023. The data were collected through a questionnaire covering demographic variables, occupational factors, voice-related symptoms, associated health conditions, and the impact of VD. The statistical analysis was performed using SPSS Statistics version 26 (IBM Corp. Released 2019. IBM SPSS Statistics for Windows, Version 26.0. Armonk, NY: IBM Corp.), and chi-squared tests were used to assess associations. Results The study involved 568 teachers, 61.8% of whom had VD. The study identified significant associations between VD and demographic characteristics, habits, and teaching-related variables. Age, gender, teaching subject, class size, and weekly teaching load were associated with the prevalence of VD. Hoarseness, throat pain, and throat dryness were prevalent symptoms among teachers with VD. The impact of VD on teachers was evident, with a considerable proportion reporting work absenteeism (28.7%) and even contemplating retirement due to voice problems (6.3%). Conclusion This study offers a nuanced understanding of VD among teachers in the Taif region, emphasizing the complex interplay of demographic, symptomatic, and behavioral factors. The findings underscore the need for targeted interventions, including awareness campaigns, preventive strategies, and streamlined healthcare access, to address the unique challenges that different subgroups of teachers face. Future research should further explore longitudinal trajectories and objective measures to enhance our understanding of VD in educational settings.
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  • 文章类型: Case Reports
    喉真菌病,在具有系统免疫能力的个体中经常被忽视的情况,需要提高临床警惕性以进行准确诊断。该疾病模仿其他喉部疾病的症状,如胃食管反流,肉芽肿病,角化病,和声门恶性肿瘤,风险因素包括长期使用抗生素,吸入类固醇,和吸烟。临床上,它表现出各种症状,包括声音嘶哑,偶尔疼痛,吞咽困难,和吞咽困难.诊断包括观察角化过度,特别是当上皮内嗜中性粒细胞存在时,通过专门的染色提示进一步研究真菌元素。有效的管理包括延长全身抗真菌治疗和消除诱发因素以防止复发或治疗失败。尽管它有可能模仿一系列喉部疾病,喉真菌病仍然是一个较少考虑的鉴别诊断。一般人群中风险因素的共性加剧了这一点,包括长期使用抗生素,吸入类固醇治疗,和吸烟习惯,这可能会使个体易患喉部真菌感染。此外,高度怀疑和专业诊断技术的必要性,例如通过活检和真菌元素的专门染色鉴定上皮内嗜中性粒细胞过度角化,强调了诊断这种情况的复杂性。记录这个病例报告的理由是多方面的,主要集中在以下事实:喉真菌病在免疫功能正常的患者中很少见,导致系统性免疫功能正常的个体对喉真菌病的认识不足,以及它所带来的诊断挑战。此外,该文件旨在强调对综合治疗方法的迫切需要,包括长期的全身抗真菌治疗以及识别和消除诱发因素,确保有效管理并防止复发。
    Laryngeal mycosis, a condition often overlooked in systemically immunocompetent individuals, requires heightened clinical vigilance for accurate diagnosis. The disease mimics symptoms of other laryngeal conditions such as gastroesophageal reflux, granulomatous disease, keratosis, and glottic malignancies, with risk factors including prolonged use of antibiotics, inhaled steroids, and smoking. Clinically, it presents with variable symptoms including hoarseness, and occasionally pain, dysphagia, and odynophagia. Diagnosis involves the observation of hyperkeratosis, notably when intraepithelial neutrophils are present, prompting further investigation for fungal elements through specialized staining. Effective management encompasses prolonged systemic antifungal treatment and the elimination of predisposing factors to prevent recurrence or treatment failure. Despite its potential to mimic a range of laryngeal diseases, laryngeal mycosis remains a less considered differential diagnosis. This is compounded by the commonality of risk factors in the general population, including prolonged antibiotic use, inhaled steroid therapy, and smoking habits, which may predispose individuals to fungal infections of the larynx. Furthermore, the necessity for a high index of suspicion and specialized diagnostic techniques, such as the identification of hyperkeratosis with intraepithelial neutrophils through biopsy and specialized staining for fungal elements, underscores the complexity of diagnosing this condition. The rationale for documenting this case report is multifaceted, primarily focusing on the fact that laryngeal mycosis is rare among immunocompetent patients leading to under-recognition of laryngeal mycosis in systemically immunocompetent individuals and the diagnostic challenges it presents. Additionally, the documentation seeks to emphasize the critical need for comprehensive treatment approaches, including prolonged systemic antifungal therapy and the identification and elimination of predisposing factors, to ensure effective management and prevent recurrence.
