Hip fracture

髋部骨折
  • 文章类型: Journal Article
    背景:研究的目的是:1)评估对2023年美国国家健康与护理卓越研究所(NICE)新标准的满意度,该标准用于选择全髋关节置换术(THA)而不是半髋关节置换术(HA)和治疗移位的髋关节囊内骨折的手术建议;2)描述为什么不符合NICE标准时进行THA;3)确定对这些指南的满意度是否与改善相关。
    方法:对2010年至2022年在一个三级学术中心接受THA治疗的移位性髋关节囊内骨折患者进行回顾性分析。审查了术前患者特征,以确定THA的适应症是否符合NICE标准。操作详情,围手术期并发症,重新操作,并记录手术后12个月内的关节翻修术.
    结果:使用了196例患者(63%为女性;年龄67±10岁)的数据。有161个THA(82.1%)满足NICE标准。当不符合NICE标准(n=35)时,进行THA的两个最常见原因包括术前影像学骨关节炎(Tönnnis等级≥2;48.6%)和患者年龄降低(<65岁;31.5%)。对NICE标准的满意度与较少的围手术期并发症相关(0.6对37.1%;P<0.001)。再次手术(0.6对31.4%;P<0.001),和修订(0.6对28.6%;P<0.001)。最常见的翻修原因是假体周围骨折,可能继发于使用非骨水泥股骨柄(196中的171,87.2%)。
    结论:对新NICE标准的满意度与改善围手术期结局相关。有必要进行进一步的研究,以确定在选择患者时是否需要考虑先前存在的髋关节骨关节炎和较年轻的年龄。
    BACKGROUND: The objectives of the study were to: (1) evaluate satisfaction with the new 2023 National Institute of Health and Care Excellence (NICE) criteria for selecting total hip arthroplasty (THA) over hemiarthroplasty and surgical recommendations for treatment of displaced intracapsular hip fractures; (2) describe why THA is performed when NICE criteria are not met; and (3) determine whether satisfaction with these guidelines is associated with improved outcomes.
    METHODS: A retrospective chart review of patients who had a displaced intracapsular hip fracture treated with THA at a single tertiary academic center between 2010 and 2022 was performed. Preoperative patient characteristics were reviewed to determine if the indication for THA met NICE criteria. Operative details, perioperative complications, reoperation, and revision arthroplasty within 12 months of surgery were recorded.
    RESULTS: Data from 196 patients (63% women; age 67 ± 10 years) were used. There were 161 THAs (82.1%) that satisfied NICE criteria. The 2 most common reasons for performing a THA when NICE criteria were not met (n = 35) included preoperative radiographic osteoarthritis (Tönnis grade ≥ 2; 48.6%) and decreased patient age (< 65 years; 31.5%). Satisfaction with the NICE criteria was associated with fewer perioperative complications (0.6 versus 37.1%; P < .001), reoperations (0.6 versus 31.4%; P < .001), and revisions (0.6 versus 28.6%; P < .001). The most common reason for revision was periprosthetic fracture, possibly secondary to the use of uncemented femoral stems (171 of 196, 87.2%).
