flow

流量
  • 文章类型: Journal Article
    这项研究调查了430名中国大学生对艺术活动的参与以及从这些活动中获得的心理益处。该研究区分了各种类型的艺术参与和参与方式,并研究了四种潜在的积极心理结果。研究结果表明,(1)表演艺术中的创造性参与,\'流\',和审美情感;(2)对视觉艺术和审美情感的消费参与;(3)对文学艺术和自我认同的创造性参与。整体艺术参与与繁荣有着显着的正相关关系。路径分析表明,流动体验和审美情感在整体艺术参与影响繁荣的机制中起着中介作用,具有从流动经验到自我认同的连锁中介效应。这项研究证实,艺术参与是个人繁荣的有效途径,对艺术的更多样化和深刻的参与可以带来持续和广泛的幸福。
    This study examined 430 Chinese college students\' engagement in arts activities and the psychological benefits derived from such activities. The research differentiated between various types of arts participation and ways of involvement and examined four potential positive psychological outcomes. The findings revealed correlations between (1) creative participation in the performing arts, \'flow\', and aesthetic emotions; (2) consumptive participation in the visual arts and aesthetic emotions; and (3) creative participation in the literary arts and ego identity. Holistic arts participation demonstrated a significantly positive relationship with flourishing. A path analysis showed that flow experience and aesthetic emotions served as mediators in the mechanism through which holistic arts participation affected flourishing, with a chained mediation effect from flow experience to ego identity. This study confirms that arts participation is an effective pathway for individual flourishing and that more diverse and profound engagement in the arts can lead to sustained and widespread happiness.
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  • 文章类型: Journal Article
    衬底上单个纳米颗粒的光学诱导形状转变已经显示出对于单颗粒器件制造和芯片上集成的简单性和规则性的益处。然而,大多数现有的策略是基于湿化学生长和蚀刻,这可能导致表面污染,局部选择性和设备兼容性有限。经由光热效应的形状变形可以克服这些问题,但是很大程度上由于熔融液滴的高表面张力而具有有限的通用性和可调性。在这里,我们显示金纳米粒子(AuNPs)可以在连续波激光(446nm)的照射下急剧转变为纳米板。我们发现,在光热泳力的驱动下,熔融Au下方的介电薄膜对于将NP变形为多面纳米板至关重要,这足以抵消熔滴的表面张力。实验证据和模拟都支持这种薄膜辅助光热变形机制,这是局部选择性的,通常适用于不同形状的AuNP。它为基于单板的设备应用提供了一个简单而强大的策略。
    Optical-induced shape transformation of single nanoparticles on substrates has shown benefits of simplicity and regularity for single-particle device fabrication and on-chip integration. However, most of the existing strategies are based on wet chemical growth and etching, which could lead to surface contamination with limited local selectivity and device compatibility. Shape deformation via the photothermal effect can overcome these issues but has limited versatility and tunability largely due to the high surface tension of the molten droplet. Here we show gold nanoparticles (Au NPs) can drastically transform into nanoplates under the irradiation of a continuous wave laser (446 nm). We reveal the dielectric thin film underneath the molten Au is critical in deforming the NP into faceted nanoplate under the drive of photothermophoretic forces, which is sufficient to counteract the surface tension of the molten droplet. Both experimental evidence and simulations support this thin-film-assisted photothermal deformation mechanism, which is local selective and generally applicable to differently shaped Au NPs. It provides a facile and robust strategy for single-plate-based device applications.
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  • 文章类型: Journal Article
    探讨消费者在直播中冲动性购买行为的影响因素,基于刺激-有机体-反应框架,我们通过查阅文献,构建了流媒体如何影响消费者冲动购买行为的模型。通过问卷收集数据,并利用结构方程模型进行了实证研究,探讨了拖缆影响消费者冲动性购买行为的机制。结果表明,流光特征(个人魅力,专业性)和流媒体性能(交互性,娱乐)通过影响消费者的信任和流量体验来影响消费者的冲动性购买行为。实证结果具有重要的理论和现实意义。
    To explore the influencing factors of consumers\' impulsive purchase behavior in live streaming, based on the Stimulus-Organism-Response framework, we construct the model of how streamers influence consumers\' impulsive purchase behavior by consulting literature. Collected data by means of a questionnaire, and made an empirical study by using the structural equation model to explore the mechanism of streamer affecting consumers\' impulsive purchase behavior. The results show that streamer characteristics (personal charisma, professionalism) and streamer performance (interactivity, entertainment) affect consumers\' impulsive purchase behavior by affecting consumers\' trust and flow experience. The empirical results have important theoretical and practical significance.
