Patient outcome assessment

患者结局评估
  • 文章类型: Journal Article
    背景:基于以人为中心的结果测量(PCOM)的质量改善(QI)计划在促进最佳姑息治疗方面发挥着重要作用。然而,PCOM的常规使用缓慢且难以实现,包括在QI计划中。
    目的:本研究旨在确定支持将PCOM作为医院姑息治疗常规实践的实施策略,以及实施理论,指导这些实施策略设计的模型和框架(TMF)。
    方法:根据JoannaBriggsInstitute(JBI)范围审查框架进行了范围审查。四个数据库(Medline,CINAHL,对Scopus和PubMed)进行了系统搜索,以查找1990年1月1日至2024年3月8日之间发表的文献。
    结果:115个独特的实施策略,从11项纳入的研究中确定,被映射到73项实施变更的专家建议(ERIC)离散实施策略上,涵盖52%的ERIC战略。最常用的类别是培训和教育利益相关者,并支持临床医生,然后发展利益相关者的相互关系,并使用评估和迭代策略。出现了三个关键主题:做什么;如何做;以及与谁一起做。在本次审查中,只有四项研究采用了TMF来指导实施策略的设计。
    结论:为了促进基于PCOM的QI计划的实施,应通过使用严格的TMF,根据已识别/潜在的障碍和促进因素制定策略。必须透明和一致地报告实施战略的组成部分,以便在未来的研究和实践中进行复制和衡量。
    此范围审查在其设计或执行中不直接涉及患者或公众。然而,这是一项实施研究的一部分,旨在将姑息治疗结果合作(PCOC)模式纳入中国一家癌症医院的常规临床实践.在正式实施之前,该医院的姑息治疗专业人员强调,需要对现有证据进行全面分析,以支持在其特定临床环境中有效采用PCOC模型。
    BACKGROUND: Quality improvement (QI) programs based on person-centred outcome measures (PCOMs) play an important role in promoting optimal palliative care. However, routine use of PCOMs has been slow and difficult to implement, including within QI programs.
    OBJECTIVE: This study aimed to identify implementation strategies that support the implementation of PCOMs as routine practice in hospital-based palliative care, as well as the implementation theories, models and frameworks (TMFs) guiding the design of these implementation strategies.
    METHODS: A scoping review was conducted in accordance with the Joanna Briggs Institute (JBI) Scoping Review framework. Four databases (Medline, CINAHL, Scopus and PubMed) were systematically searched for literature published between 1 January 1990 and 8 March 2024.
    RESULTS: One hundred and fifteen unique implementation strategies, identified from 11 included studies, were mapped onto the 73 Expert Recommendations for Implementing Change (ERIC) discrete implementation strategies, covering 52% of the ERIC strategies. The most commonly used categories were train and educate stakeholders, and support clinicians, followed by develop stakeholder interrelationships and use evaluation and iterative strategies. Three key themes emerged: what to do; how to do it; and who to do it with. Only four studies employed TMFs to guide the design of the implementation strategies in this review.
    CONCLUSIONS: To promote the implementation of PCOM-based QI programs, strategies should be developed based on identified/potential barriers and facilitators by using rigorous TMFs. The components of the implementation strategies must be reported transparently and consistently to enable replication and measurement in future research and practice.
    UNASSIGNED: This scoping review does not directly involve patients or the general public in its design or execution. However, it is part of an implementation study aimed at integrating the Palliative Care Outcome Collaboration (PCOC) model into routine clinical practice at a cancer hospital in China. Before the formal implementation, palliative care professionals from this hospital highlighted the need for a comprehensive analysis of existing evidence to support the effective adoption of the PCOC model in their specific clinical setting.
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  • 文章类型: Journal Article
    OBJECTIVE: This study aimed to clinically validate the nursing outcome \"Swallowing status: pharyngeal phase\" (1013).
    METHODS: A two-stage study was designed: (1) Chinese translation and cultural adaptation and (2) clinical validation. Internal consistency and interrater reliability tests were performed on 285 patients with laryngeal cancer, and an additional 130 patients were randomly selected from the 285 patients as an independent sample. Criterion-related validity tests were performed using the standardized swallowing assessment (SSA). Nursing outcome sensitivity was detected by scoring two time points.