    CONCLUSIONS: Satisfaction with the new NICE criteria is associated with improved perioperative outcomes. Further studies are necessary to determine if preexisting hip osteoarthritis and younger age merit consideration in patient selection.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    髋部骨折是老年人常见的严重损伤,然而,对于直接口服抗凝药的髋部骨折患者的治疗在全球范围内仍不一致.根据现有证据和专家意见的综合,脆性骨折网络髋部骨折审核特别兴趣小组的一个工作组考虑了治疗髋部骨折和术前直接口服抗凝剂的最佳实践方法.回顾了文献和相关的临床指南,并与来自16个国家的专家小组进行了两轮改良的Delphi研究,涉及七个临床专业。达成了四个共识:对于接受直接口服抗凝药的髋部骨折患者,可以合理地进行周围神经阻滞;对于在末次剂量后<36h服用直接口服抗凝药的患者,可以合理地进行髋部骨折手术;对于在末次剂量后<36h服用直接口服抗凝药的髋部骨折患者,可以合理地进行全身麻醉(假设eGFR>60ml。min-1.1.73m-2);并且在髋部骨折手术后<48h考虑重新使用直接口服抗凝剂(考虑失血和血红蛋白)通常是合理的。关于脊髓麻醉的时机没有达成共识。制定共识声明是为了帮助临床医生做出决策,并减少髋部骨折患者和直接服用口服抗凝剂的管理实践差异。每个陈述都需要考虑到每个患者的治疗。
    Hip fracture is a common serious injury among older adults, yet the management of hip fractures for patients taking direct oral anticoagulants remains inconsistent worldwide. Drawing from a synthesis of available evidence and expert opinion, best practice approaches for managing patients with a hip fracture and who are taking direct oral anticoagulants pre-operatively were considered by a working group of the Fragility Fracture Network Hip Fracture Audit Special Interest Group. The literature and related clinical guidelines were reviewed and a two-round modified Delphi study was conducted with a panel of experts from 16 countries and involved seven clinical specialities. Four consensus statements were achieved: peripheral nerve blocks can reasonably be performed on presentation for patients with hip fracture who are receiving direct oral anticoagulants; hip fracture surgery can reasonably be performed for patients taking direct oral anticoagulants < 36 h from last dose; general anaesthesia could reasonably be administered for patients with hip fracture and who are taking direct oral anticoagulants < 36 h from last dose (assuming eGFR > 60 ml.min-1.1.73 m-2); and it is generally reasonable to consider recommencing direct oral anticoagulants (considering blood loss and haemoglobin) < 48 h after hip fracture surgery. No consensus was achieved regarding timing of spinal anaesthesia. The consensus statements were developed to aid clinicians in their decision-making and to reduce practice variations in the management of patients with hip fracture and who are taking direct oral anticoagulants. Each statement will need to be considered specific to each individual patient\'s treatment.
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  • 文章类型: Journal Article
    目的:髋部骨折患者常在急诊科就诊。尽管疼痛评分很高,院前疼痛管理往往是不充分的。在荷兰,紧急医疗服务(EMS)表现出高水平的培训,由全面的疼痛治疗方案支持。这项研究旨在评估对协议的依从性,并假设髋部骨折患者的院前疼痛管理既充分又充分。
    方法:这是一项对疑似髋部骨折患者的回顾性观察性队列研究。比较了救护车中的初始评分与到达ED时的数字评定量表(NRS)疼痛评分的中位数差异。此外,对救护车疼痛方案的依从性进行了研究。
    结果:从2016年9月到2021年3月,包括436名救护车运送的髋部骨折患者,其中81%的人通过EMS接受了镇痛药。EMS测量的初始疼痛评分中位数为8;在ED演示时,该数字降至5,显著下降(ρ<0.001)。如果评估院前NRS疼痛评分,66.5%的患者按照方案治疗。在80%的患者中,协议没有被正确遵循,主要是由于缺少NRS疼痛评分。
    结论:在疑似髋部骨折患者中,最初院前疼痛评分较高,大多数患者接受EMS止痛药.这导致疼痛的显著减少。在院前阶段评估NRS疼痛评分的患者中,近67%疼痛管理按照协议进行.然而,在80%的总人口中,疼痛方案没有得到遵守,主要是由于缺少NRS疼痛评分。
    OBJECTIVE: Patients with hip fractures frequently present at the emergency department (ED). Despite high pain scores, prehospital pain management is often inadequate and insufficient. In the Netherlands, the emergency medical services (EMS) exhibit a high level of training, supported by a comprehensive pain treatment protocol. This study aimed to assess adherence to the protocol and hypothesized that prehospital pain management in hip fracture patients was both sufficient and adequate.
