根据分子数据,已经在啮齿动物中鉴定出9种贾第鞭毛虫中的4种:G.muris,G.microti,G.Cricetidarum,和十二指肠G.共有7个十二指肠球藻组合(A,B,C,D,E,F,G)迄今为止已在啮齿动物中发现。据统计,人畜共患组合A和B占啮齿动物总基因型的74.88%(480/641)。对于人类的子集合A,AII占已确定的子组合的71.02%(1397/1967),其次是人工智能,占26.39%(519/1967),AIII占1.17%(23/1967),表明源自动物的人类十二指肠G.daudenalis感染的人畜共患可能性明显更大。对于啮齿动物的A型子组合,86.89%(53/61)的人确定了AI,AII为4.92%(3/61)。对于组合件B,在啮齿动物中发现60.84%(390/641)对人类具有人畜共患潜力。在环境样本中,人畜共患组合A和B在水样中占83.81%(533/636),新鲜农产品样品中86.96%(140/161),和土壤样品中的100%(8/8)。在人类中同时识别出相同的人畜共患潜能组合A或B,啮齿动物,和环境样本具有潜在的人畜共患传播之间的人与动物之间的环境。养殖啮齿动物和宠物啮齿动物的感染和人畜共患可能性高于动物园,实验室,野生啮齿动物。总之,应注意啮齿动物在贾第鞭毛虫病的人畜共患传播中的作用。除了啮齿动物,狗,猫,野生动物,牲畜可能参与人畜共患传播周期。本研究旨在探讨啮齿动物贾第鞭毛虫病的现状,并试图从“一个健康”的角度描述啮齿动物在贾第鞭毛虫病的人畜共患传播中的作用。
Four species of Giardia out of nine have been identified in rodents based on molecular data: G. muris, G. microti, G. cricetidarum, and G. duodenalis. A total of seven G. duodenalis assemblages (A, B, C, D, E, F, G) have been identified in rodents to date. The zoonotic assemblages A and B are responsible for 74.88% (480/641) of the total identified genotypes in rodents by statistic. For sub-assemblage A in humans, AII is responsible for 71.02% (1397/1967) of the identified sub-assemblages, followed by AI with 26.39% (519/1967) and AIII with 1.17% (23/1967), indicating a significantly greater zoonotic potential for G. duodenalis infections in humans originating from animals. For sub-assemblages of type A in rodents, AI was identified in 86.89% (53/61), and AII in 4.92% (3/61). For assemblage B, 60.84% (390/641) were identified in rodents as having zoonotic potential to humans. In environmental samples, the zoonotic assemblages A and B were responsible for 83.81% (533/636) in water samples, 86.96% (140/161) in fresh produce samples, and 100% (8/8) in soil samples. The same zoonotic potential assemblage A or B simultaneously identified in humans, rodents, and environment samples had potential zoonotic transmission between humans and animals via a synanthropic environment. The infections and zoonotic potential for G. duodenalis were higher in farmed rodents and pet rodents than that in zoo, lab, and wild rodents. In conclusion, the role of rodents in zoonotic transmission of giardiasis should be noticed. In addition to rodents, dogs, cats, wild animals, and livestock could be involved in the zoonotic transmission cycle. This study aims to explore the current situation of giardiasis in rodents and seeks to delineate the role of rodents in the zoonotic transmission of giardiasis from the One Health perspective.