    RESULTS: The Cronbach\'s alpha coefficients were 0.951 for the nursing outcome and 0.942-0.965 for each indicator. The interclass correlation coefficient (ICC) values for each indicator ranged from 0.73 to 0.929. The scores of the nursing outcome were negatively correlated with the SSA scores (r = -0.555, p < 0.01). With the exception of two indicators, there was a significant difference (p < 0.05) between the total scores of the scale and its 11 indicator scores for the two time points. The results indicated that the nursing outcome \"Swallowing status: pharyngeal phase\" (1013) exhibited satisfactory psychometric properties and high sensitivity to change.
    CONCLUSIONS: The nursing outcome \"Swallowing status: pharyngeal phase\" (1013) demonstrated good reliability, validity, and sensitivity in patients with laryngeal cancer.
    CONCLUSIONS: The nursing outcome \"Swallowing status: pharyngeal phase\" (1013) can be used to assess swallowing function in patients with laryngeal cancer and provide guidance for the development of rehabilitation intervention plans and nursing care.
    目的: 本研究旨在对护理结局“吞咽状态:咽期”(1013)进行临床验证。 方法: 本研究分为两阶段:(1)汉化及文化调适;(2)临床验证。对285名喉癌患者进行内部一致性和评分者间信度检验;另外从285名患者中随机选取130名患者作为独立样本, 采用标准吞咽功能评价量表进行效标关联效度检验;通过两个时间点的测量评分来检测护理结局灵敏度。 结果: 护理结局的Cronbach\'s α系数为 0. 951, 各指标的Cronbach\'s 系数为0.942‐0.965, 各指标的评分者间信度检验(ICC)为0.73‐0.929。护理结局总分与标准吞咽功能评价量表得分具有负相关性(r = ‐0.555, P<0.01)。除两个指标外, 两个时间点测量的量表总得分及其11个指标得分之间差异显著(p<0.05)。结果显示, 护理结局“吞咽状态:咽期”(1013)具有令人满意的心理测量学特性及对变化的高度敏感性。 结论: 护理结局“吞咽状态:咽期”(1013)在喉癌患者中的临床验证中显示有较好的信效度和灵敏度。 对护理实践的影响: 护理结局“吞咽状态:咽期”(1013)可用于喉癌患者的吞咽功能评估, 为制定康复干预计划和护理措施提供指导。.
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  • 文章类型: Journal Article
    数字技术已经成为牙科植入的变革性工具,深刻地提高了多个方面的准确性和有效性,如诊断,术前治疗计划,外科手术,和恢复交付。射线照相数据和口内数据的多重集成,有时通过虚拟计划软件使用面部扫描数据或电子脸弓,能够对硬软组织和未来修复的位置进行全面的三维可视化,导致诊断精度提高。在虚拟手术设计中,假体布置和个体解剖细节的结合使得关键程序的虚拟执行(例如,植入物放置,扩展应用程序,等。)通过分析横截面图像和三维表面模型的重建。经过验证,包括模板在内的数字技术的利用,导航,组合技术,植入机器人实现了将虚拟治疗计划无缝转移到实际手术部位,最终导致增强的手术结果和高度改进的准确性。在修复交付中,数字印模技术,阴影匹配,假体制造有了进步,实现无缝数字数据转换和临床医生和技术人员之间的有效沟通。与临床医学相比,牙科种植中的人工智能(AI)技术主要集中在诊断和预测上。人工智能支持的术前计划和手术仍处于发展阶段,由于临床病例的复杂性和伦理考虑,从而限制了广泛采用。
    Digital technology has emerged as a transformative tool in dental implantation, profoundly enhancing accuracy and effectiveness across multiple facets, such as diagnosis, preoperative treatment planning, surgical procedures, and restoration delivery. The multiple integration of radiographic data and intraoral data, sometimes with facial scan data or electronic facebow through virtual planning software, enables comprehensive 3-dimensional visualization of the hard and soft tissue and the position of future restoration, resulting in heightened diagnostic precision. In virtual surgery design, the incorporation of both prosthetic arrangement and individual anatomical details enables the virtual execution of critical procedures (e.g., implant placement, extended applications, etc.) through analysis of cross-sectional images and the reconstruction of 3-dimensional surface models. After verification, the utilization of digital technology including templates, navigation, combined techniques, and implant robots achieved seamless transfer of the virtual treatment plan to the actual surgical sites, ultimately leading to enhanced surgical outcomes with highly improved accuracy. In restoration delivery, digital techniques for impression, shade matching, and prosthesis fabrication have advanced, enabling seamless digital data conversion and efficient communication among clinicians and technicians. Compared with clinical medicine, artificial intelligence (AI) technology in dental implantology primarily focuses on diagnosis and prediction. AI-supported preoperative planning and surgery remain in developmental phases, impeded by the complexity of clinical cases and ethical considerations, thereby constraining widespread adoption.