    METHODS: This was a retrospective observational cohort study of patients with suspected hip fractures. The median differences in numerical rating scale (NRS) pain scores between the initial score in the ambulance and upon arrival at the ED were compared. Furthermore, adherence to the ambulance pain protocol was studied.
    RESULTS: From September 2016 to March 2021, 436 ambulance-transported hip fracture patients were included, of whom 81% received analgesics by EMS. The median initial pain score measured by EMS was 8; this number decreased to 5 at ED presentation, a significant decrease (ρ < 0.001). In case a prehospital NRS pain score was assessed, 66.5% of the patients were treated according to the protocol. In 80% of patients, the protocol was not followed correctly, primarily due to missing NRS pain scores.
    CONCLUSIONS: In suspected hip fracture patients, initial prehospital pain scores were high and most patients received analgesics from EMS. This resulted in a significant decrease in pain. In nearly 67% of patients in whom an NRS pain score was assessed in the prehospital phase, pain management was according to protocol. However, in 80% of the total population the pain protocol was not adhered to, mainly due to missing NRS pain scores.
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  • 文章类型: Randomized Controlled Trial
    目前在英国和爱尔兰,髋部骨折后,大多数患者不接受骨保护药物治疗,以降低再骨折的风险。然而,专门检查髋部骨折患者的随机对照试验数据表明,静脉注射唑来膦酸钠可将再骨折风险降低三分之一。尽管有这些证据,使用静脉注射唑来膦酸盐是高度可变的髋部骨折后;许多医院提供这种治疗,而大多数目前还没有。一系列临床不确定性,对证据基础的怀疑和实际关切被认为是原因。本文讨论了这些问题,并从专家共识中提供了指导,旨在帮助矫正儿科医生,药剂师和卫生服务管理人员建立本地协议,在患者出院前提供这种高度临床和成本效益的治疗,为了减少这个脆弱人群代价高昂的再骨折。
    Currently in the UK and Ireland, after a hip fracture most patients do not receive bone protection medication to reduce the risk of refracture. Yet randomised controlled trial data specifically examining patients with hip fracture have shown that intravenous zoledronate reduces refracture risk by a third. Despite this evidence, use of intravenous zoledronate is highly variable following a hip fracture; many hospitals are providing this treatment, whilst most are currently not. A range of clinical uncertainties, doubts over the evidence base and practical concerns are cited as reasons. This paper discusses these concerns and provides guidance from expert consensus, aiming to assist orthogeriatricians, pharmacists and health services managers establish local protocols to deliver this highly clinically and cost-effective treatment to patients before they leave hospital, in order to reduce costly re-fractures in this frail population.
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  • 文章类型: Journal Article
    髋部骨折在老年人中很常见-痴呆症患者的患病率更高。研究通常将痴呆症患者排除在外,尤其是那些处于晚期的人。因此,最合适的干预措施仍然未知.这项研究的主要目的是就为髋部骨折的晚期痴呆症患者提供物理干预所需的核心考虑达成共识。材料和方法:进行了专家共识过程,使用标称组法,探讨提供康复服务时的关键考虑因素。数据收集于2023年1月进行,涉及在线小组讨论,然后进行投票和离线评级。对共识评分进行定性内容分析和定量分析。一个由七名高度专业化的物理治疗师组成的国际小组参加了会议。
    在此过程之后,达成了59条声明。内容分析用于根据国际功能分类对这些陈述进行分类,残疾与健康。尽管共识水平很高,在几个方面存在分歧。
    这些声明提供了对多学科专业知识的总体理解,这些专业知识是有效地为该人群提供康复干预措施所必需的。痴呆症患者需要高技能和训练有素的专业人员,提供整体和以人为本的方法来提供康复干预措施。对康复的影响专家共识提供了对有效向该人群提供康复干预措施所需的多学科专业知识的总体理解。物理治疗或其他干预措施不能单独使用。痴呆症患者需要高技能和训练有素的专业人员,提供整体和以人为本的方法来提供康复干预措施。虽然我们的重点是髋部骨折,我们建议这些陈述可用于患有各种其他疾病的晚期痴呆症患者。
    UNASSIGNED: Hip fracture is common in older people - with prevalence even higher for people with dementia. Research often excludes people with dementia - especially those in the more advanced stages. Therefore, the most appropriate interventions remain unknown. The main aim of this study was to gain consensus about the core considerations needed to deliver a physical intervention for people with advanced dementia who fracture their hip. Materials and Methods: An expert consensus process was undertaken, using Nominal Group Technique, to explore the key considerations when delivering rehabilitation. Data collection was undertaken in January 2023 and involved an online group discussion followed by voting and off-line rating. Qualitative content analysis and quantitative analysis of consensus scoring was undertaken. An international group of seven highly specialised physiotherapists took part.