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  • 文章类型: Journal Article
    背景:肺癌(LC)发病率在全球范围内正在上升,并被反映为癌症相关死亡的主要原因。肺癌导致多阶段癌变,遗传和表观遗传变化逐渐增加。
    目的:血根碱(sang)通过刺激活性氧(ROS)介导LCC系的抗癌作用,阻碍Bcl2,并增强Bax和其他凋亡相关蛋白Caspase-3,-9和-PARP,随后抑制LC的入侵和迁移。
    目的:本研究旨在研究Sang在人LC细胞(LCC)H522和H1299中的凋亡率和机制。
    方法:MTT法测定IC50,细胞形态,进行集落形成测定以显示血根碱对LC细胞系的作用。此外,进行划痕测定和transwell测定以检查迁移。进行Western印迹和qPCR以显示其对靶向蛋白质和基因的影响。进行ELISA以显示血根碱处理后的VEGF作用。进行免疫荧光以检查目标蛋白的位置。
    结果:Sang以时间和剂量依赖性方式显着抑制LCC系的生长。流式细胞术检查和膜联蛋白-V标记确定Sang增加了凋亡细胞百分比。用Sang处理的H522和H1299LCC细胞系表现出独特的凋亡特征,包括形态变化和DNA片段化。
    结论:Sang在LCC细胞系中具有抗癌潜力,可诱导细胞凋亡并阻止LCC的侵袭和迁移。正在成为肺癌治疗中一种有前途的抗癌天然药物。
    BACKGROUND: Lung cancer (LC) incidence is rising globally and is reflected as a leading cause of cancer-associated deaths. Lung cancer leads to multistage carcinogenesis with gradually increasing genetic and epigenetic changes.
    OBJECTIVE: Sanguinarine (sang) mediated the anticancer effect in LCC lines by involving the stimulation of reactive oxygen species (ROS), impeding Bcl2, and enhancing Bax and other apoptosis-associated protein Caspase-3, -9, and -PARP, subsequently inhibiting the LC invasion and migration.
    OBJECTIVE: This study was conducted to investigate the apoptotic rate and mechanism of Sang in human LC cells (LCC) H522 and H1299.
    METHODS: MTT assay to determine the IC50, cell morphology, and colony formation assay were carried out to show the sanguinarine effect on the LC cell line. Moreover, scratch assay and transwell assay were performed to check the migration. Western blotting and qPCR were done to show its effects on targeted proteins and genes. ELISA was performed to show the VEGF effect after Sanguinarine treatment. Immunofluorescence was done to check the interlocution of the targeted protein.
    RESULTS: Sang significantly inhibited the growth of LCC lines in both time- and dose-dependent fashions. Flow cytometry examination and Annexin-V labeling determined that Sang increased the apoptotic cell percentage. H522 and H1299 LCC lines treated with Sang showed distinctive characteristics of apoptosis, including morphological changes and DNA fragmentation.
    CONCLUSIONS: Sang exhibited anticancer potential in LCC lines and could induce apoptosis and impede the invasion and migration of LCC, emerging as a promising anticancer natural agent in lung cancer management.