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  • 文章类型: Journal Article
    阿尔伯塔省卒中计划CT评分(ASPECTS)是一种广泛使用的评分系统,用于评估梗塞范围和位置。我们旨在研究ASPERTS亚区域参与急性缺血性卒中(AIS)长期功能结局的预后价值。
    纳入了2019年1月至2020年12月期间AIS和前循环大血管狭窄和闭塞的连续患者。使用治疗后磁共振扩散加权成像评估每位患者的ASPECTS评分和亚区域受累情况。进行了单变量和多变量回归分析,以确定与3个月不良功能结局相关的子区域(改良的Rankin量表评分,3-6)在再灌注和药物治疗队列中,分别。此外,使用受试者工作特征曲线和DeLong检验比较了基于区域的ASPERTS和ASPERTS评分方法之间的预后效率。
    共有365名患者(中位年龄,64岁;70%的男性)被包括在内,其中169人结果不佳。在再灌注治疗队列中,多变量回归分析显示,左半球卒中中左侧M4皮质区的受累(校正比值比[aOR]5.39,95%可信区间[CI]1.53-19.02)和右半球卒中右侧M3皮质区的受累(aOR4.21,95%CI1.05-16.78)与不良功能结局独立相关。在医学治疗队列中,左半球卒中涉及左M5皮质区(aOR2.87,95%CI1.08-7.59)和尾状核(aOR3.14,95%CI1.00-9.85),右半球卒中涉及右M3皮质区(aOR4.15,95%CI1.29-8.18)和内囊(aOR3.94,95%CI1.22-12.78)与残疾后卒中风险增加相关.此外,与传统的ASPERTS评分方法相比,基于区域的ASPERTS显着提高了预后效率。
    受累于受累半球的特定ASPECTS亚区域与卒中后3个月更差的功能结局相关,关键次区域分布因临床管理而异。因此,基于区域的ASPECTS可以为指导AIS患者的个体决策和神经系统恢复提供额外价值。
    UNASSIGNED: The Alberta Stroke Program CT Score (ASPECTS) is a widely used rating system for assessing infarct extent and location. We aimed to investigate the prognostic value of ASPECTS subregions\' involvement in the long-term functional outcomes of acute ischemic stroke (AIS).
    UNASSIGNED: Consecutive patients with AIS and anterior circulation large-vessel stenosis and occlusion between January 2019 and December 2020 were included. The ASPECTS score and subregion involvement for each patient was assessed using posttreatment magnetic resonance diffusion-weighted imaging. Univariate and multivariable regression analyses were conducted to identify subregions related to 3-month poor functional outcome (modified Rankin Scale scores, 3-6) in the reperfusion and medical therapy cohorts, respectively. In addition, prognostic efficiency between the region-based ASPECTS and ASPECTS score methods were compared using receiver operating characteristic curves and DeLong\'s test.