    UNASSIGNED: 59 statements were agreed following the process. Content analysis was used to categorise these statements according to the International Classification of Functioning, Disability and Health. Although consensus levels were high, there was disagreement in several areas.
    UNASSIGNED: The statements provide an overarching understanding of the multidisciplinary expertise that is needed to effectively deliver rehabilitation interventions to this population. People with dementia require highly skilled and trained professionals, providing holistic and person-centred approaches to deliver rehabilitation interventions.IMPLICATIONS FOR REHABILITATIONThe expert consensus provides an overarching understanding of the multidisciplinary expertise that is needed to effectively deliver rehabilitation interventions to this population.Physiotherapy - or other interventions - cannot be used in isolation.People with dementia require highly skilled and trained professionals, providing holistic and person-centred approaches to deliver rehabilitation interventions.While our focus was on hip fracture, we suggest these statements can be used for people with advanced dementia with a variety of other conditions.
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  • 文章类型: Review
    髋部骨折是老年人的主要不良事件,死亡率和发病率极高。特别是功能下降。因此,有效的髋部骨折后康复对患者恢复功能和提高生活质量至关重要。大多数髋部骨折后康复计划只关注身体功能,但是康复目标与生活质量有关,社会参与,环境问题也是至关重要的考虑因素。本研究旨在根据国际功能分类制定一套核心考虑因素,残疾,和健康(ICF),作为设计髋部骨折患者综合康复计划的参考。为此,我们招募了20名在大学医院工作的相关领域的专家,完成了三轮基于Delphi的问卷。在开始这个过程之前,进行了与ICF类别选择相关的文献综述.接下来,采用5分李克特量表对每个拟议类别的重要性进行评级,并对Spearman的等级相关系数和半四分位距指数进行了分析,以对共识状态进行评分。在第三轮基于德尔菲的问卷中,基于高水平的共识和≥4.5的平均得分,选择了ICF核心组的髋部骨折后康复考虑因素类别。选择后,ICF核心集包括34个类别,即15个身体功能,5对于身体结构,13为活动和参与,1为环境因素。提出的髋部骨折后康复ICF核心集可以作为跨学科团队制定有效康复策略和目标设定的参考。然而,进一步的可行性评估建议进行个性化康复方案设计。
    A hip fracture is a major adverse event for older individuals that has extremely high rates of mortality and morbidity, specifically functional decline. Thus, effective post-hip fracture rehabilitation is crucial to enable patients to regain function and improve their quality of life. Most post-hip fracture rehabilitation programs focus only on physical functioning, but rehabilitation goals related to the quality of life, social participation, and environmental issues are also crucial considerations. This study aimed to develop a core set of considerations based on the International Classification of Functioning, Disability, and Health (ICF) for use as a reference in designing comprehensive rehabilitation programs for patients with hip fractures. For this purpose, we recruited 20 experts from related fields working at a university hospital to complete a three-round Delphi-based questionnaire. Before beginning this process, a literature review related to ICF category selection was conducted. Next, a 5-point Likert scale was employed to rate the importance of each proposed category, and Spearman\'s rank correlation coefficient and semi-interquartile range indices were analyzed to rate the consensus status. Categories for the ICF core set of considerations for post-hip-fracture rehabilitation were chosen on the basis of a high level of consensus and a mean score of ≥4.5 in the third Delphi-based questionnaire round. After selection, the ICF core set comprised 34 categories, namely 15 for bodily functions, 5 for bodily structures, 13 for activities and participation, and 1 for environmental factors. The proposed post-hip-fracture rehabilitation ICF core set can serve as a reference for developing effective rehabilitation strategies and goal setting by interdisciplinary teams. However, further feasibility evaluation is recommended for individualized rehabilitation program design.
