UNASSIGNED: Lumbosacral transitional vertebra (LSTV) is a common spinal variant, with the reported prevalence varying from 8.1% to 36%. LSTV has been shown to alter the lumbo-pelvic parameters and reduce the benefits of total hip arthroplasty, but the specific effects of LSTV on hip development remain unclear. The aim of this study was thus to investigate the impact of LSTV on developmental alterations of the hip.
UNASSIGNED: A total of 310 individuals were categorized into three groups according to whole-body computed tomography (CT) imaging: a group with sacralization of 23 presacral vertebrae (PSV) (n=102), a group with lumbarization of 25 PSV (n=108), and a normal control group with 24 PSV (n=100). Quantitative parameters of the lumbo-pelvic-hip complex (LPHC) including lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), axial and sagittal acetabular anteversion angle (AAA), center-edge (CE) angle, Sharp angle, and femoral neck-shaft angle (FNSA) were measured and analyzed. Statistical analyses were used to compare the differences of these quantitative parameters among the three groups and to assess the relationship between hip and lumbar-pelvic parameters.
UNASSIGNED: Significant differences between each pair of three groups and the LSTV subgroups were only found in the sagittal AAA (left side: P=0.008; right side: P<0.001), with no differences found for the other parameters. Compared to the normal group (24 PSV), both the 23 PSV and 25 PSV groups exhibited increased values in the sagittal AAA, especially in the right side of the 23 PSV group. Only the sagittal AAA showed low-to-moderate positive correlations with pelvic parameters of PI (r=0.195-0.429; P=0.001-0.08) and PT (r=0.239-0.605; P=0.001-0.03).
UNASSIGNED: Variations of LSTV are correlated with the hip anatomical development via LPHC transmission and may potentially reduce the sagittal acetabular coverage, particularly in the 23 PSV subtype on the right side.

UNASSIGNED: Sacroiliac joint dysfunction (SIJD), while being the primary contributor to low back pain, is still disregarded and treated as low back pain. Mulligan\'s Mobilization with Movement (MWM) Techniques and Core Stability Exercises (CSE) are often used to treat low back pain. There is not much evidence that it is effective in SIJD. To evaluate the effectiveness of CSE coupled with MWM (CSE + MWM) in the treatment of SIJD.
UNASSIGNED: 39 patients with SIJD were recruited and randomly divided into distinct groups as follows: control group (n = 13), CSE group (n = 13) and CSE + MWM group (n = 13). The Numerical Pain Rating Scale (NPRS), the Roland Morris Disability Questionnaire (RMDQ), the Range of Motion (ROM), the Pressure Pain Threshold (PPT) and the pelvic tilt angle asymmetry ratio in the sagittal plane (PTAR) were used to gauge the intervention\'s success both before (M0) and after (M1) it. All experimental data were statistically analyzed.
UNASSIGNED: The SIJ-related pain metric significantly decreased in both the CSE + MWM group and the CSE group between M0 and M1, as determined by the NPRS and RMDQ. Between M0 and M1, The CSE group\'s left axial rotation ROM and lumbar flexion ROM were significantly decreased. The CSE + MWM group\'s extension ROM and left lateral flexion ROM both significantly increased between M0 and M1. In the difference variable (M1-M0), the CSE + MWM group substantially outperformed control group in the left lateral flexion ROM and outperformed the CSE group in the left axial rotation ROM.
UNASSIGNED: In individuals with SIJD, CSE + MWM is beneficial in lowering pain, disability, and function. Treatment with CSE and MWM approaches for SIJ appears to boost this efficacy.

