■确定心血管疾病(CVD)的危险因素对于有效预防和管理至关重要。虽然经典的CVD危险因素已被广泛研究,关于打鼾和心血管疾病风险之间的关系的研究很少,特别是在性别差异的背景下。
■这项研究利用了2015年至2020年进行的国家健康与营养调查(NHANES)的数据。最初根据打鼾的严重程度或打鼾的存在对参与者进行分类。在打鼾群体中,他们进一步按性别分类。采用多因素logistic回归进行分析。
■我们的研究包括12,681名18岁或以上的参与者。与非打鼾组相比,中度打鼾组的个体具有较高的比值比(OR)1.418(95%CI1.083至1.857,p=0.011),而重度打鼾组的OR值较高,为1.882(95%CI1.468至2.409,p<0.001)。在打鼾组中,进一步按性别分类:男性4527人,女性4131人.重要的是,与女性相比,男性患者房颤的OR值较高(4.945,95%CI1.187~20.598,p=0.028).此外,与女性相比,男性患者的冠心病OR值较高(2.002,95%CI1.152~3.479,p=0.014).
■性别在打鼾与CVD风险之间的关系中起着重要作用。与女性相比,打鼾的男性患CVD的风险更高。特别是,与女性打鼾者相比,男性打鼾者发生心房纤颤的可能性几乎是女性的五倍,发生冠状动脉疾病的可能性大约是女性的两倍。建议医疗保健提供者和公共卫生官员优先考虑表现出打鼾症状的男性个体的心血管风险评估。
UNASSIGNED: Identifying risk factors for cardiovascular disease (CVD) is critical for effective prevention and management. While classic CVD risk factors have been extensively studied, there is a scarcity of research on the association between snoring and CVD risk, particularly in the context of sex differences.
UNASSIGNED: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) conducted between 2015 and 2020. Participants were initially categorized based on the severity of snoring or the presence of snoring.Within the snoring group, they were further classified by sex. Analysis was carried out using multivariate logistic regression.
UNASSIGNED: Our study included 12,681 participants aged 18 years or older. When compared to the non-snoring group, individuals in the moderate snoring group had a higher odds ratio (OR) of 1.418 (95% CI 1.083 to 1.857, p = 0.011), while those in the severe snoring group had a higher OR of 1.882 (95% CI 1.468 to 2.409, p < 0.001). In the snoring group, individuals were further categorized by gender: 4527 males and 4131 females. Importantly, male patients showed a higher OR for atrial fibrillation (4.945, 95% CI 1.187 to 20.598, p = 0.028) compared to females. Additionally, male patients had a higher OR for coronary heart disease (2.002, 95% CI 1.152 to 3.479, p = 0.014) compared to females.
UNASSIGNED: Sex plays a significant role in the relationship between snoring and CVD risk. Males with snoring have a higher risk of developing CVD compared to females. In particular, male snorers are nearly five times more likely to develop atrial fibrillation and about twice as likely to experience coronary artery disease in comparison to female snorers. It is recommended that healthcare providers and public health officials prioritize cardiovascular risk assessments for male individuals who exhibit symptoms of snoring.