    UNASSIGNED: A total of 365 patients (median age, 64 years; 70% men) were included, of whom 169 had poor outcomes. In the reperfusion therapy cohort, multivariable regression analyses revealed that the involvement of the left M4 cortical region in left-hemisphere stroke (adjusted odds ratio [aOR] 5.39, 95% confidence interval [CI] 1.53-19.02) and the involvement of the right M3 cortical region in right-hemisphere stroke (aOR 4.21, 95% CI 1.05-16.78) were independently associated with poor functional outcomes. In the medical therapy cohort, left-hemisphere stroke with left M5 cortical region (aOR 2.87, 95% CI 1.08-7.59) and caudate nucleus (aOR 3.14, 95% CI 1.00-9.85) involved and right-hemisphere stroke with right M3 cortical region (aOR 4.15, 95% CI 1.29-8.18) and internal capsule (aOR 3.94, 95% CI 1.22-12.78) affected were related to the increased risks of poststroke disability. In addition, region-based ASPECTS significantly improved the prognostic efficiency compared with the conventional ASPECTS score method.
    UNASSIGNED: The involvement of specific ASPECTS subregions depending on the affected hemisphere was associated with worse functional outcomes 3 months after stroke, and the critical subregion distribution varied by clinical management. Therefore, region-based ASPECTS could provide additional value in guiding individual decision making and neurological recovery in patients with AIS.
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  • 文章类型: Journal Article
    从医疗保健提供者的角度评估上海癌症死亡患者的死亡和死亡质量。
    这项横断面研究于2023年4月至7月在上海进行。在八家医疗机构工作的261名医疗保健提供者的便利样本参加了。要求每位参与者使用中国患者良好死亡量表(GDS-PCN)评估一名最近接受护理的已故患者的死亡和死亡质量。量表包括家庭陪伴(八个项目),死与和平(六项),专业护理(六项),准备和不后悔(五个项目),维护尊严(四项),保持自主权(四项),和身体健康(三项)七个维度,36项。
    GDS-PCN总分为144.11±17.86。专业护理维度得分最高(4.21±0.58),而准备和无后悔维度得分最低(3.75±0.70)。GDS-PCN分数的显著差异是基于医疗机构的等级,病房类型,住院时间,关于病情的沟通,治疗,以及与医疗保健提供者的死亡相关主题,决策风格(P<0.05)。在社区卫生服务中心和临终关怀病房接受护理的患者中,死亡患者的死亡和死亡质量较高,那些住院超过15天的人,那些讨论过他们个人情况的人,治疗,和死亡相关的话题与医疗保健提供者在更大程度上;和那些参与决策的人(P<0.05)。
    上海癌症患者死亡和死亡的总体质量是中高的,但在准备、无悔维度和保持自主性维度上的死亡和死亡质量仍有提升空间。提高临终关怀服务的利用率以及患者与医疗保健提供者之间更好的沟通可能会提高死者的死亡和死亡质量。在中国大陆,需要从不同的角度和更广泛的范围对这一主题进行未来的研究。
    UNASSIGNED: To evaluate the quality of dying and death among deceased patients with cancer in Shanghai from the perspective of healthcare providers.
    UNASSIGNED: This cross-sectional study was conducted in Shanghai from April to July 2023. A convenience sample of 261 healthcare providers working at eight healthcare institutions participated. Each participant was asked to evaluate the quality of dying and death of one deceased patient who had been cared for recently using the Good Death Scale for patients in China (GDS-PCN). The scale included family companionship (eight items), dying with peace (six items), professional care (six items), preparation & no regrets (five items), maintaining dignity (four items), keeping autonomy (four items), and physical wellbeing (three items) seven dimensions, 36 items.
    UNASSIGNED: The total GDS-PCN score was 144.11 ± 17.86. The professional care dimension scored the highest (4.21 ± 0.58), whereas the preparation and no regret dimension scored the lowest (3.75 ± 0.70). Significant differences in the GDS-PCN scores were based on the healthcare institution grade, ward type, hospitalization duration, communication about the condition, treatment, and death-related topics with the healthcare provider, and decision-making style (P < 0.05). The quality of dying and death of the deceased patients was higher among those who received care in community health service centers and hospice wards, those who had been hospitalized for more than 15 days, those who had discussed their personal conditions, treatment, and death-related topics with healthcare providers to a greater extent; and those who were involved in decision-making (P < 0.05).