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  • 文章类型: Journal Article
    这项研究探讨了不同类型的增强现实(AR)曼陀罗着色活动对大学生正念和流动的影响。
    共有76名大学生参加了这项研究,并根据他们的绘画技能分为两组:高技能组(n=38)和低技能组(n=38)。在AR技术的帮助下,两组受试者用结构化的曼陀罗进行了三个曼陀罗着色实验,免费曼陀罗和合作曼陀罗。实验程序中的测量评估包括在所有实验之前的预测试(时间0)和在三个曼陀罗着色活动之后的每个后测试(时间1、时间2和时间3)。测量两组的流量和挑战技能的平衡维度。
    ANOVA结果表明,单次30分钟的短期曼陀罗着色活动并未显着改善正念(f=2.339,p=0.074,η2=0.031),但显着改善了流量(f=11.918,p=<0.001,η2=0.139)。线性回归结果发现正念与流量的某些维度之间存在正相关关系(例如,专注于一项任务,明确的反馈,控制感,挑战——技能平衡,和自动体验)。还发现正念与流的自我意识成分的丧失呈负相关。我们还发现,自由曼陀罗对于低技能组的受试者来说非常具有挑战性,而合作社曼陀罗的团队合作帮助他们克服困难,应对挑战。
    通过简短的AR曼陀罗着色练习,可以快速有效地改善流量。本研究的贡献在于为进一步探索曼陀罗着色如何改善受试者的心理状态、促进积极心理机制的完善和发展提供启示和借鉴。
    UNASSIGNED: This study explores the effects of different types of augmented reality (AR) mandala coloring activities on mindfulness and flow in college students.
    UNASSIGNED: A total of 76 college students participated in the study and were divided into two groups based on their drawing skills: the high-skilled group (n = 38) and the low-skilled group (n = 38). With the help of AR technology, two groups of subjects carried out three mandala coloring experiments with structured mandala, free mandala and cooperative mandala in order. The measurement evaluation in the experimental program included a pre-test before all the experiments (Time 0) and each post-test after three mandala coloring activities (Time 1, Time 2 and Time 3). The balance dimensions of flow and challenge skills of the two groups were measured.
    UNASSIGNED: ANOVA results showed that a single 30-min short-term datura coloring activity did not significantly improve mindfulness (f = 2.339, p = 0.074, η2 = 0.031), but did significantly improve flow (f = 11.918, p = < 0.001, η2 = 0.139). Linear regression results found positive correlations between mindfulness and certain dimensions of flow (e.g., focus on a task, unambiguous feedback, sense of control, challenge -- skill balance, and automatic experience). Mindfulness was also found to be negatively correlated with the loss of the self-conscious component of flow. We also found that the free mandala was quite challenging for subjects in the low-skill group, while the teamwork in the cooperative mandala helped them overcome difficulties and cope with challenges.
    UNASSIGNED: Flow can be quickly and effectively improved through short AR mandala coloring exercises. The contribution of this study is to provide inspiration and reference for further exploring how AR mandola coloring can improve subjects\' mental state and promote the perfection and development of positive psychological mechanism.
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  • 文章类型: Journal Article
    针对双向非定常液体流量测量模型开发了电动洗胃机的标定方法,研制了医用电动洗胃机的检测装置,哪个流量值可以追溯到质量和时间。实验结果表明,该检测装置的流量测量范围为(50~3000)mL/min,压力测量范围为(-60~90)kPa,采用主动式活塞式流量标准装置验证的检测装置的计量性能能够满足医用电动洗胃机关键参数的可追溯性要求。
    The calibration method of the electric gastric lavage machine was developed for the two-way unsteady liquid flow measurement modeland the detection device of the medical electric gastric lavage machine was developed , which flow value can be traced to the quality and time. The experimental results showed that the flow measurement range of the detection device was (50∼3000) mL/min, and the pressure measurement range was (-60∼90) kPa, and the metrological performance of the detection device verified using an active piston type flow standard device can meet the traceability requirements of the key parameters of the medical electric gastric lavage machine.
