■胎盘感染很常见,特别是在发展中国家,在怀孕人群中进行有限的筛查以寻找感染因子。我们的目的是确定弓形虫抗体的临床和流行病学特征和血清感染,细小病毒B19,梅毒螺旋体,以及在兰巴耶克的Motupe健康中心就诊的孕妇中的艾滋病毒,秘鲁2018年7月至8月。
■对179名接受标准化问卷调查的孕妇进行了描述性横断面研究。ELISA用于确定弓形虫和细小病毒B19的抗体。梅毒和HIV的检测采用免疫层析法,虽然乙型肝炎的检测是使用FTA-ABS和免疫荧光进行的,分别。
■在179名孕妇中,筛查孕妇中常规包括的梅毒和艾滋病毒感染的血清感染率为2.2%和0.6%,分别。弓形虫病血清感染率为25.1%,而IgM抗细小病毒B19占40.8%,揭示孕妇在研究时患有活动性感染。
弓形虫病的血清感染水平揭示了参与研究的孕妇暴露的风险。细小病毒B19的高血清感染可以解释Motupe报道的自然流产病例和新生儿贫血水平。Lambayeque,秘鲁。然而,未来的因果关系研究对于确定这些发现的意义是必要的。
UNASSIGNED: Transplacental infections are frequent, especially in developing countries, where limited screening is performed to find infectious agents in the pregnant population. We aim to determine the clinical and epidemiological characteristics and seroinfection of antibodies against Toxoplasma, parvovirus B19, T. pallidum, and HIV in pregnant women who attended the Motupe Health Center in Lambayeque, Peru during July-August 2018.
UNASSIGNED: A descriptive cross-sectional study was conducted in 179 pregnant women interviewed with a standardized questionnaire. ELISA was used to determine antibodies to Toxoplasma and parvovirus B19. The detection of syphilis and HIV was conducted using immunochromatography, while the detection of hepatitis B was conducted using FTA-ABS and immunofluorescence, respectively.
UNASSIGNED: Of 179 pregnant women, syphilis and HIV infections routinely included in the screening of pregnant women presented a seroinfection of 2.2 and 0.6%, respectively. Toxoplasmosis seroinfection was 25.1%, while IgM antiparvovirus B19 was 40.8%, revealing that pregnant women had an active infection at the time of study.
UNASSIGNED: The level of seroinfection of toxoplasmosis reveals the risk to which pregnant women who participated in the study are exposed. The high seroinfection of parvovirus B19 could explain the cases of spontaneous abortion and levels of anemia in newborn that have been reported in Motupe, Lambayeque, Peru. However, future causality studies are necessary to determine the significance of these findings.