    UNASSIGNED: The overall quality of dying and death among cancer patients in Shanghai is moderate to high, but the quality of dying and death in the preparation and no regret dimension and the keeping autonomy dimension still have room for improvement. Increased utilization of hospice care and better communication between patients and healthcare providers may enhance decedents\' quality of dying and death. Future research on this topic is required from different perspectives and on a broader scale in the mainland of China.
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  • 文章类型: Comparative Study
    该研究旨在评估现有文献,并比较使用经腹膜(TP)和腹膜后(RP)入路的机器人辅助肾部分切除术(RAPN)治疗后外侧肾肿瘤的围手术期结果。系统地搜索了Embase,PubMed,和Cochrane图书馆的文献数据库。合格的研究是比较TP-RAPN和RP-RAPN治疗后外侧肾肿瘤的研究。使用ReviewManager5.3对纳入研究的数据进行分析和总结,包括比较基线患者和肿瘤特征,术中和术后结果,和肿瘤结果。分析包括五项符合纳入标准的研究,共有1440例患者(814例接受RP-RAPN,626例接受TP-RAPN)。两组在年龄上无显著差异,性别,BMI,R.E.N.A.L.得分,和肿瘤大小。值得注意的是,与TP-RAPN相比,RP-RPN组手术时间(OT)较短(MD:17.25,P=0.01),住院时间(LOS)(MD:0.37,P<0.01),估计失血量(EBL)较低(MD:15.29,P<0.01)。然而,两组患者热缺血时间(WIT)差异无统计学意义(MD:-0.34,P=0.69),总并发症(RR:1.25,P=0.09),主要并发症(Clavien-Dindo分级≥3)(RR:0.97,P=0.93),和阳性手术切缘(PSM)(RR:1.06,P=0.87)。系统评价和荟萃分析提示RP-RPN在OT方面可能更有利于后外侧肾肿瘤。EBL,还有LOS,但是在WIT中没有发现显着差异,整体并发症,主要并发症,和PSM。两种手术方法都是安全的,但是最终的优势仍然不确定。
    The study aims to assess the available literature and compare the perioperative outcomes of robotic-assisted partial nephrectomy (RAPN) for posterior-lateral renal tumors using transperitoneal (TP) and retroperitoneal (RP) approaches. Systematically searched the Embase, PubMed, and Cochrane Library databases for literature. Eligible studies were those that compared TP-RAPN and RP-RAPN for posterior-lateral renal tumors. The data from the included studies were analyzed and summarized using Review Manager 5.3, which involved comparing baseline patient and tumor characteristics, intraoperative and postoperative outcomes, and oncological outcomes. The analysis included five studies meeting the inclusion criteria, with a total of 1440 patients (814 undergoing RP-RAPN and 626 undergoing TP-RAPN). Both groups showed no significant differences in age, gender, BMI, R.E.N.A.L. score, and tumor size. Notably, compared to TP-RAPN, the RP-RAPN group demonstrated shorter operative time (OT) (MD: 17.25, P = 0.01), length of hospital stay (LOS) (MD: 0.37, P < 0.01), and lower estimated blood loss (EBL) (MD: 15.29, P < 0.01). However, no significant differences were found between the two groups in terms of warm ischemia time (WIT) (MD: -0.34, P = 0.69), overall complications (RR: 1.25, P = 0.09), major complications (the Clavien-Dindo classification ≥ 3) (RR: 0.97, P = 0.93), and positive surgical margin (PSM) (RR: 1.06, P = 0.87). The systematic review and meta-analysis suggests RP-RAPN may be more advantageous for posterior-lateral renal tumors in terms of OT, EBL, and LOS, but no significant differences were found in WIT, overall complications, major complications, and PSM. Both surgical approaches are safe, but a definitive advantage remains uncertain.
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  • 文章类型: Multicenter Study
    目的:本研究旨在研究患者体验的具体维度与患者总体满意度之间的相关性差异。
    方法:描述性,采用横断面设计收集患者体验和总体满意度数据.