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  • 文章类型: Meta-Analysis
    我们对当代RCT进行了系统评价和荟萃分析,以使用基于共识的核心结果集确定脊柱与全身麻醉(SA与GA)在髋部骨折手术患者中的临床有效性。以及由患者和公众参与(PPI)计划定义为重要的结果。
    RCT比较任何核心结果(死亡率,从受伤到手术的时间,急性冠脉综合征,低血压,急性肾损伤,谵妄,肺炎,矫正输入,术后第1天下床,和疼痛)或PPI定义的结果(恢复到术前停留,生活质量,和移动性状态)从MEDLINE中识别出SA和GA之间的差异,Embase,科克伦图书馆,和WebofScience(2000年至2022年2月)。估计集合相对风险(RR)和平均差异(95%置信区间[CI])。
    SA与GA相比,谵妄的风险没有显着差异(RR=1.07;95%CI,0.90-1.29)。比较SA与GA,住院期间死亡率为0.56(95%CI,0.22-1.44),30天1.07(95%CI,0.52-2.23),90天时为1.08(95%CI,0.55-2.12)。与GA相比,脊柱麻醉降低了急性肾损伤的风险:RR=0.59(95%CI,0.39-0.89)。其他结局的风险没有显着差异。很少有研究报告PPI定义的结果,大多数研究报告一到三个核心结果。
    除了急性肾损伤,当使用基于共识的核心结局集以及患者和公众参与定义的结局时,SA和GA在髋部骨折手术中没有差异.大多数研究报告了来自核心结果集的有限结果,很少报告对患者重要的结果,在设计未来的RCT时应该考虑这一点。
    CRD42021275206。
    We conducted a systematic review and meta-analysis of contemporary RCTs to determine the clinical effectiveness of spinal vs general anaesthesia (SA vs GA) in patients undergoing hip fracture surgery using a consensus-based core outcome set, and outcomes defined as important by patient and public involvement (PPI) initiatives.
    RCTs comparing any of the core outcomes (mortality, time from injury to surgery, acute coronary syndrome, hypotension, acute kidney injury, delirium, pneumonia, orthogeriatric input, being out of bed at day 1 postoperatively, and pain) or PPI-defined outcomes (return to preoperative residence, quality of life, and mobility status) between SA and GA were identified from MEDLINE, Embase, Cochrane Library, and Web of Science (2000 to February 2022). Pooled relative risks (RRs) and mean differences (95% confidence intervals [CIs]) were estimated.
    There was no significant difference in the risk of delirium comparing SA vs GA (RR=1.07; 95% CI, 0.90-1.29). Comparing SA vs GA, the RR for mortality was 0.56 (95% CI, 0.22-1.44) in-hospital, 1.07 (95% CI, 0.52-2.23) at 30 days, and 1.08 (95% CI, 0.55-2.12) at 90 days. Spinal anaesthesia reduced the risk of acute kidney injury compared with GA: RR=0.59 (95% CI, 0.39-0.89). There were no significant differences in the risk of other outcomes. Few studies reported PPI-defined outcomes, with most studies reporting on one to three core outcomes.
    Except for acute kidney injury, there were no differences between SA and GA in hip fracture surgery when using a consensus-based core outcome set and patient and public involvement-defined outcomes. Most studies reported limited outcomes from the core outcome set, and few reported outcomes important to patients, which should be considered when designing future RCTs.