Various assessments have contributed to inconsistent findings regarding the correlation between core stability and vertical jumps. Therefore, this study aimed to re-examine this correlation based on novel core stability assessments. Twenty-one recreationally active male college students (age, 21.7 ± 2.1 years; stature, 174.9 ± 6.7 cm; body mass, 67.7 ± 7.8 kg; leg length, 88.9 ± 4.8 cm; arm length, 87.8 ± 4.0 cm) participated in this experiment. Core stability was divided into static and dynamic core stabilities, with the static core stability measured using the Eight-Level Prone Bridge and Five-Level Side Bridge tests and the dynamic core stability measured using the Y Balance Test (YBT). These tests comprehensively evaluate core stability as it is defined. Kinematic and kinetic data on vertical jumps were collected to provide process information beyond the outcome performance. Subsequently, these data were correlated with core stability for a deeper insight into the relationship between core stability and the process and outcome performance of vertical jumps. The main results revealed that the Eight-Level Prone Bridge demonstrated moderate to substantial correlations with Δ Fy‾, Δ Iy, ΔDleftkneez, and ΔDleftankley (-0.62 ≤ r ≤ 0.52); the Five-Level Side Bridge exhibited moderate correlations with Δ Fx‾, Δ Fy‾, Δ Ix, Δ Iy, ΔDleftkneez, and ΔDleftankley (-0.52 ≤ r ≤ 0.59); YBT displayed moderate correlations with Fz‾, Fleftz‾, Δ Dleftankley, Δ Drightankley, Δ Dleftanklez, Δ Drightanklez, NΔ Tankley‾, and N Tleftanklez‾ (-0.54 ≤ r ≤ 0.54) during the propulsive phase of vertical jumps. However, no significant correlations were observed between static/dynamic core stability and jumping height. Therefore, individuals with greater core stability should experience improved process performance (better movement quality), although this benefit is ineffective in translating into jumping height improvement due to impaired explosive features. Coaches may consider core stability in training to trigger an improved process performance of the vertical jump when the technique is the key issue to be solved, although future studies are required to verify this further.

BACKGROUND: Patients with stroke frequently experience walking dysfunction. Core training can help improve balance and walking function in patients with stroke. However, core training movements in clinical practice are numerous and differently targeted. Therefore, this study will investigate the improvement of walking function in patients with combined diaphragmatic breathing maneuver (DBM) and draw-in breathing technique (ADIM) training.
METHODS: This single-blind, randomized controlled preliminary will analyze the viability of DBM combined ADIM training versus routine rehabilitation therapy in patients with stroke with early to mid-stroke. Patients will be randomly assigned to either the DBM and ADIM training or the routine rehabilitation training. We will recruit 42 stroke inpatients from the Second Rehabilitation Hospital of Shanghai who meet the trial criteria and measure the balance and walking functions and improvement of that after 4 weeks of intervention. The primary outcome is the 10 m maximum walking test (10MWT). The secondary outcomes indices include the limits of stability test (LOS), Berg balance scale test (BBS), Functional Ambulation Categories test (FAC), Timed Up and Go test (TUG), trunk impairment scale test (TIS), ultrasound indicators of the diaphragm and transversus abdominis (UI), rhythmic weight shift test (RWS), walk across test (WA), Fugl-Meyer assessment of lower extremity (FMA-LE), and Barthel index of ADL test.
CONCLUSIONS: The primary objective of this project was to investigate the effects of DBM combined with ADIM on balance capacity and walking function for patients with early to mid-stroke. The outcomes of this study will hold significant implications for future clinical applications in rehabilitation.
BACKGROUND: Chinese Clinical Trial Registry (ChiCTR), ID: ChiCTR2100054897. Registered on 28 December 2021.

Core stability is critical for improving athletic performance, reducing injury risks and is one of the most important elements of athletic training. However, the effect of core stability on landing kinetics during aerial skiing remains unclear, making relevant analysis and discussion an urgent issue to address. To enhance core stability training and landing performance aerial athletes, this study proposed a correlation analysis to investigate the effect of core stability on landing kinetics. Previous studies on aerial athletes have overlooked landing kinetics and lacked correlation analyses, leading to unsatisfactory analysis outcomes. The correlation analysis can be integrated with core stability training indices to analyze the effect of core stability on vertical and 360° jump landings. Therefore, this study can provide guidance for core stability training and athletic performance in aerial athletes.