    方法:参与者在一家三级综合医院招募,一家三级专科医院,上海一家二级医院,中国。这三个机构代表了中国医疗保健系统中的主要医院类型。
    方法:招募1532名住院患者,1469年被包括在内。纳入标准如下:(1)接受住院服务至少2天;(2)能够理解问卷中的问题;(3)年龄>18岁。排除认知功能受损并完成缺少信息的问卷的患者。
    方法:使用住院护理体验量表测量患者体验,在中国被广泛使用。使用10点反应选项测量患者的总体满意度。
    结果:LASSO(最小绝对收缩和选择算子)回归结果表明,作为惩罚因子(λ)=0.0162,年龄,婚姻状况,财务状况,该模型保留了住院时间和住院次数以及六个方面的护理。当λ增加到0.1862时,只有四个患者经验变量,可能对患者满意度影响最大,留在模型中。情绪支持的患者体验是解释患者满意度的最重要维度(β=0.1564),第二个最重要的维度是入院和出院管理(β=0.1562),第三是监测和应对疾病进展(β=0.0613)。
    结论:患者的情绪支持体验,入院和出院管理,监测和应对疾病的进展,信息和教育是解释患者满意度的最重要维度。
    This study aimed to examine the differential magnitude of associations between specific dimensions of patient experience and overall patient satisfaction.
    A descriptive, cross-sectional design was used to collect patient experience and overall satisfaction data.
    Participants were recruited at one tertiary general hospital, one tertiary specialised hospital, and one secondary hospital in Shanghai, China. These three institutes represent the main kinds of hospitals in the Chinese healthcare system.
    1532 inpatients were recruited, and 1469 were included. The inclusion criteria were as follows: (1) having received inpatient service for at least 2 days; (2) able to understand the questions in the questionnaires; and (3) aged>18 years old. Patients who had impaired cognitive function and completed the questionnaires with missing information were excluded.
    Patient experience was measured using the Inpatient Experience with Nursing Care Scale, which is widely used in the China. The overall patient satisfaction was measured with 10-point response option.
    The LASSO (least absolute shrinkage and selection operator) regression results showed that as the penalty factor (λ) = 0.0162, age, marriage status, financial status, length of hospital stay and numbers of previous of hospitalisation and six dimensions of nursing care remained in the model. As λ increases to 0.1862, only four patient experience variables, potentially the most influential on patient satisfaction, remained in the model. Patient experience with emotional support was the most significant dimension explaining patient satisfaction (β=0.1564), the second most significant dimension was admission and discharge management (β=0.1562), and the third was monitoring and coping with the progress of diseases (β=0.0613).
    Patient experience with emotional support, admission and discharge management, monitoring and coping with the progress of diseases, and information and education are the most significant dimensions explaining patient satisfaction.
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  • 文章类型: Journal Article
    背景:迄今为止,很少有报道评估经皮椎体后凸成形术(PKP)治疗骨质疏松性椎体压缩性骨折(OVCFs)的长期结局,影响该手术长期结局的因素尚不确定.
    方法:2012年6月至2012年12月,共有91例患者接受了胸腰椎OVCFsPKP治疗。术前和随访10年后记录疼痛视觉模拟评分(VAS)和Oswestry残疾指数(ODI)。可能影响手术结果的因素,比如性别,年龄,高度,体重,高血压,糖尿病,受伤原因,骨折段,住院时间,既往脊柱手术史,术前骨密度(BMD),术前VAS和ODI评分,手术长度,骨水泥用量,术后规范化抗骨质疏松治疗,和其他新的椎骨骨折,采用多元线性回归分析末次随访时的VAS和ODI评分。分析影响疗效的相关因素。
    结果:术前和最终随访疼痛VAS分别为7.9±1.1和2.2±1.1。ODI评分分别为30.4±4.2和10.7±2.6。差异有统计学意义(P<0.05)。大多数患者是65-75岁的女性,他们遭受了低能量伤害,大部分骨折节段在胸腰椎区(T11-L2)。在最后的后续访问中,12例(13.19%)出现其他新的椎体骨折,出院后继续坚持抗骨质疏松治疗33例(36.26%)。多元线性回归分析显示末次随访时性别、VAS评分差异有统计学意义(P<0.05),和年龄之间,损伤原因及术后规范抗骨质疏松治疗和末次随访ODI(P<0.05)。其他因素与末次随访VAS、ODI评分比较差异均无统计学意义(P>0.05)。
    结论:PKP术后的长期结果令人满意。年龄,性别,受伤原因,术后规范化抗骨质疏松治疗可能是影响远期预后的因素。
    BACKGROUND: To date, few reports have evaluated the long-term outcome of percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs) and the factors influencing the long-term outcome of this procedure are uncertain.