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  • 文章类型: Journal Article
    目的:开发一种部分可解释的神经网络,用于联合抑制非相位循环bSSFP电影成像中的条带和流动伪影。
    方法:提出了由体素识别(VI)子网络和伪影抑制(AS)子网络组成的双级神经网络。VI子网络提供工件的识别,它引导伪影抑制并提高可解释性。AS子网络减少了条带和流伪影。来自28名健康受试者的12个频率偏移的短轴电影图像用于训练和测试双级网络。另外77例患者被回顾性纳入以评估其临床普遍性。对于健康的受试者,通过与传统相位循环的比较,分析了伪影抑制性能。通过相关性分析对VI子网络提供的部分可解释性进行了分析。对使用不同序列参数和扫描仪获得的电影进行了通用性评估。对于患者来说,3名临床医师对网络的伪影抑制性能和部分可解释性进行了定性评估.通过左心室射血分数(LVEF)评估伪影抑制前后的心功能。
    结果:对于健康受试者,视觉检查和定量分析发现,所提出的网络大大减少了条带和流动伪影。与传统相位循环相比,所提出的网络改善了血流伪影评分(4.57±0.23vs3.40±0.38,P=0.002)和总体图像质量(4.33±0.22vs3.60±0.38,P=0.002).VI子网络很好地识别了原始电影中条带和流动伪影的位置,并与这些区域中信号强度的变化显着相关。成像参数或扫描仪的变化没有引起相对于基线数据集的整体图像质量的显著变化,表明了良好的概括性。对病人来说,定性分析显示条带伪影显著改善(4.01±0.50vs2.77±0.40,P<0.001),流动伪影(4.22±0.38vs2.97±0.57,P<0.001),相对于原始电影,图像质量(3.91±0.45vs2.60±0.43,P<0.001)。伪影抑制略微降低了LVEF(平均偏差=-1.25%,P=0.01)。
    结论:双阶段网络可同时减少bSSFP电影成像中的条带和流动伪影,具有部分可解释性,保留序列修改的需要。该方法可以容易地部署在临床环境中以识别伪影并提高电影图像质量。
    To develop a partially interpretable neural network for joint suppression of banding and flow artifacts in non-phase-cycled bSSFP cine imaging.
    A dual-stage neural network consisting of a voxel-identification (VI) sub-network and artifact-suppression (AS) sub-network is proposed. The VI sub-network provides identification of artifacts, which guides artifact suppression and improves interpretability. The AS sub-network reduces banding and flow artifacts. Short-axis cine images of 12 frequency offsets from 28 healthy subjects were used to train and test the dual-stage network. An additional 77 patients were retrospectively enrolled to evaluate its clinical generalizability. For healthy subjects, artifact suppression performance was analyzed by comparison with traditional phase cycling. The partial interpretability provided by the VI sub-network was analyzed via correlation analysis. Generalizability was evaluated for cine obtained with different sequence parameters and scanners. For patients, artifact suppression performance and partial interpretability of the network were qualitatively evaluated by 3 clinicians. Cardiac function before and after artifact suppression was assessed via left ventricular ejection fraction (LVEF).
    For the healthy subjects, visual inspection and quantitative analysis found a considerable reduction of banding and flow artifacts by the proposed network. Compared with traditional phase cycling, the proposed network improved flow artifact scores (4.57 ± 0.23 vs 3.40 ± 0.38, P = 0.002) and overall image quality (4.33 ± 0.22 vs 3.60 ± 0.38, P = 0.002). The VI sub-network well identified the location of banding and flow artifacts in the original movie and significantly correlated with the change of signal intensities in these regions. Changes of imaging parameters or the scanner did not cause a significant change of overall image quality relative to the baseline dataset, suggesting a good generalizability. For the patients, qualitative analysis showed a significant improvement of banding artifacts (4.01 ± 0.50 vs 2.77 ± 0.40, P < 0.001), flow artifacts (4.22 ± 0.38 vs 2.97 ± 0.57, P < 0.001), and image quality (3.91 ± 0.45 vs 2.60 ± 0.43, P < 0.001) relative to the original cine. The artifact suppression slightly reduced the LVEF (mean bias = -1.25%, P = 0.01).
    The dual-stage network simultaneously reduces banding and flow artifacts in bSSFP cine imaging with a partial interpretability, sparing the need for sequence modification. The method can be easily deployed in a clinical setting to identify artifacts and improve cine image quality.