Nanomedicine faces the challenges of infinite dilution, shear force, biological protein, or electrolyte competition. However, core cross-linking leads to biodegradability deficiency and brings inevitable side effects of nanomedicine on normal tissues. In order to overcome this bottleneck problem, we turn to amorphous poly(d,l)lactic acid (PDLLA)-dextran bottlebrush to emphasize the core stability of nanoparticles, and the amorphous structure offers an additional advantage of fast degradation property over the crystalline PLLA polymer. The graft density and side chain length of amorphous PDLLA together played important influence roles in controlling the architecture of nanoparticles. This effort produces structure-abundant particles, including micelles, vesicles, and large compound vesicles after self-assembly. Here, the amorphous bottlebrush PDLLA was verified to play a beneficial role in the structure stability and degradability of nanomedicines. The codelivery of the hydrophilic antioxidant of citric acid (CA), vitamin C (VC), and gallic acid (GA) via the optimum nanomedicines could effectively repair the SH-SY5Y cell damage caused by H2O2. The CA/VC/GA combination treatment repaired the neuronal function efficiently, and the cognitive abilities of senescence-accelerated mouse prone 8 (SAMP8) recovered.

BACKGROUND: This study aimed to investigate the effect of cognitive load on anticipatory postural adjustment (APA) latency in patients with non-specific chronic low back pain (NCLBP) and its relationship with pain-related functional changes.
METHODS: A cross-sectional study was conducted from December 15, 2022 to January 25, 2023. Participants were divided into a healthy control group (n = 29) and an NCLBP group (n = 29). Each group was assigned a single task of rapid arm raising and a dual task of rapid arm raising combined with a cognitive load. The cognitive load task was conducted using visual conflict. The APA latency for bilateral trunk muscles was observed using electromyography. The duration of electromyography recording in each task cycle was 28 s. Pain related-functional changes were evaluated using Roland-Morris Disability Questionnaire (RMDQ) before all tasks.
RESULTS: The APA latency for the right multifidus was significantly delayed in the NCLBP group [25.38, 95% confidence interval (CI) 13.41-37.35] than in the healthy control group (- 5.80, 95% CI - 19.28 to 7.68) during dual task (p = 0.0416). The APA latency for the right multifidus (25.38, 95% CI 13.41-37.35) and transverse abdominis/internal oblique (29.15, 95% CI 18.81-39.50) were significantly delayed compared with on the left side in the NCLBP group during dual task (- 3.03, 95% CI - 15.18-9.13, p = 0.0220; 3.69, 95% CI - 6.81 to 14.18, p = 0.0363). The latency delay of the right and left multifidus APA in the NCLBP group under the dual-task was positively correlated with RMDQ scores (r = 0.5560, p = 0.0017; r = 0.4010, p = 0.0311).
CONCLUSIONS: Cognitive load could induce APA delay in the right trunk muscles and co-activation pattern changes in bilateral trunk muscle APA in patients with NCLBP. The APA onset delay in multifidus is positively related to pain-related daily dysfunction. Trial Registration ChiCTR2300068580 (retrospectively registered in February 23, 2023).

Freestyle skiing aerials are characterized by technical elements including strength, flexibility and balance. Core stability in aerials can improve sporting performance.
OBJECTIVE: This study aimed to analyze the effect of 8 weeks of core stability training on core stability performance in aerials.
METHODS: Participants were randomly assigned to a control group (CG; n = 4male + 5female; age 15.89 ± 1.54 years; height 163.11 ± 6.19 cm; weight 55.33 ± 5.07 Kg) and a training group (TG; n = 4male+5female; age 16.11 ± 2.47 years; height 161.56 ± 5.25 cm; weight 57.56 ± 8.11 Kg). Body shape, the performance of core stability, and landing kinetics were measured after 8 weeks of core stability training. Independent sample t-tests were used to compare baseline values between groups. A two-way repeated-measures analysis of variance (ANOVA) (time × group) was used.
RESULTS: The TG improved body shape, and waist circumference (t = -2.333, p = 0.020). Performance of core stability, squat (t = -4.082, p = 0.004), trunk flexion isometric test (t = -4.150, p = 0.003), trunk lateral bending isometric test (t = -2.668, p = 0.008), trunk rotation isometric test (t = -2.666, p = 0.008), side bridge (t = -2.666, p = 0.008), back hyperextension (t = -4.116, p = 0.003), single foot triple jump (t = -4.184, p = 0.003), and single-leg balance with eyes closed (t = 4.167, p = 0.003). Performance in landing kinetics, End/Phase (t = -4.015, p = 0.004), sagittal axes (t = -4.598, p = 0.002), frontal axis (t = 3.116, p = 0.014), peak power hip changing range (t = 2.666, p = 0.017), peak power knee changing range (t = 2.256, p = 0.049).
CONCLUSIONS: Core stability training leads to improvements in body shape, the performance of core stability, and landing kinetics. Therefore, these improvements can improve the sporting performance in aerials competitions.

