PDF(Pubmed)
Abstract：
OBJECTIVE: This study aimed to assess differences in various scalp parameters between patients with androgenetic alopecia (AGA) and healthy volunteers using 22 MHz ultrasound.
METHODS: Thirty patients with AGA (AGA group) and 30 healthy volunteers (control group) who visited the Department of Dermatology at the Second Affiliated Hospital of Soochow University from September 2021 to June 2022 were randomly selected. The patients with AGA met the diagnostic criteria outlined in the Chinese Guidelines for the Diagnosis and Treatment of Androgenetic Alopecia. The severity of alopecia was assessed for males between grades 2 and 4 on the Norwood-Hamilton scale, and for females between stages 2 and 3 on the Ludwig scale. No artificial interventions were conducted at the vertex, and all examination conditions remained consistent. Ultrasound examinations at 22 MHz were performed on the scalp at the vertex in both the AGA and control groups. Seven parameters were measured, namely, epidermis + dermis thickness, entire scalp thickness, subcutaneous tissue thickness, average follicle width, average follicle length, follicle count, and the presence of color flow signals in the subcutaneous tissue. The differences in these parameters were then compared.
RESULTS: The AGA group showed reduced thickness of the entire scalp and subcutaneous tissue, narrower average follicle width, shorter average follicle length, lower hair follicle count, and fewer instances of color flow signals in the subcutaneous tissue at the vertex area (p < 0.05).
CONCLUSIONS: High-frequency (22 MHz) ultrasonography can be employed to visualize the entrance echo, dermis, subcutaneous tissue, and hair follicles of the scalp, thereby providing imaging for the clinical assessment of hair loss.
METHODS: Thirty patients with AGA (AGA group) and 30 healthy volunteers (control group) who visited the Department of Dermatology at the Second Affiliated Hospital of Soochow University from September 2021 to June 2022 were randomly selected. The patients with AGA met the diagnostic criteria outlined in the Chinese Guidelines for the Diagnosis and Treatment of Androgenetic Alopecia. The severity of alopecia was assessed for males between grades 2 and 4 on the Norwood-Hamilton scale, and for females between stages 2 and 3 on the Ludwig scale. No artificial interventions were conducted at the vertex, and all examination conditions remained consistent. Ultrasound examinations at 22 MHz were performed on the scalp at the vertex in both the AGA and control groups. Seven parameters were measured, namely, epidermis + dermis thickness, entire scalp thickness, subcutaneous tissue thickness, average follicle width, average follicle length, follicle count, and the presence of color flow signals in the subcutaneous tissue. The differences in these parameters were then compared.
RESULTS: The AGA group showed reduced thickness of the entire scalp and subcutaneous tissue, narrower average follicle width, shorter average follicle length, lower hair follicle count, and fewer instances of color flow signals in the subcutaneous tissue at the vertex area (p < 0.05).
CONCLUSIONS: High-frequency (22 MHz) ultrasonography can be employed to visualize the entrance echo, dermis, subcutaneous tissue, and hair follicles of the scalp, thereby providing imaging for the clinical assessment of hair loss.
摘要：
目的：本研究旨在使用22MHz超声评估雄激素性脱发（AGA）患者与健康志愿者之间各种头皮参数的差异。
方法：随机选择2021年9月至2022年6月在苏州大学附属第二医院皮肤科就诊的30例AGA患者（AGA组）和30例健康志愿者（对照组）。AGA患者符合中国雄激素性脱发诊断和治疗指南中概述的诊断标准。在Norwood-Hamilton量表上评估了2至4级男性脱发的严重程度，以及路德维希量表上第2阶段和第3阶段之间的女性。顶点没有进行人工干预，所有检查条件保持一致。在AGA组和对照组的顶点处对头皮进行22MHz的超声检查。测量了七个参数，即,表皮+真皮厚度,整个头皮厚度,皮下组织厚度,平均卵泡宽度,平均卵泡长度,卵泡计数,以及皮下组织中颜色流信号的存在。然后比较这些参数的差异。
结果：AGA组显示整个头皮和皮下组织的厚度减少，平均卵泡宽度较窄，平均卵泡长度较短，毛囊数较低,并且在顶点区域的皮下组织中颜色流信号的实例较少(p<0.05)。
结论：可以采用高频（22MHz）超声检查来可视化入口回波，真皮,皮下组织,头皮的毛囊，从而为脱发的临床评估提供成像。
方法：随机选择2021年9月至2022年6月在苏州大学附属第二医院皮肤科就诊的30例AGA患者（AGA组）和30例健康志愿者（对照组）。AGA患者符合中国雄激素性脱发诊断和治疗指南中概述的诊断标准。在Norwood-Hamilton量表上评估了2至4级男性脱发的严重程度，以及路德维希量表上第2阶段和第3阶段之间的女性。顶点没有进行人工干预，所有检查条件保持一致。在AGA组和对照组的顶点处对头皮进行22MHz的超声检查。测量了七个参数，即,表皮+真皮厚度,整个头皮厚度,皮下组织厚度,平均卵泡宽度,平均卵泡长度,卵泡计数,以及皮下组织中颜色流信号的存在。然后比较这些参数的差异。
结果：AGA组显示整个头皮和皮下组织的厚度减少，平均卵泡宽度较窄，平均卵泡长度较短，毛囊数较低,并且在顶点区域的皮下组织中颜色流信号的实例较少(p<0.05)。
结论：可以采用高频（22MHz）超声检查来可视化入口回波，真皮,皮下组织,头皮的毛囊，从而为脱发的临床评估提供成像。