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  • 文章类型: Journal Article
    在满足社会经济发展要求的同时,水坝是影响大型河流非生物和生物因素的物理屏障。这些改变的因素可以相互作用,并逐渐重塑当地的生态系统状态。重塑的状态可能会向下游扩散并大规模影响生态系统状态。然而,大型河流生态系统状态的传播范围和特征仍未得到充分研究。为了解决这个问题,研究了长江中替代微生物群状态及其对环境条件的响应,考虑替代稳定状态理论在解释生态系统状态响应方面的优势以及底栖微生物在指示生态系统状态方面的作用。在这项研究中,流量排放被确定为将底栖微生物群聚集为两种类型的主要水文因素,这两种微生物群是双稳态的,其特征是蓝细菌门的富集差异。潜在分析表明,将流量排放减少到阈值以下(即,流量排放<12,900m3/s)可能会将底栖微生物转移到底栖蓝细菌将成为优势物种的状态(微生物区系B)。在双稳态区域(即,12,900<流量排放<28,000m3/s),通过相对潜在深度计算和中性群落建模,发现生态韧性和确定性过程的贡献都很弱,这表明该区域易受其上游微生物群状态的影响,因此值得更多的科学关注,以防止不利状态向下游传播。此外,B州微生物区系的高反硝化潜力可能是低N:P比的原因,进一步有利于固氮蓝藻的优势。这项研究凭经验显示了替代微生物群状态对流动梯度的响应,并探讨了长江干流微生物群的分布和特征,因此,为大型河流的环境流量设计和水库调节提供见解。
    While satisfying the demands of social and economic development, dams act as physical barriers affecting both abiotic and biotic factors in large rivers. These altered factors can interact with each other and gradually reshape the local ecosystem state. The reshaped state may spread downstream and affect ecosystem states on a large scale. However, the spread extent and characteristics of ecosystem states along large rivers remain understudied. To address this problem, alternative microbiota states and their responses to environmental conditions in the Yangtze River were investigated, considering the preponderance of alternative stable states theory in explaining the response of ecosystem states as well as the role of benthic microorganisms in indicating ecosystem states. In this study, flow discharge was identified as the main hydrological factor that clustered benthic microbiota into two types, and these two microbiota types were bistable and characterized by differential enrichment of the Cyanobacteria phylum. Potential analysis demonstrated that reducing flow discharge beneath a threshold (i.e., flow discharge < 12,900 m3/s) could shift benthic microbiotas to a state where benthic cyanobacteria would become the dominant species (the Microbiota State B). In the bistable region (i.e., 12,900 < flow discharge < 28,000 m3/s), both the ecological resilience and the contribution of deterministic process were found weak by relative potential depth calculations and neutral community modeling, suggesting that this region is susceptible to the microbiota state of its upstream and thus deserves more scientific attention to prevent the unfavorable state from spreading downstream. In addition, high denitrification potential at sites of the Microbiota State B was likely responsible for the low N:P ratio, further benefiting the dominance of N-fixing cyanobacteria. This study empirically showed the response of alternative microbiota states to flow gradients, and explored the distribution and characteristics of the microbiota states along the mainstream of the Yangtze River, therefore providing insights into environmental flow design and reservoir regulation of large rivers.
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  • 文章类型: Journal Article
    使用基于球形视频的虚拟现实(SVVR)教材进行学习的学生能够获得更多的自我调节能力,探索性的,在虚拟环境中身临其境的体验。在艺术课程中使用SVVR教材可以呈现多样化和独特的教学效果,同时也导致了学生流动状态的出现。
    因此,通过美术课程教学实验,本研究调查了380名高中生,并使用结构方程模型分析了学生使用SVVR教材时流动状态的前因和结果。
    结果表明,在艺术课程中使用SVVR教材时,应该更多地关注学生流动状态的控制和远程呈现。
    只有当他们获得更好的流动体验时,他们才能对艺术课程内容具有更高的感知有用性和满意度,以及继续使用它的更强烈意图。研究结果可为SVVR教材在高中美术课程中的开发和使用提供参考。
    UNASSIGNED: Students who use spherical video-based virtual reality (SVVR) teaching materials for learning are able to gain more self-regulated, explorative, and immersive experiences in a virtual environment. Using SVVR teaching materials in art courses can present diverse and unique teaching effects, while also leading to the emergence of students\' flow states.
    UNASSIGNED: Therefore, through an art course teaching experiment, this study investigated 380 high school students and used structural equation modeling to analyze the antecedents and outcomes of students\' flow state in using SVVR teaching materials.
    UNASSIGNED: The results show that in using SVVR teaching materials in art courses, more attention should be paid to the control and telepresence in the antecedents of students\' flow state.
    UNASSIGNED: Only when they obtain better flow experiences can they have higher perceived usefulness and satisfaction with the content of the art course, as well as stronger intentions to continue using it. These results can provide a reference for the development and use of SVVR teaching materials in high school art courses.