UNASSIGNED: Thoracolumbar vertebral compression fractures (TVCF) are caused by anterior flexion or vertical downward violence to the spine (Sezer et al. 2021). This study is aimed at investigating the effect of core stability training (CST) on unstable support surfaces in the postoperative rehabilitation of TVCF in the elderly. Methods. Ninety-eight patients with TVCF who underwent surgical treatment in our hospital from July 2021 to April 2022 were selected as study subjects. Then, they were divided into a research group receiving unstable support surface CST and a control group with conventional rehabilitation training according to the random number table method. Before and after the training, the X-ray machine was positioned and the anterior margin and middle height ratio and the posterior convex Cobb angle of the injured vertebrae were observed, and the balance detector was used to detect patients\' eye opening and closing trajectory length, Romberg rate, and to perform gait test. Patients\' pain, lumbar spine function, and quality of life were subsequently assessed using the Visual Analogue Scale (VAS), Oswestry Dysfunction Index (ODI), Generic Quality of Life Inventory-74 (GQOL-74), and patient satisfaction with rehabilitation was investigated. Results. After rehabilitation training, there was no statistically marked difference in eye-opening trajectory length between both groups (P > 0.05). The research group had higher scores than the control group in all dimensions of the anterior border of the injured vertebra, middle height ratio, and GQOL-74, while the posterior convex Cobb angle, closed-eye trajectory length, Romberg rate, VAS, and ODI were lower than the control group (P < 0.05). The research group also revealed better gait improvement and higher rehabilitation satisfaction than the control group after training (P < 0.05).
UNASSIGNED: Unstable support surface CST can effectively improve postoperative vertebral body rehabilitation, balance function, gait, pain conditions, and lumbar spine function in elderly TVCF patients, and enhance their quality of life and rehabilitation satisfaction. This trial is registered with ChiCTR2000014547.

UNASSIGNED: To observe the effect of 12-week core stability training on Cobb angle and the ratios of AEMG (averaged EMG) and IEMG (integral EMG) of paravertebral electromyography in thoracic and lumbar segments in adolescent idiopathic scoliosis (AIS) patients and offer a practical-based evidence for the rehabilitation treatment for AIS patients.
UNASSIGNED: 31 AIS female middle school students were randomly divided into an exercise group (n = 16, 12 weeks of core stability training, 3 times/week) and AIS group (n = 15). In addition, 15 female secondary school students without scoliosis were included as the normal group (the AIS group and normal group did not perform any regular physical exercise throughout the trial period and only receive regular evaluation and guidance). Before and after the experiment, the digital diagnostic equipment of Philips was used to examine the Cobb angle and Noraxon was used to measure the surface EMG signals of the back thoracic and lumbar paravertebral muscles.
UNASSIGNED: Compared with that before training, after 12 weeks of core stability training, the Cobb angle in the exercise group significantly decreased, and the ratio of AEMG (convex/concave) and IEMG (convex/concave) of paravertebral muscles in the thoracolumbar segment significantly decreased (P < 0.01, respectively); there was no significant difference in the above indicators in the AIS group before and after the experiment (P > 0.05, respectively). After 12 weeks of core stability training, compared with the AIS group, the Cobb angle decreased significantly (P < 0.01), and the ratio of AEMG (convex/concave) and IEMG (convex/concave) of paravertebral muscles in thoracolumbar segment decreased significantly (P < 0.01, P < 0.05). Compared with the normal group, the ratio of AEMG and IEMG of paravertebral muscles in thoracolumbar segment significantly increased (P < 0.01) in the AIS group (P < 0.01, respectively).
UNASSIGNED: The core stability training can significantly reduce the Cobb angle of AIS and correct the bad posture of scoliosis patients, which may be related to the balance of the electromyographic activities (convex concave side) of paravertebral muscles in AIS patients.