    CRD42021275206.
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  • 文章类型: Journal Article
    OBJECTIVE: Two medical specialties, general surgery and orthopaedic surgery, with different training programs but matching trauma certification requirements, provide hip fracture surgery in the Netherlands. This study analyses treatment preferences and guideline adherence of Dutch surgeons with different surgical backgrounds.
    METHODS: All hip fracture patients registered in the Dutch Hip Fracture Audit in 2018 and 2019 were included in this retrospective study. Four types of surgeons were distinguished: trauma-certified general surgeons (ST+), non-trauma certified general surgeons (ST-), trauma-certified orthopaedic surgeons (OT+) and non-trauma certified orthopaedic surgeons (OT-). Differences in patient characteristics, and practice variation in treatment choices and guideline adherence per fracture type were analysed using descriptive statistics.
    RESULTS: 28,656 patients were included; 16,367 (57.1%) treated by ST+, 1,371 (4.8%) by ST-, 4,692 (16.4%) by OT+ and 6,226 (21.7%) by OT-. Few clinically relevant differences in patient characteristics and hospital processes were found between all surgeon groups. Displaced FNF were the most commonly treated fracture type for all types of surgeons. Both OT+ and OT- operated mostly (displaced) FNFs, while the fracture types treated by ST+ and ST- were more heterogeneous. For all fracture types, the orthopaedic surgeons performed THA and HA more often than general surgeons, while general surgeons more often placed SHS and IMN for specific fracture types. Guideline adherence was on average 68.4% and differed significantly per surgeon type (68.7% by ST+, 65.2% by ST-, 74.4% by OT+ and 63.6% by OT- (p<0.01)), as well as per fracture type: >90% treatment according to the guideline for trochanteric AO-31A2 and A3 fractures, 18.8% for AO-31A1 fractures and 51.7% guideline adherence for undisplaced FNF. Guideline adherence for displaced FNF varied depending on patient characteristics.
    CONCLUSIONS: In the Netherlands, different surgical specialists treat different types of hip fractures and have different preferences concerning implants for hip fracture surgery in comparable patients. Guideline adherence of trauma- and non-trauma certified orthopaedics and general surgeons differs significantly. Reduction of practice variation should be strived for in order to improve hip fracture care.
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  • 文章类型: Journal Article
    Even though hip fracture care pathways have evolved, mortality rates have not improved during the last 20 years. This finding together with the increased frailty of hip fracture patients turned hip fractures into a major public health concern. The corresponding development of an indicator labyrinth for hip fractures and the ongoing practice variance in Europe call for a list of benchmarking indicators that allow for quality improvement initiatives for the rapid recovery of fragile hip fractures (RR-FHF). The purpose of this study was to identify quality indicators that assess the quality of in-hospital care for rapid recovery of fragile hip fracture (RR-FHF).
    A literature search and guideline selection was conducted to identify recommendations for RR-FHF. Recommendations were categorized as potential structure, process, and outcome QIs and subdivided in-hospital care treatment topics. A list of structure and process recommendations that belongs to care treatment topics relevant for RR-FHF was used to facilitate extraction of recommendations during a 2-day consensus meeting with experts (n = 15) in hip fracture care across Europe. Participants were instructed to select 5 key recommendations relevant for RR-FHF for each part of the in-hospital care pathway: pre-, intra-, and postoperative care.
    In total, 37 potential QIs for RR-FHF were selected based on a methodology using the combination of high levels of evidence and expert opinion. The set consists of 14 process, 13 structure, and 10 outcome indicators that cover the whole perioperative process of fragile hip fracture care.
    We suggest the QIs for RR-FHF to be practice tested and adapted to allow for intra-hospital longitudinal follow-up of the quality of care and for inter-hospital and cross-country benchmarking and quality improvement initiatives.
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