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  • 文章类型: Journal Article
    HFNC装置的生理作用与温度和湿度密切相关。来自不同制造商的HFNC装置可具有不同的性能。目前尚不清楚不同HFNC装置的加湿性能是否存在差异以及差异程度。
    四个集成HFNC设备(AIRVO2,Fisher&PaykelHealthcare,奥克兰,新西兰;TNIsoftFlow50,TNIMedicalAG,维尔茨堡,德国;HUMID-BH,呼吸道护理,沈阳,中国;OH-70C,Micomme,湖南,中国)和带有HFNC模块的呼吸机(bellavista1000,Imtmedical,Buchs,瑞士)使用其匹配电路进行了评估。露点温度设定在31、34和37°C(set-DP)。在MR850中,将其设置为非侵入式模式(34°C/-3°C)和侵入式模式(40°C/-3°C),分别。在每个级别的set-DP,在5L/min或10L/min的梯度下,流量设定为从20L/min直至其最大设定极限。稳定后,露点温度,温度,相对湿度,并且记录来自套管的输送气体的流速。
    在任何设置DP下,这些设备之间的实际DP存在显着差异(p<0.001)。OH-70C和TNIsoftFlow50的实际DP低于set-DP,并且这两个设备的实际DP和集合DP之间的差异随着集合DP的增加而增加。AIRVO2,贝拉维斯塔1000(MR850),和HUMID-BH可以提供37°C的标称湿度。实际DP随着AIRVO2、TNIsoftFlow50和bellavista1000(MR850)中每个set-DP下的set-flow的增加而增加,但当设定流量大于60L/min时下降。在所有设备中,输送气体的实际T高于实际DP,在AIRVO2和HUMID-BH中高于设定DP。
    设置流,set-DP,和设备类型将影响输送气体的实际温度和湿度。AIRVO2,贝拉维斯塔1000(MR850),和HUMID-BH可以提供37°C的标称湿度,可能更适合气管切开患者。流量超过60L/min应谨慎设定。
    UNASSIGNED: The physiological effects of HFNC devices are closely related to temperature and humidity. HFNC devices from different manufacturers may have varied performances. It is unclear whether there are differences in the humidification performance of different HFNC devices and the degree of differences.
    UNASSIGNED: Four integrated HFNC devices (AIRVO 2, Fisher & Paykel Healthcare, Auckland, New Zealand; TNI softFlow 50, TNI Medical AG, Würzburg, Germany; HUMID-BH, RESPIRACARE, Shenyang, China; OH-70C, Micomme, Hunan, China) and a ventilator with an HFNC module (bellavista 1000, Imtmedical, Buchs, Switzerland) were evaluated using their matching circuits. The dew point temperature was set at 31, 34, and 37°C (set-DP). In MR850, it was set to non-invasive mode (34°C/-3°C) and invasive mode (40°C/-3°C), respectively. At each level of set-DP, the flow was set from 20 L/min up to its maximum set limit at a gradient of 5 L/min or 10 L/min. After stabilization, the dew point temperature, temperature, relative humidity, and flow rate of the delivered gas from the cannulas were recorded.
    UNASSIGNED: There were significant differences in actual-DP among these devices at any set-DP (p < 0.001). The actual-DP of OH-70C and TNI softFlow 50 was lower than set-DP, and the difference between the actual-DP and the set-DP of these two devices increased with the increase of set-DP. AIRVO 2, bellavista 1000 (MR850), and HUMID-BH can provide the nominal humidity at 37°C. The actual-DP increased with the increase of set-flow under each set-DP in AIRVO 2, TNI softFlow 50 and bellavista 1000 (MR850), but decreased when the set-flow was greater than 60 L/min. The actual-T of the delivered gas was higher than actual-DP in all devices and was higher than set-DP in AIRVO 2 and HUMID-BH.
    UNASSIGNED: Set-flow, set-DP, and types of devices will affect the actual temperature and humidity of the delivered gas. AIRVO 2, bellavista 1000 (MR850), and HUMID-BH can provide the nominal humidity at 37°C and may be more suitable for tracheotomy patients. The flow rate over 60 L/min should be set with caution.
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