■关于老年参与者髋部骨折的虚弱状态与跌倒之间的关系的研究有限。这项研究旨在调查经历过髋部骨折的老年人的虚弱与跌倒之间的关系。
■从2023年6月到2024年1月,研究人群包括253名60岁及以上的髋部骨折患者。他们被送往三级护理医院的骨科。我们排除了信息不完整的参与者。5个项目的FRAIL量表(疲劳,阻力,步行,疾病,和体重减轻)用于评估虚弱状态和患者自我报告的跌倒。我们使用logistic回归模型分析老年髋部骨折患者的虚弱与跌倒之间的关系。亚组分析,和分层分析。
■最后,在这项研究中发现了174名髋部骨折的老年参与者,其中155人(89.1%)下跌。在155个瀑布中,健壮组39人(78.0%),65人(91.5%)在前虚弱组,虚弱组51例(96.2%)。一项分析显示,在60岁以上的髋部骨折患者中,每个额外的虚弱评分点与更高的跌倒可能性显著相关(OR:1.97,95CI:1.10~3.52,p<0.05).虽然脆弱是一个分类变量,这种关联更强,虚弱前期组的OR为2.68(95%CI:0.71-10.21)和7.95(95%CI:1.11-57.08),与稳健组相比(趋势<0.005)。在亚组分析中,根据性别观察到虚弱和跌倒之间的相互作用。在分层分析中,在男性和女性组之间,虚弱状态与跌倒之间的关系显着不同(男性OR:1.49,95%CI:0.71t-3.13;女性OR:7.54,95%CI:1.13至50.32,相互作用p=0.043)。
■研究表明,虚弱和跌倒之间存在显著的相关性,性别和虚弱对跌倒发生率的增加有相互作用的影响。因此,需要对不同疾病人群进行进一步研究,以探索虚弱状态与跌倒之间的联系.有必要进行大规模的前瞻性研究来阐明这种关系的因果关系。
■中国临床试验注册中心(ChiCTR2300073031)。
UNASSIGNED: There is limited research on the relationship between frailty status and falls in hip fractures in older participants. This study aimed to investigate the relationship between frailty and falls in older adults who had experienced a hip fracture.
UNASSIGNED: From June 2023 to January 2024, the study population comprised 253 hip fracture patients aged 60 years and over. They were admitted to the orthopedic department of a tertiary care hospital. We excluded participants with incomplete information. The 5-item FRAIL scale (Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight) was used to assess frailty status and the patient\'s self-reported falls. We analyzed the relationship between frailty and falls in older hip fracture patients using logistic regression models, subgroup analyses, and stratified analyses.
UNASSIGNED: Finally, 174 older participants with hip fractures were identified in this study, where 155 (89.1%) had falls. Among 155 falls, 39 (78.0%) were in the robust group, 65 (91.5%) were in the pre-frail group, and 51 (96.2%) were in the frail group. An analysis revealed that among more than 60 years old hip fracture patients, each additional point in frailty score was significantly linked to a higher likelihood of experiencing a fall (OR: 1.97, 95% CI: 1.10-3.52, p < 0.05). While frailty appeared as a categorical variable, this association was stronger with an OR of 2.68 (95% CI: 0.71-10.21) in the pre-frailty group and 7.95 (95% CI: 1.11-57.08), compared to the robust group (p for trend < 0.005). In subgroup analyses, an interaction was observed between frailty and falling according to sex. In stratified analyses, the relationship between frailty status and fall significantly differed between the male and female groups (male OR: 1.49, 95% CI: 0.71 -3.13; female OR: 7.54, 95% CI: 1.13 - 50.32, p for interaction = 0.035).
UNASSIGNED: The study revealed a notable correlation between frailty and falls, with gender and frailty showing an interaction impact on the increased occurrence of falls. Therefore, further research across diverse disease populations is needed to explore the link between frailty status and falls. Large-scale prospective studies are necessary to clarify the causality of this relationship.
UNASSIGNED: Chinese Clinical Trial Registry (ChiCTR2300073031).