    METHODS: A total of 91 patients underwent PKP for thoracolumbar OVCFs from June 2012 to December 2012. Pain Visual Analogue Scores (VAS) and Oswestry Disability Index (ODI) were recorded preoperatively and after 10-year follow-up. Factors that may affect surgical outcome, such as gender, age, height, weight, hypertension, diabetes, cause of injury, fracture segment, length of hospitalization, history of previous spinal surgery, preoperative bone mineral density (BMD), preoperative VAS and ODI scores, length of surgery, bone cement dosage, postoperative standardized anti-osteoporosis treatment, and other new vertebral fractures, were analyzed by multiple linear regression with VAS and ODI scores at the last follow-up. The correlation factors affecting the efficacy were analyzed.
    RESULTS: The preoperative and final follow-up pain VAS was 7.9 ± 1.1 and 2.2 ± 1.1. ODI scores were 30.4 ± 4.2 and 10.7 ± 2.6. The difference was statistically significant (P < 0.05). Most of the patients were females aged 65-75 years who suffered low-energy injuries, with most of the fracture segments in the thoracolumbar region (T11-L2). At the final follow-up visit, 12 cases (13.19%) developed other new vertebral fractures, and 33 cases (36.26%) continued to adhere to anti-osteoporosis treatment after discharge. Multiple linear regression analysis showed that there was a statistical difference between gender and VAS score at the last follow-up (P < 0.05), and between age, cause of injury and postoperative standardized anti-osteoporosis treatment and ODI at the last follow-up (P < 0.05). There were no statistically significant differences between the other factors and the final follow-up VAS and ODI scores (P > 0.05).
    CONCLUSIONS: The long-term outcome after PKP is satisfactory. Age, gender, cause of injury, and standardized postoperative anti-osteoporosis treatment may be factors affecting the long-term outcome.
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  • 文章类型: Journal Article
    目的:老年人晕厥的治疗给医疗系统带来了负担。我们使用了五种危险分层工具来预测老年晕厥患者的短期不良结局。
    方法:这是一项对城市学术医院急诊科晕厥患者(年龄≥60岁)的回顾性分析。数据使用急诊科晕厥风险分层(ROSE)进行评估,旧金山晕厥规则(SFSR),FAINT,加拿大晕厥风险评分(CSRS),和波士顿晕厥标准(BSC)工具。灵敏度,特异性,准确度,阳性和阴性预测值(NPV),计算每种工具的阳性和阴性似然比,并比较1个月内的不良事件.
    结果:总计,分析了221例患者(平均年龄75.6岁)。59例患者(26.7%)在1个月内发生不良事件。对于玫瑰,SFSR,FAINT,CSRS和BSC工具,敏感性为81.3%,76.3%,93.2%,71.2%,94.9%,特异性为88.3%,87.7%,56.8%,71.6%,和67.3%,NPV为92.9%,91.0%,95.8%,87.2%,和97.3%,分别。
    结论:五种评估工具可用于医生筛查老年晕厥患者的短期不良事件风险,根据病人的实际情况。
    OBJECTIVE: Treatment of syncope in older adults places a burden on healthcare systems. We used five risk stratification tools to predict short-term adverse outcomes in older patients with syncope.
    METHODS: This was a retrospective analysis of patients with syncope (age ≥60 years) in the emergency department of an urban academic hospital. The data were evaluated using the Risk Stratification of Syncope in the Emergency Department (ROSE), San Francisco Syncope Rule (SFSR), FAINT, Canadian Syncope Risk Score (CSRS), and Boston Syncope Criteria (BSC) tools. Sensitivity, specificity, accuracy, positive and negative predictive value (NPV), and positive and negative likelihood ratios of each tool were calculated and compared for adverse events within 1 month.