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  • 文章类型: Journal Article
    本研究旨在探讨原发性甲状腺鳞状细胞癌(PSCCT)和继发性SCCT(SSCCT)的临床超声特征,并评估细针穿刺(FNA)推荐SCCT的准确性与美国放射学学会甲状腺成像和报告数据系统(ACR-TIRADS)和中国TIRADS(C-TIRADS)。
    我们检索了26例SCCT患者(11例PSCCT,15SSCCT)来自我们医院的病理数据库(5,718例甲状腺恶性肿瘤患者),超过23年。回顾性分析26例27例SCCT患者的病历及超声资料,每个SCCT病灶根据两个TIRADS进行分类。
    对于26名患者(21名男性,5名女性),年龄范围为42-81岁,快速扩大的甲状腺/颈部结节(18/26,69.2%),吞咽困难(7/26,26.9%),声音嘶哑(6/26,23.1%),呼吸困难(5/26,19.6%),咳嗽(4/26,15.4%),颈部疼痛(2/26,7.7%),B症状(2/26,7.7%),和痰中的血液(1/26,3.8%)在诊断时出现。超声检查发现5例无症状患者(5/26,19.2%)。声音嘶哑在PSCCT中(5/11,45.5%)比SSCCT中(1/15,6.7%)更常见(P=0.032)。对于平均尺寸为3.7±1.3cm的27个SCCT,超声特征由固体(25/27,92.6%)或几乎完全固体组成(2/27,7.4%)组成,低回声(17/27,63%)和极低回声回声(10/27,37%),不规则/分叶状边缘伴甲状腺外延伸(27/27,100%),高的比宽的形状(13/27,48.1%),点状回声灶(6/27,22.2%),高血管(23/27,85.2%)和累及颈部淋巴(13/26,50.0%)。两个TIRADS共评估了27个SCCT为高恶性危险分层(≥TR4和4B),推荐的FNA为96.3-100%(26/27,27/27)。病理上,超过一半的PSCCT(7/12,58.3%)和四分之一的SSCCT(4/15,26.7%)分化差,而在5个PSCCT和11个SSCCT中观察到中度和高度分化的等级(P=0.007)。13例(50.0%)患者行根治性手术5例(5/13,38.5%)。
    SCCT是一种极其罕见且侵袭性的恶性肿瘤,以男性为主。PSCCT和SSCCT具有相似的临床和超声特征,除了肿瘤分化和声音嘶哑症状。SCCT在ACR-TIRADS和C-TIRADS中显示出高恶性危险分层,具有较高的FNA推荐率。
    UNASSIGNED: This study aimed to investigate the clinico-ultrasound features of primary squamous cell carcinoma of the thyroid (PSCCT) and secondary SCCT (SSCCT) and evaluate the accuracy of fine needle aspiration (FNA) recommendation for SCCT with American College of Radiology-Thyroid Imaging and Reporting Data System (ACR-TIRADS) and Chinese-TIRADS (C-TIRADS).
    UNASSIGNED: We retrieved 26 SCCT patients (11 PSCCT, 15 SSCCT) from our hospital\'s pathology database (5,718 patients with thyroid malignancy) over 23 years. Medical records and ultrasound data of the 26 patients with 27 SCCTs were analyzed retrospectively, and each SCCT focus was categorized based on the two TIRADSs.
