背景:雄激素性脱发(AGA)是一种普遍的脱发形式,影响男性和女性,严重影响患者的生活质量。传统治疗包括口服药物,局部用药,和头发移植,但这些方法都有一定的副作用和局限性。如何安全有效地最大限度地促进毛发生长一直是AGA治疗的关键问题。近年来,分割激光治疗,作为一种非侵入性方法,由于其微创和高效的性质,逐渐受到关注。
目的:在本文中,我们总结了近15年来有关AGA的点阵激光治疗的研究,并讨论了其治疗机制,临床效果,未来发展方向,以及与传统治疗方法相比在AGA治疗中的优缺点。
方法:使用PubMed进行了广泛的文献检索,Google,谷歌学者,Embase,还有Scopus.研究AGA的点阵激光治疗的所有可用文章均于2024年3月汇编。然后筛选标题和摘要的相关性,并彻底检查患者的临床结果。前瞻性临床试验,回顾性图表回顾,案例系列,和个别病例报告纳入文献综述。
结论:点阵激光治疗AGA疗效显著,安全性高。与传统治疗相比,点阵激光具有微创、快速恢复,副作用少,以及广泛的人口适用性,为AGA患者提供有效的治疗选择。进一步的大规模临床研究将有助于优化激光参数和治疗设置,以提高治疗效果。
BACKGROUND: Androgenetic alopecia (AGA) is a prevalent form of hair loss that affects both men and women, severely impacting patients\' quality of life. Traditional treatments include oral medications, topical medications, and hair transplantation, but these methods have certain side effects and limitations. How to safely effectively and maximally promote hair growth has been a key issue in the treatment of AGA. In recent years, fractionated laser therapy, as a noninvasive method, has gradually gained attention due to its minimally invasive and highly effective nature.
OBJECTIVE: In this paper, we summarized the studies related to fractional laser treatment of AGA in the past 15 years, and discussed its therapeutic mechanism, clinical effect, future development direction, and advantages and disadvantages compared with traditional treatment methods in the treatment of AGA.
METHODS: An extensive literature search was conducted using PubMed, Google, Google Scholar, Embase, and Scopus. All available articles studying fractional laser treatment of AGA were compiled in March 2024. Titles and abstracts were then screened for relevance and thoroughly examined for patient clinical outcomes. Prospective clinical trials, retrospective chart reviews, case series, and individual case reports were included in the literature review.
CONCLUSIONS: Fractional laser treatment of AGA showed remarkable efficacy and high safety. Compared with traditional treatments, fractional laser has the advantages of minimally invasive, quick recovery, fewer side effects, and a wide range of population applicability, providing an effective treatment option for AGA patients. Further large-scale clinical studies will help optimize the laser parameters and treatment settings to improve the therapeutic effect.