    RESULTS: In total, 221 patients (average age 75.6 years) were analyzed. Fifty-nine patients (26.7%) had experienced an adverse event within 1 month. For the ROSE, SFSR, FAINT, CSRS and BSC tools, sensitivities were 81.3%, 76.3%, 93.2%, 71.2%, and 94.9%, specificities were 88.3%, 87.7%, 56.8%, 71.6%, and 67.3%, and NPVs were 92.9%, 91.0%, 95.8%, 87.2%, and 97.3%, respectively.
    CONCLUSIONS: The five assessed tools could be useful for physicians in screening older patients with syncope for the risk of short-term adverse events, according to the patient\'s actual situation.
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  • 文章类型: Meta-Analysis
    背景:本研究的目的是进行系统评价和荟萃分析,以检查血管活性-肌力评分(VIS)与手术患者预后之间的关系。
    方法:两名独立的审阅者搜索了PubMed,WebofScience,EMBASE,Scopus,科克伦图书馆,谷歌学者,和CNKI数据库从2010年11月开始,当VIS首次发布时,到2022年12月。通过手动搜索纳入研究的参考列表确定了其他研究。合格的研究是那些以英文发表的评估VIS与儿童和成人手术患者的短期或长期患者预后之间的关联的研究。使用RevManManager5.3版进行荟萃分析,质量评估遵循JoannaBriggs研究所(JBI)关键评估清单。
    结果:共有58项研究包括29,920名患者,其中34人符合荟萃分析的条件。发现术后早期VIS与长时间机械通气相关(OR5.20,95%CI3.78-7.16),死亡率(OR1.08,95%CI1.05-1.12),急性肾损伤(AKI)(OR1.26,95%CI1.13-1.41),不良结果(OR1.02,95%CI1.01-1.04),和ICU住院时间(LOS)(OR3.50,95%CI2.25-5.44)。VIS作为结果预测因子的最佳临界值在研究之间有所不同,范围从10到30。
    结论:术后早期VIS升高与各种不良结局相关,包括急性肾损伤(AKI),机械通气持续时间,死亡率,糟糕的结果,和ICU住院时间(LOS)。在返回重症监护病房(ICU)时监测VIS可以帮助医疗团队进行风险分层。有针对性的干预措施,和家长咨询。
    背景:PROSPEROCRD42022359100.
    The objective of this study is to conduct a systematic review and meta-analysis examining the relationship between the vasoactive-inotropic score (VIS) and patient outcomes in surgical settings.
    Two independent reviewers searched PubMed, Web of Science, EMBASE, Scopus, Cochrane Library, Google Scholar, and CNKI databases from November 2010, when the VIS was first published, to December 2022. Additional studies were identified through hand-searching the reference lists of included studies. Eligible studies were those published in English that evaluated the association between the VIS and short- or long-term patient outcomes in both pediatric and adult surgical patients. Meta-analysis was performed using RevMan Manager version 5.3, and quality assessment followed the Joanna Briggs Institute (JBI) Critical Appraisal Checklists.
    A total of 58 studies comprising 29,920 patients were included in the systematic review, 34 of which were eligible for meta-analysis. Early postoperative VIS was found to be associated with prolonged mechanical ventilation (OR 5.20, 95% CI 3.78-7.16), mortality (OR 1.08, 95% CI 1.05-1.12), acute kidney injury (AKI) (OR 1.26, 95% CI 1.13-1.41), poor outcomes (OR 1.02, 95% CI 1.01-1.04), and length of stay (LOS) in the ICU (OR 3.50, 95% CI 2.25-5.44). The optimal cutoff value for the VIS as an outcome predictor varied between studies, ranging from 10 to 30.
    Elevated early postoperative VIS is associated with various adverse outcomes, including acute kidney injury (AKI), mechanical ventilation duration, mortality, poor outcomes, and length of stay (LOS) in the ICU. Monitoring the VIS upon return to the Intensive Care Unit (ICU) could assist medical teams in risk stratification, targeted interventions, and parent counseling.
    PROSPERO CRD42022359100.
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