二甲苯有可能引起神经系统紊乱,因为它是一种对富含脂质的组织具有高亲和力的亲脂性物质,比如大脑。参与脊髓,尤其是长节段脊髓病变,几乎渗透到整个颈和胸脊髓,极为罕见。我们报告了两例职业性接触过量二甲苯的病例,两者都表现出严重而迅速的四肢麻木和无力,更重要的是,导致不良结果:一个死亡,另一个严重残疾。在两者中,脊髓磁共振成像显示颈胸段脊髓长节段病变.这些发现可能为二甲苯作为分离剂对脊髓损伤的影响提供了一些见解。
Xylene has the potential to cause nervous system disturbances since it is a lipophilic substance with high affinity for lipid-rich tissue, such as the brain. Involvement in the spinal cord, especially long segmental spinal cord lesions that permeate almost the entire cervical and thoracic spinal cord, is extremely rare. We report two cases of occupational exposure to excessive
xylene, both of which presented with severe and rapidly progressive numbness and weakness in the limbs that, more importantly, led to poor outcomes: one died and the other was left severely disabled. In both, spinal magnetic resonance imaging showed long segmental lesions in the cervicothoracic spinal cord. These findings may provide some insights into the effects of
xylene as an isolated agent on the spinal cord injury.