■弓形虫(T.gondii)是食用动物中重要的原生动物病原体。尽管弓形虫感染对公众健康构成威胁,对中国大陆食用动物血清阳性率和趋势的了解有限。本研究旨在评估猪弓形虫感染的血清阳性率,绵羊,山羊,鸡,和2010年至2023年中国大陆牛。
■我们搜索了2010年至2023年之间发表的横断面研究,这些研究报告了来自PubMed等数据库的食用动物中弓形虫的患病率,Embase,WebofScience,中国生物医学光盘(CBM),中国国家知识基础设施(CNKI),万方数据,和中国科技期刊数据库(CQVIP)。我们进行了亚组分析,以探讨不同因素对弓形虫血清阳性率的影响。用随机效应模型计算弓形虫血清阳性率的汇总估计值。
■对涉及211985年动物的184项研究的分析显示,弓形虫的总体血清阳性率为15.3%(95%CI:13.1-17.8)。尽管从2010年到2023年,中国大陆食用动物的血清阳性率相对稳定,但在不同动物类型和地区之间观察到了显着差异(P<0.01)。随着地理分布的变化。样品类型,检测方法,动物年龄,流产史被确定为弓形虫血清阳性率的关键危险因素。
■该研究对2010年至2023年中国大陆食用动物弓形虫血清阳性率进行了荟萃分析,并确定了关键危险因素。这些发现促进了我们对弓形虫感染动力学的理解,为制定控制策略和指导公共卫生政策提供重要见解。
UNASSIGNED: Toxoplasma gondii (T. gondii) is a significant protozoan pathogen among food animals. Despite the threat to public health by T. gondii infections, there\'s limited understanding of its seroprevalence and trends in food animals across mainland
China. This study aimed to estimate the seroprevalence of T. gondii infections among swine, sheep, goats, chickens, and cattle in mainland
China from 2010 to 2023.
UNASSIGNED: We searched cross-sectional studies published between 2010 and 2023 that reported the prevalence of T. gondii in food animals from databases including PubMed, Embase, Web of Science,
China Biology Medicine Disc (CBM),
China National Knowledge Infrastructure (CNKI), Wanfang data, and the
China Science and Technology Journal Database (CQVIP). We performed subgroup analyses to explore the impact of different factors on the seroprevalence of T. gondii. Pooled estimates of T. gondii seroprevalence were calculated with a random-effects model.
UNASSIGNED: An analysis of 184 studies involving 211985 animals revealed a T. gondii overall seroprevalence of 15.3% (95% CI: 13.1-17.8). Although the seroprevalence of food animals across mainland
China was relatively stable from 2010 to 2023, notable variations were observed across different animal types and regions (P < 0.01), along with changes in geographical distribution. Sample type, detection method, animal age, and history of abortion were identified as key risk factors for T. gondii seroprevalence.
UNASSIGNED: The study conducted a meta-analysis on the seroprevalence of T. gondii in mainland China\'s Food Animals from 2010 to 2023, and identified key risk factors. These findings advance our understanding of T. gondii infection dynamics, offering critical insights for developing control strategies and guiding public health policies.