    UNASSIGNED: For 26 patients (21 males, 5 females) with an age range of 42-81 years, rapidly enlarging thyroid/neck nodules (18/26, 69.2%), dysphagia (7/26, 26.9%), hoarseness (6/26, 23.1%), dyspnea (5/26, 19.6%), cough (4/26, 15.4%), neck pain (2/26, 7.7%), B symptoms (2/26, 7.7%), and blood in sputum (1/26, 3.8%) were presented at diagnosis. Five asymptomatic patients (5/26, 19.2%) were detected by ultrasound. Hoarseness was more common in PSCCT (5/11, 45.5%) than in SSCCT (1/15, 6.7%) (P=0.032). For 27 SCCTs with a mean size of 3.7 ± 1.3 cm, the ultrasound features consisted of solid (25/27, 92.6%) or almost completely solid composition (2/27, 7.4%), hypoechoic (17/27, 63%) and very hypoechoic echogenicity (10/27, 37%), irregular/lobulated margin with extra-thyroidal extension (27/27, 100%), taller-than-wide shape (13/27, 48.1%), punctate echogenic foci (6/27, 22.2%), hypervascularity (23/27, 85.2%) and involved neck lymph (13/26, 50.0%). A total of 27 SCCTs were evaluated as high malignancy risk stratification (≥TR4 and 4B) by the two TIRADSs and recommended FNA in 96.3-100% (26/27, 27/27). Pathologically, more than half of PSCCTs (7/12, 58.3%) and a quarter of SSCCTs (4/15, 26.7%) were poorly differentiated, while moderately and well-differentiated grades were observed in 5 PSCCTs and 11 SSCCTs (P=0.007). Thirteen patients (50.0%) underwent surgery with radical operation in 5 cases (5/13, 38.5%).
    UNASSIGNED: SCCT is an extremely rare and aggressive malignancy with a male predominance. PSCCT and SSCCT had similar clinical and ultrasound features except for tumor differentiation and the symptom of hoarseness. SCCT showed a high malignancy risk stratification in ACR-TIRADS and C-TIRADS, with a high rate of FNA recommendation.
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  • 文章类型: Journal Article
    这项研究的主要目的是找出声音嘶哑的病因,并根据年龄等社会人口统计学特征分析声音嘶哑的人。性别,职业和社会经济地位。次要目的是找出声音嘶哑的诱发因素,并了解声音嘶哑的良性和恶性原因之间的关系。这项研究对178名年龄在18岁以上的患者进行了为期一年半的研究,这些患者在耳鼻咽喉科表现出持续超过2周的声音嘶哑。在获得书面知情同意书后,我们使用结构化形式采集病史,并进行适当的临床检查,包括间接喉镜检查.在困难的情况下进行鼻咽喉镜检查。在178名声音嘶哑患者的样本中,159例患者有结构性病变,19例患者有运动障碍。在结构性病变中,86例患者是由于恶性肿瘤,64由于非肿瘤原因,9例是由于癌前原因。声音嘶哑最常见的恶性原因是恶性声门,有男性偏爱。吸烟和酗酒是主要的诱发因素。最常见的非肿瘤原因是声带小结和声带息肉。主要的诱发因素是声音滥用,主要见于女性。发现声带麻痹是最常见的运动障碍。声音嘶哑作为一种症状,如果轻视会导致严重的后果。因此,重要的是避免吸烟等诱发因素,酗酒,也教育人们正确使用声音。
    The primary objective of the study was to find out the aetiology of hoarseness and analyse people with hoarseness based on socio-demographic profile like age, gender, occupation and socio-economic status. Secondary objective was to find out the predisposing factors of hoarseness and to see their association between benign and malignant causes of hoarseness. The study was conducted for a period of one and half years in 178 patients who were above the age of 18 years of age and presented with hoarseness lasting for more than 2 weeks to the Department of Otorhinolaryngology. After obtaining a written informed consent, history was taken using a structured proforma and a proper clinical examination was done including indirect laryngoscopy. Nasopharyngolarygoscopy was done where indirect laryngoscopy was difficult. In a sample of 178 patients with hoarseness, 159 patients had structural lesions and 19 patients had movement disorders. Of the structural lesions, 86 patients were due to malignancy, 64 due to non-neoplastic causes, and 9 were due to premalignant causes. The most common malignant cause for hoarseness was Malignancy glottis, which had a male predilection. Smoking and alcoholism were found to be the main predisposing factors. The most common non neoplastic cause were vocal cord nodule and vocal cord polyp. The main predisposing factor was vocal abuse and was seen mostly in females. Vocal cord palsy was found to be the most common movement disorder. Hoarseness as a symptom if taken lightly can lead to serious consequences. Therefore it is important to avoid predisposing factors like smoking, alcoholism and also to educate the people regarding the proper use of voice.
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