病毒性腹泻是儿童发病和死亡的主要原因之一。本研究旨在对漳州市病毒性腹泻进行病原学监测,福建省,中国,从2017年到2019年,以确定患病率,分布,以及该地区引起胃肠道感染的病毒病原体的特征。
■收集漳州市急性腹泻患者的粪便样本,福建省,中国,从2017年到2019年。轮状病毒,诺如病毒,星状病毒,用荧光免疫层析法检测腺病毒。
■在总共收集的5,627个样本中,至少一种病毒(轮状病毒,诺如病毒,在1,422个样本中发现星形病毒和腺病毒)呈阳性。轮状病毒,诺如病毒,星状病毒,和腺病毒,分别检测到53.73、16.68、15.52和14.97%,分别。在17.65%的阳性样本中确定了混合感染。观察到的主要混合感染是诺如病毒和星状病毒的组合,其次是轮状病毒和诺如病毒,轮状病毒和星状病毒.在12-23个月组中观察到轮状病毒和腺病毒的阳性率最高,而在6-11个月组中,诺如病毒和星状病毒的阳性率明显更高。
■这次病原学监测的这些发现突出了漳州市病毒性腹泻的重大负担,轮状病毒是主要的病原体。常见混合感染的鉴定提供了对病毒性腹泻传播的复杂性的见解。应实施目标干预措施和公共卫生战略,特别是在冬季和春季,预防和控制引起胃肠道感染的病毒病原体在该地区的传播。
UNASSIGNED: Viral diarrhea is one of the major causes of morbidity and mortality in children. This study aimed to conduct etiological surveillance of viral diarrhea in Zhangzhou city, Fujian province,
China, from 2017 to 2019 to identify the prevalence, distribution, and characteristics of viral pathogens causing gastrointestinal infections in the region.
UNASSIGNED: Stool samples were collected from patients with acute diarrhea in Zhangzhou city, Fujian province,
China, from 2017 to 2019. Rotavirus, norovirus, astrovirus, and adenovirus were detected using fluorescence immunochromatography assay.
UNASSIGNED: Of the total 5,627 samples that were collected, at least one of the viruses (rotavirus, norovirus, astrovirus and adenovirus) was found to be positive in 1,422 samples. Rotavirus, norovirus, astrovirus, and adenovirus, were detected in 53.73, 16.68, 15.52, and 14.97%, respectively. Mixed infections were determined in 17.65% of the positive samples. The predominant mixed infections observed were a combination of norovirus and astrovirus, followed by rotavirus and norovirus, and rotavirus and astrovirus. The highest positive rate was observed in the 12-23-month group for rotavirus and adenovirus, while a significantly higher positive rate was observed for norovirus and astrovirus in the 6-11-month group.
UNASSIGNED: These findings from this etiological surveillance highlight the significant burden of viral diarrhea in Zhangzhou city, with rotavirus being the predominant pathogen. The identification of common mixed infections provides insights into the complex nature of viral diarrhea transmission. Target interventions and public health strategies should be implemented, particularly during the winter and spring seasons, to prevent and control the spread of viral pathogens causing gastrointestinal infections in this region.